Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 597

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Recent Insights into the Pathogenesis of Pre-eclampsia

Roberts, J.M., Lain, K.Y.·2002·Placenta
DOI 10.1053/plac.2002.0819
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1053/plac.2002.0819

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 6 references

Research works printed but not linked: 218

  1. Abi-Said, 1995, Case-control study of the risk factors for eclampsia, Am J Epidemiol, 142, 437, 10.1093/oxfordjournals.aje.a117652 · DOI
  2. Abitbol, 1976, Production of experimental toxemia in the pregnant dog, Obstet Gynecol, 48, 548
  3. Adam, 1998, Plasma atrial natriuretic peptide levels in preeclampsia and eclampsia, Journal of Maternal–Fetal Investigation, 8, 85
  4. Allaire, 2000, Placental apoptosis in preeclampsia, Obstet Gynecol, 96, 271, 10.1016/S0029-7844(00)00895-4 · DOI · Paper page
  5. Anim-Nyame, 2000, Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia, Hum Reprod, 15, 2033, 10.1093/humrep/15.9.2033 · DOI
  6. Arias, 1993, Maternal placental vasculopathy and infection: Two distinct subgroups among patients with preterm labor and preterm ruptured membranes, Am J Obstet Gynecol, 168, 585, 10.1016/0002-9378(93)90499-9 · DOI · Paper page
  7. Arngrimsson, 1995, Analysis of different inheritance patterns in preeclampsia/eclampsia syndrome, Hypertension in Pregnancy, 14, 27, 10.3109/10641959509058048 · DOI
  8. Ashworth, 1996, A comparison of endothelium-dependent relaxation in omental and myometrial resistance arteries in pregnant and nonpregnant women, Am J Obstet Gynecol, 175, 1307, 10.1016/S0002-9378(96)70046-7 · doi:10.1016/s0002-9378(96)70046-7
  9. Assali, 1950, Studies on autonomic blockade. I. Comparison between the effects of tetraethylammonium chloride (TEAÇ, and high selective spinal anesthesia on blood pressure of normal and toxemic pregnancy, J Clin Invest, 29, 1354, 10.1172/JCI102373 · doi:10.1172/jci102373
  10. Baker, 1996, Plasma of preeclamptic women stimulates and then inhibits endothelial prostacyclin, Hypertension, 27, 56, 10.1161/01.HYP.27.1.56 · doi:10.1161/01.hyp.27.1.56
  11. Baker, 1995, Plasma from women with preeclampsia increases endothelial cell nitric oxide production, Hypertension, 26, 244, 10.1161/01.HYP.26.2.244 · DOI
  12. Bass, 1994, Human cytotrophoblast invasion is up-regulated by epidermal growth factor: evidence that paracrine factors modify this process, Dev Biol, 164, 1, 10.1006/dbio.1994.1223 · DOI · Paper page
  13. Benyo, 1997, Hypoxia stimulates cytokine production by villous explants from the human placenta, Journal of Clinical Endocrinology & Metabolism, 82, 1582, 10.1210/jc.82.5.1582 · DOI · Paper page
  14. Boffa, 1998, Predictive value of plasma thrombomodulin in preeclampsia and gestational hypertension, Thromb Haemost, 79, 1092, 10.1055/s-0037-1615021 · DOI
  15. Bosio, 1999, Maternal central hemodynamics in hypertensive disorders of pregnancy, Obstetrics & Gynecology, 94, 978, 10.1016/S0029-7844(99)00430-5 · doi:10.1016/s0029-7844(99)00430-5
  16. Branch, 1992, Sera from preeclamptic patients contain factor(s) that stimulate prostacyclin production by human endothelial cells, Prostaglandins Leukot Essent Fatty Acids, 45, 191, 10.1016/0952-3278(92)90112-V · doi:10.1016/0952-3278(92)90112-v
  17. Branch, 1994, Pre-eclampsia and serum antibodies to oxidised low-density lipoprotein, Lancet, 343, 645, 10.1016/S0140-6736(94)92639-5 · DOI
  18. Brown, 1997, The renin-angiotensin-aldosterone system in pre-eclampsia, Clin Exp Hypertens, 19, 713, 10.3109/10641969709083181 · DOI
  19. Bussen, 1998, Plasma renin activity and aldosterone serum concentration are decreased in severe preeclampsia but not in the HELLP-Syndrome, Acta Obstet Gynecol Scand, 77, 609, 10.1034/j.1600-0412.1998.770606.x · DOI
  20. Calvert, 1996, Poor predictive value of platelet count, mean platelet volume and serum urate in hypertension in pregnancy, European Journal of Obstetrics, Gynecology and Reproductive Biology, 64, 179, 10.1016/0301-2115(95)02336-4 · doi:10.1016/0301-2115(95)02336-4
  21. Calvin, 1988, Factor VIII: von Willebrand factor patterns in the plasma of patients with pre-eclampsia, Am J Perinatol, 5, 29, 10.1055/s-2007-999648 · doi:10.1055/s-2007-999648
  22. Campbell, 1983, Evans blue disappearance rate in normal and pre-eclamptic pregnancy, Clinical and Experimental Hypertension. Part B. Hypertension In Pregnancy, 2, 163, 10.3109/10641958309023468 · DOI
  23. Caniggia, 1999, Inhibition of TGF-beta 3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies, J Clin Invest, 103, 1641, 10.1172/JCI6380 · DOI · Paper page
