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Cited by 132Attention Deficit Hyperactivity DisorderPharmaceutical studies and practicesPharmacology and Obesity Treatment

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Slowing of growth in height and weight on stimulants: A characteristic pattern

Poulton, A, Cowell, CT·2003·Journal of Paediatrics and Child Health
DOI 10.1046/j.1440-1754.2003.00107.x
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Abstract

Objective: The aims of the present study were to describe the growth pattern of children starting stimulant medication and to analyse the changes over time in height, weight and height velocity in a cohort of treated patients. Methods: Retrospective review of growth data from files of all newly treated patients with attention‐deficit/hyperactivity disorder in one paediatric practice. Forty‐four boys and seven girls were treated for 6−42 months with either dexam­phetamine (n = 32) or methylphenidate (n = 19). Results: During the first 6 months on stimulant medication 44 children (86%) had a height velocity below the age‐corrected mean and there was weight loss in 39 (76%). The height and weight standard deviation score (SDS) showed a progressive decline that was statistically significant after 6 and 18 months (P < 0.001, paired t‐test). The height velocity was significantly attenuated for the first 30 months (P < 0.01), being lowest during the first 6 months. The mean height deficit during the first 2 years was approximately 1 cm/year. The change in weight SDS was 2.4 times the change in height SDS after 30 months on treatment with a significant correlation (Pearson's correlation coefficient r = 0.88, P < 0.001). Conclusions: Stimulant medication is associated with a decrease in height and weight SDS during the first 6−30 months with a characteristic pattern on the growth chart.

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Research works printed but not linked: 2

  1. NSW Department of Health., 1999, Criteria for the Diagnosis and ­Management of Attention Deficit Hyperactivity Disorder in ­Children and Adolescents.
  2. Vaughan VC, 1969, Textbook of Paediatrics, 15

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Metadata

Authors
Poulton, A., & Cowell, C.
Affiliations
  • Nepean Hospital (AU)
  • Children's Hospital at Westmead (AU)
Corresponding author
Poulton, A
ORCID
Poulton, A
Venue
Journal of Paediatrics and Child Health
Publisher
Wiley
Published
2003-03-28
Volume
39
Issue
3
Pages
180-185
ISSN
  • 1034-4810 (ISSN-L)
  • 1440-1754
DOI
10.1046/j.1440-1754.2003.00107.x
OpenAlex
W2165350357
Cited by
132
References
25
Citations by year
2026: 3 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 7 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 3 · 2015: 10 · 2014: 9 · 2013: 3 · 2012: 7
FWCI
5.10
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Journal of Paediatrics and Child Health (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmaceutical studies and practices
  • Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
Keywords
attention deficit hyperactivity disorder, stimulant medication, d-amphetamine, methylphenidate, growth retardation, height velocity, weight loss, height deficit, children
MeSH terms
Adolescent, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Body Height, Body Weight, Child, Child Development, Child, Preschool, Dextroamphetamine, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Growth Disorders, Humans, Male, Methylphenidate, New South Wales, Probability, Prognosis, Retrospective Studies, Cohort Studies, Incidence, Age Distribution, Sex Distribution, Risk Assessment

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