Cited by 977Hair Growth and Disordersdental development and anomaliesSkin and Cellular Biology Research

The DOI matches its Crossref record; 130 of the 131 references it cites were found in a registry or an index.

Molecular Mechanisms Regulating Hair Follicle Development

Open access

Millar, Sarah E.·2002·Journal of Investigative Dermatology

DOI 10.1046/j.0022-202x.2001.01670.x

Open this paper in CoChat — free account Open PDF

Abstract

Clinical conditions causing hair loss, such as androgenetic alopecia, alopecia areata, and scarring alopecia, can be psychologically devastating to individuals and are the target of a multimillion dollar pharmaceutical industry. The importance of the hair follicle in skin biology, however, does not rest solely with its ability to produce hair. Hair follicles are self-renewing and contain reservoirs of multipotent stem cells that are capable of regenerating the epidermis and are thought to be utilized in wound healing. Hair follicles are also the sites of origin of many neoplasias, including some basal cell carcinomas and pilomatricoma. These diseases result from inappropriate activation of signaling pathways that regulate hair follicle morphogenesis. Identification of the signaling molecules and pathways operating in developing and postnatal, cycling, hair follicles is therefore vital to our understanding of pathogenic states in the skin and may ultimately permit the development of novel therapies for skin tumors as well as for hair loss disease. The purpose of this review is to summarize recent progress in our understanding of the molecular mechanisms regulating hair follicle formation, and to discuss ways in which this information may eventually be utilized in the clinic.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1046/j.0022-202x.2001.01670.x

Cites

130 of 130 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
Cotsarelis, G., Sun, T.-T., & Lavker, R. M. (1990) · Cell · doi:10.1016/0092-8674(90)90696-c · Cited by 2,276
MECHANISMS OF WNT SIGNALING IN DEVELOPMENT
Wodarz, A., & Nusse, R. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.59 · Cited by 2,030
Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome
Hahn, H., Wicking, C., Zaphiropoulos, P. G., Gailani, M. R., Shanley, S., Chidambaram, A., Vořechovský, I., Holmberg, E., Undén, A. B., Gillies, S. A., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81268-4 · Cited by 2,018
Human Homolog of patched , a Candidate Gene for the Basal Cell Nevus Syndrome
Johnson, R. L., Rothman, A., Xie, J., Goodrich, L. V., Bare, J. W., Bonifas, J. M., Quinn, A., Myers, R., Cox, D., Epstein, E. H., et al. (1996) · Science · doi:10.1126/science.272.5268.1668 · Cited by 1,856
Controls of Hair Follicle Cycling
Stenn, K. S., & Paus, R. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.449 · Cited by 1,543
HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo
Bitgood, M. J., & McMahon, A. P. (1995) · Developmental Biology · doi:10.1006/dbio.1995.0010 · Cited by 1,370
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G., & Birchmeier, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00336-1 · Cited by 1,352
De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin
Gat, U., DasGupta, R., Degenstein, L., & Fuchs, E. (1998) · Cell · doi:10.1016/s0092-8674(00)81631-1 · Cited by 1,089
Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Taylor, G., Lehrer, M. S., Jensen, P. J., Sun, T.-T., & Lavker, R. M. (2000) · Cell · doi:10.1016/s0092-8674(00)00050-7 · Cited by 1,070
Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K., & Barrandon, Y. (2001) · Cell · doi:10.1016/s0092-8674(01)00208-2 · Cited by 1,043