  24. Cargnoni, 1994, Lipid peroxidation in normal pregnancy and preeclampsia, Adv Exp Med Biol, 366, 420, 10.1007/978-1-4615-1833-4_37 · DOI
  25. Cavanagh, 1977, Experimental toxemia in the pregnant primate, Am J Obstet Gynecol, 128, 75, 10.1016/0002-9378(77)90296-4 · DOI
  26. Cester, 1994, Pregnancy induced hypertension: a role for peroxidation in microvillus plasma membranes, Mol Cell Biochem, 131, 151, 10.1007/BF00925951 · DOI
  27. Chappell, 1999, Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial, Lancet, 354, 810, 10.1016/S0140-6736(99)80010-5 · DOI · Paper page
  28. Chesley, 1966, Vascular reactivity in normal and toxemic pregnancy, Clin Obstet Gynecol, 9, 871, 10.1097/00003081-196612000-00003 · DOI
  29. Chesley, 1976, The remote prognosis of eclamptic women: Sixth periodic report, Am J Obstet Gynecol, 124, 446, 10.1016/0002-9378(76)90168-X · DOI · Paper page
  30. Cockell, 1997, Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial function, British Journal of Obstetrics and Gynaecology, 104, 235, 10.1111/j.1471-0528.1997.tb11052.x · DOI · Paper page
  31. Cockell, 1997, Flow-mediated vasodilatation is enhanced in normal pregnancy but reduced in preeclampsia, Hypertension, 30, 247, 10.1161/01.HYP.30.2.247 · DOI
  32. Conrad, 1997, Placental cytokines and the pathogenesis of preeclampsia, Am J Reprod Immunol, 37, 240, 10.1111/j.1600-0897.1997.tb00222.x · DOI · Paper page
  33. Conrad, 1998, Circulating levels of immunoreactive cytokines in women with preeclampsia, Am J Reprod Immunol, 40, 102, 10.1111/j.1600-0897.1998.tb00398.x · DOI · Paper page
  34. Craven, 1998, Decidual spiral artery remodelling begins before cellular interaction with cytotrophoblasts, Placenta, 19, 241, 10.1016/S0143-4004(98)90055-8 · DOI · Paper page
  35. Cross, 1994, Implantation and the placenta: key pieces of the development puzzle. [Review], Science, 266, 1508, 10.1126/science.7985020 · DOI · Paper page
  36. Damsky, 1992, Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo, J Clin Invest, 89, 210, 10.1172/JCI115565 · DOI · Paper page
  37. Daniel, 1998, Plasma interleukin-12 is elevated in patients with preeclampsia, Am J Reprod Immunol, 39, 376, 10.1111/j.1600-0897.1998.tb00372.x · DOI
  38. Davidge, 1995, NOS expression is increased in endothelial cells exposed to plasma from women with preeclampsia, Am J Physiol, 269, H1106
  39. Davidge, 1996, Distinct factors in plasma of preeclamptic women increase endothelial nitric oxide or prostacyclin, Hypertension, 28, 758, 10.1161/01.HYP.28.5.758 · doi:10.1161/01.hyp.28.5.758
  40. Davidge, 1996, Evidence of endothelial activation and endothelial activators in cord blood of infants of preeclamptic women, Am J Obstet Gynecol, 175, 1301, 10.1016/S0002-9378(96)70045-5 · doi:10.1016/s0002-9378(96)70045-5
  41. deGroot, 1993, New insights into the etiology of pre-eclampsia, Ann Med, 25, 243, 10.3109/07853899309147870 · doi:10.3109/07853899309147870
  42. deGroot, 1997, Increased von Willebrand factor expression in an experimental model of preeclampsia produced by reduction of uteroplacental perfusion pressure in conscious rhesus monkeys, Hypertension in Pregnancy, 16, 177, 10.3109/10641959709031635 · DOI
  43. deGroot, 1995, Plasma from preeclamptic women increases human endothelial cell prostacyclin production without changes in enzyme activity or mass, Am J Obstet Gynecol, 172, 976, 10.1016/0002-9378(95)90030-6 · doi:10.1016/0002-9378(95)90030-6
  44. Dekker, 1994, Etiology and pathophysiology of preeclampsia, Zentralbl Gynakol, 116, 57
  45. Dekker, 1995, Underlying disorders associated with severe early-onset preeclampsia, Am J Obstet Gynecol, 173, 1042, 10.1016/0002-9378(95)91324-6 · DOI · Paper page
  46. Demoerloose, 1998, Thrombomodulin levels during normal pregnancy, at delivery and in the postpartum—comparison with tissue-type plasminogen activator and plasminogen aActivator inhibitor-1, Thromb Haemost, 79, 554, 10.1055/s-0037-1614943 · doi:10.1055/s-0037-1614943
  47. DeWolf, 1975, The ultrastructure of acute atherosis in hypertensive pregnancy, Am J Obstet Gynecol, 123, 164, 10.1016/0002-9378(75)90522-0 · DOI · Paper page
  48. DiFederico, 1999, Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall, Am J Pathol, 155, 293, 10.1016/S0002-9440(10)65123-1 · DOI · Paper page
  49. Dizon-Townson, 1996, The factor V Leiden mutation may predispose women to severe preeclampsia, Am J Obstet Gynecol, 175, 902, 10.1016/S0002-9378(96)80022-6 · DOI · Paper page
  50. Easterling, 1992, The maternal hemodynamics of preeclampsia, Clin Obstet Gynecol, 35, 375, 10.1097/00003081-199206000-00018 · doi:10.1097/00003081-199206000-00018
  51. Efiong, 1975, Pregnancy in the overweight Nigerian, Br J Obstet Gynaecol, 82, 903, 10.1111/j.1471-0528.1975.tb00596.x · doi:10.1111/j.1471-0528.1975.tb00596.x
