Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats

Dopamine release and metabolism in awake rats after systemic neuroleptics as studied by trans-striatal dialysis

Impérato, A., & Chiara, G. D. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-02-00297.1985 · Cited by 310 · see citing works

Ethanol preferentially stimulates dopamine release in the nucleus accumbens of freely moving rats

Chiara, G. D., & Impérato, A. (1985) · European Journal of Pharmacology · doi:10.1016/0014-2999(85)90598-9 · Cited by 287 · see citing works

Pharmacologic characterization of nicotine-induced conditioned place preference

Fudala, P. J., Teoh, K., & Iwamoto, E. T. (1985) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(85)90384-3 · Cited by 190 · see citing works

Preferential Stimulation of Dopamine Release in the Nucleus Accumbens by Opiates, Alcohol, and Barbiturates: Studies with Transcerebral Dialysis in Freely Moving Rats

Chiara, G. D., & Impérato, A. (1986) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1986.tb23629.x · Cited by 177 · see citing works

Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex

Ikemoto, S. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.05.004 · Cited by 1,477 · see citing works

The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking

Ikemoto, S., & Panksepp, J. (1999) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00023-5 · Cited by 1,450 · see citing works

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs.

Pontieri, F. E., Tanda, G., Orzi, F., & Chiara, G. D. (1996) · Nature · doi:10.1038/382255a0 · Cited by 1,073 · see citing works

Neurobiology of addiction

Wise, R. A. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80079-1 · Cited by 1,072 · see citing works

Nucleus accumbens shell and core dopamine: differential role in behavior and addiction

Di Chiara, G. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00286-3 · Cited by 996 · see citing works

Dopamine and drug addiction: the nucleus accumbens shell connection

Di Chiara, G., Bassareo, V., Fenu, S., De Luca, M. A., Spina, L., Cadoni, C., Acquas, E., Carboni, E., Valentini, V., & Lecca, D. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.032 · Cited by 935 · see citing works

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

Corrigall, W. A., Franklin, K. B. J., Coen, K. M., & Clarke, P. B. S. (1992) · Psychopharmacology · doi:10.1007/bf02245149 · Cited by 829 · see citing works

Guidelines on nicotine dose selection for in vivo research

Matta, S. G., Balfour, D. J., Benowitz, N. L., Boyd, R. T., Buccafusco, J. J., Caggiula, A. R., Craig, C. R., Collins, A. C., Damaj, M. I., Donny, E. C., et al. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0441-0 · Cited by 824 · see citing works

Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area

Corrigall, W. A., Coen, K. M., & Adamson, K. L. (1994) · Brain Research · doi:10.1016/0006-8993(94)90401-4 · Cited by 740 · see citing works

Cigarette smoking: implications for psychiatric illness

(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.4.546 · Cited by 723 · see citing works

Long-term potentiation of excitatory inputs to brain reward areas by nicotine

Mansvelder, H. D., & McGehee, D. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)00042-8 · Cited by 720 · see citing works

Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria

Drevets, W. C., Gautier, C., Price, J. C., Kupfer, D. J., Kinahan, P. E., Grace, A. A., Price, J. L., & Mathis, C. A. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01038-6 · Cited by 706 · see citing works

Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas

Mansvelder, H. D., Keath, J. R., & McGehee, D. S. (2002) · Neuron · doi:10.1016/s0896-6273(02)00625-6 · Cited by 701 · see citing works

Drug-activation of brain reward pathways

Wise, R. A. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00063-5 · Cited by 684 · see citing works

Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies

Jasinska, A. J., Stein, E. A., Kaiser, J., Naumer, M. J., & Yalachkov, Y. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.10.013 · Cited by 513 · see citing works

The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity

Benwell, M. E. M., & Balfour, D. J. K. (1992) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1992.tb09067.x · Cited by 426 · see citing works

Nicotine effects on adults with attention-deficit/hyperactivity disorder

Levin, E. D., Conners, C. K., Sparrow, E., Hinton, S. C., Erhardt, D., Meck, W. H., Rose, J. E., & March, J. (1996) · Psychopharmacology · doi:10.1007/bf02246281 · Cited by 415 · see citing works

Mindfulness training for smoking cessation: Results from a randomized controlled trial

Brewer, J. A., Mallik, S., Babuscio, T. A., Nich, C., Johnson, H. E., Deleone, C. M., Minnix-Cotton, C. A., Byrne, S. A., Kober, H., Weinstein, A. J., et al. (2011) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.05.027 · Cited by 383 · see citing works

SR141716, a central cannabinoid (CB1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats

Cohen, C., Perrault, G., Voltz, C., Steinberg, R., & Soubrié, P. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200209000-00018 · Cited by 396 · see citing works