Show all 131 references

Sorted by citations

Items 301–400 of 977

Lack of Collagen VI Promotes Wound-Induced Hair Growth
Chen, P., Cescon, M., & Bonaldo, P. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.187 · Cited by 46
Dermo‐epidermal interactions in reptilian scales: Speculations on the evolution of scales, feathers, and hairs
Alibardi, L. (2004) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.20028 · Cited by 46
Use of human intra-tissue stem/progenitor cells and induced pluripotent stem cells for hair follicle regeneration
Ohyama, M. (2019) · Inflammation and Regeneration · doi:10.1186/s41232-019-0093-1 · Cited by 46
A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats
Gandolfi, B., Alhaddad, H., Joslin, S. E. K., Khan, R., Filler, S., Brem, G., & Lyons, L. A. (2013) · Scientific Reports · doi:10.1038/srep02000 · Cited by 45
STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction
Legrand, J. M. D., Roy, E., Ellis, J. J., François, M., Brooks, A. J., & Khosrotehrani, K. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.04.014 · Cited by 50
Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin
Tong, T., Kim, N., & Park, T. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129578 · Cited by 45
Hair Morphogenesis in Vitro : Formation of Hair Structures Suitable for Implantation
Qiao, J., Turetsky, A., Kemp, P. D., & Teumer, J. (2008) · Regenerative Medicine · doi:10.2217/17460751.3.5.683 · Cited by 45
Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Li, S., Thangapazham, R. L., Wang, J.-A., Rajesh, S., Kao, T., Sperling, L. C., Moss, J., & Darling, T. N. (2011) · Nature Communications · doi:10.1038/ncomms1236 · Cited by 45
Hedgehog Signaling
NAGASE, T., Nagase, M., Machida, M., & YAMAGISHI, M. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1389.029 · Cited by 45
Overexpression of the calcium sensing receptor accelerates epidermal differentiation and permeability barrier formation in vivo
Turksen, K., & Troy, T. (2003) · Mechanisms of Development · doi:10.1016/s0925-4773(03)00045-5 · Cited by 45
Regeneration of reptilian scales after wounding: neogenesis, regional difference, and molecular modules
Wu, P., Alibardi, L., & Chuong, C. (2014) · Regeneration · doi:10.1002/reg2.9 · Cited by 44
Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation
Baker, C. M., Verstuyf, A., Jensen, K. B., & Watt, F. M. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.04.005 · Cited by 44
Biology of Human Hair: Know Your Hair to Control It
Araújo, R., Fernandes, M. M., Cavaco-Paulo, A. M., & Gomes, A. C. (2010) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2010_88 · Cited by 44
1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair Regeneration
D, N. A. M., Inoue, K., Chikanishi, T., Fujiki, R., Yamamoto, H., D, H. K. M., D, H. E. M., Doi, K., Itami, S., Kato, S., et al. (2012) · Stem Cells Translational Medicine · doi:10.5966/sctm.2012-0032 · Cited by 44
Article Effect and Mechanism of Ganoderma lucidum Polysaccharides on Human Fibroblasts and Skin Wound Healing in Mice
Hu, F., Yan, Y., Wang, C.-W., Liu, Y., Wang, J.-J., Zhou, F., Zeng, Q.-H., Zhou, X., Chen, J., Wang, A., et al. (2018) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-018-3060-9 · Cited by 44
Epithelial Stem Cells in Adult Skin
Tadeu, A. M. B., & Horsley, V. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-416022-4.00004-4 · Cited by 53
Stem cells in embryonic skin development
Forni, M. F., Trombetta-Lima, M., & Sogayar, M. C. (2012) · Biological Research · doi:10.4067/s0716-97602012000300003 · Cited by 46
A graft model for hair development
Qiao, J., Philips, E., & Teumer, J. (2007) · Experimental Dermatology · doi:10.1111/j.1600-0625.2007.00661.x · Cited by 44
Integrated Analysis of the Roles of Long Noncoding RNA and Coding RNA Expression in Sheep (Ovis aries) Skin during Initiation of Secondary Hair Follicle
Yue, Y., Guo, T., Yuan, C., Liu, J., Guo, J., Feng, R., Niu, C., Sun, X., & Yang, B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156890 · Cited by 45
Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration
Negrini, N. C., Volponi, A. A., Higgins, C. A., Sharpe, P. T., & Celiz, A. D. (2021) · Materials Today Bio · doi:10.1016/j.mtbio.2021.100107 · Cited by 44
The intron 5/6 promoter region of the ship1 gene regulates expression in stem/progenitor cells of the mouse embryo
