A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Myeloperoxidase: friend and foe

Klebanoff, S. J. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.1204697 · Cited by 2,282 · see citing works

H ₂ O ₂ , a Necessary Evil for Cell Signaling

Rhee, S. G. (2006) · Science · doi:10.1126/science.1130481 · Cited by 2,160 · see citing works

Oxidative stress in neurodegeneration: Cause or consequence?

Andersen, J. K. (2004) · Nature Medicine · doi:10.1038/nrn1434 · Cited by 1,869 · see citing works

HOW NEUTROPHILS KILL MICROBES

Segal, A. W. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115653 · Cited by 1,783 · see citing works

A new trend in rhodamine-based chemosensors: application of spirolactam ring-opening to sensing ions

Kim, H. N., Lee, M. H., Kim, H. J., Kim, J. S., & Yoon, J. (2008) · Chemical Society Reviews · doi:10.1039/b802497a · Cited by 1,652 · see citing works

Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing

Hampton, M. B., Kettle, A. J., & Winterbourn, C. C. (1998) · Blood · doi:10.1182/blood.v92.9.3007.421k47_3007_3017 · Cited by 1,640 · see citing works

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

Ryu, J.-H., Kim, S.-H., Lee, H.-Y., Bai, J. Y., Nam, Y., Bae, J., Lee, D. G., Shin, S. C., Ha, E.-M., & Lee, W. (2008) · Science · doi:10.1126/science.1149357 · Cited by 832 · see citing works

A Direct Role for Dual Oxidase in Drosophila Gut Immunity

Ha, E.-M., Oh, C.-T., Bae, Y. S., & Lee, W. (2005) · Science · doi:10.1126/science.1117311 · Cited by 824 · see citing works

Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

Sugiyama, S., Okada, Y., Sukhova, G. K., Virmani, R., Heinecke, J. W., & Libby, P. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64036-9 · Cited by 699 · see citing works

Modeling the Reactions of Superoxide and Myeloperoxidase in the Neutrophil Phagosome

Winterbourn, C. C., Hampton, M. B., Livesey, J. H., & Kettle, A. J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605898200 · Cited by 633 · see citing works

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

Hazell, L. J., Arnold, L., Flowers, D., Waeg, G., Malle, E., & Stocker, R. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118576 · Cited by 592 · see citing works

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

Di, A., Brown, M. E., Deriy, L. V., Li, C., Szeto, F. L., Chen, Y., Huang, P. C., Tong, J., Naren, A. P., Bindokas, V. P., et al. (2006) · Nature Cell Biology · doi:10.1038/ncb1456 · Cited by 494 · see citing works

Development of a Highly Specific Rhodamine-Based Fluorescence Probe for Hypochlorous Acid and Its Application to Real-Time Imaging of Phagocytosis

Kenmoku, S., Urano, Y., Kojima, H., & Nagano, T. (2007) · Journal of the American Chemical Society · doi:10.1021/ja068740g · Cited by 462 · see citing works

Molecular imaging of hydrogen peroxide produced for cell signaling

Miller, E. W., Tulyathan, O., Isacoff, E. Y., & Chang, C. J. (2007) · Nature Chemical Biology · doi:10.1038/nchembio871 · Cited by 450 · see citing works

Biomarkers of myeloperoxidase-derived hypochlorous acid

Winterbourn, C. C., & Kettle, A. J. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00204-5 · Cited by 390 · see citing works

Reactions of Myeloperoxidase-Derived Oxidants with Biological Substrates:Gaining Chemical Insight into Human Inflammatory Diseases

Pattison, D. I., & Davies, M. J. (2006) · Current Medicinal Chemistry · doi:10.2174/092986706778773095 · Cited by 359 · see citing works

Visualization of nitric oxide in living cells by a copper-based fluorescent probe

Lim, M. H., Dong, X., & Lippard, S. J. (2006) · Nature Chemical Biology · doi:10.1038/nchembio794 · Cited by 353 · see citing works

A Highly Specific BODIPY-Based Fluorescent Probe for the Detection of Hypochlorous Acid

Sun, Z.-N., Liu, F., Chen, Y., Tam, P. K. H., & Yang, D. (2008) · Organic Letters · doi:10.1021/ol800507m · Cited by 341 · see citing works

Coordination of multiple dual oxidase–regulatory pathways in responses to commensal and infectious microbes in drosophila gut

Ha, E.-M., Lee, K.-A., Seo, Y. Y., Kim, S.-H., Lim, J.-H., Oh, B., Kim, J., & Lee, W. (2009) · Nature Immunology · doi:10.1038/ni.1765 · Cited by 331 · see citing works

Recent advances in fluorescent probes for the detection of reactive oxygen species

Soh, N. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0366-9 · Cited by 328 · see citing works

Hg2+ Selective Fluorescent and Colorimetric Sensor: Its Crystal Structure and Application to Bioimaging

Chen, X., Nam, S.-W., Jou, M. J., Kim, Y., Kim, S., Park, S., & Yoon, J. (2008) · Organic Letters · doi:10.1021/ol8022598 · Cited by 301 · see citing works

