Cited by 170Antifungal resistance and susceptibilityFungal Infections and StudiesFungal and yeast genetics research

Phospholipase and protease activities in clinical Candida isolates with reference to the sources of strains: Phospholipase‐ and Protease‐Aktivitat bei klinischen Candida‐Isolaten mit Bezug zur Herkunft der Stämme

Kantarcioǧlu, A. Serda, Yücel, A.·2002·Mycoses

Abstract

The present study was aimed at determining in vitro phospholipase and protease activities in 95 clinical isolates of various Candida species (C. albicans, C. glabrata, C. guilliermondii,C.kefyr, C. krusei, C. lipolytica, C. lusitaniae, C. parapsilosis, C.rugosa and C. tropicalis). 59 (62.1%) of isolates examined were phospholipase positive and 75 (78.9.9%) were protease positive. 56 (93.3%) of C.albicans isolates tested were phospholipase producers - however only a few strains of C. glabrata and C. kefyr behaved in the same way. Protease activity was detected in 57 (95%) of C. albicans strains tested and in a few strains of C. kefyr, C.lipolytica, C. parapsilosis and C. tropicalis- the remaining isolates were negative. 56 strains of C.albicans and 2 strains of C. kefyr tested produced both phospholipase and protease.

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Crossref · 10.1046/j.1439-0507.2002.00727.x

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  • Despite the lack of any secreted proteolytic activity, the C. glabrata genome contains eleven genes (CgYPS1-11) that code for a family of eleven putative GPI-anchored aspartyl proteases known as Yapsins.

    “However, despite the lack of any secreted proteolytic activity [59], the C. glabrata genome contains eleven genes (CgYPS1-11) that code for a family of eleven putative GPI-anchored aspartyl proteases, known as Yapsins [60].”

    From Candida glabrata: A Lot More Than Meets the Eye (2019) · cites this paper as [59]

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Authors
Kantarcioǧlu, A. S., & Yücel, A.
Affiliations
Istanbul University-Cerrahpaşa (TR)
Venue
Mycoses
Publisher
Wiley
Published
2002-06
Volume
45
Issue
5-6
Pages
160-165
ISSN
  • 0027-5557 (ISSN-L)
  • 0933-7407
  • 1439-0507
OpenAlex
W1758436102
Cited by
170
References
33
Citations by year
2026: 3 · 2025: 8 · 2024: 4 · 2023: 4 · 2022: 8 · 2021: 4 · 2020: 4 · 2019: 11 · 2018: 7 · 2017: 5 · 2016: 11 · 2015: 12 · 2014: 8 · 2013: 10 · 2012: 8
FWCI
2.87
Type
journal article
Language
en
Open access
closed
Locations
  • Mycoses (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Keywords
Candida, phospholipase activity, proteolytic activity, clinical isolates, Candida albicans, Candida kefyr, Candida tropicalis, Candida parapsilosis, Candida glabrata, Yarrowia lipolytica, Candida rugosa, Candida krusei, Candida guilliermondii, Candida lusitaniae, Candida species
MeSH terms
Blood, Candida, Candidiasis, Culture Media, Humans, Mouth, Endopeptidases, Phospholipases, Respiratory System, Urine, Virulence

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