Rohrschneider, L. R., Custodio, J. M., Anderson, T. A., Miller, C. P., & Gu, H. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.04.032 · Cited by 46
Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons
Sasaki, G. H. (2018) · Aesthetic Plastic Surgery · doi:10.1007/s00266-018-1248-1 · Cited by 42
Hypoxia improves hair inductivity of dermal papilla cells via nuclear NADPH oxidase 4‐mediated reactive oxygen species generation'
Zheng, M., Jang, Y., Choi, N., Kim, D. Y., Han, T. W., Yeo, J. H., Lee, J., & Sung, J. ‐. (2019) · British Journal of Dermatology · doi:10.1111/bjd.17706 · Cited by 43
Roles of TGFβ signaling in epidermal/appendage development
Li, A. G., Koster, M. I., & Wang, X. (2003) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(03)00005-4 · Cited by 40
Role of the host stroma in cancer and its therapeutic significance
Jackson, D. G. (2013) · Cancer and Metastasis Reviews · doi:10.1007/s10555-013-9438-4 · Cited by 40
Requirement for Shh and Fox family genes at different stages in sweat gland development
Kunisada, M., Cui, C., Piao, Y., Ko, M. S. H., & Schlessinger, D. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp089 · Cited by 43
Keratin Expression Provides Novel Insight into the Morphogenesis and Function of the Companion Layer in Hair Follicles
Gu, L.-H., & Coulombe, P. A. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700673 · Cited by 41
Parathyroid Hormone Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin
Diamond, A. G., Gonterman, R. M., Anderson, A. L., Menon, K., Offutt, C. D., Weaver, C. H., Philbrick, W. M., & Foley, J. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700338 · Cited by 42
Nothing but skin and bone
Ross, F. P. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28605 · Cited by 43
The vertebrate corneal epithelium: From early specification to constant renewal
Dhouailly, D., Pearton, D. J., & Michon, F. (2014) · Developmental Dynamics · doi:10.1002/dvdy.24179 · Cited by 40
Differential Expression of microRNAs and their Regulatory Networks in Skin Tissue of Liaoning Cashmere Goat during Hair Follicle Cycles
Bai, W. L., Dang, Y. L., Yin, R. H., Jiang, W. Q., Wang, Z. Y., Zhu, Y. B., Wang, S. Q., Zhao, Y. Y., Deng, L., Luo, G. B., et al. (2016) · Animal Biotechnology · doi:10.1080/10495398.2015.1105240 · Cited by 40
Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hh Signaling Pathway
Ma, X., Tian, Y., Song, Y., Shi, J., Xu, J., Xiong, K., Li, J., Xu, W., Zhao, Y., Shuai, J., et al. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.01.012 · Cited by 40
Regional Control of Hairless versus Hair-Bearing Skin by Dkk2
Song, Y., Boncompagni, A. C., Kim, S.-S., Gochnauer, H. R., Zhang, Y., Loots, G. G., Wu, D., Li, Y., Xu, M., & Millar, S. E. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.017 · Cited by 42
Self-citation
Comparative study on seasonal hair follicle cycling by analysis of the transcriptomes from cashmere and milk goats
Zhang, Y., Wu, K., Wang, L., Wang, Z., Han, W., Chen, D., Wei, Y., Su, R., Wang, R., Liu, Z., et al. (2019) · Genomics · doi:10.1016/j.ygeno.2019.02.013 · Cited by 41
The Basic Science of Hair Biology
Breitkopf, T., Leung, G., Yu, M., Wang, E., & McElwee, K. J. (2012) · Dermatologic Clinics · doi:10.1016/j.det.2012.08.006 · Cited by 40
Impaired skin and hair follicle development in Runx2 deficient mice
Glotzer, D. J., Zelzer, E., & Olsen, B. R. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.01.005 · Cited by 41
Fabrication of a 3D hair follicle‐like hydrogel by soft lithography
Pan, J., Chan, S. Y., Common, J., Amini, S., Miserez, A., Lane, E. B., & Kang, L. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34628 · Cited by 40
Expression of MAEG, a novel basement membrane protein, in mouse hair follicle morphogenesis
OSADA, A., Kiyozumi, D., Tsutsui, K., ONO, Y., Weber, C., Sugimoto, N., IMAI, T., Okada, A., & SEKIGUCHI, K. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.04.053 · Cited by 40
Dermal Papilla Cells: From Basic Research to Translational Applications
Zhang, H.-L., Qiu, X.-X., & Liao, X. (2024) · Biology · doi:10.3390/biology13100842 · Cited by 39
Costunolide promotes the proliferation of human hair follicle dermal papilla cells and induces hair growth in C57 BL /6 mice
Kim, Y., Choi, H. C., Nam, G., & Choi, B. Y. (2018) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.12674 · Cited by 39
Gene Delivery to the Hair Follicle