A Rhodamine−Hydroxamic Acid-Based Fluorescent Probe for Hypochlorous Acid and Its Applications to Biological Imagings

Yang, Y., Cho, H. J., Lee, J.-H., Shin, I., & Tae, J. (2009) · Organic Letters · doi:10.1021/ol802822t · Cited by 277 · see citing works

A Fluorescent Probe for the Detection of Myeloperoxidase Activity in Atherosclerosis-Associated Macrophages

Shepherd, J., Hilderbrand, S. A., Waterman, P. R., Heinecke, J. W., Weissleder, R., & Libby, P. (2007) · Chemistry & Biology · doi:10.1016/j.chembiol.2007.10.005 · Cited by 265 · see citing works

A Ratiometric Fluorescent Probe for Hypochlorite Based on a Deoximation Reaction

Lin, W., Long, L., Chen, B., & Tan, W. (2009) · Chemistry - A European Journal · doi:10.1002/chem.200802054 · Cited by 264 · see citing works

A Highly Selective and Sensitive Fluorescence Probe for the Hypochlorite Anion

Chen, X., Wang, X., Wang, S., Shi, W. S., Wang, K., & Ma, H. (2008) · Chemistry - A European Journal · doi:10.1002/chem.200701677 · Cited by 264 · see citing works

Role of Nox Family NADPH Oxidases in Host Defense

Leto, T. L., & Geiszt, M. (2006) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.8.1549 · Cited by 254 · see citing works

4,5-Dimethylthio-4‘-[2-(9-anthryloxy)ethylthio]tetrathiafulvalene, a Highly Selective and Sensitive Chemiluminescence Probe for Singlet Oxygen

Li, X., Zhang, G., Ma, H., Zhang, D., Li, J., & Zhu, D. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0481530 · Cited by 239 · see citing works

The influence of phorbol myristate acetate on oxygen consumption by polymorphonuclear leukocytes.

Je, R., Jg, W., Clawson, C. C., & Holmes, B. M. (1974) · PubMed · Cited by 229 · see citing works

Regulation of DUOX by the Gαq-Phospholipase Cβ-Ca2+ Pathway in Drosophila Gut Immunity

Ha, E.-M., Lee, K., Park, S. H., Kim, S., Nam, H.-J., Lee, H.-Y., Kang, D., & Lee, W. (2009) · Developmental Cell · doi:10.1016/j.devcel.2008.12.015 · Cited by 226 · see citing works

Dual oxidase in mucosal immunity and host–microbe homeostasis

Bae, Y. S., Choi, M. K., & Lee, W. (2010) · Trends in Immunology · doi:10.1016/j.it.2010.05.003 · Cited by 213 · see citing works

Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation

Panizzi, P. R., Nahrendorf, M., Wildgruber, M., Waterman, P. R., Figueiredo, J., Aïkawa, E., McCarthy, J. R., Weissleder, R., & Hilderbrand, S. A. (2009) · Journal of the American Chemical Society · doi:10.1021/ja903922u · Cited by 174 · see citing works

The respiratory burst oxidase

BABIOR, B. M. (1995) · Current Opinion in Hematology · doi:10.1097/00062752-199502010-00008 · Cited by 157 · see citing works

HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite

Tao, P., & Yang, D. (2010) · Organic Letters · doi:10.1021/ol102182j · Cited by 152 · see citing works

Roles of p38 MAPK, PKC and PI3‐K in the signaling pathways of NADPH oxidase activation and phagocytosis in bovine polymorphonuclear leukocytes

Yamamori, T., Inanami, O., Nagahata, H., Cui, Y.-D., & Kuwabara, M. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01167-4 · Cited by 151 · see citing works

A Simple and Effective Strategy To Increase the Sensitivity of Fluorescence Probes in Living Cells

Izumi, S., Urano, Y., Hanaoka, K., Terai, T., & Nagano, T. (2009) · Journal of the American Chemical Society · doi:10.1021/ja902511p · Cited by 119 · see citing works

Fluorescence ratiometric assays of hydrogen peroxide and glucose in serum using conjugated polyelectrolytes

He, F., Feng, F., Wang, S., Li, Y., & Zhu, D. (2007) · Journal of Materials Chemistry · doi:10.1039/b703856a · Cited by 70 · see citing works

Phagosomal pH Determination by Dual Fluorescence Flow Cytometry

Vergne, I., Constant, P., & Lanéelle, G. (1998) · Analytical Biochemistry · doi:10.1006/abio.1997.2466 · Cited by 60 · see citing works

Bacterial-Modulated Signaling Pathways in Gut Homeostasis

Lee, W. (2008) · Science Signaling · doi:10.1126/stke.121pe24 · Cited by 59 · see citing works

Phospholipase C Rescues Visual Defect in norpA Mutant of Drosophila melanogaster

McKay, R. R., Chen, D., Miller, K., Kim, S., Stark, W. S., & Shortridge, R. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.13271 · Cited by 53 · see citing works