  52. Ekholm, 1997, Heart rate and blood pressure variabilities are increased in pregnancy-induced hypertension, Am J Obstet Gynecol, 177, 1208, 10.1016/S0002-9378(97)70041-3 · DOI
  53. Endresen, 1998, Serum from preeclamptic women induces vascular cell adhesion molecule-1 expression on human endothelial cells in vitro—a possible role of increased circulating levels of free fatty acids, Am J Obstet Gynecol, 179, 665, 10.1016/S0002-9378(98)70061-4 · doi:10.1016/s0002-9378(98)70061-4
  54. Eneroth, 1998, Increased serum concentrations of interleukin-2 receptor in the first trimester in women who later developed severe preeclampsia, Acta Obstet Gynecol Scand, 77, 591, 10.1034/j.1600-0412.1998.770602.x · doi:10.1034/j.1600-0412.1998.770602.x
  55. Eskenazi, 1993, Fetal growth retardation in infants of multiparous and nulliparous women with preeclampsia, Am J Obstet Gynecol, 169, 1112, 10.1016/0002-9378(93)90265-K · DOI
  56. Ferris, 1991, Pregnancy, preeclampsia, and the endothelial cell, New England Journal of Medicine, 325, 1439, 10.1056/NEJM199111143252009 · doi:10.1056/nejm199111143252009
  57. Fisher, 1981, Hypertension in pregnancy: Clinical-pathological correlations and remote prognosis, Medicine, 60, 267, 10.1097/00005792-198107000-00002 · DOI · Paper page
  58. Fisher, 1989, Adhesive and degradative properties of human placental cytotrophoblast cells in vitro, The Journal of Cell Biology International, 109, 891, 10.1083/jcb.109.2.891 · DOI · Paper page
  59. Fisher, 2000, Human cytomegalovirus infection of placental cytotrophoblasts In vitro and In utero: implications for transmission and pathogenesis [In Process Citation], J Virol, 74, 6808, 10.1128/JVI.74.15.6808-6820.2000 · DOI · Paper page
  60. Fitzgerald, 1987, Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension, Circulation, 75, 956, 10.1161/01.CIR.75.5.956 · DOI · Paper page
  61. Friedman, 1994, Plasma cellular fibronectin as a measure of endothelial involvement in preeclampsia and intrauterine growth retardation, Am J Obstet Gynecol, 170, 838, 10.1016/S0002-9378(94)70295-0 · DOI
  62. Friedman, 1995, Biochemical corroboration of endothelial involvement in severe preeclampsia, Am J Obstet Gynecol, 172, 202, 10.1016/0002-9378(95)90113-2 · DOI
  63. Friedman, 1991, Pathophysiology of preeclampsia, Clin Perinatol, 18, 661, 10.1016/S0095-5108(18)30490-1 · DOI
  64. Furugori, 1997, Levels of hepatocyte growth factor and its messenger ribonucleic acid in uncomplicated pregnancies and those complicated by preeclampsia, J Clin Endocrinol Metab, 82, 2726, 10.1210/jc.82.8.2726 · doi:10.1210/jc.82.8.2726
  65. Gaber, 1994, Renal pathology in pre-eclampsia. [Review] [68 refs], Baillieres Clinical Obstetrics & Gynaecology, 8, 443, 10.1016/S0950-3552(05)80330-X · DOI
  66. Gant, 1973, A study of angiotensin II pressor response throughout primigravid pregnancy, J Clin Invest, 52, 2682, 10.1172/JCI107462 · DOI · Paper page
  67. Garzetti, 1993, Altered lipid composition, increased lipid peroxidation, and altered fluidity of the membrane as evidence of platelet damage in preeclampsia, Obstet Gynecol, 81, 337
  68. Geary, 1999, Leptin concentrations in maternal serum and cord blood: relationship to maternal anthropometry and fetal growth [see comments], British Journal of Obstetrics & Gynaecology, 106, 1054, 10.1111/j.1471-0528.1999.tb08113.x · DOI
  69. Genbacev, 1996, Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia, J Clin Invest, 97, 540, 10.1172/JCI118447 · DOI · Paper page
  70. Genbacev, 1997, Regulation of human placental development by oxygen tension, Science, 277, 1669, 10.1126/science.277.5332.1669 · DOI · Paper page
  71. Gilmour, 1998, Increased umbilical cellular fibronectin concentrations are associated with a decreased prevalence of growth restriction in preeclampsia, Journal of the Society for Gynecologic Investigation
  72. Glueck, 2001, Genetic hypofibrinolysis in complicated pregnancies, Obstet Gynecol, 97, 44, 10.1016/S0029-7844(00)01094-2 · doi:10.1016/s0029-7844(00)01094-2
  73. Grandone, 1997, Factor V Leiden, C>T MTHFR polymorphism and genetic susceptibility to preeclampsia, Thromb Haemost, 77, 1052, 10.1055/s-0038-1656110 · DOI · Paper page
  74. Gray, 1998, Maternal hypertension and neurodevelopmental outcome in very preterm infants, Arch Dis Child, 79, F88, 10.1136/fn.79.2.F88 · DOI
  75. Greenwood, 1998, Sympathetic nerve discharge in normal pregnancy and pregnancy-induced hypertension, J Hypertens, 16, 617, 10.1097/00004872-199816050-00009 · DOI
  76. Greer, 1994, Increased concentrations of cytokines interleukin-6 and interleukin-1 receptor antagonist in plasma of women with preeclampsia: a mechanism for endothelial dysfunction?, Obstet Gynecol, 84, 937
