Cited by 156Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology ResearchSmoking Behavior and Cessation

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Localization of nAChR subunit mRNAs in the brain of Macaca mulatta

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Han, Zhi‐Yan, Le Novère, Nicolas, Zoli, Michele, Hill, Joseph A., Champtiaux, Nicolas, Changeux, Jean‐Pierre·2000·European Journal of Neuroscience

DOI 10.1046/j.1460-9568.2000.00262.x

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Abstract

We present here a systematic mapping of nAChR subunit mRNAs in Macaca mulatta brain. A fragment, from the transmembrane segments MIII to MIV of Macaca neuronal nAChR subunits was cloned, and shown to exhibit high identity (around 95%) to the corresponding human subunits. Then, specific oligodeoxynucleotides were synthesized for in situ hybridization experiments. Both alpha4 and beta2 mRNA signals were widely distributed in the brain, being stronger in the thalamus and in the dopaminergic cells of the mesencephalon. Most brain nuclei displayed both alpha4 and beta2 signals with the exception of some basal ganglia regions and the reticular thalamic nucleus which were devoid of alpha4 signal. alpha6 and beta3 mRNA signals were selectively concentrated in the substantia nigra and the medial habenula. The strongest signals for alpha3 or beta4 mRNAs were found in the epithalamus (medial habenula and pineal gland), whereas there were no specific alpha3 or beta4 signals in mesencephalic dopaminergic nuclei. alpha5 and alpha7 mRNA signals were found in several brain areas, including cerebral cortex, thalamus and substantia nigra, although at a lower level than alpha4 and beta2. The distribution of alpha3, alpha4, alpha5, alpha6, alpha7, beta2, beta3 and beta4 subunit mRNAs in the monkey is substantially similar to that observed in rodent brain. Surprisingly, alpha2 mRNA signal was largely distributed in the Macaca brain, at levels comparable with those of alpha4 and beta2. This observation represents the main difference between rodent and Macaca subunit mRNA distribution and suggests that, besides alpha4beta2*, alpha2beta2* nAChRs constitute a main nAChR isoform in primate brain.