Lethal of Scute requires overexpression of Daughterless to elicit ectopic neuronal development during embryogenesis in Drosophila

Giebel, B., Stüttem, I., Hinz, U., & Campos‐Ortega, J. A. (1997) · Mechanisms of Development · doi:10.1016/s0925-4773(97)00029-4 · Cited by 40 · see citing works

Anti-myeloperoxidase antibodies enhance phagocytosis, IL-8 production, and glucose uptake of polymorphonuclear neutrophils rather than anti-proteinase 3 antibodies leading to activation-induced cell death of the neutrophils

Hsieh, S., Yu, H. S., Cheng, S. H., Li, K., Lu, M., Wu, C.-H., Tsai, C., & Yu, C.-L. (2006) · Clinical Rheumatology · doi:10.1007/s10067-006-0285-3 · Cited by 28 · see citing works

Different Requirements for Early and Late Phases of Azurophilic Granule–Phagosome Fusion

Nordenfelt, P., Winberg, M. E., Lönnbro, P., Rasmusson, B. J., & Tapper, H. (2009) · Traffic · doi:10.1111/j.1600-0854.2009.00986.x · Cited by 21 · see citing works

Luminescent Chemodosimeters for Bioimaging

Yang, Y., Zhao, Q., Feng, W., & Li, F. (2012) · Chemical Reviews · doi:10.1021/cr2004103 · Cited by 2,236 · see citing works

Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives

Chen, X., Pradhan, T., Wang, F., Kim, J. S., & Yoon, J. (2011) · Chemical Reviews · doi:10.1021/cr200201z · Cited by 1,981 · see citing works

Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes

Li, X., Gao, X., Shi, W. S., & Ma, H. (2013) · Chemical Reviews · doi:10.1021/cr300508p · Cited by 1,734 · see citing works

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Chen, X., Tian, X., Shin, I., & Yoon, J. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15037e · Cited by 980 · see citing works

Reactive Oxygen Species and Neutrophil Function

Winterbourn, C. C., Kettle, A. J., & Hampton, M. B. (2016) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060815-014442 · Cited by 885 · see citing works

Fluorescent chemodosimeters using “mild” chemical events for the detection of small anions and cations in biological and environmental media

Du, J., Hu, M., Fan, J., & Peng, X. (2012) · Chemical Society Reviews · doi:10.1039/c2cs00004k · Cited by 686 · see citing works

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

Klebanoff, S. J., Kettle, A. J., Rosen, H., Winterbourn, C. C., & Nauseef, W. M. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0712349 · Cited by 679 · see citing works

Chromogenic and fluorogenic chemosensors and reagents for anions. A comprehensive review of the years 2010–2011

Santos‐Figueroa, L. E., Moragues, M. E., Climent, E., Agostini, A., Martínez‐Máñez, R., & Sancenón, F. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35429f · Cited by 594 · see citing works

Development of Targetable Two-Photon Fluorescent Probes to Image Hypochlorous Acid in Mitochondria and Lysosome in Live Cell and Inflamed Mouse Model

Yuan, L., Wang, L., Agrawalla, B. K., Park, S. J., Zhu, H., Balasubramaniam, S., Peng, J., Xu, Q., & Chang, Y. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b00042 · Cited by 557 · see citing works

Redox Reactions and Microbial Killing in the Neutrophil Phagosome

Winterbourn, C. C., & Kettle, A. J. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4827 · Cited by 468 · see citing works

ROS production in phagocytes: Why, when, and where?

Dupré-Crochet, S., Erard, M., & Nüβe, O. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.1012544 · Cited by 467 · see citing works

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

Winterbourn, C. C. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.05.004 · Cited by 420 · see citing works

A Highly Specific Fluorescent Probe for Hypochlorous Acid and Its Application in Imaging Microbe-Induced HOCl Production

Xu, Q., Lee, K.-A., Lee, S., Lee, K., Lee, W., & Yoon, J. (2013) · Journal of the American Chemical Society · doi:10.1021/ja404649m · Cited by 418 · see citing works

Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox‐mediated generation of reactive oxygen species

Jones, R. M., Luo, L., Ardita, C., Richardson, A. N., Kwon, Y. M., Mercante, J. W., Alam, A. M., Gates, C. L., Wu, H., Swanson, P. A., et al. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.224 · Cited by 393 · see citing works

Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila

Lee, K.-A., Kim, S.-H., Kim, E. K., Ha, E.-M., You, H., Kim, B., Kim, M., Kwon, Y., Ryu, J.-H., & Lee, W. (2013) · Cell · doi:10.1016/j.cell.2013.04.009 · Cited by 393 · see citing works

Design Principles, Sensing Mechanisms, and Applications of Highly Specific Fluorescent Probes for HOCl/OCl –

Wu, D., Chen, L., Xu, Q., Chen, X., & Yoon, J. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00307 · Cited by 390 · see citing works

Luminescent probes for the bioimaging of small anionic species in vitro and in vivo