  77. Higgins, 1998, Circulating vascular cell adhesion molecule-1 in pre-eclampsia, gestational hypertension, and normal pregnancy—evidence of selective dysregulation of vascular cell adhesion molecule-1 homeostasis in pre-eclampsia, Am J Obstet Gynecol, 179, 464, 10.1016/S0002-9378(98)70380-1 · DOI
  78. Highman, 1998, Longitudinal changes in maternal serum leptin concentrations, body composition, and resting metabolic rate in pregnancy, Am J Obstet Gynecol, 178, 1010, 10.1016/S0002-9378(98)70540-X · DOI · Paper page
  79. Hodgkinson, 1967, Experimental hypertensive disease of pregnancy, Obstet Gynecol, 30, 371
  80. Hsu, 1995, Thrombomodulin levels in preeclampsia, gestational hypertension, and chronic hypertension, Obstet Gynecol, 86, 897, 10.1016/0029-7844(95)00326-M · doi:10.1016/0029-7844(95)00326-m
  81. Hubel, 1997, Oxidative stress and preeclampsia, Fetal and Maternal Medicine Review, 9, 73, 10.1017/S0965539597000065 · doi:10.1017/s0965539597000065
  82. Hubel, 1997, Prevalence of small low-density lipoproteins is increased in preeclampsia, J Soc Gynecol Invest, 4, 95A
  83. Hubel, 1996, Fasting serum triglycerides, free fatty acids, and malondialdehyde are increased in preeclampsia, are positively correlated, and decrease within 48 hours post partum, Am J Obstet Gynecol, 174, 975, 10.1016/S0002-9378(96)70336-8 · DOI · Paper page
  84. Hubel, 1999, Association of pre-eclampsia with common coding sequence variations in the lipoprotein lipase gene, Clin Genet, 56, 289, 10.1034/j.1399-0004.1999.560406.x · DOI
  85. Hubel, 2000, Dyslipoproteinaemia in postmenopausal women with a history of eclampsia, Br J Obstet Gynaecol, 107, 776, 10.1111/j.1471-0528.2000.tb13340.x · DOI
  86. Huppertz, 1999, Apoptosis cascade progresses during turnover of human trophoblast: analysis of villous cytotrophoblast and syncytial fragments in vitro, Lab Invest, 79, 1687
  87. Hutt, 1994, Increased platelet volume and aggregation precede the onset of preeclampsia, Obstet Gynecol, 83, 146
  88. Irwin, 1994, The risk of pregnancy-induced hypertension: black and white differences in a military population, Am J Public Health, 84, 1508, 10.2105/AJPH.84.9.1508 · DOI
  89. Ishitobi, 1991, Morphometric analysis of the glomerular capillary area—a comparison of minimal change nephrotic syndrome, focal glomerular sclerosis, and preeclampsia, Journal of Pathology, 165, 329, 10.1002/path.1711650409 · doi:10.1002/path.1711650409
  90. Joffe, 1998, The relationship between abnormal glucose tolerance and hypertensive disorders of pregnancy in healthy nulliparous women, Am J Obstet Gynecol, 179, 1032, 10.1016/S0002-9378(98)70210-8 · DOI · Paper page
  91. Joffe, 1998, The relationship between abnormal glucose tolerance and hypertensive disorders of pregnancy in healthy nulliparous women. Calcium for Preeclampsia Prevention (CPEP) Study Group, Am J Obstet Gynecol, 179, 1032, 10.1016/S0002-9378(98)70210-8 · DOI · Paper page
  92. Kaaja, 1995, Serum lipoproteins, insulin, and urinary prostanoid metabolites in normal and hypertensive pregnant women, Obstet Gynecol, 85, 353, 10.1016/0029-7844(94)00380-V · DOI · Paper page
  93. Khaliq, 1999, Hypoxia down-regulates placenta growth factor, whereas fetal growth restriction up-regulates placenta growth factor expression: molecular evidence for ‘placental hyperoxia’ in intrauterine growth restriction, Lab Invest, 79, 151
  94. Khan, 1995, Are non-diabetic women with abnormal glucose screening test at increased risk of pre-eclampsia, macrosomia and caesarian birth?, JPMA—Journal of the Pakistan Medical Association, 45, 176
  95. Khong, 1991, Acute atherosis in pregnancies complicated by hypertension, small-for-gestational-age infants, and diabetes mellitus, Arch Pathol Lab Med, 115, 722
  96. Khong, 1986, Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants, Br J Obstet Gynaecol, 93, 1049, 10.1111/j.1471-0528.1986.tb07830.x · DOI · Paper page
  97. Khong, 1993, Immunohistologic demonstration of endothelial disruption in acute atherosis in pre-eclampsia, European Journal of Obstetrics, Gynecology, & Reproductive Biology, 51, 193, 10.1016/0028-2243(93)90034-A · DOI
  98. Khong, 1987, Acute atherosis in preeclampsia: Maternal determinants and fetal outcome in the presence of the lesion, Am J Obstet Gynecol, 157, 360, 10.1016/S0002-9378(87)80172-2 · DOI
  99. Kincaid-Smith, 1991, The renal lesion of preeclampsia revisited, Am J Kidney Dis, 17, 144, 10.1016/S0272-6386(12)81119-X · DOI
  100. Kitzmiller, 1973, Immunoflourescent studies of placental bed vessels in pre-eclampsia, Am J Obstet Gynecol, 115, 248, 10.1016/0002-9378(73)90293-7 · doi:10.1016/0002-9378(73)90293-7
