Cited by 177Liver Disease and TransplantationGastrointestinal motility and disordersGut microbiota and health

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Effect of cisapride on intestinal bacterial overgrowth and bacterial translocation in cirrhosis

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Pardo, Albert, Bartolí, Ramon, Lorenzo-Zúñiga, Vicente, Planas, Ramon, Viñado, Belén, Riba, Joan, Cabré, Eduard, Santos, Justiniano, Luque, Teresa, Ausina, Vicenç, Gassull, Miguel A.·2000·Hepatology

DOI 10.1053/he.2000.5746

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Abstract

Deranged intestinal motility, which occurs in cirrhosis, may facilitate the development of intestinal bacterial overgrowth (IBO), which can lead to bacterial translocation (BT). To assess the effect of cisapride on IBO and BT in cirrhosis, cirrhotic rats received cisapride or a placebo for 7 days, and measurements of jejunal bacterial content and BT studies were performed. In addition, jejunal fluid from 46 cirrhotic patients was obtained for quantitative bacterial culture. Those patients in whom gram-negative IBO was detected were randomized to receive or not to receive cisapride (20 mg twice per day) for 1 week. Cisapride significantly reduced IBO in cirrhotic rats. In addition, no BT was documented in treated animals, whereas it occurred in 40% in nontreated cirrhotic rats. Total IBO was documented in 23 of 46 cirrhotic patients, which was caused by gram-negative organisms in 10 cases. Orocecal transit time (OCT) significantly decreased after cisapride therapy, and was associated with the abolishment of bacterial overgrowth caused by gram-negative organisms in 4 out of 5 treated patients, whereas it persisted in nontreated cases. Cisapride administration to cirrhotic rats resulted in a reduction of the IBO, which is associated with a marked decrease in BT. On the other hand, cisapride facilitates the abolition of IBO caused by gram-negative organisms in cirrhotic patients.

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Hepatogastroenterology
Chen, L., Li, N., & Ye, H. (2012) · Hepatogastroenterology · doi:10.5754/hge12469 · Cited by 3,208
The interdigestive motor complex of normal subjects and patients with bacterial overgrowth of the small intestine
Vantrappen, G., Janssens, J., Hellemans, J., & Ghoos, Y. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108740 · Cited by 815
Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: Results of a double-blind, placebo-controlled trial
Ginés, P., Rimola, A., Planas, R., Vargas, V., Marco, F., Almela, M., Forne, M., Miranda, M. L., Llach, J., Salmerón, J. M., et al. (1990) · Hepatology · doi:10.1002/hep.1840120416 · Cited by 627
Self-citation
A prospective study of bacterial infections in patients with cirrhosis
Caly, W. R., & Strauss, E. (1993) · Journal of Hepatology · doi:10.1016/s0168-8278(05)80280-6 · Cited by 504
Liver transplantation for small hepatocellular carcinoma: The tumor-node-metastasis classification does not have prognostic power
Llovet, J. M., Bruix, J., Fuster, J., Castells, A., García‐Valdecasas, J. C., Grande, L., França, A. V. C., Brú, C., Navasa, M., Ayuso, M. D. C., et al. (1998) · Hepatology · doi:10.1002/hep.510270616 · Cited by 381
Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage
Soriano, G., Guarner, C., Tomás, A., Villanueva, C., Torras, X., González, D., Sáinz, S., Anguera, A., Cussó, X., Balanzó, J., et al. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91514-5 · Cited by 314
Jejunal microflora in patients with chronic alcohol abuse.
Jc, B., Bode, C., Heidelbach, R., Hk, D., & Ga, M. (1984) · PubMed · Cited by 303
Obstructive jaundice promotes bacterial translocation from the gut
Deitch, E. A., Sittig, K. M., Ma, L., Berg, R. D., & Specian, R. D. (1990) · The American Journal of Surgery · doi:10.1016/s0002-9610(05)80610-5 · Cited by 300
Small Intestine Dysmotility and Bacterial Overgrowth in Cirrhotic Patients With Spontaneous Bacterial Peritonitis
Chang, C., Chen, G., Lien, H., & Yeh, H. (1998) · Hepatology · doi:10.1002/hep.510280504 · Cited by 261
Bacterial translocation to mesenteric lymph nodes is increased in cirrhotic rats with ascites
García–Tsao, G., Lee, F., Barden, G. E., Cartun, R. W., & West, A. B. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90147-7 · Cited by 247

