The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.
Targeted and Immune-Based Therapies for Hepatocellular Carcinoma
Open accessAbstract
Treatment options for patients with hepatocellular carcinoma (HCC) are rapidly changing based on positive results from phase 3 trials of targeted and immune-based therapies. More agents designed to target specific pathways and immune checkpoints are in clinical development. Some agents have already been shown to improve outcomes of patients with HCC, as first- and second- line therapies, and are either awaiting approval by the Food and Drug Administration or have been recently approved. We summarize the targeted and immune-based agents in trials of patients with advanced HCC and discuss the future of these strategies for liver cancer.
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Cites
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Self-citationEASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
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Cited by
Locoregional therapies in the era of molecular and immune treatments for hepatocellular carcinoma
Llovet, J. M., De Baere, T., Kulik, L., Haber, P. K., Greten, T. F., Meyer, T., & Lencioni, R. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00395-0 · Cited by 1,044
Self-citationZhang, P.-F., Gao, C., Huang, X.-Y., Lu, J.-C., Guo, X.-J., Shi, G.-M., Cai, J.-B., & Ke, A.-W. (2020) · Molecular Cancer · doi:10.1186/s12943-020-01222-5 · Cited by 593
Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma
Cheng, A.-L., Hsu, C., Chan, S. L., Choo, S.-P., & Kudo, M. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2019.09.025 · Cited by 528
Tumor Immune Microenvironment and Immunosuppressive Therapy in Hepatocellular Carcinoma: A Review
Oura, K., Morishita, A., Tani, J., & Masaki, T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115801 · Cited by 426
Trial Design and Endpoints in Hepatocellular Carcinoma: AASLD Consensus Conference
Llovet, J. M., Villanueva, A., Marrero, J. A., Schwartz, M., Meyer, T., Galle, P. R., Lencioni, R., Greten, T. F., Kudo, M., Mandrekar, S. J., et al. (2021) · Hepatology · doi:10.1002/hep.31327 · Cited by 413
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Metadata
- Authors
- Greten, T. F., Lai, C. W., Li, G., & Staveley-O’Carroll, K. F.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 156
- Issue
- 2
- Pages
- 510-524
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2895336603
- Cited by
- 294
- References
- 124
- FWCI
- 13.60
- Type
- journal article
- Language
- en
- Open access
- green
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- Greten, T. F., Lai, C. W., Li, G., & Staveley-O’Carroll, K. F. (2019). Targeted and Immune-Based Therapies for Hepatocellular Carcinoma. Gastroenterology. https://doi.org/10.1053/j.gastro.2018.09.051
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