  101. Klonoff-Cohen, 1989, An epidemiologic study of contraception and preeclampsia [see comments], Journal of the American Medical Association, 262, 3143, 10.1001/jama.262.22.3143 · doi:10.1001/jama.262.22.3143
  102. Knight, 1998, Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies, Br J Obstet Gynaecol, 105, 632, 10.1111/j.1471-0528.1998.tb10178.x · DOI · Paper page
  103. Knock, 1996, Bradykinin-mediated relaxation of isolated maternal resistance arteries in normal pregnancy and preeclampsia, Am J Obstet Gynecol, 175, 1668, 10.1016/S0002-9378(96)70123-0 · doi:10.1016/s0002-9378(96)70123-0
  104. Knuist, 1998, Riskfactors for preeclampsia in nulliparous women in distinct ethnic Groups—a prospective cohort study, Obstet Gynecol, 92, 174, 10.1016/S0029-7844(98)00143-4 · DOI
  105. Kobashi, 1995, A case-control study of pregnancy-induced hypertension with a genetic predisposition: association of a molecular variant of angiotensinogen in the Japanese women, Hokkaido Igaku Zasshi—Hokkaido Journal of Medical Science, 70, 649
  106. Kraayenbrink, 1993, Endothelial vasoactive mediators in preeclampsia, Am J Obstet Gynecol, 169, 160, 10.1016/0002-9378(93)90154-B · DOI
  107. Kuban, 1992, Maternal toxemia is associated with reduced incidence of germinal matrix hemorrhage in premature babies, J Child Neurol, 7, 70, 10.1177/088307389200700113 · doi:10.1177/088307389200700113
  108. Kupferminc, 2000, Severe preeclampsia and high frequency of genetic thrombophilic mutations, Obstet Gynecol, 96, 45, 10.1016/S0029-7844(00)00861-9 · DOI · Paper page
  109. Kupferminc, 1996, Soluble tumor necrosis factor receptors and interleukin-6 levels in patients with severe preeclampsia, Obstet Gynecol, 88, 420, 10.1016/0029-7844(96)00179-2 · DOI
  110. Kyle, 1995, The angiotensin sensitivity test and low-dose aspirin are ineffective methods to predict and prevent hypertensive disorders in nulliparous pregnancy, Am J Obstet Gynecol, 173, 865, 10.1016/0002-9378(95)90356-9 · DOI
  111. Laivuori, 2000, Leptin during and after preeclamptic or normal pregnancy: Its relation to serum insulin and insulin sensitivity, Metabolism—Clinical and Experimental, 49, 259, 10.1016/S0026-0495(00)91559-2 · DOI
  112. Levy, 2000, Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor, American Journal of Physiology— Cell Physiology, 278, C982, 10.1152/ajpcell.2000.278.5.C982 · DOI · Paper page
  113. Librach, 1994, Interleukin-1B regulates human cytotrophoblast metalloproteinase activity and invasion in vitro, The Journal of Biological Chemistry, 269, 7125, 10.1016/S0021-9258(17)32529-2 · DOI · Paper page
  114. Librach, 1991, 92-kD type IV collagenase mediates invasion of human cytotrophoblasts, The Journal of Cell Biology International, 113, 437, 10.1083/jcb.113.2.437 · DOI · Paper page
  115. Lockwood, 1990, Increased plasma levels of ED1+ cellular fibronectin precede the clinical signs of preeclampsia, Am J Obstet Gynecol, 162, 358, 10.1016/0002-9378(90)90385-K · doi:10.1016/0002-9378(90)90385-k
  116. Lyall, 2000, Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function, FASEB J, 14, 208, 10.1096/fasebj.14.1.208 · DOI
  117. Lyall, 1999, Human trophoblast invasion and spiral artery transformation: the role of nitric oxide, Am J Pathol, 154, 1105, 10.1016/S0002-9440(10)65363-1 · DOI
  118. Malee, 1992, Increases in plasma atrial natriuretic peptide concentration antedate clinical evidence of preeclampsia, Journal of Clinical Endocrinology Metabolism, 74, 1095, 10.1210/jc.74.5.1095 · doi:10.1210/jc.74.5.1095
  119. Many, 2000, Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsia, Am J Pathol, 156, 321, 10.1016/S0002-9440(10)64733-5 · DOI · Paper page
  120. Martin, 2000, Expression of endothelial nitric oxide synthase by extravillous trophoblast cells in the human placenta, Placenta, 21, 23, 10.1053/plac.1999.0428 · doi:10.1053/plac.1999.0428
  121. Martin, 1998, Incidence of intraventricular hemorrhage in neonates under 32 weeks of gestation delivered to mothers with severe pre-eclampsia, Prenatal and Neonatal Medicine, 3, 250
  122. Martinez-Abundis, 2000, Serum leptin levels and the severity of preeclampsia, Arch Gynecol Obstet, 264, 71, 10.1007/s004040000081 · DOI
  123. Maseki, 1981, Lipid peroxide levels and lipid content of serum lipoprotein fractions of pregnant subject with or without pre-eclampsia, Clin Chim Acta, 115, 115
  124. Maseki, 1981, Lipid peroxide levels and lipid content of serum lipoprotein fractions of pregnant subjects with or without preeclampsia, Clinica Chimica Acta, 115, 155, 10.1016/0009-8981(81)90071-1 · DOI · Paper page
  125. Mastrogiannis, 1991, Potential role of endothelin-1 in normal and hypertensive pregnancies, Am J Obstet Gynecol, 165, 1711, 10.1016/0002-9378(91)90020-R · doi:10.1016/0002-9378(91)90020-r
