Cited by 977Hair Growth and Disordersdental development and anomaliesSkin and Cellular Biology Research

The DOI matches its Crossref record; 130 of the 131 references it cites were found in a registry or an index.

Molecular Mechanisms Regulating Hair Follicle Development

Open access

Millar, Sarah E.·2002·Journal of Investigative Dermatology

DOI 10.1046/j.0022-202x.2001.01670.x

Open this paper in CoChat — free account Open PDF

Abstract

Clinical conditions causing hair loss, such as androgenetic alopecia, alopecia areata, and scarring alopecia, can be psychologically devastating to individuals and are the target of a multimillion dollar pharmaceutical industry. The importance of the hair follicle in skin biology, however, does not rest solely with its ability to produce hair. Hair follicles are self-renewing and contain reservoirs of multipotent stem cells that are capable of regenerating the epidermis and are thought to be utilized in wound healing. Hair follicles are also the sites of origin of many neoplasias, including some basal cell carcinomas and pilomatricoma. These diseases result from inappropriate activation of signaling pathways that regulate hair follicle morphogenesis. Identification of the signaling molecules and pathways operating in developing and postnatal, cycling, hair follicles is therefore vital to our understanding of pathogenic states in the skin and may ultimately permit the development of novel therapies for skin tumors as well as for hair loss disease. The purpose of this review is to summarize recent progress in our understanding of the molecular mechanisms regulating hair follicle formation, and to discuss ways in which this information may eventually be utilized in the clinic.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1046/j.0022-202x.2001.01670.x

Cites

130 of 130 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
Cotsarelis, G., Sun, T.-T., & Lavker, R. M. (1990) · Cell · doi:10.1016/0092-8674(90)90696-c · Cited by 2,276
MECHANISMS OF WNT SIGNALING IN DEVELOPMENT
Wodarz, A., & Nusse, R. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.59 · Cited by 2,030
Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome
Hahn, H., Wicking, C., Zaphiropoulos, P. G., Gailani, M. R., Shanley, S., Chidambaram, A., Vořechovský, I., Holmberg, E., Undén, A. B., Gillies, S. A., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81268-4 · Cited by 2,018
Human Homolog of patched , a Candidate Gene for the Basal Cell Nevus Syndrome
Johnson, R. L., Rothman, A., Xie, J., Goodrich, L. V., Bare, J. W., Bonifas, J. M., Quinn, A., Myers, R., Cox, D., Epstein, E. H., et al. (1996) · Science · doi:10.1126/science.272.5268.1668 · Cited by 1,856
Controls of Hair Follicle Cycling
Stenn, K. S., & Paus, R. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.449 · Cited by 1,543
HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo
Bitgood, M. J., & McMahon, A. P. (1995) · Developmental Biology · doi:10.1006/dbio.1995.0010 · Cited by 1,370
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G., & Birchmeier, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00336-1 · Cited by 1,352
De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin
Gat, U., DasGupta, R., Degenstein, L., & Fuchs, E. (1998) · Cell · doi:10.1016/s0092-8674(00)81631-1 · Cited by 1,089
Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Taylor, G., Lehrer, M. S., Jensen, P. J., Sun, T.-T., & Lavker, R. M. (2000) · Cell · doi:10.1016/s0092-8674(00)00050-7 · Cited by 1,070
Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K., & Barrandon, Y. (2001) · Cell · doi:10.1016/s0092-8674(01)00208-2 · Cited by 1,043