Ashton, T. D., Jolliffe, K. A., & Pfeffer, F. M. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00372a · Cited by 368 · see citing works

Advances in modifying fluorescein and rhodamine fluorophores as fluorescent chemosensors

Zheng, H., Zhan, X., Bian, Q., & Zhang, X. (2012) · Chemical Communications · doi:10.1039/c2cc35997a · Cited by 346 · see citing works

Superoxide Anion Chemistry—Its Role at the Core of the Innate Immunity

Andrés, C. M. C., Pérez de la Lastra, J. M., Andrés Juan, C., Plou, F. J., & Pérez-Lebeña, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24031841 · Cited by 342 · see citing works

Small-molecule fluorophores and fluorescent probes for bioimaging

Terai, T., & Nagano, T. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1234-z · Cited by 304 · see citing works

Bacterial Responses to Reactive Chlorine Species

Gray, M. J., Wholey, W.-Y., & Jakob, U. (2013) · Annual Review of Microbiology · doi:10.1146/annurev-micro-102912-142520 · Cited by 303 · see citing works

Bioanalytical methods for hypochlorous acid detection: Recent advances and challenges

Zhang, R., Song, B., & Yuan, J. (2017) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2017.11.015 · Cited by 275 · see citing works

Recent progress in the development of fluorescent probes for the detection of hypochlorous acid

Zhang, Y., Liu, Y. M., Feng, X., & Zhao, B. (2016) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2016.08.066 · Cited by 264 · see citing works

A reversible fluorescence probe based on Se–BODIPY for the redox cycle between HClO oxidative stress and H 2 S repair in living cells

Wang, B., Li, P., Yu, F., Song, P., Sun, X., Yang, S., Lou, Z., & Han, K. (2012) · Chemical Communications · doi:10.1039/c2cc37803e · Cited by 258 · see citing works

A “turn-on” fluorescent probe for hypochlorous acid: convenient synthesis, good sensing performance, and a new design strategy by the removal of CN isomerization

Cheng, X., Jia, H., Long, T., Feng, J. X., Qin, J., & Li, Z. (2011) · Chemical Communications · doi:10.1039/c1cc15214a · Cited by 241 · see citing works

Sulfur-based fluorescent probes for HOCl: Mechanisms, design, and applications

Hou, J., Kwon, N., Wang, S., Wang, B., He, X., Yoon, J., & Shen, J. (2021) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2021.214232 · Cited by 241 · see citing works

Highly Specific and Ultrasensitive Two-Photon Fluorescence Imaging of Native HOCl in Lysosomes and Tissues Based on Thiocarbamate Derivatives

Zhu, B., Li, P., Shu, W., Wang, X., Liu, C., Wang, Y., Wang, Z., Wang, Y., & Tang, B. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04392 · Cited by 223 · see citing works

Deformylation reaction-based probe for in vivo imaging of HOCl

Wei, P., Yuan, W., Xue, F., Zhou, W. M., Li, R., Zhang, D., & Yi, T. (2017) · Chemical Science · doi:10.1039/c7sc03784h · Cited by 223 · see citing works

Development of an ICT-based ratiometric fluorescent hypochlorite probe suitable for living cell imaging

Yuan, L., Lin, W., Song, J., & Yang, Y. (2011) · Chemical Communications · doi:10.1039/c1cc15762k · Cited by 221 · see citing works

A near-infrared fluorescent probe for selective detection of HClO based on Se-sensitized aggregation of heptamethine cyanine dye

Cheng, G., Fan, J., Sun, W. C., Cao, J., Hu, C., & Peng, X. (2013) · Chemical Communications · doi:10.1039/c3cc47864e · Cited by 218 · see citing works

A reversible fluorescent probe for detecting hypochloric acid in living cells and animals: utilizing a novel strategy for effectively modulating the fluorescence of selenide and selenoxide

Lou, Z., Li, P., Pan, Q., & Han, K. (2013) · Chemical Communications · doi:10.1039/c3cc39269d · Cited by 216 · see citing works

Protein Quality Control under Oxidative Stress Conditions

Dahl, J., Gray, M. J., & Jakob, U. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.02.014 · Cited by 194 · see citing works

Recent progress in chromogenic and fluorogenic chemosensors for hypochlorous acid

Yue, Y., Huo, F., Yin, C., Escobedo, J. O., & Strongin, R. M. (2016) · The Analyst · doi:10.1039/c6an00158k · Cited by 186 · see citing works

HKOCl-2 Series of Green BODIPY-Based Fluorescent Probes for Hypochlorous Acid Detection and Imaging in Live Cells

Hu, J. J., Wong, N.-K., Gu, Q., Bai, X., Ye, S., & Yang, D. (2014) · Organic Letters · doi:10.1021/ol501496n · Cited by 186 · see citing works

Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage

Hawkins, C. L., & Davies, M. J. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.07.007 · Cited by 181 · see citing works

A Selective Imidazoline-2-thione-Bearing Two-Photon Fluorescent Probe for Hypochlorous Acid in Mitochondria