  126. McCarthy, 1993, Abnormal endothelial cell function of resistance arteries from women with preeclampsia, Am J Obstet Gynecol, 168, 1323, 10.1016/0002-9378(93)90389-Z · DOI · Paper page
  127. McCarthy, 1999, Maternal plasma leptin is increased in preeclampsia and positively correlates with fetal cord concentration, Am J Obstet Gynecol, 180, 731, 10.1016/S0002-9378(99)70280-2 · DOI
  128. McCartney, 1969, The acute hypertensive disorders of pregnancy, classified by renal histology, Gynaecologia, 167, 214
  129. Meis, 1998, The preterm prediction study: risk factors for indicated preterm births. Maternal-Fetal Medicine Units Network of the National Institute of Child Health and Human Development, Am J Obstet Gynecol, 178, 562, 10.1016/S0002-9378(98)70439-9 · DOI · Paper page
  130. Mills, 1999, Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study, JAMA, 282, 356, 10.1001/jama.282.4.356 · DOI
  131. Minakami, 1993, Increased levels of plasma thrombomodulin in preeclampsia, Gynecol Obstet Invest, 36, 208, 10.1159/000292631 · doi:10.1159/000292631
  132. Mise, 1998, Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia, J Clin Endocrinol Metab, 83, 3225, 10.1210/jc.83.9.3225 · DOI
  133. Mittendorf, 1996, Preeclampsia. A nested, case-control study of risk factors and their interactions, J Reprod Med, 41, 491
  134. Morgan, 1995, Pre-eclampsia and the angiotensinogen gene, Br J Obstet Gynaecol, 102, 489, 10.1111/j.1471-0528.1995.tb11324.x · doi:10.1111/j.1471-0528.1995.tb11324.x
  135. Murphy, 1995, Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm singleton babies, Lancet, 346, 1449, 10.1016/S0140-6736(95)92471-X · DOI · Paper page
  136. Murphy, 2000, Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy, Arteriosclerosis Thrombosis and Vascular Biology, 20, 266, 10.1161/01.ATV.20.1.266 · DOI
  137. Musci, 1988, Mitogenic activity is increased in the sera of preeclamptic women before delivery, Am J Obstet Gynecol, 159, 1446, 10.1016/0002-9378(88)90572-8 · DOI
  138. Nelson, 1996, Magnesium sulfate and risk of cerebral palsy in very low-birth-weight infants [editorial; comment], Journal of the American Medical Association, 276, 1843, 10.1001/jama.276.22.1843 · doi:10.1001/jama.276.22.1843
  139. Nelson, 1995, Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants?, Pediatrics, 95, 263, 10.1542/peds.95.2.263 · doi:10.1542/peds.95.2.263
  140. Ness, 1996, Heterogeneous causes constituting the single syndrome of preeclampsia: a hypothesis and its implications. [Review], Am J Obstet Gynecol, 175, 1365, 10.1016/S0002-9378(96)70056-X · DOI · Paper page
  141. Nisell, 1998, Pre-eclampsia—a state of sympathetic over-activity, Br J Obstet Gynaecol, 105, 931, 10.1111/j.1471-0528.1998.tb10245.x · DOI
  142. Nova, 1991, Maternal plasma level of endothelin is increased in preeclampsia, Am J Obstet Gynecol, 165, 724, 10.1016/0002-9378(91)90317-K · DOI · Paper page
  143. Oshea, 1998, Prenatal events and the risk of cerebral palsy in very low birth weight infants, Am J Epidemiol, 147, 362, 10.1093/oxfordjournals.aje.a009458 · doi:10.1093/oxfordjournals.aje.a009458
  144. Oshea, 1998, Perinatal Events and the Risk Of Intraparenchymal Echodensity In Very-Low-Birthweight Neonates, Paediatric & Perinatal Epidemiology, 12, 408, 10.1046/j.1365-3016.1998.00134.x · doi:10.1046/j.1365-3016.1998.00134.x
  145. Page, 1939, The relation between hydatid moles, relative ischemia of the gravid uterus, and the placental origin of eclampsia, Am J Obstet Gynecol, 37, 291
  146. Palluy, 1992, Hypoxia/reoxygenation stimulates endothelium to promote neutrophil adhesion, Free Radic Biol Med, 13, 21, 10.1016/0891-5849(92)90161-9 · DOI
  147. Pascoal, 1998, Preeclampsia selectively impairs endothelium-dependent relaxation and leads to oscillatory activity in small omental arteries, J Clin Invest, 101, 464, 10.1172/JCI557 · DOI
  148. Petri, 1998, Pregnancy In SLE [Review], Baillieres Clin Rheumatol, 12, 449, 10.1016/S0950-3579(98)80030-7 · DOI
  149. Pijnenborg, 1996, The placental bed, Hypertension in Pregnancy, 15, 7, 10.3109/10641959609015685 · DOI
  150. Pijnenborg, 1991, Placental bed spiral arteries in the hypertensive disorders of pregnancy, Br J Obstet Gynaecol, 98, 648, 10.1111/j.1471-0528.1991.tb13450.x · DOI · Paper page
  151. Pijnenborg, 1981, Review Article: Trophoblast invasion and the establishment of haemochorial placentation in man and laboratory animals, Placenta, 2, 71, 10.1016/S0143-4004(81)80042-2 · DOI · Paper page
  152. Powers, 1998, Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation, Am J Obstet Gynecol, 179, 1605, 10.1016/S0002-9378(98)70033-X · DOI · Paper page
