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Cited by 501

The DOI matches its Crossref record; 139 of the 139 references it cites were found in a registry or an index.

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

Open access
Dabrowski, Janusz M., Arnaut, Luis G.·2015·Photochemical & Photobiological Sciences

Abstract

Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and adequate use of both to trigger biological mechanisms that can rapidly destroy the primary tumour and provide long-lasting protection against metastasis. We present a multidisciplinary view of the issues raised by the development of PDT. We show how spectroscopy, photophysics, photochemistry and pharmacokinetics of photosensitizers determine the mechanism of cell death and clinical protocols. Various examples of combinations with chemotherapies and immunotherapies illustrate the opportunities to potentiate the outcome of PDT. Particular emphasis is given to the mechanisms that can be exploited to establish PDT as a systemic treatment of solid tumours and metastatic disease.

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Registry

Crossref · 10.1039/c5pp00132c

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Metadata

Authors
Dabrowski, J. M., & Arnaut, L. G.
Venue
Photochemical & Photobiological Sciences
Published
2015-10
Volume
14
Issue
10
Pages
1765-1780
ISSN
  • 1474-905X (ISSN-L)
  • 1474-9092
OpenAlex
W1909548258
Cited by
501
References
139
FWCI
24.97
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Photodynamic therapy (PDT) of cancer: from local to systemic treatment. https://app.cochat.ai/papers/10.1039/c5pp00132c
The paper
Dabrowski, J. M., & Arnaut, L. G. (2015). Photodynamic therapy (PDT) of cancer: from local to systemic treatment. Photochemical & Photobiological Sciences. https://doi.org/10.1039/c5pp00132c

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.