Xu, Q., Heo, C. H., Kim, J. A., Lee, H. S., Hu, Y., Kim, D., Swamy, K. M. K., Kim, G., Nam, S., Kim, H. M., et al. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b01738 · Cited by 176 · see citing works

A highly specific BODIPY-based probe localized in mitochondria for HClO imaging

Cheng, G., Fan, J., Sun, W. C., Sui, K., Jin, X., Wang, J., & Peng, X. (2013) · The Analyst · doi:10.1039/c3an01152f · Cited by 174 · see citing works

Synthesis of a highly HOCl-selective fluorescent probe and its use for imaging HOCl in cells and organisms

Chen, X., Lee, K.-A., Ren, X., Ryu, J., Kim, G., Ryu, J.-H., Lee, W., & Yoon, J. (2016) · Nature Protocols · doi:10.1038/nprot.2016.062 · Cited by 170 · see citing works

Methods to study Drosophila immunity

Neyen, C. D., Bretscher, A. J., Binggeli, O., & Lemaître, B. (2014) · Methods · doi:10.1016/j.ymeth.2014.02.023 · Cited by 164 · see citing works

Spectroscopic probes with changeable π-conjugated systems

Shi, W. S., & Ma, H. (2012) · Chemical Communications · doi:10.1039/c2cc33366j · Cited by 164 · see citing works

Mitochondria and lysosome-targetable fluorescent probes for HOCl: recent advances and perspectives

Ren, M., Zhou, K., He, L., & Lin, W. (2018) · Journal of Materials Chemistry B · doi:10.1039/c7tb03337k · Cited by 159 · see citing works

Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

Hou, J., Wu, M., Li, K., Yang, J. P., Yu, K., Xie, Y., & Yu, X. (2014) · Chemical Communications · doi:10.1039/c4cc02673j · Cited by 157 · see citing works

A fast responsive two-photon fluorescent probe for imaging H2O2 in lysosomes with a large turn-on fluorescence signal

Ren, M., Deng, B., Wang, J., Kong, X., Liu, Z.-R., Zhou, K., He, L., & Lin, W. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.12.046 · Cited by 157 · see citing works

HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay

Hu, J. J., Wong, N.-K., Lu, M.-Y., Chen, X., Ye, S., Zhao, A. Q., Gao, P., Kao, R. Y. T., Shen, J., & Yang, D. (2016) · Chemical Science · doi:10.1039/c5sc03855c · Cited by 156 · see citing works

FRET spectral unmixing: a ratiometric fluorescent nanoprobe for hypochlorite

Chen, G., Song, F., Wang, J., Yang, Z., Sun, S., Fan, J., Qiang, X., Wang, X., Dou, B., & Peng, X. (2011) · Chemical Communications · doi:10.1039/c2cc17617c · Cited by 152 · see citing works

A Ratiometric Fluorescent Probe for Sensing HOCl Based on Coumarin-rhodamine Dyad

Zhang, Y., Chen, X., Shao, J., Zhang, J.-Y., Yuan, Q., Miao, J., & Zhao, B. (2014) · Chemical Communications · doi:10.1039/c4cc05976j · Cited by 149 · see citing works

Nebraska Red: a phosphinate-based near-infrared fluorophore scaffold for chemical biology applications

Zhou, X., Lai, R., Beck, J. R., Li, H., & Stains, C. I. (2016) · Chemical Communications · doi:10.1039/c6cc05717a · Cited by 146 · see citing works

Benzothiazole-based fluorescent sensor for hypochlorite detection and its application for biological imaging

Chang, C., Wang, F., Qiang, J., Zhang, Z., Chen, Y., Zhang, W., Wang, Y., & Chen, X. (2016) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2016.11.123 · Cited by 146 · see citing works

Bacterial Uracil Modulates Drosophila DUOX-Dependent Gut Immunity via Hedgehog-Induced Signaling Endosomes

Lee, K., Kim, B., Bhin, J., Kim, D. H., You, H., Kim, E.-K., Kim, S., Ryu, J.-H., Hwang, D., & Lee, W. (2015) · Cell Host & Microbe · doi:10.1016/j.chom.2014.12.012 · Cited by 135 · see citing works

From Flies to Men: ROS and the NADPH Oxidase in Phagocytes

Moghadam, Z. M., Henneke, P., & Kolter, J. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.628991 · Cited by 136 · see citing works

Real-time detection of hypochlorite in tap water and biological samples by a colorimetric, ratiometric and near-infrared fluorescent turn-on probe

Ding, S., Zhang, Q., Xue, S., & Feng, G. (2015) · The Analyst · doi:10.1039/c5an00465a · Cited by 134 · see citing works

Fluorescent Chemosensors for Various Analytes Including Reactive Oxygen Species, Biothiol, Metal Ions, and Toxic Gases

Kwon, N., Hu, Y., & Yoon, J. (2018) · ACS Omega · doi:10.1021/acsomega.8b01717 · Cited by 133 · see citing works