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Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium
Séguéla, P., Wadiche, J. I., Dineley‐Miller, K., Dani, J., & Jw, P. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-02-00596.1993 · Cited by 1,471
Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine
Picciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Pich, E. M., Fuxe, K., & Changeux, J.-P. (1998) · Nature · doi:10.1038/34413 · Cited by 1,320
Self-citation
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus
Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., Polymeropoulos, M., Holik, J., Hopkins, J., Hoff, M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.2.587 · Cited by 1,141
A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy
Steinlein, O. K., Mulley, J. C., Propping, P., Wallace, R. H., Phillips, H. A., Sutherland, G. R., Scheffer, I. E., & Berkovic, S. F. (1995) · Nature Genetics · doi:10.1038/ng1095-201 · Cited by 1,134
The Diversity of Neuronal Nicotinic Acetylcholine Receptors
Sargent, P. B. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.002155 · Cited by 1,052
Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
Wada, E., Wada, K., Boulter, J., Deneris, E. S., Heinemann, S., Patrick, J., & Swanson, L. W. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902840212 · Cited by 1,044
Acetylcholine receptor channel imaged in the open state
Unwin, P. N. T. (1995) · Nature · doi:10.1038/373037a0 · Cited by 1,000
Neurobiology of the Caenorhabditis elegans Genome
Bargmann, C. I. (1998) · Science · doi:10.1126/science.282.5396.2028 · Cited by 929
Nicotine activates and desensitizes midbrain dopamine neurons
Pidoplichko, V. I., DeBiasi, M., Williams, J. T., & Dani, J. A. (1997) · Nature · doi:10.1038/37120 · Cited by 769
Nicotinic Receptors in the Development and Modulation of CNS Synapses
Role, L. W., & Berg, D. K. (1996) · Neuron · doi:10.1016/s0896-6273(00)80134-8 · Cited by 762
Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain.
Young, W. S., Bonner, T. I., & Brann, M. R. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.24.9827 · Cited by 748
Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats
Imperato, A., Mulas, A., & Di Chiara, G. (1986) · European Journal of Pharmacology · doi:10.1016/0014-2999(86)90629-1 · Cited by 693
Nicotinic acetylcholine involvement in cognitive function in animals
Levin, E. D., & Simon, B. B. (1998) · Psychopharmacology · doi:10.1007/s002130050667 · Cited by 675
Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
Picciotto, M. R., Zoli, M., Léna, C., Bessis, A., Lallemand, Y., LeNovère, N., Vincent, P., Pich, E. M., Brûlet, P., & Changeux, J.-P. (1995) · Nature · doi:10.1038/374065a0 · Cited by 668
Self-citation
Molecular and cellular aspects of nicotine abuse
Dani, J. A., & Heinemann, S. (1996) · Neuron · doi:10.1016/s0896-6273(00)80112-9 · Cited by 605
Reduced antinociception in mice lacking neuronal nicotinic receptor subunits
Marubio, L. M., Jiménez, M. D. M. A., Cordero‐Erausquin, M., Léna, C., Novère, N. G. L., d’Exaerde, A. D. K., Huchet, M., Damaj, M. I., & Changeux, J. (1999) · Nature · doi:10.1038/19756 · Cited by 538
Self-citation
Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily
Schoepfer, R., Conroy, W. G., Whiting, P. J., Gore, M., & Lindstrom, J. M. (1990) · Neuron · doi:10.1016/0896-6273(90)90031-a · Cited by 473
Nicotinic acetylcholine receptors in health and disease
Lindstrom, J. (1997) · Molecular Neurobiology · doi:10.1007/bf02740634 · Cited by 443
Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells
Novère, N. L., & Changeux, J. (1995) · Journal of Molecular Evolution · doi:10.1007/bf00167110 · Cited by 429
Self-citation
Human neuronal nicotinic receptors
Gotti, C., Fornasari, D., & Clementi, F. (1997) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00034-8 · Cited by 417
A stereotaxic atlas of the brain of the cynomolgus monkey (Macaca fascicularis)
Szabo, J., & Cowan, W. M. (1984) · The Journal of Comparative Neurology · doi:10.1002/cne.902220208 · Cited by 415
Identification of Four Classes of Brain Nicotinic Receptors Using β2 Mutant Mice
Zoli, M., Léna, C., Picciotto, M. R., & Changeux, J. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-12-04461.1998 · Cited by 404
Self-citation
Functional contributions of α5 subunit to neuronal acetylcholine receptor channels
