The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Cell death induced by the Fas/Fas ligand pathway and its role in pathology
Open accessAbstract
Engagement of the cell death surface receptor Fas by Fas ligand (FasL) results in apoptotic cell death, mediated by caspase activation. Cell death mediated via Fas/FasL interaction is important for homeostasis of cells in the immune system and for maintaining immune‐privileged sites in the body. Killing via the Fas/FasL pathway also constitutes an important pathway of killing for cytotoxic T cells. Fas ligand is induced in activated T cells, resulting in activation‐induced cell death by the Fas/FasL pathway. Recently it has been shown that the Fas receptor can also be up‐regulated following a lesion to the cell, particularly that induced by DNA‐damaging agents. This can then result in killing of the cell by a Fas/FasL‐dependent pathway. Up‐regulation of Fas receptor following DNA damage appears to be p53 dependent.
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Cites
Death Receptors: Signaling and Modulation
Ashkenazi, A., & Dixit, V. M. (1998) · Science · doi:10.1126/science.281.5381.1305 · Cited by 5,866
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p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer Drugs
Müller, M., Wilder, S., Bannasch, D., Israeli, D., Lehlbach, K., Li-Weber, M., Friedman, S. L., Galle, P. R., Stremmel, W., Oren, M., et al. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.11.2033 · Cited by 878
Cited by
The Role of Reactive Oxygen Species in Regulating T Cell-mediated Immunity and Disease
Yarosz, E. L., & Chang, C.-H. (2018) · Immune Network · doi:10.4110/in.2018.18.e14 · Cited by 214
Fu, H., Zhou, D., Zhu, H., Liao, J., Lin, L., Hong, X., Hou, F. F., & Liu, Y. (2019) · Kidney International · doi:10.1016/j.kint.2018.11.043 · Cited by 65
Giri, S., & Lal, G. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.06.006 · Cited by 37
Regulated differentiation of stem cells into an artificial 3D liver as a transplantable source
Chen, F., Wang, H., & Xiao, J. (2020) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2019.0022n · Cited by 8
Metadata
- Authors
- Waring, P., & Müllbacher, A.
- Venue
- Immunology & Cell Biology
- Publisher
- Wiley
- Published
- 1999-08
- Volume
- 77
- Issue
- 4
- Pages
- 312-317
- ISSN
- 0004-945X (ISSN-L)
- 0818-9641
- 1440-1711
- OpenAlex
- W1963673812
- Cited by
- 322
- References
- 4
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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