Lanthanide Complex-Based Luminescent Probes for Highly Sensitive Time-Gated Luminescence Detection of Hypochlorous Acid

Xiao, Y., Zhang, R., Ye, Z., Dai, Z., An, H., & Yuan, J. (2012) · Analytical Chemistry · doi:10.1021/ac3028189 · Cited by 132 · see citing works

Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

Zhou, Y., Li, J., Chu, K.-H., Liu, K., Yao, C., & Li, J. (2012) · Chemical Communications · doi:10.1039/c2cc30265a · Cited by 127 · see citing works

A ruthenium(II) complex-based lysosome-targetable multisignal chemosensor for in vivo detection of hypochlorous acid

Cao, L., Zhang, R., Zhang, W., Du, Z., Liu, C., Ye, Z., Song, B., & Yuan, J. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.07.052 · Cited by 127 · see citing works

A self-referenced nanodosimeter for reaction based ratiometric imaging of hypochlorous acid in living cells

Wu, X., Zhu, L., Yang, L. S., Han, J., & Han, S. (2012) · Chemical Science · doi:10.1039/c2sc21485g · Cited by 125 · see citing works

Measuring chlorine bleach in biology and medicine

Kettle, A. J., Albrett, A. M., Chapman, A., Dickerhof, N., Forbes, L. V., Khalilova, I. S., & Turner, R. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.07.004 · Cited by 123 · see citing works

Analogs of Changsha near-infrared dyes with large Stokes Shifts for bioimaging

Yuan, L., Lin, W., & Chen, H. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.08.081 · Cited by 123 · see citing works

Rhodamine‐Modified Upconversion Nanophosphors for Ratiometric Detection of Hypochlorous Acid in Aqueous Solution and Living Cells

Zhou, Y., Pei, W., Wang, C., Zhu, J., Wu, J., Yan, Q., Huang, L., Huang, W., Yao, C., Loo, S. C. J., et al. (2014) · Small · doi:10.1002/smll.201303127 · Cited by 122 · see citing works

An ultra-fast illuminating fluorescent probe for monitoring formaldehyde in living cells, shiitake mushrooms, and indoors

He, L., Yang, X., Ren, M., Kong, X., Liu, Y., & Lin, W. (2016) · Chemical Communications · doi:10.1039/c6cc04254f · Cited by 117 · see citing works

A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

Reja, S. I., Bhalla, V., Sharma, A., Kaur, G., & Kumar, M. (2014) · Chemical Communications · doi:10.1039/c4cc05356g · Cited by 115 · see citing works

Organoselenium compounds as fluorescent probes

Panda, S., Panda, A., & Zade, S. S. (2015) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2015.04.006 · Cited by 112 · see citing works

Visualization of Endogenous and Exogenous Hydrogen Peroxide Using A Lysosome-Targetable Fluorescent Probe

Kim, D., Kim, G., Nam, S., Yin, J., & Yoon, J. (2015) · Scientific Reports · doi:10.1038/srep08488 · Cited by 110 · see citing works

Recent Progress in Fluorescent Imaging Probes

Pak, Y. L., Swamy, K. C. K., & Yoon, J. (2015) · Sensors · doi:10.3390/s150924374 · Cited by 108 · see citing works

Enhanced Fluorescence Turn‐on Imaging of Hypochlorous Acid in Living Immune and Cancer Cells

Mulay, S. V., Choi, M., Jang, Y. J., Kim, Y., Jon, S., & Churchill, D. G. (2016) · Chemistry - A European Journal · doi:10.1002/chem.201601270 · Cited by 107 · see citing works

A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

Guo, T., Cui, L., Shen, J., Wang, R., Zhu, W. P., Xu, Y. F., & Qian, X. H. (2013) · Chemical Communications · doi:10.1039/c3cc38471c · Cited by 107 · see citing works

Small-Molecule-Based Fluorescent Sensors for Selective Detection of Reactive Oxygen Species in Biological Systems

Bai, X., Ng, K. K. ‐., Hu, J. J., Ye, S., & Yang, D. (2019) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-013118-111754 · Cited by 104 · see citing works

Ratiometric fluorescence imaging of cellular hypochlorous acid based on heptamethine cyanine dyes

Lou, Z., Li, P., Song, P., & Han, K. (2013) · The Analyst · doi:10.1039/c3an00198a · Cited by 104 · see citing works

The DH31/CGRP enteroendocrine peptide triggers intestinal contractions favoring the elimination of opportunistic bacteria

Benguettat, O., Jneid, R., Soltys, J., Loudhaief, R., Brun‐Barale, A., Osman, D., & Gallet, A. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1007279 · Cited by 104 · see citing works

Antimicrobial actions of dual oxidases and lactoperoxidase

Sarr, D., Tóth, E., Gingerich, A., & Rada, B. (2018) · Journal of Microbiology · doi:10.1007/s12275-018-7545-1 · Cited by 98 · see citing works

