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Flexible polymeric nanosized micelles for ophthalmic drug delivery: research progress in the last three years

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Current status and future of delivery systems for prevention and treatment of infections in the oral cavity

Şenel, S., Özdoğan, A. I., & Akca, G. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00961-2 · Cited by 44 · see citing works

The Thermogel Chronicle─From Rational Design of Thermogelling Copolymers to Advanced Thermogel Applications

Lin, Q., Owh, C., Lim, J. Y. C., Chee, P. L., Yew, M. P. Y., Hor, E. T. Y., & Loh, X. J. (2021) · Accounts of Materials Research · doi:10.1021/accountsmr.1c00128 · Cited by 44 · see citing works

Fabrication and evaluation of Cs/PVP sponge containing platelet-rich fibrin as a wound healing accelerator: An in vitro and in vivo study

Tavakoli, M., Mirhaj, M., Labbaf, S., Varshosaz, J., Taymori, S., Jafarpour, F., Salehi, S., Abadi, S. A. M., & Sepyani, A. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.02.003 · Cited by 44 · see citing works

Hydrogel – based biopolymers for regenerative medicine applications: a critical review

Ebhodaghe, S. O. (2020) · International Journal of Polymeric Materials · doi:10.1080/00914037.2020.1809409 · Cited by 43 · see citing works

Novel Functional Dressing Materials for Intraoral Wound Care

Ding, Y., Zhu, Z., Zhang, X., & Wang, J. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400912 · Cited by 41 · see citing works

PCL-Based Thermogelling Polymer: Molecular Weight Effects on Its Suitability as Vitreous Tamponade

Xue, K., Liu, Z., Lin, Q., Lim, J. Y. C., Tang, K. Y., Wong, S. L., Parikh, B. H., Su, X., & Loh, X. J. (2020) · ACS Applied Bio Materials · doi:10.1021/acsabm.0c01266 · Cited by 41 · see citing works

Recent Advances in Enzyme‐Based Biomaterials Toward Diabetic Wound Healing

Wang, Q., Luo, Z., Wu, Y., & Li, Z. (2022) · Advanced NanoBiomed Research · doi:10.1002/anbr.202200110 · Cited by 40 · see citing works

Chitosan-CaP microflowers and metronidazole loaded calcium alginate sponges with enhanced antibacterial, hemostatic and osteogenic properties for the prevention of dry socket after tooth removal

Yan, M., Pan, Y., Lu, S., Li, X., Wang, D., Shao, T., Wu, Z., & Zhou, Q. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.05.094 · Cited by 38 · see citing works

A polyglutamic acid/tannic acid-based nano drug delivery system: Antibacterial, immunoregulation and sustained therapeutic strategies for oral ulcers

He, S., Bai, J., Liu, Y., Zeng, Y., Wang, L., Chen, X., Wang, J., Weng, J., Zhao, Y., Peng, W., et al. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.123607 · Cited by 29 · see citing works

Dual-light defined in situ oral mucosal lesion therapy through a mode switchable anti-bacterial and anti-inflammatory mucoadhesive hydrogel

Liu, H., Li, Q., Xu, Y., Sun, Y., Fan, X., Fang, H., Hu, B., Huang, L., Liao, L., & Wang, X. (2023) · Biomaterials Science · doi:10.1039/d2bm01721k · Cited by 28 · see citing works

A molybdenum sulfide based nitric oxide controlled release oral gel for rapid healing of oral mucosal ulcers

Cheng, H., Tian, G., Liu, H., Bai, D., Zhang, Y., Wang, Q., Zhao, M., Cao, S., Deng, D., & Wang, X. (2024) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2024.08.210 · Cited by 26 · see citing works

A cell-free SHED lysate-hydrogel system for oral ulcer healing with anti-inflammatory and pro-angiogenic effects

Dong, N., Zhang, C., Zhang, Q., Bao, S., Hu, Y., Xu, H., Dai, P., Li, C., Li, S., Wu, P., et al. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03597-3 · Cited by 24 · see citing works

A novel thermoresponsive nano carrier matrix of hyaluronic acid, methotrexate and chitosan to target the cluster of differentiation 44 receptors in tumors

Gupta, C. R., Singh, P. R., Vaidya, S. P., Ambre, P., & Coutinho, E. C. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125238 · Cited by 23 · see citing works

Marine collagen peptides: A novel biomaterial for the healing of oral mucosal ulcers

