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A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease

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Hydrogen peroxide mediates amyloid β protein toxicity

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Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System

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Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

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Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

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Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease

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Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains

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Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

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Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease

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Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

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Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct

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Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

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Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

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Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

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Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70

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Minocycline Prevents Nigrostriatal Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease

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Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

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Parkinson's disease: A disorder due to nigral glutathione deficiency?

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Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis

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α-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress

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Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death1

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Dopamine Oxidation Alters Mitochondrial Respiration and Induces Permeability Transition in Brain Mitochondria

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Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease

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Benefit of vitamin E, riluzole, and gababapentin in a transgenic model of familial amyotrophic lateral sclerosis

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Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo

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Mutated Human SOD1 Causes Dysfunction of Oxidative Phosphorylation in Mitochondria of Transgenic Mice

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Increased 3‐nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

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Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

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The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity

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Protein Nitration in Parkinsonʼs Disease

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Epidemiology of mutations in superoxide dismutase in amyotrophic lateal sclerosis

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Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

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Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

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Electrochemical Analysis of Protein Nitrotyrosine and Dityrosine in the Alzheimer Brain Indicates Region-Specific Accumulation

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Inflammatory Regulators in Parkinson's Disease: iNOS, Lipocortin-1, and Cyclooxygenases-1 and -2

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Vesicle Permeabilization by Protofibrillar α-Synuclein Is Sensitive to Parkinson's Disease-Linked Mutations and Occurs by a Pore-like Mechanism

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A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide.

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Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

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Motoneuron Death Triggered by a Specific Pathway Downstream of Fas

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Protein modification by the lipid peroxidation product 4‐hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

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Conjugates of Catecholamines with Cysteine and GSH in Parkinson's Disease: Possible Mechanisms of Formation Involving Reactive Oxygen Species

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Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease.

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Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients

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Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

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Monomeric Cu,Zn-superoxide Dismutase Is a Common Misfolding Intermediate in the Oxidation Models of Sporadic and Familial Amyotrophic Lateral Sclerosis

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Deficiency of Inducible Nitric Oxide Synthase Protects Against MPTP Toxicity In Vivo

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4-Hydroxy-2-nonenal-mediated Impairment of Intracellular Proteolysis during Oxidative Stress

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Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease

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Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS

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Differential expression of inflammation‐ and apoptosis‐related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis

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Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide _1–42 - and Lipopolysaccharide-Activated Microglia

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ALS-Linked Cu/Zn–SOD Mutation Increases Vulnerability of Motor Neurons to Excitotoxicity by a Mechanism Involving Increased Oxidative Stress and Perturbed Calcium Homeostasis

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Mutant SOD1 causes motor neuron disease independent of copper chaperone–mediated copper loading

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Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

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CEP-1347/KT-7515, an Inhibitor of c-jun N-Terminal Kinase Activation, Attenuates the 1-Methyl-4-Phenyl Tetrahydropyridine-Mediated Loss of Nigrostriatal Dopaminergic Neurons In Vivo

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A double-blind, placebo-controlled randomized clinical trial of α-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis

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Up‐Regulation of Protein Chaperones Preserves Viability of Cells Expressing Toxic Cu/Zn‐Superoxide Dismutase Mutants Associated with Amyotrophic Lateral Sclerosis

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Inhibition of the multicatalytic proteinase (proteasome) by 4‐hydroxy‐2‐nonenal cross‐linked protein

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Decrease in Peptide Methionine Sulfoxide Reductase in Alzheimer's Disease Brain

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Glutathione Depletion in PC12 Results in Selective Inhibition of Mitochondrial Complex I Activity

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α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

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MPTP Activates c‐Jun NH2‐Terminal Kinase (JNK) and Its Upstream Regulatory Kinase MKK4 in Nigrostriatal Neurons In Vivo

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Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

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Nitration of Tau Protein Is Linked to Neurodegeneration in Tauopathies

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Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

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Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein.

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The Copper Chelator d‐Penicillamine Delays Onset of Disease and Extends Survival in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis

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Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression

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Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis

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Increased MPTP Neurotoxicity in Vesicular Monoamine Transporter 2 Heterozygote Knockout Mice

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Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways.

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Neurotoxic Mechanisms Caused by the Alzheimer's Disease-linked Swedish Amyloid Precursor Protein Mutation

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Effect of Wild-type or Mutant Parkin on Oxidative Damage, Nitric Oxide, Antioxidant Defenses, and the Proteasome

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