  153. Powers, 1999, Methylenetetrahydrofolate reductase polymorphism, folate, and susceptibility to preeclampsia, J Soc Gynecol Investig, 6, 74, 10.1016/S1071-5576(98)00052-5 · DOI
  154. Rajakumar, 2001, Selective overexpression of the hypoxiainducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia, Biol Reprod, 64, 499, 10.1093/biolreprod/64.2.499 · DOI
  155. Rajkovic, 1997, Elevated homocyst(e)ine levels with preeclampsia, Obstet Gynecol, 90, 168, 10.1016/S0029-7844(97)00223-8 · DOI · Paper page
  156. Rauramo, 1988, Effect of exercise on placental blood flow in pregnancies complicated by hypertension, diabetes or intrahepatic cholestasis, Acta Obstet Gynecol Scand, 67, 15, 10.3109/00016348809004161 · doi:10.3109/00016348809004161
  157. Redman, 1978, Early platelet consumption in pre-eclampsia, Br Med J, 1, 467, 10.1136/bmj.1.6111.467 · DOI · Paper page
  158. Redman, 1977, Factor-VIII consumption in preeclampsia, Lancet, 2, 1249, 10.1016/S0140-6736(77)92661-7 · DOI
  159. Reister, 1999, The distribution of macrophages in spiral arteries of the placental bed in pre-eclampsia differs from that in healthy patients, Placenta, 20, 229, 10.1053/plac.1998.0373 · DOI · Paper page
  160. Roberts, 1995, Preeclampsia: not simply pregnancy-induced hypertension. [Review], Hosp Pract, 30, 25, 10.1080/21548331.1995.11443299 · doi:10.1080/21548331.1995.11443299
  161. Roberts, 1998, Endothelial dysfunction in preeclampsia, Semin Reprod Endocrinol, 16, 5, 10.1055/s-2007-1016248 · DOI · Paper page
  162. Roberts, 1992, Sera from preeclamptic women specifically activate human umbilical vein endothelial cells in vitro: morphological and biochemical evidence, Am J Reprod Immunol, 27, 101, 10.1111/j.1600-0897.1992.tb00735.x · DOI
  163. Roberts, 1999, Is oxidative stress the link in the two-stage model of pre-eclampsia?, Lancet, 354, 788, 10.1016/S0140-6736(99)80002-6 · doi:10.1016/s0140-6736(99)80002-6 · Paper page
  164. Roberts, 1993, Pre-eclampsia: More than pregnancy-induced hypertension, Lancet, 341, 1447, 10.1016/0140-6736(93)90889-O · DOI · Paper page
  165. Roberts, 1989, Preeclampsia: An endothelial cell disorder, Am J Obstet Gynecol, 161, 1200, 10.1016/0002-9378(89)90665-0 · DOI · Paper page
  166. Robertson, 1973, Placental bed vessels, Am J Obstet Gynecol, 117, 294, 10.1016/0002-9378(73)90655-8 · doi:10.1016/0002-9378(73)90655-8
  167. Robillard, 1996, Association of pregnancyinduced hypertension, pre-eclampsia, and eclampsia with duration of sexual cohabitation before conception, Lancet, 347, 619, 10.1016/S0140-6736(96)91315-X · doi:10.1016/s0140-6736(96)91315-x
  168. Robillard, 1998, Primipaternities in families—is the incidence of pregnancy-induced hypertensive disorders in multigravidas an anthropological marker of reproduction [Review], Aust NZJ Obstet Gynaecol, 38, 284, 10.1111/j.1479-828X.1998.tb03067.x · DOI
  169. Rodgers, 1988, Preeclampsia is associated with a serum factor cytotoxic to human endothelial cells [see comments], Am J Obstet Gynecol, 159, 908, 10.1016/S0002-9378(88)80169-8 · DOI · Paper page
  170. Rotmensch, 1997, Activated protein C resistance and adverse pregnancy outcome, Am J Obstet Gynecol, 177, 170, 10.1016/S0002-9378(97)70457-5 · doi:10.1016/s0002-9378(97)70457-5
  171. Rudge, 1997, Hypertensive disorders in pregnant women with diabetes mellitus, Gynecol Obstet Invest, 44, 11, 10.1159/000291401 · DOI
  172. Sacks, 1998, Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis, Am J Obstet Gynecol, 179, 80, 10.1016/S0002-9378(98)70254-6 · DOI · Paper page
  173. Sattar, 1997, Lipoprotein subfraction concentrations in preeclampsia: pathogenic parallels to atherosclerosis, Obstet Gynecol, 89, 403, 10.1016/S0029-7844(96)00514-5 · DOI · Paper page
  174. Sattar, 1997, Lipoprotein subfraction changes in normal pregnancy: threshold effect of plasma triglyceride on appearance of small, dense low density lipoprotein, J Clin Endocrinol Metab, 82, 2483, 10.1210/jc.82.8.2483 · DOI
  175. Schiff, 1992, Immunoreactive circulating endothelin-1 in normal and hypertensive pregnancies, Am J Obstet Gynecol, 166, 624, 10.1016/0002-9378(92)91688-7 · DOI
  176. Schobel, 1996, Preeclampsia—a state of sympathetic overactivity, N Engl J Med, 335, 1480, 10.1056/NEJM199611143352002 · DOI · Paper page
  177. Schobel, 1998, Hypertensive disorders of pregnancy—a dysregulation of the sympathetic nervous system, J Hypertens, 16, 569, 10.1097/00004872-199816050-00002 · DOI
  178. Schubring, 1997, Levels of leptin in maternal serum, amniotic fluid, and arterial and venous cord blood: relation to neonatal and placental weight, J Clin Endocrinol Metab, 82, 1480, 10.1210/jc.82.5.1480 · DOI · Paper page
  179. Segrest, 1994, Pathogenesis of atherosclerosis, Curr Opin Cardiol, 9, 404
