Perceived distress, personality characteristics, coping strategies and psychosocial impairments in a national German multicenter cohort of patients with Crohn’s disease and ulcerative colitis: Psychosocial impairments in IBD: Data from a national German multicenter cohort
Abstract
BACKGROUND AND AIMS: This study examined differences in personality, psychological distress, and stress coping in inflammatory bowel disease (IBD) depending on type of disease and disease activity. We compared patients suffering from Crohn's disease (CD) and ulcerative colitis (UC) with controls. While the literature is replete with distinctive features of the pathogenesis of IBD, the specific differences in psychological impairments are not well studied. METHODS: In this German national multicenter study, participants were recruited from 32 centers. Two hundred ninety-seven questionnaires were included, delivering vast information on disease status and psychological well-being based on validated instruments with a total of 285 variables. RESULTS: CD patients were more affected by psychological impairments than patients suffering from UC or controls. Importantly, patients with active CD scored higher in neuroticism (p < 0.01), psychological distress (p < 0.001) and maladaptive stress coping (escape, p = 0.03; rumination, p < 0.03), but less need for social support (p = 0.001) than controls. In contrast, patients suffering from active UC showed psychological distress (p < 0.04) and maladaptive coping (avoidance, p < 0.03; escape, p = 0.01). Patients in remission seemed to be less affected. In particular, patients with UC in remission were not inflicted by psychological impairments. The group of CD patients in remission however, showed insecurity (p < 0.01) and paranoid ideation (p = 0.04). CONCLUSIONS: We identified specific aspects of psychological impairment in IBD depending on disease and disease activity. Our results underscore the need for psychological support and treatment particularly in active CD.
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A multicenter cohort study in Germany found that patients with CD were more likely to be affected by psychological disorders than those with UC or controls.
“A multicenter cohort study in Germany found that patients with CD were more likely to be affected by psychological disorders than those with UC or controls.”
From Stress triggers flare of inflammatory bowel disease in children and adults (2019) · cites this paper as [94]
Compared with healthy controls, both UC and CD patients scored higher on psychological disorders and maladaptive stress coping tests during the active phase.
“Compared with the healthy controls, both UC and CD patients scored higher on psychological disorders and maladaptive stress coping tests during the active phase.”
From Stress triggers flare of inflammatory bowel disease in children and adults (2019) · cites this paper as [94]
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- Authors
- Petruo, V., Krauss, E., Kleist, A., Hardt, J., Hake, K., Peirano, J., Krause, T., Ehehalt, R., von Arnauld de la Perriére, P., Büning, J., Treml, O., Krauss, N., Albrecht, H., Felten, G., Hermannspahn, U., Burkhardt, U., Eisold, M., Teich, N., Siegmund, B., Maaser, C., Bokemeyer, B., Baumgart, D., Neurath, M., Mudter, J., & German IBD Study Group (GISG) KND
- Affiliations
- Technische Universität Dresden (DE)
- Justus-Liebig-Universität Gießen (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University of Rostock (DE)
- Psychotherapy practice with focus on IBD, Hamburg, Germany
- Gastroenterological practice, Kassel, Germany
- Gastroenterological practice, Heidelberg, Germany
- Gastroenterological practice, Lüneburg, Germany
- University Hospital Schleswig-Holstein (DE)
- Specialized Medical Center, Hagen, Germany
- Gastroenterological Practice, Herne, Germany
- Klinikum Mittelbaden (DE)
- Gastroenterological Practice, Plauen, Germany
- Gastroenterological Practice, Moessingen, Germany
- Gastroenterological Practice, Leipzig, Germany
- Charité – Universitätsmedizin Berlin (DE)
- Klinikum Lüneburg (DE)
- University of Alberta (CA)
- ORCID
- Venue
- Zeitschrift für Gastroenterologie
- Publisher
- Georg Thieme Verlag KG
- Published
- 2019-04
- Volume
- 57
- Issue
- 04
- Pages
- 473-483
- ISSN
- 0044-2771 (ISSN-L)
- 1439-7803
- OpenAlex
- W2939156743
- Cited by
- 16
- References
- 42
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 2 · 2019: 1
- FWCI
- 1.20
- Type
- journal article
- Language
- de
- Open access
- closed
- Locations
- Zeitschrift für Gastroenterologie (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- Crohn's disease, ulcerative colitis, inflammatory bowel disease, psychological distress, personality traits, neuroticism, stress coping, maladaptive coping, psychosocial impairment, disease activity, remission, paranoid ideation, insecurity, social support
- MeSH terms
- Adaptation, Psychological, Adolescent, Adult, Aged, Aged, 80 and over, Colitis, Ulcerative, Crohn Disease, Female, Humans, Male, Middle Aged, Patients, Personality, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Stress, Psychological, Young Adult
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