Ohyama, M., & Vogel, J. C. (2003) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1046/j.1087-0024.2003.00810.x · Cited by 39
Salivary gland function in persons with ectodermal dysplasias
Nordgarden, H., Storhaug, K., Lyngstadaas, S. P., & Jensen, J. L. (2003) · European Journal Of Oral Sciences · doi:10.1034/j.1600-0722.2003.00058.x · Cited by 39
A Novel Role of RASSF9 in Maintaining Epidermal Homeostasis
Lee, C.-M., Yang, P., Chen, L., Chen, C., Wu, S., Cheng, H.-Y., & Chang, Y. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017867 · Cited by 38
In vitro hair follicle growth model for drug testing
Kageyama, T., Miyata, H., Seo, J., Nanmo, A., & Fukuda, J. (2023) · Scientific Reports · doi:10.1038/s41598-023-31842-y · Cited by 43
Signaling in Tooth, Hair, and Mammary Placodes
Ahn, Y. (2015) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2014.11.013 · Cited by 37
A bald statement — Current approaches to manipulate miniaturisation focus only on promoting hair growth
Pantelireis, N., & Higgins, C. A. (2018) · Experimental Dermatology · doi:10.1111/exd.13690 · Cited by 38
Skin transcriptome reveals the periodic changes in genes underlying cashmere (ground hair) follicle transition in cashmere goats
Liu, Z., Yang, F., Zhao, M., Mu, Q., Che, T., Xie, Y., Ma, L., Mi, L., Su, R., Zhao, Y., et al. (2020) · BMC Genomics · doi:10.1186/s12864-020-06779-5 · Cited by 39
Analysis of the Temporal Requirement for Eda in Hair and Sweat Gland Development
Cui, C.-Y., Kunisada, M., Esibizione, D., Douglass, E. G., & Schlessinger, D. (2009) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.318 · Cited by 38
Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Owens, P., Bazzi, H., Engelking, E., Han, G., Christiano, A. M., & Wang, X. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.07.020 · Cited by 37
Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma
Watanabe, S., Kuwabara, Y., Suehiro, S., Yamashita, D., Tanaka, M., Tanaka, A., Ohue, S., & Araki, H. (2016) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-016-2167-1 · Cited by 38
Skin and hair: models for exploring organ regeneration
Yu, B., Mukhopadhyay, A., & Wong, C. F. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn086 · Cited by 37
Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
Park, S. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.933370 · Cited by 40
To the Root of the Curl: A Signature of a Recent Selective Sweep Identifies a Mutation That Defines the Cornish Rex Cat Breed
Gandolfi, B., Alhaddad, H., Affolter, V. K., Brockman, J. A., Häggström, J. U., Joslin, S. E. K., Koehne, A. L., Mullikin, J. C., Outerbridge, C. A., Warren, W. C., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067105 · Cited by 40
Human Hair Reconstruction: Close, But Yet So Far
Mohammadi, P., Youssef, K. K., Abbasalizadeh, S., Baharvand, H., & Aghdami, N. (2016) · Stem Cells and Development · doi:10.1089/scd.2016.0137 · Cited by 39
Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions
Yang, M., Song, S., Dong, K., Chen, X., Liu, X., Rouzi, M., Zhao, Q., He, X., Pu, Y., Guan, W., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-13986-w · Cited by 38
Identification and molecular analysis of a lncRNA-HOTAIR transcript from secondary hair follicle of cashmere goat reveal integrated regulatory network with the expression regulated potentially by its promoter methylation
Jiao, Q., Yin, R. H., Zhao, S. J., Wang, Z. Y., Zhu, Y. B., Wang, W., Zheng, Y. Y., Yin, X. B., Guo, D., Wang, S. Q., et al. (2018) · Gene · doi:10.1016/j.gene.2018.11.084 · Cited by 36
Coordinated hedgehog signaling induces new hair follicles in adult skin
Sun, X., Are, A., Annusver, K., Sivan, U., Jacob, T., Dalessandri, T., Joost, S., Füllgrabe, A., Gerling, M., & Kasper, M. (2020) · eLife · doi:10.7554/elife.46756 · Cited by 37
Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways
Kim, B. H., Lee, M. J., Lee, W.-Y., Pyo, J. S., Shin, M., Hwang, G. S., Shin, D.-C., Kim, C.-E., Park, E., & Kang, K. S. (2021) · Biomolecules · doi:10.3390/biom11070976 · Cited by 36
Bioprinting of Hair Follicle Germs for Hair Regenerative Medicine
Nanmo, A., Yan, L., Asaba, T., Wan, L., Kageyama, T., & Fukuda, J. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.06.021 · Cited by 37
Hair physiology and its disorders
McElwee, K. J., & Sinclair, R. D. (2008) · Drug Discovery Today Disease Mechanisms · doi:10.1016/j.ddmec.2008.04.001 · Cited by 38