Show all 131 references

Sorted by citations

Items 601–700 of 977

The Current Status and Future Direction of Extracellular Nano-vesicles in the Alleviation of Skin Disorders
Ghorbani, R., Hosseinzadeh, S., Azari, A., Taghipour, N., Soleimani, M., Rahimpour, A., & Abbaszadeh, H. (2023) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x18666230418121053 · Cited by 12
Regulation of cashmere fineness traits by noncoding RNA in Jiangnan cashmere goats
Wu, C., Xu, Q., Li, J., Qin, C., Tulafu, H., Liu, W., Lu, Q., Zheng, W., & Fu, X. (2023) · BMC Genomics · doi:10.1186/s12864-023-09531-x · Cited by 11
MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata
Wang, J., Ma, Y., Li, T., Li, J., Yang, X., Hua, G., Cai, G., Zhang, H., Liu, Z., Wu, K., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417632 · Cited by 11
The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis
Okada, T., Ishii, Y., Masujin, K., Yasoshima, A., Matsuda, J., Ogura, A., Nakayama, H., Kunieda, T., & Doi, K. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050507 · Cited by 11
Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit during Hair Cycle
Xu, Y., Yang, L., Tian, Y., Xiang, M., Huang, E., & Lian, X. (2008) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.08024 · Cited by 10
Expression of beta-catenin, p63 and CD34 in hair follicles during the course of androgenetic alopecia
Fiurášková, M., Brychtová, S., Kolář, Z., Kučerová, R., & Bienová, M. (2005) · Archives of Dermatological Research · doi:10.1007/s00403-005-0592-6 · Cited by 11
Diseases of the hair
Restrepo, R., & Calonje, E. J. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4160-5649-2.00022-6 · Cited by 11
Activin A‐induced signalling controls hair follicle neogenesis
Seo, C. H., Kwack, M. H., Kim, M., Kim, J. C., & Sung, Y. K. (2016) · Experimental Dermatology · doi:10.1111/exd.13234 · Cited by 11
Skin Cancers and the Contribution of Rho GTPase Signaling Networks to Their Progression
Pecora, A., Laprise, J., Dahmene, M., & Laurin, M. (2021) · Cancers · doi:10.3390/cancers13174362 · Cited by 10
Histology of the Human Hair Follicle
Whiting, D. A. (2008) · Springer eBooks · doi:10.1007/978-3-540-46911-7_7 · Cited by 11
Mathematical model for alopecia areata
Dobréva, A., Paus, R., & Cogan, N. G. (2015) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2015.05.033 · Cited by 11
The multipotency of adult vibrissa follicle stem cells
Amici, A. W., Yamato, M., Okano, T., & Kobayashi, K. (2009) · Differentiation · doi:10.1016/j.diff.2008.10.010 · Cited by 11
Molecular Mechanisms of Hair Follicle Development
Kinde, M. Z., Mekuria, T. A., Gessese, A. T., & Mengistu, B. A. (2024) · The Scientific World JOURNAL · doi:10.1155/tswj/5259055 · Cited by 13
Development of in vitro hair pigmentation model using hair follicle organoids
Tu, S., Kageyama, T., Seo, J., Zhou, Y., & Fukuda, J. (2024) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2024.11.003 · Cited by 11
Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Keerti, A., Madke, B., Keerti, A., Lopez, M. J. C., & Lirio, F. S. (2023) · Cureus · doi:10.7759/cureus.44949 · Cited by 10
Somatotopic organization of central arbors from nociceptive afferents develops independently of their intact peripheral target innervation
Olson, W. P., & Luo, W. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24533 · Cited by 11
TRPS1 mutation detection in Chinese patients with Tricho‐rhino‐phalangeal syndrome and identification of four novel mutations
Wang, C., Xu, Y., Qing, Y., Yao, R., Li, N., Wang, X., Yu, T., & Wang, J. (2020) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.1417 · Cited by 10
Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes
Bak, S., Park, J. M., Oh, J. W., Kim, J. C., Kim, M. K., & Sung, Y. K. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.575382 · Cited by 10
