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A review of the efficacy of dietary polyphenols in experimental models of inflammatory bowel diseases
Abstract
The use of polyphenols in rodent models of inflammatory bowel diseases is reviewed. Many polyphenols inhibit colitis through multiple mechanisms, however higher doses of some treatments may exacerbate inflammation.
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“The polyphenol curcumin, derived from turmeric, has been shown to have anti-inflammatory, antioxidant, antimicrobial, and immunomodulatory effects in some in vitro and animal studies (Amalraj et al., 2017;Martin & Bolling, 2015), demonstrating potential as a treatment for digestive disorders (Dulbecco & Savarino, 2013).”
From A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders (2024) · cites this paper as Martin & Bolling, 2015
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Polyphenols: Food sources and bioavailability
Manach, C., Scalbert, A., Morand, C., Rémésy, C., & Jiménez, L. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.727 · Cited by 8,175
Dose translation from animal to human studies revisited.
Reagan‐Shaw, S., Nihal, M., & Ahmad, N. (2008) · The FASEB Journal · doi:10.1096/fj.07-9574lsf · Cited by 6,524
Bioavailability of curcumin: Problems and promises
Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007) · Molecular Pharmaceutics · doi:10.1021/mp700113r · Cited by 5,543
Intestinal mucosal barrier function in health and disease
Turner, J. R. (2009) · Nature reviews. Immunology · doi:10.1038/nri2653 · Cited by 3,952
Abraham, C., & Cho, J. H. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804647 · Cited by 2,712
How informative is the mouse for human gut microbiota research?
Nguyen, T. L. A., Vieira-Silva, S., Liston, A., & Raes, J. (2015) · Disease Models & Mechanisms · doi:10.1242/dmm.017400 · Cited by 1,334
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Larrosa, M., Yañéz-Gascón, M. J., Selma, M. V., González-Sarrías, A., Toti, S., Cerón, J. J., Tomás-Barberán, F., Dolara, P., & Espín, J. C. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf803638d · Cited by 365
Dou, W., Zhang, J., Zhang, E., Sun, A., Ding, L., Chou, G., Wang, Z., & Mani, S. (2013) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.112.201863 · Cited by 111
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Cited by
A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders
Thavorn, K., Wolfe, D., Faust, L., Shorr, R., Akkawi, M., Isaranuwatchai, W., Klinger, C., Chai‐Adisaksopa, C., Tanvejsilp, P., Nochaiwong, S., et al. (2024) · Phytotherapy Research · doi:10.1002/ptr.8189 · Cited by 11
Metadata
- Authors
- Martin, D. A., & Bolling, B. W.
- Affiliations
- Department of Food Science
- Venue
- Food & Function
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 6
- Issue
- 6
- Pages
- 1773-1786
- ISSN
- 2042-6496
- 2042-650X
- Cited by
- 133
- References
- 9
- Language
- en
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