Ramírez-Latorre, J. A., Yu, C., Qu, X., Perin, F., Karlin, A., & Role, L. W. (1996) · Nature · doi:10.1038/380347a0 · Cited by 395
Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes.
Chavez-Noriega, L. E., Crona, J. H., Washburn, M. S., Urrutia, A., Elliott, K. J., & Johnson, E. C. (1997) · PubMed · Cited by 392
Identification of four classes of brain nicotinic receptors using beta2 mutant mice.
Zoli, M., Léna, C., Picciotto, M. R., & Changeux, J. (1998) · PubMed Central · doi:10.1523/jneurosci.18-12-04461.1996 · Cited by 387
Self-citation
Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology
Perry, E. K., Morris, C. M., COURT, J. A., Cheng, A. V., FAIRBAIRN, A. F., McKeith, I. G., Irving, D., Brown, A. J., & Perry, R. H. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00410-7 · Cited by 386
Neuronal Nicotinic Receptor a6 Subunit mRNA is Selectively Concentrated in Catecholaminergic Nuclei of the Rat Brain
Le Novere, N., Zoli, M., & Changeux, J. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01206.x · Cited by 385
Self-citation
Drug Addiction: The Yin and Yang of Hedonic Homeostasis
Koob, G. F. (1996) · Neuron · doi:10.1016/s0896-6273(00)80109-9 · Cited by 347
Common Neural Substrates for the Addictive Properties of Nicotine and Cocaine
Pich, E. M., Pagliusi, S. R., Tessari, M., Talabot‐Ayer, D., van Huijsduijnen, R. H., & Chiamulera, C. (1997) · Science · doi:10.1126/science.275.5296.83 · Cited by 347
Assembly of Human Neuronal Nicotinic Receptor α5 Subunits with α3, β2, and β4 Subunits
Wang, F., Gerzanich, V., Wells, G. B., Anand, R., Peng, X.-D., Keyser, K. T., & Lindstrom, J. M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.30.17656 · Cited by 345
Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems
Zoli, M., Novère, N. G. L., Hill, J. A., & Changeux, J. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-03-01912.1995 · Cited by 337
Self-citation
Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats.
Clarke, P. B., Fu, D. S., Jakubovic, A., & Fibiger, H. C. (1988) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22152-8 · Cited by 318
Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes
Vernallis, A. B., Conroy, W. G., & Berg, D. K. (1993) · Neuron · doi:10.1016/0896-6273(93)90333-m · Cited by 304
The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: β4
Duvoisin, R. M., Deneris, E. S., Patrick, J., & Heinemann, S. (1989) · Neuron · doi:10.1016/0896-6273(89)90207-9 · Cited by 291
The primate serotonergic system: a review of human and animal studies and a report on Macaca fascicularis.
Azmitia, E. C., & Gannon, P. J. (1986) · PubMed · Cited by 290
Neurons Can Maintain Multiple Classes of Nicotinic Acetylcholine Receptors Distinguished by Different Subunit Compositions
Conroy, W. G., & Berg, D. K. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.9.4424 · Cited by 288
Nicotinic Receptor Function in Schizophrenia
Leonard, S. S., Adams, C., Breese, C. R., Adler, L. E., Bickford, P. C., Byerley, W., Coon, H. H., Griffith, J. M., Miller, C., Myles‐Worsley, M., et al. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.3.431 · Cited by 263
Nicotine self-administration in animals and humans: similarities and differences
Rose, J. E., & Corrigall, W. A. (1997) · Psychopharmacology · doi:10.1007/s002130050209 · Cited by 262
The distribution of mRNA encoded by a new member of the neuronal nicotinic acetylcholine receptor gene family (α5) in the rat central nervous system
Wada, E., McKinnon, D. H., Heinemann, S., Patrick, J., & Swanson, L. W. (1990) · Brain Research · doi:10.1016/0006-8993(90)90248-a · Cited by 254
Genetic mapping of a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q
Elmslie, F. (1997) · Human Molecular Genetics · doi:10.1093/hmg/6.8.1329 · Cited by 252
β3: A New Member of Nicotinic Acetylcholine Receptor Gene Family Is Expressed in Brain
Deneris, E. S., Boulter, J., Swanson, L. W., Patrick, J., & Heinemann, S. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83343-9 · Cited by 225
Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit
Hill, J., Zoli, M., Bourgeois, J., & Changeux, J. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-04-01551.1993 · Cited by 220
Self-citation
Homomers of alpha 8 and alpha 7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties.