Expression of nucleosomal protein HMGN1 in the cycling mouse hair follicle
Furusawa, T., Ko, J.-H., Birger, Y., & Bustin, M. (2009) · Gene Expression Patterns · doi:10.1016/j.gep.2009.03.002 · Cited by 10
Defining the hair follicle stem cell (Part II)
Myung, P. S., Andl, T., & Ito, M. (2009) · Journal of Cutaneous Pathology · doi:10.1111/j.1600-0560.2009.01412.x · Cited by 10
Downregulation of Foxe1 by HR suppresses Msx1 expression in the hair follicles of HrHpmice
Choi, J.-H., Kim, B.-K., Kim, J.-K., Lee, H., Park, J., & KimYoon, S.-J. (2011) · BMB Reports · doi:10.5483/bmbrep.2011.44.7.478 · Cited by 10
Promotion of hair growth by newly synthesized ceramide mimetic compound
Park, B., Bak, S., Shin, K.-O., Kim, M., Kim, D., Jung, S., Jeong, S., Sung, Y. K., & Kim, H. J. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.07.069 · Cited by 10
Fabrication of Chimeric Hair Follicles for Skin Tissue Engineering
Lalley, A. L., & Boyce, S. T. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9473-1_13 · Cited by 9
GDNF neurotrophic factor signalling determines the fate of dermal fibroblasts in wound‐induced hair neogenesis and skin regeneration
Vishlaghi, N., Rieger, S., McGaughey, V., & Lisse, T. S. (2022) · Experimental Dermatology · doi:10.1111/exd.14526 · Cited by 9
The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Manti, P. G., Darbellay, F., Leleu, M., Coughlan, A. Y., Moret, B., Cuennet, J. G., Droux, F., Stoudmann, M., Mancini, G., Hautier, A., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10102647 · Cited by 10
Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways
Liu, G., Liu, C., Zhang, Y., Sun, H., Yang, L., Bai, L., & Gao, S. (2023) · Animals · doi:10.3390/ani13233742 · Cited by 9
Genetic Differences between Male and Female Pattern Hair Loss in a Korean Population
Lee, J., Choi, J., Ha, J., Kim, Y.-J., Lee, C. H., & Hong, K. (2024) · Life · doi:10.3390/life14080939 · Cited by 9
Cyclic renewal in three ectodermal appendage follicles: Hairs, feathers and teeth
Wu, P., Lei, M., Widelitz, R. B., & Chuong, C. (2025) · Developmental Biology · doi:10.1016/j.ydbio.2025.03.009 · Cited by 9
Alteration in Hair Texture Following Regrowth in Alopecia Areata
Valins, W. (2011) · Archives of Dermatology · doi:10.1001/archdermatol.2011.192 · Cited by 9
Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression
Sun, Y., Nakanishi, M., Sato, F., Oikawa, K., Muragaki, Y., & Zhou, G. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.12.039 · Cited by 9
A simple and rapid model for hair-follicle regeneration in the nude mouse
Su, Y., Miao, Y., Jiang, J.-D., Liu, H., Hu, J. C. Y., & Hu, Z. (2015) · Clinical and Experimental Dermatology · doi:10.1111/ced.12563 · Cited by 9
Thymosin β4 Identified by Transcriptomic Analysis from HF Anagen to Telogen Promotes Proliferation of SHF-DPCs in Albas Cashmere Goat
Dai, B., Hao, F., Xu, T., Zhu, B., Ren, L.-Q., Han, X., & Liu, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072268 · Cited by 9
Skin and Adnexa of the Laboratory Mouse
Sundberg, J. P. (2004) · Elsevier eBooks · doi:10.1016/b978-012336425-8/50065-0 · Cited by 9
The role of CTNNB1 and LEF1 in feather follicles development of Anser cygnoides and Anser anser
Sun, Y., Zhou, Y., Msuthwana, P., Liu, C., Liu, C., Sello, C. T., Song, Y., Feng, Z., Li, S., Yang, W., et al. (2020) · Genes & Genomics · doi:10.1007/s13258-020-00950-8 · Cited by 9
Inhibition of class I HDACs preserves hair follicle inductivity in postnatal dermal cells
Park, M., Jang, S., Chung, J. H., Kwon, O., & Jo, S. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-03508-0 · Cited by 10
Raising hairs
Adams, J. U. (2011) · Nature Biotechnology · doi:10.1038/nbt.1887 · Cited by 9
Body-Hair Transplant for Cicatricial Alopecia