Activating β‐catenin signaling in CD 133‐positive dermal papilla cells increases hair inductivity
Zhou, L., YANG, K. Y., Xu, M., Andl, T., Millar, S. E., Boyce, S. T., & Zhang, Y. (2016) · FEBS Journal · doi:10.1111/febs.13784 · Cited by 36
Self-citation
Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development
Tripurani, S. K., Wang, Y., Fan, Y., Rahimi, M., Wong, L., Lee, M.-H., Starost, M. F., Rubin, J. S., & Johnson, G. R. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-08-0488 · Cited by 36
Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems
Su, Y., Wen, J., Zhu, J., Xie, Z., Liu, C. X., Ma, C., Zhang, Q., Xu, X., & Wu, X. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1504-6 · Cited by 37
Contact between Dermal Papilla Cells and Dermal Sheath Cells Enhances the Ability of DPCs to Induce Hair Growth
Yamao, M., Inamatsu, M., Ogawa, Y., Toki, H., Okada, T., Toyoshima, K., & Yoshizato, K. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.241 · Cited by 37
Embryonic dermal condensation and adult dermal papilla induce hair follicles in adult glabrous epidermis through different mechanisms
Inamatsu, M., Tochio, T., Makabe, A., Endo, T., Oomizu, S., Kobayashi, E., & Yoshizato, K. (2006) · Development Growth & Differentiation · doi:10.1111/j.1440-169x.2006.00848.x · Cited by 39
The Cell Cycle Regulator Protein 14-3-3σ Is Essential for Hair Follicle Integrity and Epidermal Homeostasis
Hammond, N. L., Headon, D. J., & Dixon, M. J. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.27 · Cited by 36
Chromatin regulators in mammalian epidermis
Frye, M., & Benitah, S. A. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.08.009 · Cited by 36
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients
Qu, R., Gupta, K., Dong, D., Jiang, Y., Landa, B., Saez, C., Strickland, G., Levinsohn, J. L., Weng, P., Taketo, M. M., et al. (2022) · Developmental Cell · doi:10.1016/j.devcel.2022.03.011 · Cited by 36
Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo
Okabe, N., Ozaki‐Kuroda, K., Nakanishi, H., Shimizu, K., & Takai, Y. (2004) · Developmental Dynamics · doi:10.1002/dvdy.20033 · Cited by 35
Stem cells in ectodermal development
Benitah, S. A., & Frye, M. (2012) · Journal of Molecular Medicine · doi:10.1007/s00109-012-0908-x · Cited by 37
Bioengineering the Hair Follicle
Stenn, K. S., Parimoo, S., Zheng, Y., Barrows, T., Boucher, M., & Washenik, K. (2007) · Organogenesis · doi:10.4161/org.3.1.3237 · Cited by 35
Controlling the stem cell niche: right time, right place, right strength
Niemann, C. (2005) · BioEssays · doi:10.1002/bies.20352 · Cited by 35
Fractals in Biology and Medicine
Losa, G. A. (2011) · Encyclopedia of Molecular Cell Biology and Molecular Medicine · doi:10.1002/3527600906.mcb.201100002 · Cited by 35
Canonical Wnts, specifically Wnt-10b, show ability to maintain dermal papilla cells
Ouji, Y., Nakamura‐Uchiyama, F., & Yoshikawa, M. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.07.108 · Cited by 34
Cutaneous Retinoic Acid Levels Determine Hair Follicle Development and Downgrowth*
Okano, J., Lévy, C., Lichti, U., Sun, H.-W., Yuspa, S., Sakai, Y., & Morasso, M. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.397273 · Cited by 33
Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors
Contreras‐Jurado, C., García-Serrano, L., Martínez‐Fernández, M., Ruiz-Llorente, L., Paramio, J. M., & Aranda, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108137 · Cited by 35
Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Wang, W., Wang, H.-L., Long, Y., Li, Z., & Li, J. (2023) · Biomolecules · doi:10.3390/biom14010020 · Cited by 34
Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State
Kandyba, E. E., Hazen, V. M., Kobielak, A., Butler, S. J., & Kobielak, K. (2013) · Stem Cells · doi:10.1002/stem.1548 · Cited by 33
Comparative investigation of coarse and fine wool sheep skin indicates the early regulators for skin and wool diversity
Li, S., Chen, W., Zheng, X., Liu, Z., Yang, G., Hu, X., & Mou, C. (2020) · Gene · doi:10.1016/j.gene.2020.144968 · Cited by 33
Persistence of Mastomys natalensis papillomavirus in multiple organs identifies novel targets for infection
Nafz, J., Köhler, A., Ohnesorge, M., Nindl, I., Stockfleth, E., & Rösl, F. (2007) · Journal of General Virology · doi:10.1099/vir.0.82955-0 · Cited by 33
Innovative Approaches and Advances for Hair Follicle Regeneration
