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Cited by 789Attention Deficit Hyperactivity DisorderBone fractures and treatmentsFamily and Disability Support Research

The effect of ADHD on the life of an individual, their family, and community from preschool to adult life

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Harpin, V A·2005·Archives of Disease in Childhood
DOI 10.1136/adc.2004.059006PMC PMC1765272
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Abstract

Introduction The forearm is the most common fracture location in children, with an increasing incidence. Displaced forearm shaft fractures have traditionally been treated with closed reduction and cast immobilisation. Diaphyseal fractures in children have poor remodelling capacity. Malunion can cause permanent cosmetic and functional disability. Internal fixation with flexible intramedullary nails has gained increasing popularity, without evidence of a better outcome compared with closed reduction and cast immobilisation. Method and analysis This is a multicentre, randomised superiority trial comparing closed reduction and cast immobilisation to flexible intramedullary nails in children aged 7–12 years with >10° of angulation and/or >10 mm of shortening in displaced both bone forearm shaft fractures (AO-paediatric classification: 22D/2.1–5.2). A total of 78 patients with minimum 2 years of expected growth left are randomised in 1:1 ratio to either treatment group. The study has a parallel non-randomised patient preference arm. Both treatments are performed under general anaesthesia. In the cast group a long arm cast is applied for 6 weeks. The flexible intramedullary nail group is immobilised in a collar and cuff sling for 4 weeks. Data are collected at baseline and at each follow-up until 1 year. Primary outcome is (1) PROMIS paediatric upper extremity and (2) forearm pronation-supination range of motion at 1-year follow-up. Secondary outcomes are Quick DASH, Paediatric Pain Questionnaire, Cosmetic Visual Analogue Scale, wrist and elbow range of motion as well as any complications and costs of treatment. We hypothesise that flexible intramedullary nailing results in a superior outcome. Ethics and dissemination We have received ethical board approval (number: 78/1801/2020) and permissions to conduct the study from all five participating university hospitals. Informed consent is obtained from the parent(s). Results will be disseminated in peer-reviewed publications. Trial registration number NCT04664517.

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Authors
Harpin, V. A.
Affiliations
Sheffield Children's Hospital (GB)
Corresponding author
Harpin, V A
ORCID
Harpin, V A
Venue
Archives of Disease in Childhood
Publisher
BMJ
Published
2005-02-01
Volume
90
Issue
suppl_1
Pages
i2-i7
ISSN
  • 0003-9888 (ISSN-L)
  • 1468-2044
DOI
10.1136/adc.2004.059006
PMC
PMC1765272
OpenAlex
W2143445712
Cited by
789
References
13
Citations by year
2026: 22 · 2025: 43 · 2024: 47 · 2023: 54 · 2022: 45 · 2021: 56 · 2020: 51 · 2019: 42 · 2018: 43 · 2017: 56 · 2016: 55 · 2015: 40 · 2014: 45 · 2013: 32 · 2012: 33
FWCI
2.25
Type
journal article
Language
en
Open access
Locations
  • Archives of Disease in Childhood (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Health Sciences › Medicine › Epidemiology › Bone fractures and treatments
  • Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
Keywords
attention deficit hyperactivity disorder, family impact, community impact
MeSH terms
Adolescent, Adult, Age Factors, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Child, Developmental Disabilities, Educational Status, Family Health, Growth Disorders, Humans, Infant, Interpersonal Relations, Quality of Life, Risk Factors, Health Care Costs, Substance-Related Disorders

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