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Research works printed but not linked: 10

Llovet, 1993, Am J Gastroenterol, 88, 388
Runyon, 1995, Hepatology, 21, 1719
Chesta, 1993, Hepatology, 17, 828
Shindo, 1993, Am J Gastroenterol, 88, 2084
Enteric bacterial flora and bacterial overgrowth syndrome. In: eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease 6th ed. Philadelphia: Saunders. 1998;1523-1535.
Flexner, 1895, Johns Hopkins Hosp Bull, 6, 64
Berg, 1992, J Med, 23, 217
Bode, 1993, Z Gastroenterol, 31, 3
Martini, 1956, Clin Sci, 16, 35
McCallum, 1991, Am J Gastroenterol, 86, 135

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Lakshmi, C., Ghoshal, U. C., Kumar, S., Goel, A., Misra, A., Mohindra, S., & Choudhuri, G. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-0826-0 · Cited by 37
Bacterial translocation: clinical implications and prevention
Macintire, D. K., & Bellhorn, T. L. (2002) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/s0195-5616(02)00037-2 · Cited by 37
Small Bowel Transit and Altered Gut Microbiota in Patients With Liver Cirrhosis
Liu, Y., Jin, Y., Li, J., Zhao, L., Li, Z., Xu, J., Zhao, F., Feng, J., Chen, H., Fang, C., et al. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00470 · Cited by 35
Hepatosplanchnic circulation in cirrhosis and sepsis
Prin, M. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i9.2582 · Cited by 35
Spontaneous bacterial peritonitis: a therapeutic update
Strauss, E., & Caly, W. R. (2006) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.4.2.249 · Cited by 33
Electroacupuncture reduces blood glucose by regulating intestinal flora in type 2 diabetic mice
An, J., Wang, L., Song, S., Tian, L., Liu, Q., Mei, M., Li, W., & Liu, S. (2022) · Journal of Diabetes · doi:10.1111/1753-0407.13323 · Cited by 32
Is There a Role for Probiotics in Liver Disease?
Lo, R., Austin, A. S., & Freeman, J. G. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/874768 · Cited by 34
Epidemiological and clinical aspects.
Preux, P., & Odermatt, P. (2005) · HAL · Cited by 32
Bacterial translocation in critical illness
Krentz, T., & Allen, S. J. (2017) · Journal of Small Animal Practice · doi:10.1111/jsap.12626 · Cited by 31
Spontaneous bacterial peritonitis – therapeutic challenges in the era of increasing drug resistance of bacteria
Rostkowska, K., Szymanek-Pasternak, A., & Simon, K. A. (2018) · Clinical and Experimental Hepatology · doi:10.5114/ceh.2018.80123 · Cited by 32
Nitric oxide and the hyperdynamic circulation in cirrhosis: is there a role for selective intestinal decontamination?
Rasaratnam, B., Connelly, N. J., & Chin-Dusting, J. P. F. (2004) · Clinical Science · doi:10.1042/cs20040157 · Cited by 30
Procalcitonin, and cytokines document a dynamic inflammatory state in non-infected cirrhotic patients with ascites
Attar, B. M. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i9.2374 · Cited by 29
Gastrointestinal Motility Disorders and Their Clinical Implications in Cirrhosis
Theocharidou, E., Dhar, A., & Patch, D. (2017) · Gastroenterology Research and Practice · doi:10.1155/2017/8270310 · Cited by 29
Laboratory diagnostics of spontaneous bacterial peritonitis
Lippi, G., Danese, E., Cervellin, G., & Montagnana, M. (2014) · Clinica Chimica Acta · doi:10.1016/j.cca.2014.01.023 · Cited by 29
Ascites and spontaneous bacterial peritonitis in patients with liver cirrhosis
van Erpecum, K. J. (2006) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520600664342 · Cited by 28
Proton pump inhibitors use and risk of developing spontaneous bacterial peritonitis in cirrhotic patients: A systematic review and meta-analysis
Alhumaid, S., Mutair, A. S. A., Alawi, Z. A., Zaidi, A. R. Z., Rabaan, A. A., Elhazmi, A., & Al‐Omari, A. (2021) · Gut Pathogens · doi:10.1186/s13099-021-00414-8 · Cited by 27
Influence of proton pump inhibitors in the development of spontaneous bacterial peritonitis
Miozzo, S. A. D. S., John, J. A., da Silva, M. C. A., Dossin, I. D. A., Tovo, C. V., & de Mattos, Â. A. (2017) · World Journal of Hepatology · doi:10.4254/wjh.v9.i35.1278 · Cited by 27
Gut Microbiota, Peroxisome Proliferator-Activated Receptors, and Hepatocellular Carcinoma
Yu, Q., Wu, L., Ji, J., Feng, J., Dai, W., Li, J., Wu, J., & Guo, C. (2020) · Journal of Hepatocellular Carcinoma · doi:10.2147/jhc.s277870 · Cited by 27
Intestinal barrier dysfunction in developing liver cirrhosis: An in vivo analysis of bacterial translocation
Palma, P., Mihaljevic, N., Hasenberg, T., Keese, M. A., & Koeppel, T. A. (2007) · Hepatology Research · doi:10.1111/j.1872-034x.2007.00004.x · Cited by 26
Ascites and spontaneous bacterial peritonitis: Recommendations from two United States centers
Al‐Osaimi, A. M. S., Sundaram, V., & Manne, V. (2014) · Saudi Journal of Gastroenterology · doi:10.4103/1319-3767.141686 · Cited by 26
Novel prevention strategies for bacterial infections in cirrhosis
Yan, K. G., & García–Tsao, G. (2016) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2016.1145663 · Cited by 26
Why do bacteria reach ascitic fluid?
Sola, R. L., & Soriano, G. (2002) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200204000-00002 · Cited by 24

Authors: Pardo, A., Bartolí, R., Lorenzo-Zúñiga, V., Planas, R., Viñado, B., Riba, J., Cabré, E., Santos, J., Luque, T., Ausina, V., & Gassull, M. A.
Affiliations: Hospital Universitari Germans Trias i Pujol (ES)
ORCID: Pardo, Albert
Viñado, Belén
Cabré, Eduard
Ausina, Vicenç
Venue: Hepatology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2000-04
Volume: 31
Issue: 4
Pages: 858-863
ISSN: 0270-9139 (ISSN-L)
DOI: 10.1053/he.2000.5746
OpenAlex: W2013027212
Cited by: 177
References: 42
Citations by year: 2026: 2 · 2025: 3 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 2 · 2020: 3 · 2019: 9 · 2018: 6 · 2017: 7 · 2016: 10 · 2015: 8 · 2014: 12 · 2013: 2 · 2012: 7
FWCI: 5.83
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 5631 d)
Locations: Hepatology (publishedVersion)
PubMed (publishedVersion)
Funders: American Gastroenterological Association
Topics: Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: cisapride, intestinal bacterial overgrowth, bacterial translocation, liver cirrhosis, intestinal motility, Gram-negative bacteria, orocecal transit time
MeSH terms: Adolescent, Adult, Aged, Animals, Bacteria, Female, Gastrointestinal Agents, Humans, Intestines, Liver Cirrhosis, Liver Cirrhosis, Experimental, Male, Middle Aged, Pilot Projects, Rats, Sprague-Dawley, Bacterial Translocation, Cisapride, Rats

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Effect of cisapride on intestinal bacterial overgrowth and bacterial translocation in cirrhosis

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