Gerzanich, V., Anand, R., & Lindstrom, J. M. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09916-x · Cited by 218
Neuronal α-Bungarotoxin Receptors Are α7 Subunit Homomers
Drisdel, R. C., & Green, W. N. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-01-00133.2000 · Cited by 213
The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain
Conroy, W. G., Vernallis, A. B., & Berg, D. K. (1992) · Neuron · doi:10.1016/0896-6273(92)90031-8 · Cited by 208
Increased neurodegeneration during ageing in mice lacking high‐affinity nicotine receptors
Zoli, M., Picciotto, M. R., Ferrari, R., Cocchi, D., & Changeux, J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.5.1235 · Cited by 208
Self-citation
Nicotine and food induced dopamine release in the nucleus accumbens of the rat: Putative role of α7 nicotinic receptors in the ventral tegmental area
Schilström, B., Svensson, H. M., Svensson, T. H., & Nomikos, G. G. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00114-6 · Cited by 207
The α-Bungarotoxin-binding Nicotinic Acetylcholine Receptor from Rat Brain Contains Only the α7 Subunit
Chen, D., & Patrick, J. W. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.38.24024 · Cited by 201
Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system
Mulle, C., Vidal, C., Benoit, P., & Changeux, J. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-08-02588.1991 · Cited by 200
Self-citation
Neurotransmitter-gated ion channels as unconventional allosteric proteins
Galzi, J., & Changeux, J. (1994) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(94)90218-6 · Cited by 195
Self-citation
Gene transcripts for the nicotinic acetylcholine receptor subunit, beta4, are distributed in multiple areas of the rat central nervous system
Dineley‐Miller, K., & Patrick, J. (1992) · Molecular Brain Research · doi:10.1016/0169-328x(92)90244-6 · Cited by 194
Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons
Léna, C., d’Exaerde, A. D. K., Cordero‐Erausquin, M., Novère, N. G. L., Jiménez, M. D. M. A., & Changeux, J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.21.12126 · Cited by 181
Self-citation
Comparative morphology of the substantia nigra and ventral tegmental area in the monkey, cat and rat
POIRIER, L. J., Giguère, M., & Marchand, R. (1983) · Brain Research Bulletin · doi:10.1016/0361-9230(83)90173-9 · Cited by 142
[NdI2(thf)5], the First Crystallographically Authenticated Neodymium(II) Complex
Bochkarev, M. N., Fedushkin, I. L., Sebastian Dechert, B., Fagin, A. A., & Schumann, H. (2001) · Angewandte Chemie International Edition · doi:10.1002/1521-3773(20010903)40:17 · Cited by 136
Distribution of Nicotinic Receptors in the Human Hippocampus and Thalamus
Rubboli, F., COURT, J. A., Sala, C., Morris, C. M., Chini, B., Perry, E. K., & Clementi, F. (1994) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1994.tb00550.x · Cited by 134
Functional α6-Containing Nicotinic Receptors Are Present in Chick Retina
Vailati, S., Hanke, W. R. L., Bejan, A., Barabino, B., Longhi, R., Balestra, B., Moretti, M., Clementi, F., & Gotti, C. (1999) · Molecular Pharmacology · doi:10.1124/mol.56.1.11 · Cited by 111
Ultrastructural Localization of the α4-Subunit of the Neuronal Acetylcholine Nicotinic Receptor in the Rat Substantia Nigra
Arroyo-Jiménez, M. D. M., Bourgeois, J.-P., Marubio, L. M., Le Sourd, A.-M., Ottersen, O. P., Rinvik, E., Fairén, A., & Changeux, J.-P. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-15-06475.1999 · Cited by 110
Self-citation
Expression of Neuronal Nicotinic Acetylcholine Receptor Subunit Genes in the Rat Autonomic Nervous System
Rust, G., Burgunder, J., Lauterburg, T., & Cachelin, A. B. (1994) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1994.tb00290.x · Cited by 109
Postsynaptic nicotinic receptors on dopaminergic neurons in the substantia nigra pars compacta of the rat
Sorenson, E. M., Shiroyama, T., & Kitai, S. T. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00064-5 · Cited by 107
Comparative structure of human neuronal α2–α7 and β2–β4 nicotinic acetylcholine receptor subunits and functional expression of the α2, α3, α4, α7, β2, and β4 subunits
Elliott, K. J., Ellis, S. B., Berckhan, K. J., Urrutia, A., Chavez-Noriega, L. E., Johnson, E. C., Veliçelebi, G., & Harpold, M. M. (1996) · Journal of Molecular Neuroscience · doi:10.1007/bf02736842 · Cited by 101
Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders
Léna, C., & Changeux, J. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80088-8 · Cited by 101
Self-citation
Optically imaged maps of orientation preference in primary visual cortex of cats and ferrets
Rao, S. C., Toth, L. J., & Sur, M. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19971027)387:3 · Cited by 93
Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area
Göldner, F. M., Dineley, K. T., & Patrick, J. W. (1997) · Neuroreport · doi:10.1097/00001756-199708180-00019 · Cited by 91
Age-Related Changes in Neuronal Nicotinic Acetylcholine Receptor Subunit α4 Expression Are Modified by Long-Term Nicotine Administration
Rogers, S. W., Gahring, L. C., Collins, A. C., & Marks, M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-13-04825.1998 · Cited by 91
Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: Localization of α3 subunit mRNA, α-bungarotoxin and nicotine binding sites
Cimino, M., Marini, P., Fornasari, D., Cattabeni, F., & Clementi, F. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90472-e · Cited by 88
Differential expression of the neuronal acetylcholine receptor α2 subunit gene during chick brain development
Daubas, P., Devillers‐Thiéry, A., Geoffroy, B., Martı́nez, S., Bessis, A., & Changeux, J. (1990) · Neuron · doi:10.1016/0896-6273(90)90032-b · Cited by 64
Self-citation
Promoter elements conferring neuron-specific expression of the β2-subunit of the neuronal nicotinic acetylcholine receptor studiedin vitro and in transgenic mice
Bessis, A., Salmon, A., Zoli, M., Novère, N. G. L., Picciotto, M. R., & Changeux, J. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00303-z · Cited by 62
Self-citation
Localization of α7 nicotinic receptor subunit mRNA and α‐bungarotoxin binding sites in developing mouse somatosensory thalamocortical system
Bina, K. G., Guzmán, P., Broide, R. S., Leslie, F. M., Smith, M. A., & O’Dowd, D. K. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903630212 · Cited by 62
The organisation of catecholamine-containing neurons in the brain of the rhesus monkey (Macaca mulatta).
Schofield, S. P. M., & Everitt, B. J. (1981) · PubMed · Cited by 60
Ligand-gated ion channels
Cockcroft, V. B., Osguthorpe, D. J., Barnard, E. A., Friday, A. E., & Lunt, G. G. (1990) · Molecular Neurobiology · doi:10.1007/bf02780338 · Cited by 59
Temporally correlated expression of nAChR genes during development of the mammalian retina
Hoover, F., & Goldman, D. J. (1992) · Experimental Eye Research · doi:10.1016/0014-4835(92)90135-f · Cited by 56
α5 Subunit forms functional α3β4α5 nAChRs in transfected human cells
Fucile, S., Barabino, B., Palma, E., Grassi, F., Limatola, C., Mileo, A. M., Alemà, S., Ballivet, M., & Eusebi, F. (1997) · Neuroreport · doi:10.1097/00001756-199707280-00005 · Cited by 53
Expression of the α3 nicotinic receptor subunit mRNA in aging and Alzheimer's disease
Terzano, S., Court, J. A., Fornasari, D., Griffiths, M., Spurden, D., Lloyd, S. R., Perry, R. H., Perry, E. K., & Clementi, F. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00260-5 · Cited by 51
Functional Properties of Neuronal Nicotinic Acetylcholine Receptor Channels Expressed in Transfected Human Cells
Ragozzino, D., Fucile, S., Giovannelli, A., Grassi, F., Mileo, A. M., Ballivet, M., Alemà, S., & Eusebi, F. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01625.x · Cited by 40
Developmental regulation of multiple nicotinic AChR channel subtypes in embryonic chick habenula neurons: contributions of both theα2 andα4 subunit genes
Brussaard, A. B., Yang, X., Doyle, J. P., Huck, S., & Role, L. W. (1994) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/bf02584027 · Cited by 36
Identification and functional significance of nicotinic cholinergic receptors in the rat pineal gland
Stankov, B. M., Cimino, M., Marini, P., Lucini, V., FRASCHINI, F., & Clementi, F. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90456-u · Cited by 26
Stereotaxic coordinates for the Rhesus monkey thalamus and mesencephalon referencing visual afferents and cytoarchitecture.
Benevento, L. (1975) · PubMed · Cited by 21
Contribution a l'etude de la relation structure-fonction dans la famille des sous-unites des recepteurs nicotiniques de l'acetylcholine
Novère, N. L. (1998) · Cited by 1