Reward, addiction, withdrawal to nicotine

De Biasi, M., & Dani, J. A. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113734 · Cited by 366 · see citing works

Differential desensitization and distribution of nicotinic acetylcholine receptor subtypes in midbrain dopamine areas

Wooltorton, J. R. A., Pidoplichko, V. I., Broide, R. S., & Dani, J. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03176.2003 · Cited by 363 · see citing works

Nicotine-induced upregulation of nicotinic receptors: Underlying mechanisms and relevance to nicotine addiction

Govind, A. P., Vezina, P., & Green, W. N. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.011 · Cited by 338 · see citing works

Brain nicotinic receptors: structure and regulation, role in learning and reinforcement

Changeux, J.-P., Bertrand, D., Corringer, P.-J., Dehaene, S., Edelstein, S., Léna, C., Le Novère, N., Marubio, L., Picciotto, M., & Zoli, M. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00040-4 · Cited by 322 · see citing works

Neurobiology of the nicotine withdrawal syndrome

Kenny, P. J., & Markou, A. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00651-7 · Cited by 310 · see citing works

Craving to quit: Psychological models and neurobiological mechanisms of mindfulness training as treatment for addictions.

Brewer, J. A., Elwafi, H. M., & Davis, J. H. (2013) · Psychology of Addictive Behaviors · doi:10.1037/a0028490 · Cited by 303 · see citing works

Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement

Chaudhri, N., Caggiula, A. R., Donny, E. C., Palmatier, M. I., Liu, X., & Sved, A. F. (2006) · Psychopharmacology · doi:10.1007/s00213-005-0178-1 · Cited by 271 · see citing works

Nicotine: from molecular mechanisms to behaviour

Wonnacott, S., Sidhpura, N., & Balfour, D. J. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2004.12.002 · Cited by 263 · see citing works

α6-Containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens

Exley, R., Clements, M. A., Hartung, H., McIntosh, J. M., & Cragg, S. J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301617 · Cited by 242 · see citing works

Drug addiction as a disorder of associative learning. Role of nucleus accumbens shell/extended amygdala dopamine

DI CHIARA, G., TANDA, G., BASSAREO, V., PONTIERI, F., ACQUAS, E., FENU, S., CADONI, C., & CARBONI, E. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09283.x · Cited by 242 · see citing works

The putative role of extra-synaptic mesolimbic dopamine in the neurobiology of nicotine dependence

Balfour, D. J. K., Wright, A. E., Benwell, M. E. M., & Birrell, C. E. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00202-3 · Cited by 231 · see citing works

SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade

Acquas, E., Carboni, E., Leone, P., & Di Chiara, G. (1989) · Psychopharmacology · doi:10.1007/bf00442800 · Cited by 207 · see citing works

Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome

Hildebrand, B. E., Nomikos, G. G., Hertel, P., Schilström, B., & Svensson, T. H. (1998) · Brain Research · doi:10.1016/s0006-8993(97)01135-9 · Cited by 200 · see citing works

Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction

Pidoplichko, V. I., Noguchi, J., Areola, O. O., Liang, Y., Peterson, J., Zhang, T., & Dani, J. A. (2004) · Learning & Memory · doi:10.1101/lm.70004 · Cited by 196 · see citing works

Dopamine signaling in the nucleus accumbens of animals self-administering drugs of abuse

Willuhn, I., Wanat, M. J., Clark, J. J., & Phillips, P. E. M. (2010) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2009_27 · Cited by 193 · see citing works

Ventral Striatal Dopamine Release in Response to Smoking a Regular vs a Denicotinized Cigarette

Brody, A. L., Mandelkern, M. A., Olmstead, R. E., Allen-Martinez, Z., Scheibal, D., Abrams, A. L., Costello, M. R., Farahi, J., Saxena, S., Monterosso, J., et al. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.87 · Cited by 183 · see citing works

Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine

Benwell, M. E. M., Balfour, D. J. K., & Birrell, C. E. (1995) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1995.tb13248.x · Cited by 169 · see citing works

Localization of nAChR subunit mRNAs in the brain of Macaca mulatta

Han, Z., Le Novère, N., Zoli, M., Hill, J. A., Champtiaux, N., & Changeux, J. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00262.x · Cited by 156 · see citing works

Primary reinforcing effects of nicotine are triggered from multiple regions both inside and outside the ventral tegmental area

Ikemoto, S., Qin, M., & Liu, Z.-H. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4542-05.2006 · Cited by 151 · see citing works

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works

Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons

Azam, L., Chen, Y., & Leslie, F. M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.11.011 · Cited by 138 · see citing works

Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections

Ferrari, R., Le Novère, N., Picciotto, M. R., Changeux, J. P., & Zoli, M. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2001.02009.x · Cited by 132 · see citing works

PET measures of amphetamine-induced dopamine release in ventral versus dorsal striatum

Drevets, W. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00079-2 · Cited by 122 · see citing works

(S)-(−)-cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner

Dwoskin, L. P., Teng, L., Buxton, S. T., & Crooks, P. A. (1999) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38040-1 · Cited by 120 · see citing works

Common aspects of the action of nicotine and other drugs of abuse

Picciotto, M. R. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00074-x · Cited by 117 · see citing works

Effects of transderman nicotine on mood and sleep in nonsmoking major depresssed patients

Salín-Pascual, R. J., Galicia-Polo, L., Drucker-Colín, R., de la Fuente, J. R., Drucker-Colín, R., & Salín-Pascual, R. J. (1995) · Psychopharmacology · doi:10.1007/bf02246496 · Cited by 113 · see citing works

Ultrastructural Localization of the α4-Subunit of the Neuronal Acetylcholine Nicotinic Receptor in the Rat Substantia Nigra

Arroyo-Jiménez, M. D. M., Bourgeois, J.-P., Marubio, L. M., Le Sourd, A.-M., Ottersen, O. P., Rinvik, E., Fairén, A., & Changeux, J.-P. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-15-06475.1999 · Cited by 110 · see citing works

Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats

Carboni, E., Bortone, L., Giua, C., & Di Chiara, G. (2000) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(99)00064-2 · Cited by 96 · see citing works

Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders

Bacher, I., Wu, B., Shytle, D. R., & George, T. P. (2009) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560903329102 · Cited by 96 · see citing works

Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors

David, V., Besson, M., Changeux, J.-P., Granon, S., & Cazala, P. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.02.003 · Cited by 87 · see citing works

Nicotine and endogenous opioids: neurochemical and pharmacological evidence

Hadjiconstantinou, M., & Neff, N. H. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.11.010 · Cited by 81 · see citing works

Depression and nicotine: preclinical and clinical evidence for common mechanisms

Laje, R. P., Berman, J. A., & Glassman, A. H. (2001) · Current Psychiatry Reports · doi:10.1007/s11920-001-0040-z · Cited by 74 · see citing works

Age dependent nicotinic influences over dopamine neuron synaptic plasticity

Placzek, A. N., Zhang, T. A., & Dani, J. A. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.05.014 · Cited by 61 · see citing works

Addiction‐related neuroadaptations following chronic nicotine exposure

Wills, L., & Kenny, P. J. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15356 · Cited by 61 · see citing works

Chronic nicotine administration in the drinking water affects the striatal dopamine in mice

Pietilä, K., & Ahtee, L. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00235-5 · Cited by 50 · see citing works

Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide11Abbreviations: AEA, anandamide, arachidonyl ethanolamide; PEA, palmitoylethanolamide, N-(2-hydroxyethyl) hexadecamide; FAAH, fatty acid amide hydrolase; CB, cannabinoid; PMSF, phenylmethylsulfonyl fluoride; MAFP, methyl arachidonyl fluorophosphonate; methAEA, arachidonyl-1′-hydroxy-2′-propylamide; and NSAIDs, nonsteroidal anti-inflammatory drugs.

Fowler, C. J., Jonsson, K., & Tiger, G. (2001) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00712-2 · Cited by 129 · see citing works

Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems

PETROCELLIS, L. D., Bisogno, T., Ligresti, A., Bifulco, M., Melck, D. J., & Marzo, V. D. (2002) · Fundamental and Clinical Pharmacology · doi:10.1046/j.1472-8206.2002.00094.x · Cited by 88 · see citing works

Catalytic properties of purified recombinant anandamide amidohydrolase

Ueda, N., Katayama, K., Goparaju, S. K., et al. (1999) · Prostaglandins & Other Lipid Mediators · doi:10.1016/s0090-6980(99)90284-8

Synthesis, Molecular Modeling and Biological Evaluation of Metabolically Stable Analogues of the Endogenous Fatty Acid Amide Palmitoylethanolamide

D’Aloia, A., Arrigoni, F., Tisi, R., Palmioli, A., Ceriani, M., Artusa, V., Airoldi, C., Zampella, G., Costa, B., & Cipolla, L. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239074 · Cited by 7 · see citing works

Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-α nuclear receptorsPreprint

Mazzola, C., Medalie, J., Scherma, M., Panlilio, L. V., Solinas, M., Tanda, G., Drago, F., Cadet, J. L., Goldberg, S. R., & Yaşar, S. (2009) · Learning & Memory · doi:10.1101/lm.1145209 · Cited by 130 · see citing works