Meyer-González, T., & Bisanga, C. N. (2012) · Actas Dermo-Sifiliográficas · doi:10.1016/j.adengl.2012.03.008 · Cited by 9
Sparse and Wavy Hair: A New Model for Hypoplasia of Hair Follicle and Mammary Glands on Rat Chromosome 17
Kuramoto, T., Morimura, K., Nomoto, T., Namiki, C., Hamada, S., Fukushima, S., Sugimura, T., Serikawa, T., & Ushijima, T. (2005) · Journal of Heredity · doi:10.1093/jhered/esi053 · Cited by 9
Modulation of T-Lymphocyte Proliferation by Exogenous Natural Ceramides and Sphingosylphosphorylcholine
TOKURA, Y., Wakita, H., Seo, N., Furukawa, F., Takigawa, M., & Nishimura, K. (1999) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/sj.jidsp.5640206 · Cited by 9
Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells: An in vitro study
Smetana, K., Dvořánková, B., Lacina, L., Čada, Z., & Vonka, V. (2008) · Oncology Reports · doi:10.3892/or.20.1.75 · Cited by 9
A Preview of Selected Articles
Atkinson, S. P. (2017) · Stem Cells · doi:10.1002/stem.2745 · Cited by 9
Epidermal ET ‐1 signal induces activation of resting hair follicles by upregulating the PI3K / AKT pathway in the dermis
Gao, Y. H., Fan, Z., Xiao, X., Kong, D., Han, J., & Chu, W. (2024) · The FASEB Journal · doi:10.1096/fj.202302207r · Cited by 8
Co-delivery of minoxidil and finasteride via ionic liquid and cyclodextrin-assisted in situ thermosensitive hydrogel for synergistic treatment of androgenic alopecia
Liu, Z., Li, X., Xiong, S., Xiao, T., Jiao, S., Chai, G., & Xu, Y. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.125263 · Cited by 8
Numerical approximation of a 3D mechanochemical interface model for skin patterning
Vilaca, L. M. D. O., Milinkovitch, M. C., & Ruíz-Baier, R. (2019) · Journal of Computational Physics · doi:10.1016/j.jcp.2019.01.023 · Cited by 8
Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression
Castro, A. R., Portinha, C., & Logarinho, E. (2019) · Dermatologic Surgery · doi:10.1097/dss.0000000000001895 · Cited by 8
Effects of Wnt10b on dermal papilla cells via the canonical Wnt/β‐catenin signalling pathway in the Angora rabbit
Bai, L., Gao, S., Sun, H., Zhao, X., Yang, L., Hu, H., Sun, J., & Jiang, W. (2019) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13141 · Cited by 8
Nuclear localization of Meis1 in dermal papilla promotes hair matrix cell proliferation in the anagen phase of hair cycle
Namekata, M., Yamamoto, M., & Goitsuka, R. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.09.060 · Cited by 8
Optimal stimulation toward the dermal papilla lineage can be promoted by combined use of osteogenic and adipogenic inducers
Kazi, T., Niibe, I., Nishikawa, A., & Matsuzaki, T. (2019) · FEBS Open Bio · doi:10.1002/2211-5463.12763 · Cited by 10
PCL-Blended Chitosan Substrates for Patterning the Heterotypic Cell Distribution in an Epithelial and Mesenchymal Coculture System
Li, Y. E., Wang, J., Wang, Y.-H., Shao, H., Young, L.-C., & Young, T. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c00304 · Cited by 8
Regional specific differentiation of integumentary organs: SATB2 is involved in α‐ and β‐keratin gene cluster switching in the chicken
Lin, G., Liang, Y., Wu, P., Chen, C.-K., Lai, Y., Jiang, T., Haung, Y., & Chuong, C. (2021) · Developmental Dynamics · doi:10.1002/dvdy.396 · Cited by 8
Expression of miRNA-1-3p and its target gene in hair follicle cycle development of Liaoning Cashmere goat
Zhang, G., Xu, J., Zhang, Y., Yang, S., & Jiang, H. (2022) · Animal Biotechnology · doi:10.1080/10495398.2022.2058519 · Cited by 8
Transcriptome Analysis Reveals Genes Contributed to Min Pig Villi Hair Follicle in Different Seasons
Tian, M., He, X., Wang, W., Feng, Y., Zhang, D., Li, Z., & Liu, D. (2022) · Veterinary Sciences · doi:10.3390/vetsci9110639 · Cited by 9