Gao, Q., Shang, Y., Zhou, W., Deng, S., & Peng, C. (2022) · Dental Materials Journal · doi:10.4012/dmj.2021-323 · Cited by 22 · see citing works

PEG-free pH-Responsive Thermogels Containing Amphiphilic Polycationic Polyethylenimine Copolymers

Lin, Q., Lim, C. C., Owh, C., Wong, J. H. M., Ow, V., Sim, B., Boo, Y. J., Yew, M. P. Y., Leow, Y., Guo, L., et al. (2023) · Macromolecules · doi:10.1021/acs.macromol.3c01600 · Cited by 20 · see citing works

Zinc diethyldithiocarbamate as a catalyst for synthesising biomedically-relevant thermogelling polyurethanes

Lim, J. Y. C., Lin, Q., Liu, C. K., Guo, L., Xue, K., & Loh, X. J. (2020) · Materials Advances · doi:10.1039/d0ma00734j · Cited by 20 · see citing works

Bioactive Functionalized Chitosan Thermo‐Responsive Hydrogels as Promising Platforms for Therapeutic, Regenerative Oral, and Maxillofacial Applications

Alkandari, M., Barai, P., Atia, G. A. N., Mohamed, S. Z., Ghobashy, M. M., Shalaby, H. K., Foda, T., Rabbee, M. F., Mallick, S., Barai, H. R., et al. (2025) · Biotechnology Journal · doi:10.1002/biot.202400653 · Cited by 18 · see citing works

Supramolecular thermogels from branched PCL-containing polyurethanes

Lin, Q., Lim, J. Y. C., Xue, K., Chee, C. P. T., & Loh, X. J. (2020) · RSC Advances · doi:10.1039/d0ra07426h · Cited by 17 · see citing works

Effects of a semi-interpenetrating network hydrogel loaded with oridonin and DNase-I on the healing of chemoradiotherapy-induced oral mucositis

Pan, Y., Wang, M., Wang, P., Wei, H., Wei, X., Wang, D., Hao, Y., Wang, Y., & Chen, H. (2024) · Biomaterials Science · doi:10.1039/d4bm00114a · Cited by 17 · see citing works

Effect of nano-chitosan and nano-doxycycline gel on healing of induced oral ulcer in rat model: histological and immunohistochemical study

Mohammed, E., Aboulkhair, A. G., & Tawifq, M. M. (2021) · Clinical Oral Investigations · doi:10.1007/s00784-021-04293-w · Cited by 16 · see citing works

Chitosan as a potential biomaterial for the management of oral mucositis, a common complication of cancer treatment

Rout, S. R., Kar, B., Pradhan, D., Biswasroy, P., Haldar, J., Rajwar, T. K., Sarangi, M. K., Kumar, V., Ghosh, G., & Rath, G. (2022) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2022.2162544 · Cited by 16 · see citing works

Multi-functional nanogel with cascade catalytic performance for treatment of diabetic oral mucosa ulcer

Zheng, Y., Li, Z., Liu, C., Fan, X., Luo, Z., Li, Z., & Wu, Y. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1194398 · Cited by 16 · see citing works

Temperature responsive hydrogels for biomedical applications

Guleria, S., Chopra, L., & Manikanika (2023) · Materials Today Proceedings · doi:10.1016/j.matpr.2023.05.167 · Cited by 15 · see citing works

Advances in chitosan-based materials for oral ulcer treatment

Zhang, X., Lei, J., Qu, T., & Zhang, X. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124110 · Cited by 13 · see citing works

Branched PCL-Based Thermogelling Copolymers: Controlling Polymer Architecture to Tune Drug Release Profiles

Lin, Q., Ow, V., Boo, Y. J., Teo, V. T. A., Wong, J. H. M., Tan, R. P. T., Xue, K., Lim, J. Y. C., & Loh, X. J. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.864372 · Cited by 13 · see citing works

A self-fused hydrogel for the treatment of glottic insufficiency through outstanding durability, extracellular matrix-inducing bioactivity and function preservation

Zou, C., Hu, J., Lu, D., Li, Q., Jiang, Y., Wang, R., Wang, H., Lei, X., Li‐Ling, J., Yang, H., et al. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.12.006 · Cited by 12 · see citing works

Sustainable Polymeric Biomaterials from Alternative Feedstocks

Lin, Q., Chee, P. L., Pang, J. J. M., Loh, X. J., Kai, D., & Lim, J. Y. C. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c01154 · Cited by 11 · see citing works