  180. Senaris, 1997, Synthesis of leptin in human placenta, Endocrinology, 138, 4501, 10.1210/en.138.10.4501 · DOI
  181. Shembrey, 1995, An instructive case of abdominal pregnancy, Aust NZJ Obstet Gynaecol, 35, 220, 10.1111/j.1479-828X.1995.tb01879.x · DOI
  182. Sibai, 1986, Severe preeclampsia-eclampsia in young primigravid women: Subsequent pregnancy outcome and remote prognosis, Am J Obstet Gynecol, 155, 1011, 10.1016/0002-9378(86)90336-4 · DOI · Paper page
  183. Sibai, 1997, Risk factors associated with preeclampsia in healthy nulliparous women. The Calcium for Preeclampsia Prevention (CPEP) Study Group [see comments], Am J Obstet Gynecol, 177, 1003, 10.1016/S0002-9378(97)70004-8 · DOI · Paper page
  184. Sibai, 1995, Risk factors for preeclampsia in healthy nulliparous women: a prospective multicenter study. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units, Am J Obstet Gynecol, 172, 642, 10.1016/0002-9378(95)90586-3 · DOI · Paper page
  185. Sikorski, 1998, Pre-eclampsia—a state of sympathetic over-activity, British Journal of Obstetrics and Gynaecology, 105, 126, 10.1111/j.1471-0528.1998.tb09367.x · doi:10.1111/j.1471-0528.1998.tb09367.x
  186. Sladek, 1998, Granulated metrial gland cells contain nitric oxide synthases during pregnancy in the rat, Placenta, 19, 55, 10.1016/S0143-4004(98)90099-6 · doi:10.1016/s0143-4004(98)90099-6
  187. Smarason, 1993, The effect of placental syncytiotrophoblast microvillous membranes from normal and pre-eclamptic women on the growth of endothelial cells in vitro, British Journal of Obstetrics and Gynaecology, 100, 943, 10.1111/j.1471-0528.1993.tb15114.x · DOI · Paper page
  188. Smith, 1997, Increased incidence of preeclampsia in women conceiving by intrauterine insemination with donor versus partner sperm for treatment of primary infertility, Am J Obstet Gynecol, 177, 455, 10.1016/S0002-9378(97)70215-1 · DOI
  189. Sohda, 1997, Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia, J Med Genet, 34, 525, 10.1136/jmg.34.6.525 · DOI · Paper page
  190. Steinberg, 1995, Role of oxidized LDL and antioxidants in atherosclerosis, Advances in Experimental Medicine & Biology, 369, 39, 10.1007/978-1-4615-1957-7_5 · DOI · Paper page
  191. Stone, 1994, Risk factors for severe preeclampsia, Obstet Gynecol, 83, 357
  192. Talledo, 1968, Renin-angiotensin system in normal and toxemic pregnancies, Am J Obstet Gynecol, 100, 218, 10.1016/S0002-9378(15)33724-8 · DOI · Paper page
  193. Taylor, 1997, Review: Immunobiology of preeclampsia, Am J Reprod Immunol, 37, 79, 10.1111/j.1600-0897.1997.tb00195.x · DOI
  194. Taylor, 1991, High plasma cellular fibronectin levels correlate with biochemical and clinical features of preeclampsia but cannot be attributed to hypertension alone, Am J Obstet Gynecol, 165, 895, 10.1016/0002-9378(91)90435-T · doi:10.1016/0002-9378(91)90435-t
  195. Taylor, 1991, Growth factor activity in the blood of women in whom preeclampsia develops is elevated from early pregnancy, Am J Obstet Gynecol, 163, 1839, 10.1016/0002-9378(90)90761-U · DOI
  196. Taylor, 1990, Partial characterization of a novel growth factor from the blood of women with preeclampsia, Journal of Clinical Endocrinology & Metabolism, 70, 1285, 10.1210/jcem-70-5-1285 · DOI
  197. Taylor, 1991, Preeclamptic sera stimulate increased platelet-derived growth factor mRNA and protein expression by cultured human endothelial cells, Am J Reprod Immunol, 25, 105, 10.1111/j.1600-0897.1991.tb01075.x · doi:10.1111/j.1600-0897.1991.tb01075.x
  198. Taylor, 1990, Women with preeclampsia have higher plasma endothelin levels than women with normal pregnancies, Journal of Clinical Endocrinology Metabolism, 71, 1675, 10.1210/jcem-71-6-1675 · DOI · Paper page
  199. Teppa, 2000, Free leptin is increased in normal pregnancy and further increased in preeclampsia, Metabolism-Clinical and Experimental, 49, 1043, 10.1053/meta.2000.7707 · DOI
  200. Thorp, 1990, von Willebrand factor multimeric levels and patterns in patients with severe preeclampsia, Obstet Gynecol, 75, 163

200 of 218 shown

Cited by

See all 597

Metadata

Authors
Roberts, J. M., & Lain, K. Y.
Venue
Placenta
Publisher
Elsevier BV
Published
2002-05
Volume
23
Issue
5
Pages
359-372
ISSN
0143-4004 (ISSN-L)
DOI
10.1053/plac.2002.0819
OpenAlex
W2084586130
Cited by
597
References
6
FWCI
33.35
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Recent Insights into the Pathogenesis of Pre-eclampsia. https://app.cochat.ai/papers/10.1053/plac.2002.0819
The paper
Roberts, J. M., & Lain, K. Y. (2002). Recent Insights into the Pathogenesis of Pre-eclampsia. Placenta. https://doi.org/10.1053/plac.2002.0819

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.