Hair Growth-Promoting Effects of Rosehip (Rosa canina L.) Seed Oil in C57BL/6 Mice
Truong, V., & Jeong, W. (2023) · Preventive Nutrition and Food Science · doi:10.3746/pnf.2023.28.4.411 · Cited by 8
Immunohistochemical assessment of E-cadherin and β-catenin in trichofolliculomas and trichoepitheliomas
Bezděková, M., Brychtová, S., Sedlákova, E., Steigerová, J., Hlobílková, A., Bienová, M., Kučerová, R., Brychta, T., Krejci, V., & Kolář, Z. (2007) · Biomedical Papers · doi:10.5507/bp.2007.042 · Cited by 8
Evaluation of the Effect of Plant Mixture Ethanol Extracts Containing Biota orientalis L. Extract on Suppression of Sebum in Cultured Sebocytes and on Stimulation of Growth of Keratinocytes Co-cultured with Hair Papilla Cells
Zeng, H., Gu, L., & Maeda, K. (2017) · Cosmetics · doi:10.3390/cosmetics4030029 · Cited by 8
Vitamin D Receptor gene polymorphisms taq-1 and cdx-1 in female pattern hair loss
Bakry, O., Seleit, I., Badr, E. A. E., & Mabrouk, M. S. (2020) · Indian Journal of Dermatology · doi:10.4103/ijd.ijd_482_18 · Cited by 8
In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model
Kim, J. E., Ahn, B., Lee, H., Hwang, M., Shin, S. H., Lee, S. W., Sung, Y. K., & Lee, J. (2013) · Molecular Imaging · doi:10.2310/7290.2012.00046 · Cited by 8
Transcriptomic analysis reveals differentially expressed genes associated with wool length in rabbit
Zhao, B., Chen, Y., Hao, Y., Yang, N., Wang, M., Mei, M., Wang, J., Qiu, X., & Wu, X. (2018) · Animal Genetics · doi:10.1111/age.12701 · Cited by 8
Anti-Hair Loss Effects of the DP2 Antagonist in Human Follicle Dermal Papilla Cells
Lim, H. W., Joo, H. W., Jeon, C. Y., Lee, Y., Kim, M., Shin, J. U., Kim, J., Kim, S., Lee, S., Lim, D., et al. (2024) · Cosmetics · doi:10.3390/cosmetics11050177 · Cited by 7
The role of lipids in promoting hair growth through HIF-1 signaling pathway
Seo, J., Matsumoto, K., Nanmo, A., Tu, S., Jeong, D., Chun, Y., Yan, L., Kageyama, T., & Fukuda, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-88697-8 · Cited by 7
Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats
Chun-hua, Z., Le, F., Li, S., Sachula, W., Hua, B., Mu, L., Antonini, M., & Sun, H. (2025) · Frontiers in Veterinary Science · doi:10.3389/fvets.2025.1635202 · Cited by 7
Exogenous connective tissue growth factor preserves the hair‐inductive ability of human dermal papilla cells
Zhang, P., Ravuri, S. K., Wang, J., Marra, K. G., Kling, R. R., & Chai, J. (2014) · International Journal of Cosmetic Science · doi:10.1111/ics.12146 · Cited by 7
Gellan gum-based hydrogels support the recreation of the dermal papilla microenvironment
Abreu, C. M., Lago, M. E. L., Pires, J., Reis, R. L., da Silva, L. P., & Marques, A. P. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213437 · Cited by 7
Dermal FOXO3 activity in response to Wnt/β-catenin signaling is required for feather follicle development of goose embryos (Anser cygnoides)
Wang, S., Wang, Y., Hu, X., Zhou, Y., Yang, Z., Hou, J., Liu, F., Liu, Q., Mabrouk, I., Yü, J., et al. (2024) · Poultry Science · doi:10.1016/j.psj.2024.103424 · Cited by 7
Keratin Microspheres as Promising Tool for Targeting Follicular Growth
Bejaoui, M., Heah, W. Y., Mizushima, A. K. O., Nakajima, M., Yamagishi, H., Yamamoto, Y. Y., & Isoda, H. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.3c00956 · Cited by 8
Expression of the β-Catenin Gene in the Skin of Embryonic Geese During Feather Bud Development
Wu, W., Xu, R., Xiao, L., Xu, H., & Gao, G. (2007) · Poultry Science · doi:10.3382/ps.2007-00197 · Cited by 7
Effect of intense pulsed light treatment on human skinin vitro: analysis of immediate effects on dermal papillae and hair follicle stem cells
Larouche, D., Kim, D. H., Ratté, G., Beaumont, C., & Germain, L. (2013) · British Journal of Dermatology · doi:10.1111/bjd.12477 · Cited by 7