Advances in smart stimuli-responsive materials for oral wound healing

Liu, X., Huang, X., Liu, N., Zhu, L., Zhao, S., Tang, S., & Wang, P. (2025) · Frontiers in Chemistry · doi:10.3389/fchem.2025.1725373 · Cited by 11 · see citing works

Wet adhesive hydrogels based on niobium carbide for experimental research of oral mucosal impairment

Chen, J., Ren, J., Wu, Y., Hu, N., Fang, Z., & Zhang, L. (2024) · RSC Advances · doi:10.1039/d4ra01352b · Cited by 10 · see citing works

Machine Learning ‐ Driven Polysaccharide ‐ Based Hydrogels: Intelligent Design and Precision Therapeutics for Oral Wound Repair

Hong, W., Zhang, Q., Lin, L., Zhang, H., Lei, X., Wang, Y., Zhang, D., Jia, Z., Wang, L., Pang, J., et al. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202525950 · Cited by 9 · see citing works

Study on self‐healing gel plugging agent based on non‐covalent bonding interaction for drilling fluid

Qu, Y., Zhou, X., Ren, H., Yuan, Y., Zhang, W., Yang, G., & Zhang, X. (2023) · Journal of Applied Polymer Science · doi:10.1002/app.53874 · Cited by 9 · see citing works

A Polyanionic Tartrate‐containing Temperature‐responsive Hydrogel

Loh, W. W., Huang, M., Goh, L., Lim, C. C., Goh, R. Z. R., Lin, Q., Guo, L., Loh, X. J., & Lim, J. Y. C. (2022) · Chemistry - An Asian Journal · doi:10.1002/asia.202200621 · Cited by 8 · see citing works

From design to Deployment: The innovative role of nanomicelles in targeted ophthalmic therapeutics

Sun, M., Wang, J., Fan, W., Wang, K., Wang, Y., Zhang, J., Ding, S., Zhang, C., Feng, Z., Wang, Y.-G., et al. (2025) · Materials today. Bio · doi:10.1016/j.mtbio.2025.102537 · Cited by 7 · see citing works

Full-Thickness Oral Mucoperiosteal Defects: Challenges and Opportunities

Allen, B. N., Wang, Q., Filali, Y., Worthington, K. S., & Kacmarynski, D. S. F. (2021) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2021.0044 · Cited by 7 · see citing works

Dendronization of chitosan to afford unprecedent thermoresponsiveness and tunable microconfinement

Yao, Y., Shi, X.-X., Zhao, Z., Zhang, A., & Li, W. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb01803b · Cited by 7 · see citing works

Excellent salt- and temperature-resistant chitosan-based flocculants for treating and recycling of saline textile effluents

Jiang, H., Guo, H., Shi, Y., Zhang, L. L., Ahmad, A., Wei, T., & Ran, T. (2026) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2026.119703 · Cited by 4 · see citing works

Platelet-Rich Plasma-Embedded Porous Polycaprolactone Film with a Large Surface Area for Effective Hemostasis

Kim, M. J., Song, Y., Kwon, T. G., Lee, J. H., Chun, S. Y., & Oh, S. H. (2024) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-024-00656-y · Cited by 3 · see citing works

Development and Characterization of a Novel Composite Hydrogel Biomaterial for Improved Mucoperiosteal Wound Repair

Wang, Q., Dunnwald, M., Kacmarynski, D. S. F., & Worthington, K. S. (2024) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.35476 · Cited by 2 · see citing works

An orthogonal analytical platform for determining critical material attributes for in situ formation of thermosensitive hyaluronic acid-poly(N-isopropylacrylamide) copolymers

Bonelli, M., Allémann, É., & Stefano, M. D. (2024) · Polymer · doi:10.1016/j.polymer.2024.127728 · Cited by 2 · see citing works

Recent Advances on Noninvasive Ocular Therapeutic Delivery Strategy Based on Polymeric Formulations

Wu, Y., & Li, Z. (2021) · Therapeutic Delivery · doi:10.4155/tde-2021-0030 · Cited by 2 · see citing works

Evaluating the Effects of Cigarette Smoking and Heated Tobacco Products on the Oral Mucosa and Periodontium in Patients with Hepatit C virus in Armenia: A Pilot Study

Azatyan, V., Yessayan, L., Shmavonyan, M., & Muradyan, A. A. (2026) · THE NEW ARMENIAN MEDICAL JOURNAL · doi:10.56936/18290825-2026.20v.2-56 · Cited by 1 · see citing works

