Effects of n-3 fatty acid supplements on cardiometabolic profiles in hypertensive patients with abdominal obesity in Inner Mongolia: a randomized controlled trial
Abstract
Daily supplementation with n-3 fatty acid (FA) has been believed to be an adjunct or alternative to drug treatments to reduce blood pressure (BP) and triglyceride (TG) levels in western patients with high risk of cardiovascular disease.
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Six RCTs had low risk of bias for random sequence generation, three had high risk, and the remaining had unclear risk.
“Six RCTs indicated the method for random sequence generation was low risk [29, 34, 44, 47, 48, 52], three other studies indicated high risk [21, 41, 53], and the remaining studies have unclear risk of bias.”
From Comparisons of the effects of different flaxseed products consumption on lipid profiles, inflammatory cytokines and anthropometric indices in patients with dyslipidemia related diseases: systematic review and a dose-response meta-analysis of randomized controlled trials (2021) · cites this paper as [29]
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- Authors
- Yang, B., Shi, M.-Q., Li, Z.-H., Shi, L., Wang, A.-M., Guo, X.-J., & Li, D.
- Affiliations
- Wenzhou Medical University (CN)
- Zhejiang University (CN)
- Department of Food Science and Nutrition
- Ejin Horo Banner Centre for Disease Prevention and Control
- Institute of Lipids Medicine
- Qingdao University (CN)
- Corresponding author
- Li, Duo
- Venue
- Food & Function
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2019
- Volume
- 10
- Issue
- 3
- Pages
- 1661-1670
- ISSN
- 2042-6496 (ISSN-L)
- 2042-650X
- OpenAlex
- W2911409859
- Cited by
- 28
- References
- 45
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 5 · 2019: 3
- FWCI
- 3.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food & Function (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wenzhou Medical University (89217015)
- China Medical University Hospital (CRS-106-063)
- National Basic Research Program of China (2015CB553604)
- National Natural Science Foundation of China (81773433)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- omega-3 fatty acids, fish oil, linseed oil, abdominal obesity, hypertension, cardiometabolic risk, blood pressure, LDL cholesterol, apolipoprotein B, triglycerides, waist circumference, fasting blood glucose, insulin, eicosapentaenoic acid, docosahexaenoic acid, alpha-linolenic acid, Chinese adults, Inner Mongolia, corn oil
- MeSH terms
- Adult, Aged, Female, Humans, Hypertension, Male, Middle Aged, Fatty Acids, Omega-3, Obesity, Abdominal
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