Zheng, W., & Xu, C.-H. (2023) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c00028 · Cited by 32
Exosomes for hair growth and regeneration
Zhou, Y., Seo, J., Tu, S., Nanmo, A., Kageyama, T., & Fukuda, J. (2023) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2023.11.001 · Cited by 43
Cytokine loaded layer-by-layer ultrathin matrices to deliver single dermal papilla cells for spot-by-spot hair follicle regeneration
Lin, B., Wang, J., Miao, Y., Liu, Y., Jiang, W., Fan, Z., Darabi, M.-A., Hu, Z., & Xing, M. M. Q. (2015) · Journal of Materials Chemistry B · doi:10.1039/c5tb02265g · Cited by 32
Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing
Hao, F., Yan, W., Li, X., Wang, H., Wang, Y., Hu, X., Liu, X., Liang, H., & Liu, D. (2018) · International Journal of Biological Sciences · doi:10.7150/ijbs.23890 · Cited by 31
Hairless is a nuclear receptor corepressor essential for skin function
Thompson, C. C. (2009) · Nuclear Receptor Signaling · doi:10.1621/nrs.07010 · Cited by 32
Ectodysplasin regulates pattern formation in the mammalian hair coat
Zhang, M., Brancaccio, A., Weiner, L., Missero, C., & Brissette, J. L. (2003) · genesis · doi:10.1002/gene.10230 · Cited by 32
Comparisons of mouse models for hair follicle reconstitution
Liang, Y., Silva, K. A., Kennedy, V. E., & Sundberg, J. P. (2011) · Experimental Dermatology · doi:10.1111/j.1600-0625.2011.01366.x · Cited by 31
Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling
Bai, X., Lei, M., Shi, J., Yu, Y., Qiu, W., Lai, X., Liu, Y., Tian, Y., Yang, L., Widelitz, R. B., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.147 · Cited by 31
Skin regeneration with all accessory organs following ablation with irreversible electroporation
Golberg, A., Villiger, M., Broelsch, G. F., Quinn, K. P., Albadawi, H., Khan, S. I., Watkins, M. T., Georgakoudi, I., Austen, W. G., Bei, M., et al. (2016) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2374 · Cited by 31
Anatomy and Physiology of Hair
Erdoğan, B. Ç. (2017) · InTech eBooks · doi:10.5772/67269 · Cited by 31
Establishment and characterization of five immortalized human scalp dermal papilla cell lines
Kwack, M. H., Yang, J. M., Won, G. H., Kim, M. K., Kim, J. C., & Sung, Y. K. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.01.058 · Cited by 31
Chest hair micrografts display extended growth in scalp tissue: a case report
Woods, R., & Campbell, A. W. (2004) · British Journal of Plastic Surgery · doi:10.1016/j.bjps.2004.06.008 · Cited by 31
Regenerative Medicine and Hair Loss: How Hair Follicle Culture has Advanced our Understanding of Treatment Options for Androgenetic Alopecia
Higgins, C. A., & Christiano, A. M. (2013) · Regenerative Medicine · doi:10.2217/rme.13.87 · Cited by 31
Patched mutations and hairy skin patches: A new sign in Gorlin syndrome
Wilson, L. C., Ajayi‐Obe, E., Bernhard, B., & Maas, S. M. (2006) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.31374 · Cited by 31
Vitamin D: Role in Skin and Hair
Bikle, D. D. (2005) · Elsevier eBooks · doi:10.1016/b978-012252687-9/50038-3 · Cited by 32
Glycyrrhizin micellar nanocarriers for topical delivery of baicalin to the hair follicles: A targeted approach tailored for alopecia treatment
Zeng, Q., Wang, Z., Zhu, Z., Hu, Y., Wang, Y., Xue, Y., Wu, Y., Guo, Y., Liang, P., Chen, H., et al. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.122109 · Cited by 30
Expression Profiling and Functional Analysis of Circular RNAs in Inner Mongolian Cashmere Goat Hair Follicles
Shang, F., Wang, Y., Ma, R., Di, Z., Wu, Z., Hai, E., Rong, Y., Pan, J., Liang, L., Wang, Z., et al. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.678825 · Cited by 30
Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system
Dong, L., Hao, H., Liu, J., Tong, C., Ti, D., Chen, D., Chen, L., Li, M., Liu, H., Fu, X., et al. (2015) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2046 · Cited by 30
Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells
Wang, A., Arantes, S., Conti, C. J., McArthur, M. J., Aldaz, C. M., & MacLeod, M. C. (2007) · Molecular Carcinogenesis · doi:10.1002/mc.20298 · Cited by 30
CD10 and CD34 in fetal and adult human hair follicles: dynamic changes in their immunohistochemical expression during embryogenesis and hair cycling
Poblet, E., & Jiménez, F. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08741.x · Cited by 30