Isolation and Functional Assessment of Cutaneous Stem Cells
Doucet, Y., & Owens, D. M. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1785-3_13 · Cited by 7
Transcriptome Analysis of Improved Wool Production in Skin-Specific Transgenic Sheep Overexpressing Ovine β-Catenin
Wang, J., Cui, K., Yang, Z., Li, T., Hua, G., Han, D., Yao, Y., Chen, J., Deng, X., Yang, X., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030620 · Cited by 7
Scalp Micro-Pigmentation via Transcutaneous Implantation of Flexible Tissue Interlocking Biodegradable Microneedles
Lahiji, S. F., Um, D. J., Kim, Y.-S., Jang, J., Yang, H., & Jung, H. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11110549 · Cited by 7
Ectopic cilia in 112 dogs: A multicenter retrospective study
Dulaurent, T., Dulaurent, A., Mathieson, I., Michel, J., Medan, S., Barbry, J., Poinsard, A., Balland, O., Mias, G., Charron, J., et al. (2021) · Veterinary Ophthalmology · doi:10.1111/vop.12947 · Cited by 7
lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions
Zhao, B., Li, J., Liu, M., Hu, S., Yang, N., Liang, S., Zhang, X., Dai, Y., Bao, Z., Chen, Y., et al. (2022) · Cells · doi:10.3390/cells11152443 · Cited by 7
Tracing the developmental origin of tissue stem cells
Morita, R., & Fujiwara, H. (2022) · Development Growth & Differentiation · doi:10.1111/dgd.12816 · Cited by 6
Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia via the suppression of 5α-reductase and knockdown of androgen receptor
Chen, X., Yan, P., Zhang, W., He, X., Jiang, R., Li, Y., Sun, J., & Jiang, J. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1033987 · Cited by 9
Hair follicle morphogenesis and epidermal homeostasis in we/we wal/wal mice with postnatal alopecia
Rippa, A. L., Terskikh, V. V., Nesterova, A. P., Vasiliev, A. V., & Vorotelyak, E. A. (2014) · Histochemistry and Cell Biology · doi:10.1007/s00418-014-1291-1 · Cited by 7
PDGF‐AA‐induced filamentous mitochondria benefit dermal papilla cells in cellular migration
Mifude, C., & Kaseda, K. (2014) · International Journal of Cosmetic Science · doi:10.1111/ics.12190 · Cited by 7
The Hair Follicle Stem Cell Niche: The Bulge and Its Environment
Wang, A. B., Jain, P., & Tumbar, T. (2015) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-319-21705-5_1 · Cited by 7
Trps1-deficient transplanted skin gave rise to a substantial amount of hair: Trps1 is unnecessary for hair development
Zhang, Y., Nakamura, T., Furukawa, F., & Muragaki, Y. (2019) · Dermatology Reports · doi:10.4081/dr.2019.7853 · Cited by 7
Understanding skin morphogenesis across developmental, regenerative and evolutionary levels
Plikus, M. V., & Chuong, C. (2019) · Experimental Dermatology · doi:10.1111/exd.13932 · Cited by 7
Restoration of Immune Privilege in Human Dermal Papillae Controlling Epithelial-Mesenchymal Interactions in Hair Formation
Park, J. M., Jun, M. S., Kim, J.-A., Mali, N. M., Hsi, T., Cho, A., Kim, J. C., Kim, J. Y., Seo, I., Kim, J., et al. (2021) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-021-00392-7 · Cited by 7
Overexpression of MYB in the Skin Induces Alopecia and Epidermal Hyperplasia
Hu, Y., Song, Z., Chen, J., & Caulı́n, C. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.10.013 · Cited by 7
Upending the hair follicle
Morgan, B. A. (2006) · Nature Genetics · doi:10.1038/ng0306-273 · Cited by 7
Increased Rate of Hair Regrowth in Mice with Constitutive Overexpression of Del1
Hsu, G. P., Mathy, J. A., Wang, Z., Xia, W., Sakamoto, G. T., Kundu, R. K., Longaker, M. T., Quertermous, T., & Yang, G. P. (2007) · Journal of Surgical Research · doi:10.1016/j.jss.2007.02.024 · Cited by 7
Structure and Development of the Skin and Cutaneous Appendages
Chu, D. H., & Loomis, C. A. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-3479-7.10061-8 · Cited by 7