A new rhodamine derivative bearing benzothiazole and thiocarbonyl moieties as a highly selective fluorescent and colorimetric chemodosimeter for Hg2+

Wang, F., Nam, S.-W., Guo, Z., Park, S., & Yoon, J. (2011) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2011.11.070 · Cited by 99 · see citing works

Transient adult microbiota, gut homeostasis and longevity: Novel insights from the Drosophila model

Erkoşar, B., & Leulier, F. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.06.041 · Cited by 99 · see citing works

Fluorescent Probes Containing Selenium as a Guest or Host

Wu, D., Chen, L., Kwon, N., & Yoon, J. (2016) · Chem · doi:10.1016/j.chempr.2016.10.005 · Cited by 98 · see citing works

Functional Enzyme Mimics for Oxidative Halogenation Reactions that Combat Biofilm Formation

Herget, K., Frerichs, H., Pfitzner, F., Tahir, M. N., & Tremel, W. (2018) · Advanced Materials · doi:10.1002/adma.201707073 · Cited by 98 · see citing works

Highly reactive (<1 min) ratiometric “naked eye” detection of hypochlorite with real application in tap water

Goswami, S., Paul, S., & Manna, A. (2013) · Dalton Transactions · doi:10.1039/c3dt51238j · Cited by 97 · see citing works

Turn-on Fluorescent Probe for Exogenous and Endogenous Imaging of Hypochlorous Acid in Living Cells and Quantitative Application in Flow Cytometry

Zhan, Z., Liu, R., Chai, L., Li, Q., Zhang, K., & Lv, Y. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b02613 · Cited by 96 · see citing works

The RclR Protein Is a Reactive Chlorine-specific Transcription Factor in Escherichia coli

Parker, B. W., Schwessinger, E. A., Jakob, U., & Gray, M. J. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.503516 · Cited by 95 · see citing works

A mitochondria-targeted fluorescent probe for ratiometric detection of hypochlorite in living cells

Chen, Y., Wei, T., Zhang, Z., Zhang, W., Lv, J. H., Chen, T., Chi, B., Wang, F., & Chen, X. (2017) · Chinese Chemical Letters · doi:10.1016/j.cclet.2017.05.010 · Cited by 94 · see citing works

Sensors, Imaging Agents, and Theranostics to Help Understand and Treat Reactive Oxygen Species Related Diseases

Yan, K., Sedgwick, A. C., Zang, Y., Chen, G., He, X., Li, J. X., Yoon, J., & James, T. D. (2019) · Small Methods · doi:10.1002/smtd.201900013 · Cited by 87 · see citing works

Development of a Ruthenium(II) Complex-Based Luminescent Probe for Hypochlorous Acid in Living Cells

Zhang, R., Ye, Z., Song, B., Dai, Z., An, X., & Yuan, J. (2013) · Inorganic Chemistry · doi:10.1021/ic400767u · Cited by 84 · see citing works

A highly selective colorimetric probe for fast and sensitive detection of hypochlorite in absolute aqueous solution

Zhu, B., Xu, Y., Liu, W., Shao, C., Wu, H., Jiang, H., Du, B., & Zhang, X. (2013) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2013.10.057 · Cited by 84 · see citing works

Rapid and ratiometric detection of hypochlorite with real application in tap water: molecules to low cost devices (TLC sticks)

Goswami, S., Manna, A., Paul, S., Quah, C. K., & Fun, H. (2013) · Chemical Communications · doi:10.1039/c3cc47121g · Cited by 83 · see citing works

TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway

Du, E. J., Ahn, T. J., Kwon, I., Lee, J. H., Park, J.-H., Park, S. H., Kang, T. M., Cho, H., Kim, T. J., Kim, H.-W., et al. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1005773 · Cited by 83 · see citing works

Antiviral innate immune response in non-myeloid cells is augmented by chloride ions via an increase in intracellular hypochlorous acid levels

Ramalingam, S., Cai, B., Wong, J., Twomey, M., Chen, R., Fu, R., Boote, T., McCaughan, H., Griffiths, S. J., & Haas, J. (2018) · Scientific Reports · doi:10.1038/s41598-018-31936-y · Cited by 81 · see citing works

An acid catalyzed reversible ring-opening/ring-closure reaction involving a cyano-rhodamine spirolactam

Li, H., Guan, H., Duan, X., Hu, J., Wang, G., & Wang, Q. (2013) · Organic & Biomolecular Chemistry · doi:10.1039/c3ob27356c · Cited by 81 · see citing works

A water-soluble and specific BODIPY-based fluorescent probe for hypochlorite detection and cell imaging

Wu, G., Zeng, F., & Wu, S. (2013) · Analytical Methods · doi:10.1039/c3ay41268g · Cited by 79 · see citing works

A ratiometric fluorescence probe based on a novel FRET platform for imaging endogenous HOCl in the living cells

Zhang, Y., Zhao, Z., Miao, J., & Zhao, B. (2016) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2016.01.146 · Cited by 79 · see citing works

Luminescent probes for hypochlorous acid in vitro and in vivo

Dong, S., Zhang, L., Lin, Y., Ding, C., & Lu, C. (2020) · The Analyst · doi:10.1039/d0an00645a · Cited by 76 · see citing works

A lysosome-targeted ratiometric fluorescent probe for detection of hypochlorous acid in living cells

Yuan, Q., Zhao, Z., Zhang, Y., Su, L., Miao, J., & Zhao, B. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.03.049 · Cited by 73 · see citing works

A mitochondria-targeted fluorescent probe based on fluorescein derivative for detection of hypochlorite in living cells

Lv, J., Chen, Y., Wang, F., Wei, T., Zhang, Z., Qiang, J., & Chen, X. (2017) · Dyes and Pigments · doi:10.1016/j.dyepig.2017.09.037 · Cited by 70 · see citing works

Two novel fluorescein-based fluorescent probes for hypochlorite and its real applications in tap water and biological imaging

Jin, X., Hao, L., Hu, Y., She, M., Shi, Y., Obst, M., Li, J., & Shi, Z. (2013) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2013.05.079 · Cited by 71 · see citing works

A new resorufin-based spectroscopic probe for simple and sensitive detection of benzoyl peroxide via deboronation

Chen, W., Zhao, L., Shi, W. S., & Ma, H. (2012) · Chemical Communications · doi:10.1039/c2cc17768d · Cited by 71 · see citing works

Fluorescence probe for hypochlorous acid in water and its applications for highly lysosome-targetable live cell imaging

Jiao, X., Liu, C., Wang, Q., Huang, K., He, S., Zhao, L., & Zeng, X. (2017) · Analytica Chimica Acta · doi:10.1016/j.aca.2017.03.020 · Cited by 71 · see citing works

Ratiometric detection of hypochlorite applying the restriction to 2-way ESIPT: simple design for “naked-eye” tap water analysis

Manna, A., & Goswami, S. (2015) · New Journal of Chemistry · doi:10.1039/c5nj00307e · Cited by 70 · see citing works

A highly specific pyrene-based fluorescent probe for hypochlorite and its application in cell imaging

Zang, L., Liang, C., Wang, Y., Bu, W., Sun, H., & Jiang, S. (2015) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2015.01.046 · Cited by 69 · see citing works

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

Cabello, M. C., Chen, G., Melville, M. J., Osman, R., Kumar, G., Domaille, D. W., & Lippert, A. R. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00892 · Cited by 67 · see citing works

Novel water soluble styrylquinolinium boronic acid as a ratiometric reagent for the rapid detection of hypochlorite ion

Wang, Q., Liu, C., Chang, J., Lu, Y., He, S., Zhao, L., & Zeng, X. (2013) · Dyes and Pigments · doi:10.1016/j.dyepig.2013.06.019 · Cited by 65 · see citing works

Highly Sensitive and Selective Fluorescent Probes for the Detection of HOCl/OCl– Based on Fluorescein Derivatives

Lv, J., Wang, F., Wei, T., & Chen, X. (2017) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.7b00381 · Cited by 65 · see citing works

A rhodamine B-based probe for the detection of HOCl in lysosomes

Shen, S., Huang, X., Jiang, H., Lin, X., & Cao, X. (2018) · Analytica Chimica Acta · doi:10.1016/j.aca.2018.09.054 · Cited by 65 · see citing works

Ratiometric Signaling of Hypochlorite by the Oxidative Cleavage of Sulfonhydrazide-Based Rhodamine–Dansyl Dyad

Lee, H. J., Cho, M. J., & Chang, S. (2015) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.5b01284 · Cited by 63 · see citing works

A Highly Specific Fluorescent Probe for Hypochlorous Acid and Its Application in Imaging Microbe-Induced HOCl Production

Xu, Q., Lee, K.-A., Lee, S., Lee, K., Lee, W., & Yoon, J. (2013) · Journal of the American Chemical Society · doi:10.1021/ja404649m · Cited by 418 · see citing works

A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice

Zhang, Y., Ma, L., Tang, C., Pan, S., Shi, D., Wang, S., Li, M., & Guo, Y. (2018) · Journal of Materials Chemistry B · doi:10.1039/c7tb02862h · Cited by 76 · see citing works

A hypochlorous acid turn-on fluorescent probe based on HOCl-promoted oxime oxidation and its application in cell imaging

Yu, S.-Y., Hsu, C.-Y., Chen, W.-C., Wei, L.-F., & Wu, S. (2014) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2014.01.121 · Cited by 95 · see citing works

Turn-on Fluorescent Probe for Exogenous and Endogenous Imaging of Hypochlorous Acid in Living Cells and Quantitative Application in Flow Cytometry

Zhan, Z., Liu, R., Chai, L., Li, Q., Zhang, K., & Lv, Y. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b02613 · Cited by 96 · see citing works

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

Song, Z., Yuan, Q., Lv, P., & Chen, K. (2021) · Sensors · doi:10.3390/s21196326 · Cited by 54 · see citing works