Authors: Millar, S. E.
Affiliations: University of Pennsylvania (US)
Corresponding author: Millar, Sarah E.
ORCID: Millar, Sarah E.
Venue: Journal of Investigative Dermatology
Publisher: Elsevier BV
Published: 2002-02
Volume: 118
Issue: 2
Pages: 216-225
ISSN: 0022-202X (ISSN-L)
DOI: 10.1046/j.0022-202x.2001.01670.x
OpenAlex: W2034432190
Cited by: 967
References: 131
Citations by year: 2026: 27 · 2025: 39 · 2024: 45 · 2023: 51 · 2022: 56 · 2021: 46 · 2020: 57 · 2019: 43 · 2018: 45 · 2017: 40 · 2016: 32 · 2015: 41 · 2014: 43 · 2013: 41 · 2012: 51
FWCI: 8.34
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5052 d)
Locations: Journal of Investigative Dermatology (publishedVersion)
PubMed (publishedVersion)
Funders: National Alopecia Areata Foundation
Topics: Health Sciences › Medicine › Dermatology › Hair Growth and Disorders
Health Sciences › Dentistry › General Dentistry › dental development and anomalies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
Keywords: hair follicle development, hair follicle morphogenesis, hair loss, androgenetic alopecia, alopecia areata, scarring alopecia, hair follicle stem cells, signaling pathways, basal cell carcinoma, pilomatrixoma, skin tumors, epidermal regeneration, wound healing
MeSH terms: Animals, Cell Communication, Cell Division, Embryo, Mammalian, Embryo, Nonmammalian, Embryonic and Fetal Development, Humans, Skin, Signal Transduction, Hair Follicle

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Molecular Mechanisms Regulating Hair Follicle Development

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks