The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis
Open accessAbstract
Background & aims Several case series have reported the effects of fecal microbiota transplantation (FMT) for ulcerative colitis (UC). We assessed the efficacy and safety of FMT for patients with UC in a double-blind randomized trial.Methods Patients with mild to moderately active UC (n = 50) were assigned to groups that underwent FMT with feces from healthy donors or were given autologous fecal microbiota (control); each transplant was administered via nasoduodenal tube at the start of the study and 3 weeks later. The study was performed at the Academic Medical Center in Amsterdam from June 2011 through May 2014. The composite primary end point was clinical remission (simple clinical colitis activity index scores ≤2) combined with ≥1-point decrease in the Mayo endoscopic score at week 12. Secondary end points were safety and microbiota composition by phylogenetic microarray in fecal samples.Results Thirty-seven patients completed the primary end point assessment. In the intention-to-treat analysis, 7 of 23 patients who received fecal transplants from healthy donors (30.4%) and 5 of 25 controls (20.0%) achieved the primary end point (P = .51). In the per-protocol analysis, 7 of 17 patients who received fecal transplants from healthy donors (41.2%) and 5 of 20 controls (25.0%) achieved the primary end point (P = .29). Serious adverse events occurred in 4 patients (2 in the FMT group), but these were not considered to be related to the FMT. At 12 weeks, the microbiota of responders in the FMT group was similar to that of their healthy donors; remission was associated with proportions of Clostridium clusters IV and XIVa.Conclusions In this phase 2 trial, there was no statistically significant difference in clinical and endoscopic remission between patients with UC who received fecal transplants from healthy donors and those who received their own fecal microbiota, which may be due to limited numbers. However, the microbiota of responders had distinct features from that of nonresponders, warranting further study. ClinicalTrials.gov Number: NCT01650038.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Finally, in two randomized controlled trials of UC patients, FMT responders showed a higher similarity to their donors than nonresponders. 61,62”
From Key determinants of success in fecal microbiota transplantation: From microbiome to clinic (2023) · cites this paper as [61]
In the citing paper
“One trial, in which two faecal transplants were given via the upper GI route, showed no difference in clinical or endoscopic remission between the faecal transplant group and the control group (given autologous stool).76”
From The gut microbiota and host health: a new clinical frontier (2016) · cites this paper as [76]
In the citing paper
“Since that meta-analysis, two randomised controlled trials in UC show discrepant results.”
From The gut microbiota and host health: a new clinical frontier (2016) · cites this paper as [76]
In the citing paper
“Remission (full Mayo score <3 and complete mucosal healing) was achieved in 24% of patients after FMT and 5% with placebo; stool from patients receiving FMT had greater microbial diversity than that of patients given placebo.”
From Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook (2015) · cites this paper as [77]
In the citing paper
“In the study by Moayyedi et. al, seventy-five patients with active UC were randomized to a weekly FMT or water enema for 6 weeks, and there was a statistically significant difference in remission, the primary outcome, between the two groups.”
From Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook (2015) · cites this paper as [77]
In the citing paper
“However, some researchers did not find significant differences in the efficacy of FMT, which may be related to the number and cycle of enemas, preparation process, and limited numbers (147, 148).”
From Stress triggers flare of inflammatory bowel disease in children and adults (2019) · cites this paper as [148]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482
Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis
Rutgeerts, P. J., Sandborn, W. J., Feagan, B. G., Reinisch, W., Olson, A. D., Johanns, J., Travers, S., Rachmilewitz, D., Hanauer, S. B., Lichtenstein, G. R., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050516 · Cited by 3,910
Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile
van Nood, E., Vrieze, A., Nieuwdorp, M., Fuentes, S., Zoetendal, E. G., de Vos, W. M., Visser, C. E., Kuijper, E. J., Bartelsman, J. F. W. M., Tijssen, J. G. P., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1205037 · Cited by 3,708
Self-citationCoated Oral 5-Aminosalicylic Acid Therapy for Mildly to Moderately Active Ulcerative Colitis
Schroeder, K. W., Tremaine, W. J., & Ilstrup, D. M. (1987) · New England Journal of Medicine · doi:10.1056/nejm198712243172603 · Cited by 3,037
Vrieze, A., Van Nood, E., Holleman, F., Salojärvi, J., Kootte, R. S., Bartelsman, J. F. W. M., Dallinga–Thie, G. M., Ackermans, M. T., Serlie, M. J., Oozeer, R., et al. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.06.031 · Cited by 2,913
Self-citationVedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
Feagan, B. G., Rutgeerts, P. J., Sands, B. E., Hanauer, S. B., Colombel, J., Sandborn, W. J., Assche, G. V., Axler, J. L., Kim, H. J., Danese, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1215734 · Cited by 2,892
Classification of Inflammatory Bowel Disease
Lennard‐Jones, J. E. (1989) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365528909091339 · Cited by 2,022
Canoco Reference Manual and User’s Guide: Software for Ordination (version 5.0)
ter Braak, C. J. F., & Šmilauer, P. (2012) · Cited by 1,898
The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead
Kostic, A. D., Xavier, R. J., & Gevers, D. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.02.009 · Cited by 1,789
Claesson, M. J., O’Sullivan, Ó., Wang, Q., Nikkilä, J., Marchesi, J. R., Smidt, H., de Vos, W. M., Ross, R. P., & O’Toole, P. W. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006669 · Cited by 900
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–200 of 922
Host-microbial Cross-talk in Inflammatory Bowel Disease
Nagao‐Kitamoto, H., & Kamada, N. (2017) · Immune Network · doi:10.4110/in.2017.17.1.1 · Cited by 185
Links Between Inflammatory Bowel Disease and Chronic Obstructive Pulmonary Disease
Raftery, A. L., Tsantikos, E., Harris, N. L., & Hibbs, M. L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02144 · Cited by 179
Ulcerative colitis: molecular insights and intervention therapy
Liang, Y., Li, Y., Lee, C., Yu, Z., Chen, C., & Liang, C. (2024) · Molecular Biomedicine · doi:10.1186/s43556-024-00207-w · Cited by 192
New Therapeutics for Ulcerative Colitis
Hirten, R. P., & Sands, B. E. (2021) · Annual Review of Medicine · doi:10.1146/annurev-med-052919-120048 · Cited by 177
Review article: the gut microbiome in inflammatory bowel disease—avenues for microbial management
Mcilroy, J. R., Ianiro, G., Mukhopadhya, I., Hansen, R., & Hold, G. L. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14384 · Cited by 178
HIV and the Gut Microbiota: Composition, Consequences, and Avenues for Amelioration
Vujkovic-Cvijin, I., & Somsouk, M. (2019) · Current HIV/AIDS Reports · doi:10.1007/s11904-019-00441-w · Cited by 180
Kandpal, M., Indari, O., Baral, B., Jakhmola, S., Tiwari, D., Bhandari, V., Pandey, R. K., Bala, K., Sonawane, A., & Jha, H. C. (2022) · Metabolites · doi:10.3390/metabo12111064 · Cited by 177
Stress triggers flare of inflammatory bowel disease in children and adults
Sun, Y., Li, L., Xie, R., Wang, B., Jiang, K., & Cao, H. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00432 · Cited by 171
New treatment options for inflammatory bowel diseases
Verstockt, B., Ferrante, M., Vermeire, S., & Assche, G. V. (2018) · Journal of Gastroenterology · doi:10.1007/s00535-018-1449-z · Cited by 169
Lima, S. F., Gogokhia, L., Viladomiu, M., Chou, L., Putzel, G., Jin, W., Pires, S., Guo, C., Gerardin, Y., Crawford, C. V., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.09.061 · Cited by 176
Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome
Lee, Y., Kamada, N., & Moon, J. J. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114021 · Cited by 169
Fecal Microbiota Transplantation as New Therapeutic Avenue for Human Diseases
Biazzo, M., & Deidda, G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11144119 · Cited by 172
Fecal microbiota transplantation beyond Clostridioides difficile infections
Wortelboer, K., Nieuwdorp, M., & Herrema, H. (2019) · eBioMedicine · doi:10.1016/j.ebiom.2019.05.066 · Cited by 163
Khanna, S., Vázquez‐Baeza, Y., González, A., Weiss, S. J., Schmidt, B. A., Pedrogo, D. A. M., Rainey, J. F., Kammer, P. P., Nelson, H., Sadowsky, M. J., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0269-3 · Cited by 163
Keller, J. J., Ooijevaar, R. E., Hvas, C. L., Terveer, E. M., Lieberknecht-Jouy, S. C., Högenauer, C., Arkkila, P. E. T., Sokol, H., Gridnyev, O., Mégraud, F., et al. (2020) · United European Gastroenterology Journal · doi:10.1177/2050640620967898 · Cited by 168
Self-citationGreen, J. E., Davis, J. A., Berk, M., Hair, C., Loughman, A., Castle, D. J., Athan, E., Nierenberg, A. A., Cryan, J. F., Jacka, F. N., et al. (2020) · Gut Microbes · doi:10.1080/19490976.2020.1854640 · Cited by 163
Current understanding of the gut microbiota shaping mechanisms
Chang, C., & Kao, C. (2019) · Journal of Biomedical Science · doi:10.1186/s12929-019-0554-5 · Cited by 166
Fecal transplantation for treatment of inflammatory bowel disease
Imdad, A., Nicholson, M. R., Tanner‐Smith, E. E., Zackular, J. P., Gomez-Duarte, O. G., Beaulieu, D. B., & Acra, S. A. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012774 · Cited by 160
Microbiome therapeutics: exploring the present scenario and challenges
Yadav, M., & Chauhan, N. S. (2021) · Gastroenterology report · doi:10.1093/gastro/goab046 · Cited by 164
Recipient factors in faecal microbiota transplantation: one stool does not fit all
Danne, C., Rolhion, N., & Sokol, H. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00441-5 · Cited by 154
Bacteroidetes Species Are Correlated with Disease Activity in Ulcerative Colitis
Nomura, K., Ishikawa, D., Okahara, K., Ito, S., Haga, K., Takahashi, M., Arakawa, A., Shibuya, T., Osada, T., Kuwahara-Arai, K., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10081749 · Cited by 150
Putignani, L., CHIERICO, F. D., Vernocchi, P., Cicala, M., Cucchiara, S., & Dallapiccola, B. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000602 · Cited by 153
Sood, A., Mahajan, R., Singh, A., Midha, V., Mehta, V., Narang, V., Singh, T., & Pannu, A. S. (2019) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjz060 · Cited by 150
Microbiota and mucosal defense in IBD: an update
Stange, E. F., & Schroeder, B. O. (2019) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2019.1671822 · Cited by 154
Hiippala, K., Kainulainen, V., Suutarinen, M., Heini, T., Bowers, J. R., Jasso‐Selles, D. E., Lemmer, D., Valentine, M., Barnes, R., Engelthaler, D. M., et al. (2020) · Nutrients · doi:10.3390/nu12040935 · Cited by 148
Abdollahi‐Roodsaz, S., Abramson, S. B., & Scher, J. U. (2016) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2016.68 · Cited by 142
The gut microbiota and inflammatory bowel diseases
Miyoshi, J., & Chang, E. B. (2016) · Translational research · doi:10.1016/j.trsl.2016.06.002 · Cited by 151
Hui, W., Li, T., Liu, W., Zhou, C., & Gao, F. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210016 · Cited by 140
RetractedTreatment Algorithm for Mild and Moderate-to-Severe Ulcerative Colitis: An Update
Burri, E., Maillard, M. H., Schoepfer, A. M., Seibold, F., Assche, G. V., Rivière, P., Laharie, D., Manz, M., & on behalf of the Swiss IBDnet, A. O. W. G. O. T. S. S. O. G. (2020) · Digestion · doi:10.1159/000504092 · Cited by 140
Ianiro, G., Rossi, E., Thomas, A. M., Schinzari, G., Masucci, L., Quaranta, G., Settanni, C. R., Lopetuso, L. R., Armanini, F., Blanco‐Míguez, A., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18127-y · Cited by 139
Wang, R., Cao, S., Bashir, M. E. H., Hesser, L. A., Su, Y., Hong, S. M. C., Thompson, A., Culleen, E., Sabados, M., Dylla, N. P., et al. (2022) · Nature Biomedical Engineering · doi:10.1038/s41551-022-00972-5 · Cited by 140
Long-Term Safety and Efficacy of Fecal Microbiota Transplant in Active Ulcerative Colitis
Ding, X. L., Li, Q., Li, P., Zhang, T., Cui, B., Ji, G., Lü, X., & Zhang, F. (2019) · Drug Safety · doi:10.1007/s40264-019-00809-2 · Cited by 139
Ishikawa, D., Sasaki, T., Osada, T., Kuwahara‐Arai, K., Haga, K., Shibuya, T., Hiramatsu, K., & Watanabe, S. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000975 · Cited by 138
Challenges in fecal donor selection and screening for fecal microbiota transplantation: A review
Woodworth, M. H., Carpentieri, C., Sitchenko, K. L., & Kraft, C. S. (2017) · Gut Microbes · doi:10.1080/19490976.2017.1286006 · Cited by 136
Goyal, A., Yeh, A., Bush, B. R., Firek, B., Siebold, L., Rogers, M. B., Kufen, A., & Morowitz, M. J. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izx035 · Cited by 135
Emerging pharmacotherapy for inflammatory bowel diseases
Luo, H., Cao, G., Luo, C., Tan, D., Vong, C. T., Xu, Y., Wang, S., Lu, H., Wang, Y., & Jing, W. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106146 · Cited by 136
Host-Microbiota Interactions Shape Local and Systemic Inflammatory Diseases
Grigg, J. B., & Sonnenberg, G. F. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1601621 · Cited by 130
AGA Technical Review on the Management of Mild-to-Moderate Ulcerative Colitis
Singh, S., Feuerstein, J. D., Binion, D. G., & Tremaine, W. J. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.12.008 · Cited by 130
Lopetuso, L. R., Deleu, S., Godny, L., Petito, V., Puca, P., Facciotti, F., Sokol, H., Ianiro, G., Masucci, L., Abreu, M., et al. (2023) · Gut · doi:10.1136/gutjnl-2023-329948 · Cited by 129
Davidovics, Z. H., Michail, S. K., Nicholson, M. R., Kociolek, L. K., Pai, N., Hansen, R., Schwerd, T., Maspons, A., Shamir, R., Szajewska, H., et al. (2018) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002205 · Cited by 132
Interrogating host immunity to predict treatment response in inflammatory bowel disease
Digby-Bell, J. L., Atreya, R. N., Monteleone, G., & Powell, N. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0228-5 · Cited by 130
Crothers, J. W., Chu, N. D., Nguyen, L. T. T., Phillips, M., Collins, C. C., Fortner, K. A., del Río, R., Lavoie, B. A., CALLAS, P. W., Velez, M., et al. (2021) · BMC Gastroenterology · doi:10.1186/s12876-021-01856-9 · Cited by 133
Qazi, T., Amaratunga, T., Barnes, E. L., Fischer, M., Kassam, Z., & Allegretti, J. R. (2017) · Gut Microbes · doi:10.1080/19490976.2017.1353848 · Cited by 128
Fang, H., Fu, L., & Wang, J. (2018) · BioMed Research International · doi:10.1155/2018/8941340 · Cited by 128
The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease
Chakaroun, R., Olsson, L. M., & Bäckhed, F. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00771-0 · Cited by 131
Wu, R., Xiong, R., Li, Y., Chen, J., & Yan, R. (2023) · Journal of Autoimmunity · doi:10.1016/j.jaut.2023.103062 · Cited by 124
Basso, P. J., Câmara, N. O. S., & Sales‐Campos, H. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01571 · Cited by 121
Ng, S. C., Kamm, M. A., Yeoh, Y. K., Chan, P. K. S., Zuo, T., Tang, W., Sood, A., Andoh, A., Ohmiya, N., Zhou, Y., et al. (2019) · Gut · doi:10.1136/gutjnl-2019-319407 · Cited by 121
Holster, S., Lindqvist, C. M., Repsilber, D., Salonen, A., de Vos, W. M., König, J., & Brummer, R. J. (2019) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000034 · Cited by 123
International consensus statement on microbiome testing in clinical practice
Porcari, S., Mullish, B. H., Asnicar, F., Ng, S. C., Zhao, L., Hansen, R., O’Toole, P. W., Raes, J., Hold, G. L., Putignani, L., et al. (2024) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(24)00311-x · Cited by 131
The gut microbiome as a target for IBD treatment: are we there yet
Knox, N. C., Forbes, J. D., Van Domselaar, G., & Bernstein, C. N. (2019) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-019-00221-w · Cited by 117
Fecal Microbiota Transplantation for Ulcerative Colitis: A Systematic Review and Meta-Analysis
Shi, Y., Dong, Y., Huang, W., Zhu, D., Mao, H., & Su, P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157259 · Cited by 121
Ulcerative Colitis: Current and Emerging Treatment Strategies
Kayal, M., & Shah, S. C. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm9010094 · Cited by 117
Zhong, S., Sun, Y.-Q., Huo, J.-X., Xu, W., Yang, Y.-N., Yang, J.-B., Wu, W.-J., Liu, Y.-X., Wu, C.-M., & Li, Y.-G. (2024) · iMeta · doi:10.1002/imt2.180 · Cited by 109
Consensus report: faecal microbiota transfer – clinical applications and procedures
König, J., Siebenhaar, A., Högenauer, C., Arkkila, P. E. T., Nieuwdorp, M., Norén, T., Ponsioen, C. Y., Rosien, U., Rossen, N., Satokari, R. M., et al. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13868 · Cited by 115
Self-citationSu, L., Hong, Z., Zhou, T., Jian, Y., Xu, M., Zhang, X., Zhu, X., & Wang, J. (2022) · Scientific Reports · doi:10.1038/s41598-022-05127-9 · Cited by 116
Preclinical disease and preventive strategies in IBD: perspectives, challenges and opportunities
Torres, J., Burisch, J. M., Riddle, M. S., Dubinsky, M. C., & Colombel, J. (2016) · Gut · doi:10.1136/gutjnl-2016-311785 · Cited by 117
Delivery routes for faecal microbiota transplants: Available, anticipated and aspired
Gulati, M., Singh, S. K., Corrie, L., Kaur, I. P., & Chandwani, L. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104954 · Cited by 116
Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An Update
Tan, P., Li, X., Shen, J., & Feng, Q. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.574533 · Cited by 112
Sarbagili Shabat, C., Scaldaferri, F., Zittan, E., Hirsch, A., Mentella, M. C., Musca, T., Cohen, N. A., Ron, Y., Fliss Isakov, N., Pfeffer, J., et al. (2022) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjab165 · Cited by 110
Jacob, V. E., Crawford, C. V., Cohen‐Mekelburg, S., Viladomiu, M., Putzel, G., Schneider, Y., Chabouni, F., OʼNeil, S., Bosworth, B. P., Woo, V., et al. (2017) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000001132 · Cited by 114
Deleu, S., Arnauts, K., Deprez, L., Machiels, K., Ferrante, M., Huys, G. R. B., Thevelein, J. M., Raes, J., & Vermeire, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24010768 · Cited by 110
Caldeira, L. D. F., Borba, H. H. L., Tonin, F. S., Wiens, A., Fernández-Llimós, F., & Pontarolo, R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0238910 · Cited by 108
Antibiotics in the pathogenesis of diabetes and inflammatory diseases of the gastrointestinal tract
Fenneman, A. C., Weidner, M., Chen, L. A., Nieuwdorp, M., & Blaser, M. J. (2022) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-022-00685-9 · Cited by 112
Haifer, C., Kelly, C. R., Paramsothy, S., Andresen, D. N., Papanicolas, L. E., McKew, G. L., Borody, T. J., Kamm, M. A., Costello, S. P., Andrews, J. M., et al. (2020) · Gut · doi:10.1136/gutjnl-2019-320260 · Cited by 108
Chang, C., Liao, Y.-C., Huang, C., Lin, C.-M., Cheung, C. H. Y., Ruan, J., Yu, W.-H., Tsai, Y.-T., Lin, I.-J., Huang, C., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.110016 · Cited by 108
Gut Microbiota Implications for Health and Welfare in Farm Animals: A Review
Chen, S., Luo, S., & Yan, C. (2021) · Animals · doi:10.3390/ani12010093 · Cited by 111
The Gut Microbiome in Multiple Sclerosis: A Potential Therapeutic Avenue
Kirby, T. O., & Ochoa‐Repáraz, J. (2018) · Medical Sciences · doi:10.3390/medsci6030069 · Cited by 114
Britton, G. J., Contijoch, E. J., Spindler, M. P., Aggarwala, V., Dogan, B., Bongers, G., Mateo, L. S., Baltus, A. E., Das, A., Gevers, D., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1922189117 · Cited by 106
Bile acids activated receptors in inflammatory bowel disease
Biagioli, M., Marchianò, S., Carino, A., Di Giorgio, C., Santucci, L., Distrutti, E., & Fiorucci, S. (2021) · Cells · doi:10.3390/cells10061281 · Cited by 103
Wilson, B. C., Vatanen, T., Jayasinghe, T. N., Leong, K. S. W., Derraik, J. G. B., Albert, B. B., Chiavaroli, V., Svirskis, D. M., Beck, K. L., Conlon, C. A., et al. (2021) · Microbiome · doi:10.1186/s40168-021-01060-7 · Cited by 105
Colonic transendoscopic enteral tubing: A novel way of transplanting fecal microbiota
Peng, Z., Xiang, J., He, Z., Zhang, T., Xu, L., Cui, B., Li, P., Huang, G., Ji, G., Nie, Y., et al. (2016) · Endoscopy International Open · doi:10.1055/s-0042-105205 · Cited by 105
Probiotics and immunity: provisional role for personalized diets and disease prevention
Bubnov, R. V., Spivak, M. Y., Lazarenko, L. M., Bomba, A., & Boyko, N. (2015) · The EPMA Journal · doi:10.1186/s13167-015-0036-0 · Cited by 102
Ihekweazu, F. D., Fofanova, T. Y., Queliza, K., Nagy‐Szakal, D., Stewart, C. J., Engevik, M. A., Hultén, K. G., Tatevian, N., Graham, D. Y., Versalovic, J. A., et al. (2019) · Gut Microbes · doi:10.1080/19490976.2018.1560753 · Cited by 99
Fecal Microbial Transplantation for Diseases Beyond Recurrent Clostridium Difficile Infection
D’Haens, G., & Jobin, C. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.04.053 · Cited by 104
Self-citationChehade, N. E. H., Ghoneim, S., Shah, S. N., Chahine, A., Mourad, F. H., Francis, F. F., Binion, D. G., Farraye, F. A., & Hashash, J. G. (2022) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izac135 · Cited by 97
Fecal microbiota transplantation: Emerging applications in autoimmune diseases
Yang, R., Chen, Z., & Cai, J. (2023) · Journal of Autoimmunity · doi:10.1016/j.jaut.2023.103038 · Cited by 103
Fecal transplantation for treatment of inflammatory bowel disease
Imdad, A., Pandit, N. G., Zaman, M., Minkoff, N. Z., Tanner‐Smith, E. E., Gomez-Duarte, O. G., Acra, S. A., & Nicholson, M. R. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012774.pub3 · Cited by 103
Intestinal Microbiota Modulation in Obesity-Related Non-alcoholic Fatty Liver Disease
Porras, D., Nistal, E., Martínez‐Flórez, S., González‐Gallego, J., García‐Mediavilla, M. V., & Sánchez‐Campos, S. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01813 · Cited by 97
Relationship between the microbiome and ocular health
Cavuoto, K. M., Banerjee, S., & Galor, A. (2019) · The Ocular Surface · doi:10.1016/j.jtos.2019.05.006 · Cited by 95
Fecal Microbial Transplantation and Its Potential Application in Cardiometabolic Syndrome
Leshem, A., Horesh, N., & Elinav, E. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01341 · Cited by 96
Oral delivery of bacteria: Basic principles and biomedical applications
Li, S., Jiang, W., Zheng, C., Shao, D., Liu, Y., Huang, S., Han, J., Ding, J., Tao, Y., & Li, M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.011 · Cited by 95
Knoll, R. L., Forslund, S. K., Kultima, J. R., Meyer, C. U., Kullmer, U., Sunagawa, S., Bork, P., & Gehring, S. (2016) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00293.2016 · Cited by 98
Protective and pro-inflammatory roles of intestinal bacteria
Webb, C. R., Koboziev, I., Furr, K. L., & Grisham, M. B. (2016) · Pathophysiology · doi:10.1016/j.pathophys.2016.02.002 · Cited by 102
Gut microbiome interventions in human health and diseases
Nie, P., Li, Z., Wang, Y., Zhang, Y., Zhao, M., Luo, J., Du, S., Deng, Z., Chen, J., Wang, Y., et al. (2019) · Medicinal Research Reviews · doi:10.1002/med.21584 · Cited by 94
Feng, J. Q., Chen, Y., Liu, Y., Lin, L., Lin, X., Gong, W., Xia, R., He, J., Sheng, J., Cai, H., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-41182-6 · Cited by 93
Landy, J., Walker, A. W., Li, J. V., Al-Hassi, H. O., Ronde, E., English, N. R., Mann, E. R., Bernardo, D., McLaughlin, S. D., Parkhill, J., et al. (2015) · Scientific Reports · doi:10.1038/srep12955 · Cited by 93
Yao, W., Gong, J., Zhu, W., Tian, H., Ding, C., Gu, L., Li, N., & Li, J. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0869-2 · Cited by 97
Mechanisms of Microbe–Host Interaction in Crohn’s Disease: Dysbiosis vs. Pathobiont Selection
Buttó, L. F., Schaubeck, M., & Haller, D. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00555 · Cited by 97
Ethical Issues in Fecal Microbiota Transplantation in Practice
Ma, Y., Liu, J., Rhodes, C., Nie, Y., & Zhang, F. (2017) · The American Journal of Bioethics · doi:10.1080/15265161.2017.1299240 · Cited by 92
Microbial Population Changes and Their Relationship with Human Health and Disease
Álvarez‐Mercado, A. I., Navarro-Oliveros, M., Robles-Sánchez, C., Plaza‐Díaz, J., Sáez‐Lara, M. J., Muñoz‐Quezada, S., Fontana, L., & Abadía‐Molina, F. (2019) · Microorganisms · doi:10.3390/microorganisms7030068 · Cited by 93
Standardized Preparation for Fecal Microbiota Transplantation in Pigs
Hu, J. P., Chen, L., Tang, Y., Xie, C., Xu, B., Shi, M. Y., Zheng, W., Zhou, S., Wang, X., Liu, L., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01328 · Cited by 92
An ecological framework to understand the efficacy of fecal microbiota transplantation
Xiao, Y., Angulo, M. T., Lao, S., Weiss, S. T., & Liu, Y.-Y. (2020) · Nature Communications · doi:10.1038/s41467-020-17180-x · Cited by 89
Emerging Therapies for Inflammatory Bowel Disease
Weisshof, R., Jurdi, K. E., Zmeter, N., & Rubin, D. T. (2018) · Advances in Therapy · doi:10.1007/s12325-018-0795-9 · Cited by 89
Fang, H., Fu, L., Li, X., Wang, J., Xiong, K., Su, Y., & Zhang, L. (2021) · Microbial Cell Factories · doi:10.1186/s12934-021-01513-6 · Cited by 88
Gut microbiota in pathophysiology, diagnosis, and therapeutics of inflammatory bowel disease
Pandey, H., Jain, D., Tang, D. W. T., Wong, S. H., & Lal, D. (2023) · Intestinal Research · doi:10.5217/ir.2023.00080 · Cited by 95
Nicco, C., Paule, A., Konturek, P. C., & Edeas, M. A. (2020) · Diseases · doi:10.3390/diseases8020009 · Cited by 91
Gut microbial metabolome in inflammatory bowel disease: From association to therapeutic perspectives
Li, M., Yang, L., Mu, C., Sun, Y., Gu, Y., Chen, D., Liu, T., & Cao, H. (2022) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2022.03.038 · Cited by 89
The Gut Microbiota in Inflammatory Bowel Disease
Sheehan, D., & Shanahan, F. (2017) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2016.09.011 · Cited by 88
Nusbaum, D. J., Sun, F., Ren, J., Zhu, Z., Ramsy, N., Pervolarakis, N., Kunde, S. S., England, W., Gao, B., Fiehn, O., et al. (2018) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiy133 · Cited by 87
Metadata
- Authors
- Rossen, N. G., Fuentes, S., van der Spek, M. J., Tijssen, J. G., Hartman, J. H. A., Duflou, A., Löwenberg, M., van den Brink, G. R., Mathus-Vliegen, E. M. H., de Vos, W. M., Zoetendal, E. G., D’Haens, G. R., & Ponsioen, C. Y.
- Affiliations
- Amsterdam UMC Location University of Amsterdam (NL)
- Wageningen University & Research (NL)
- Corresponding author
- Ponsioen, Cyriel Y.
- ORCID
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 149
- Issue
- 1
- Pages
- 110-118.e4
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W1994882377
- Cited by
- 921
- References
- 29
- Citations by year
- 2026: 30 · 2025: 45 · 2024: 64 · 2023: 69 · 2022: 86 · 2021: 93 · 2020: 128 · 2019: 113 · 2018: 84 · 2017: 87 · 2016: 83 · 2015: 36
- FWCI
- 66.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Socio-Environmental Systems Modeling (acceptedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Microscopic Colitis
- Keywords
- fecal microbiota transplantation, ulcerative colitis, clinical remission, endoscopic remission, Clostridium cluster XIVa, Clostridium cluster IV, gut microbiota composition, adverse events
- MeSH terms
- Adult, Aged, Biological Therapy, Colitis, Ulcerative, Double-Blind Method, Feces, Female, Humans, Intubation, Gastrointestinal, Male, Middle Aged, Remission Induction, Treatment Outcome, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