Starch-based bionanocomposite films infused with amoxicillin-loaded CuO nanoparticles and their enhanced antimicrobial activity against AMR pathogens

Thakkar, A., Darji, T., Priyadarshi, G. V., Patel, B., Suhas, V., Patel, A., Khusanov, A., Tashbaev, S., Bagatharia, S., & Patel, A. (2026) · Discover Materials · doi:10.1007/s43939-026-00824-y · Cited by 1 · see citing works

MORPHOLOGICAL FEATURES OF BIOPSY SAMPLES OF THE ORAL MUCOSA IN PATIENTS WITH VIRAL HEPATITIS B AND C

Sahakyan, K., Mkrtchyan, G., Yessayan, L., & Azatyan, V. (2024) · BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY · doi:10.58240/1829006x-2024.2-15 · Cited by 1 · see citing works

Preparation of chitosan/nano-copper sulfide/carrageenan bilayer film and its application in strawberry preservation

Zeng, Y., Xue, Z., Geng, C., & Qiao, C. (2025) · Journal of Polymer Engineering · doi:10.1515/polyeng-2025-0076

Thermosensitive, injectable, biocompatible epigallocatechin gallate liposomes/modified chitosan composite hydrogel for efficient skin repairing

Huang, Z., Wen, W., Huang, S., Yu, Y., Cao, Y., Xiang, H., Xu, D., Xuan, J., Zhang, L., Peng, W., et al. (2026) · Journal of drug targeting · doi:10.1080/1061186x.2026.2623192

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) in children: a case report and literature review

Wang, H., & Zong, J. (2026) · Open Life Sciences · doi:10.1515/biol-2025-1328

Two‐Dimensional Conjugated Metal Organic Frameworks with Dual Metal Catalytic Active Sites Enhance POD Activity for Antibacterial Treatment

YiXuan, L., Li, Q., Chen, Y., Zhang, S., Ding, S., Wang, Y., Liu, Y., Guo, Y., Deng, X., & Guo, S. (2026) · Advanced Science · doi:10.1002/advs.76605

Causal associations between gut microbiota and five common oral lesions: A two-sample Mendelian randomization study

Tang, Y., Yuan, J., & Pan, F. (2026) · Medicine · doi:10.1097/md.0000000000049705

Breaking drug dependency: a self-antioxidant bilayer patch for oral ulcer treatment

Ding, Y., Zeng, Q., Peng, X., Ren, K., Zhang, M., Xu, X., Huang, X., Wu, T., Xie, J., & Li, J. (2026) · Materials Horizons · doi:10.1039/d6mh01021k

Engineering synthetic thermogels

Wang, N., Park, M. H., Yu, L., Lin, Q., Chang, J. J., Goh, R. Z. R., Jeong, B., Ding, J., & Loh, X. J. (2026) · Nature Reviews Methods Primers · doi:10.1038/s43586-026-00529-9

Enhanced healing and antimicrobial efficacy of Chitosan-g-Polyacrylamide in a rat model of gingival ulcers

Zheng, Y., Ke, L., Lu, Y., Zuo, Q., Deng, G., Wang, H., & Zeng, X. (2020) · Frontiers in Chemistry · doi:10.3389/fchem.2020.00273 · Cited by 11 · see citing works

Thermally sensitive gels based on chitosan derivatives for the treatment of oral mucositis

Rossi, S., Marciello, M., Bonferoni, M. C., Ferrari, F., Sandri, G., Dacarro, C., Grisoli, P., & Caramella, C. M. (2009) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2009.10.003 · Cited by 77 · see citing works

Development and Evaluation of In Situ Gel Formation for Treatment of Mouth Ulcer

GURAV, N. H., & Husukale, P. S. (2022) · Turkish Journal of Pharmaceutical Sciences · doi:10.4274/tjps.galenos.2022.25968 · Cited by 16 · see citing works

Advances in chitosan-based materials for oral ulcer treatment

Zhang, X., Lei, J., Qu, T., & Zhang, X. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124110 · Cited by 13 · see citing works

Multi-functional octanoyl glycol chitosan/gallic acid thermogels as hemostatic wound dressings

Shin, S. Y., Kim, S., Le, T. P., Kim, R. E., Park, S. Y., Kim, E. Y., Kwon, Y. J., Pham, H. M., Cho, W. K., Kim, M. K., et al. (2026) · Polymer Testing · doi:10.1016/j.polymertesting.2026.109332