Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

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Targeting hypoxia in cancer therapy

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Fluorescent chemosensors: the past, present and future

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Profiling Enzyme Activities In Vivo Using Click Chemistry Methods

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Alkaline Phosphatases

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Real-Time Monitoring of Cell Apoptosis and Drug Screening Using Fluorescent Light-Up Probe with Aggregation-Induced Emission Characteristics

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Specific Light‐Up Bioprobe with Aggregation‐Induced Emission and Activatable Photoactivity for the Targeted and Image‐Guided Photodynamic Ablation of Cancer Cells

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Ultrasensitive Near-Infrared Fluorescence-Enhanced Probe for in Vivo Nitroreductase Imaging

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Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

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Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

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Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

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Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2

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Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ

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Rapid Cancer Detection by Topically Spraying a γ-Glutamyltranspeptidase–Activated Fluorescent Probe

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Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes

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The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins

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Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities

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Caspases and cancer

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Targeting tumor-associated carbonic anhydrase IX in cancer therapy

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Fluorescent probes for the simultaneous detection of multiple analytes in biology

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Strategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors

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Leucine aminopeptidases: diversity in structure and function

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Hypoxia-Sensitive Fluorescent Probes for in Vivo Real-Time Fluorescence Imaging of Acute Ischemia

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Dynamic imaging of protease activity with fluorescently quenched activity-based probes

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A Ratiometric Fluorescent Probe Based on ESIPT and AIE Processes for Alkaline Phosphatase Activity Assay and Visualization in Living Cells

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An Off–On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells

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Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

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Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor

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Highly Selective Off–On Fluorescent Probe for Imaging Thioredoxin Reductase in Living Cells

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Radical Ideas about Monoamine Oxidase

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A Bright Future for Precision Medicine: Advances in Fluorescent Chemical Probe Design and Their Clinical Application

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Aberrant glycosylation associated with enzymes as cancer biomarkers

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β-Galactosidase Fluorescence Probe with Improved Cellular Accumulation Based on a Spirocyclized Rhodol Scaffold

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In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides

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Cell-Permeable and Biocompatible Polymeric Nanoparticles for Apoptosis Imaging

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Near‐Infrared Fluorescent Probe with New Recognition Moiety for Specific Detection of Tyrosinase Activity: Design, Synthesis, and Application in Living Cells and Zebrafish

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Improved Quenched Fluorescent Probe for Imaging of Cysteine Cathepsin Activity

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Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting

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In Situ Localization of Enzyme Activity in Live Cells by a Molecular Probe Releasing a Precipitating Fluorochrome

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Fluorescent Light-up Probe with Aggregation-Induced Emission Characteristics for Alkaline Phosphatase Sensing and Activity Study

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A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models

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A mitochondrial-targeted prodrug for NIR imaging guided and synergetic NIR photodynamic-chemo cancer therapy

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