Research works printed but not linked: 5

Changeux J.‐P., 1990, Functional architecture and dynamics of the nicotinic acetylcholine receptor: an allosteric ligand‐gated ion channel, Fidia Res. Found. Neurosci. Award, 4, 21
Chavez‐Noriega L., 1997, Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα7 expressed in Xenopus oocytes, J. Pharm. Exp. Ther., 280, 346
Han Z.‐Y., 1999, Cloning of Macacus Rhesus Nachr Subunit Gene Fragments and Localisation of the Transcripts in the Brain. Neuronal Nicotinic Receptors: from Structure to Therapeutics
Paxinos G., 2000, The Rhesus Monkey Brain
Wisden W., 1994, Hybridization Protocols for the Brain

Sorted by citations

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Self-citation
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Matta, S. G., Balfour, D. J., Benowitz, N. L., Boyd, R. T., Buccafusco, J. J., Caggiula, A. R., Craig, C. R., Collins, A. C., Damaj, M. I., Donny, E. C., et al. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0441-0 · Cited by 824
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Taly, A., Corringer, P., Guédin, D., Lestage, P. J., & Changeux, J. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2927 · Cited by 743
Self-citation
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See all 156

Authors: Han, Z., Le Novère, N., Zoli, M., Hill, J. A., Champtiaux, N., & Changeux, J.
Affiliations: Centre National de la Recherche Scientifique (FR)
University of Iowa (US)
Corresponding author: Changeux, Jean‐Pierre
ORCID: Han, Zhi‐Yan
Hill, Joseph A.
Champtiaux, Nicolas
Changeux, Jean‐Pierre
Venue: European Journal of Neuroscience
Publisher: Wiley
Published: 2000-10
Volume: 12
Issue: 10
Pages: 3664-3674
ISSN: 0953-816X (ISSN-L)
1460-9568
DOI: 10.1046/j.1460-9568.2000.00262.x
OpenAlex: W2047331648
Cited by: 156
References: 78
Citations by year: 2026: 2 · 2024: 6 · 2023: 5 · 2022: 3 · 2021: 6 · 2020: 7 · 2019: 4 · 2018: 7 · 2017: 3 · 2016: 4 · 2015: 18 · 2014: 6 · 2013: 9 · 2012: 9
FWCI: 2.17
Type: journal article
Language: en
Open access: green
hdl.handle.net
Licence: cc-by
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 449 d)
Locations: European Journal of Neuroscience (publishedVersion)
PubMed (publishedVersion)
IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
Funders: Fondation Simone et Cino Del Duca
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Keywords: nicotinic acetylcholine receptors, rhesus monkeys, primate brain, alpha2 subunit, alpha4beta2 nAChR, thalamus, substantia nigra, medial habenula, dopaminergic neurons, alpha7 subunit, alpha3 subunit, alpha5 subunit, alpha6 subunit, beta3 subunit, beta4 subunit, mRNA localization
MeSH terms: Animals, Brain, Brain Chemistry, Cloning, Molecular, Cytoplasm, Macaca mulatta, Neurons, Receptors, Nicotinic, RNA, Messenger

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Localization of nAChR subunit mRNAs in the brain of Macaca mulatta

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