Embryogenesis of the Skin
Holbrook, K. A. (2011) · Wiley eBooks · doi:10.1002/9781444345384.ch2 · Cited by 7
Hair Follicle Organoids Using Human iPSC-Derived Ectodermal Precursor Cells for Hair Regenerative Medicine
Kageyama, T., Anakama, R., Hamano, S., Tu, S., Migita, Y., Asaba, T., Nanmo, A., Ishikawa, K., Yan, L., Seo, J., et al. (2026) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01780 · Cited by 6
Wnt/β-Catenin Signaling Pathway Targeting Androgenetic Alopecia: How Far Can We Go Beyond Minoxidil and Finasteride?
Zhi, J., Feng, M., Feng, X., Niu, X., Chen, W., Jiang, X., & Bai, R. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c02108 · Cited by 8
A 4D road map for the formation of hair follicles
Saxena, N., & Rendl, M. (2021) · Nature · doi:10.1038/d41586-021-01482-1 · Cited by 6
Establishment and functional characterization of immortalized rabbit dermal papilla cell lines
Li, J., Zhao, B., Zhang, X., Dai, Y., Yang, N., Bao, Z., Chen, Y., Liu, Y., & Wu, X. (2023) · Animal Biotechnology · doi:10.1080/10495398.2023.2252861 · Cited by 6
High migratory activity of dermal sheath cup cells associated with the clinical efficacy of autologous cell-based therapy for pattern hair loss
Ishimatsu‐Tsuji, Y., Niiyama, S., Irisawa, R., Harada, K., Kishimoto, J., & Tsuboi, R. (2023) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2023.11.003 · Cited by 6
The development of an in vitro human hair follicle organoid with a complexity similar to that in vivo
Marinho, P. A., Jeong, G., Shin, S. H., Kim, S. N., Choi, H., Lee, S. H., Park, B. C., Hong, Y. D., Kim, H.-J., & Park, W.-S. (2024) · Biomedical Materials · doi:10.1088/1748-605x/ad2707 · Cited by 7
The development of hair follicles and nail
Lee, S.-H., Platt, S., Lim, C. H., Ito, M., & Myung, P. S. (2024) · Developmental Biology · doi:10.1016/j.ydbio.2024.05.010 · Cited by 6
Deep Hair Phenomics: Implications in Endocrinology, Development, and Aging
Makkar, J., Flores, J., Matich, M., Duong, T. T., Thompson, S. M., Du, Y., Busch, I., Phan, Q. M., Wáng, Q., Delevich, K. M., et al. (2024) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.08.014 · Cited by 6
The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells
Olczak, A., Pieczonka, T. D., Ławicki, S., Łukaszyk, K., Puławska-Czub, A., Cambier, L., & Kobielak, K. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1424077 · Cited by 8
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis
Li, J., Zhao, B., Yu, Y., Bao, Z., Zheng, F., Cai, J., Chen, Y., & Wu, X. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.139292 · Cited by 6
Antimicrobial peptide lysozyme has the potential to promote mouse hair follicle growth in vitro
Su, Y., Liu, H., Wang, J., Lin, B., Miao, Y., & Hu, Z. (2015) · Acta Histochemica · doi:10.1016/j.acthis.2015.07.005 · Cited by 6
Hair Whorl Direction: The Association with Handedness, Footedness, and Eyedness
Çetkin, M., Bayko, S., & Kutoğlu, T. (2019) · Developmental Neuropsychology · doi:10.1080/87565641.2019.1700419 · Cited by 6
Electrochemically Triggered Assembly of Films: A One‐Pot Morphogen‐Driven Buildup
Rydzek, G., Jierry, L., Parat, A., Thomann, J., Voegel, J., Senger, B., Hemmerlé, J., Ponche, A., Frisch, B., Schaaf, P., et al. (2011) · Angewandte Chemie · doi:10.1002/ange.201007436 · Cited by 6
Extracellular Vesicles Including Exosomes for Hair Follicle Regeneration
Aberdam, É., Riche, A. L., Bordes, S., Closs, B., Park, B.-S., & Aberdam, D. (2022) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-030-98331-4_9 · Cited by 6
Comparative Analysis of mRNA and miRNA Expression between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak
Zhang, X., Bao, P., Zheng, Q., Chu, M., Liang, C., Guo, X., Wu, X., He, M., Pei, C., & Yan, P. (2022) · Cells · doi:10.3390/cells11243985 · Cited by 7

Authors: Millar, S. E.
Affiliations: University of Pennsylvania (US)
Corresponding author: Millar, Sarah E.
ORCID: Millar, Sarah E.
Venue: Journal of Investigative Dermatology
Publisher: Elsevier BV
Published: 2002-02
Volume: 118
Issue: 2
Pages: 216-225
ISSN: 0022-202X (ISSN-L)
DOI: 10.1046/j.0022-202x.2001.01670.x
OpenAlex: W2034432190
Cited by: 967
References: 131
Citations by year: 2026: 27 · 2025: 39 · 2024: 45 · 2023: 51 · 2022: 56 · 2021: 46 · 2020: 57 · 2019: 43 · 2018: 45 · 2017: 40 · 2016: 32 · 2015: 41 · 2014: 43 · 2013: 41 · 2012: 51
FWCI: 8.34
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5052 d)
Locations: Journal of Investigative Dermatology (publishedVersion)
PubMed (publishedVersion)
Funders: National Alopecia Areata Foundation
Topics: Health Sciences › Medicine › Dermatology › Hair Growth and Disorders
Health Sciences › Dentistry › General Dentistry › dental development and anomalies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
Keywords: hair follicle development, hair follicle morphogenesis, hair loss, androgenetic alopecia, alopecia areata, scarring alopecia, hair follicle stem cells, signaling pathways, basal cell carcinoma, pilomatrixoma, skin tumors, epidermal regeneration, wound healing
MeSH terms: Animals, Cell Communication, Cell Division, Embryo, Mammalian, Embryo, Nonmammalian, Embryonic and Fetal Development, Humans, Skin, Signal Transduction, Hair Follicle

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Molecular Mechanisms Regulating Hair Follicle Development

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks