Effects of a Comprehensive Lifestyle Modification Program on Quality-of-Life in Patients with Ulcerative Colitis: A Twelve-Month Follow-Up
Abstract
OBJECTIVE: To analyze the effects of a comprehensive lifestyle modification program on health-related quality-of-life, psychological distress, and clinical parameters in patients with ulcerative colitis (UC) 3- and 12 months after completion of the program. MATERIAL AND METHODS: Sixty patients with UC in clinical remission or with low disease activity were randomly assigned to an intervention group or a usual-care control group. Comprehensive lifestyle modification consisted of a structured 60-h training program over a period of 10 weeks which included stress management training, psychoeducational elements, and self-care strategies. Quality-of-life, psychological distress, and clinical disease activity were assessed with standardized questionnaires (Inflammatory Bowel Disease Questionnaire (IBDQ); the MOS Short-Form 36 (SF-36); the Brief Symptom Inventory (BSI), and the Colitis Activity Index (CAI)) at baseline, and 3 months and 12 months after comprehensive lifestyle modification. RESULTS: Three months after comprehensive lifestyle modification, patients in the intervention group showed significantly greater improvement in the SF-36 scale physical function (p=0.0175), and a significantly greater reduction in anxiety scores, measured with the BSI (p=0.0294). Use of relaxation techniques was a significant predictor of improvement in the psychological sum score after 3 months of therapy (p=0.034). Though 80% of patients with an initial IBDQ score <170 in the intervention group showed an improvement of >16 points after 3 months, no significant effects of the intervention were found on the IBDQ scales, or on clinical disease parameters, including CAI scores, self-assessed disease activity, hospitalizations, or medical consultations. CONCLUSIONS: These results are consistent with possible short-term benefits of a comprehensive lifestyle modification program on some aspects of quality-of-life and emotional well-being, but no effects were discernable 12 months after completion of therapy. Comprehensive lifestyle modification had no effect on clinical disease variables. The generalizability of these data is limited because of the inclusion of patients with a relatively low disease activity who were interested in integrative medicine.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Comprehensive Lifestyle Modification Programs aim to improve physical, psychological, and social well-being primarily through refocusing techniques within the BSRP framework.
“This approach aims to improve physical, psychological, and social well-being primarily through refocusing techniques within the BSRP framework [319,321].”
From Comprehensive review of chronic stress pathways and the efficacy of behavioral stress reduction programs (BSRPs) in managing diseases. (2024) · cites this paper as [321]
Cites
(1992) · PubMed · Cited by 33,716 · see citing works
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033 · see citing works
(2008) · Medical Entomology and Zoology · Cited by 7,477 · see citing works
MCHORNEY, C. A., JOHNE, W., & ANASTASIAE, R. (1993) · Medical Care · doi:10.1097/00005650-199303000-00006 · Cited by 6,681 · see citing works
McHorney, C. A., Ware, J. E., Rachel Lu, J. F., & Sherbourne, C. D. (1994) · Medical Care · doi:10.1097/00005650-199401000-00004 · Cited by 4,458 · see citing works
Cortisone in Ulcerative Colitis
Truelove, S. C., & Witts, L. J. (1955) · BMJ · doi:10.1136/bmj.2.4947.1041 · Cited by 2,793 · see citing works
Xu, X., Yuan, G., Li, Q., Shan, S.-L., & Jiang, S. (2012) · Hepatogastroenterology · doi:10.5754/hge12404 · Cited by 1,825 · see citing works
Rachmilewitz, D. (1989) · BMJ · doi:10.1136/bmj.298.6666.82 · Cited by 1,038 · see citing works
Comparison of scheduled and episodic treatment strategies of infliximab in Crohn’s disease
Rutgeerts, P. J., Feagan, B. G., Lichtenstein, G. R., Mayer, L., Schreiber, S., Colombel, J., Rachmilewitz, D., Wolf, D. C., Olson, A. D., Bao, W., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.014 · Cited by 942 · see citing works
SF-36, Fragebogen zum Gesundheitszustand
Bullinger, M., & Kirchberger, I. (1998) · Cited by 835 · see citing works
Bullinger, M. (1995) · Social Science & Medicine · doi:10.1016/0277-9536(95)00115-n · Cited by 763 · see citing works
Irvine, E. J., Feagan, B. G., Rochon, J., Archambault, A., Fedorak, R. N., Groll, A., Kinnear, D. G., Saibil, F. G., & McDonald, J. W. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90585-1 · Cited by 709 · see citing works
Sandborn, W. J., Feagan, B. G., Hanauer, S. B., Lochs, H. H., Löfberg, R., Modigliani, R., Present, D. H., Rutgeerts, P. J., Schölmerich, J., Stange, E. F., et al. (2002) · Gastroenterology · doi:10.1053/gast.2002.31072 · Cited by 687 · see citing works
Mittermaier, C., Dejaco, C., Waldhoer, T., Oefferlbauer-Ernst, A., Miehsler, W., Beier, M., Tillinger, W., Gangl, A., & Moser, G. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000106907.24881.f2 · Cited by 532 · see citing works
Stress and Exacerbation in Ulcerative Colitis: A Prospective Study of Patients Enrolled in Remission
Levenstein, S., Prantera, C., Varvo, V., Scribano, M. L., Andreoli, A., Luzi, C., Arcà, M., Berto, E., Milite, G., & Marcheggiano, A. (2000) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02012.x · Cited by 451 · see citing works
The Symptom Check-List-90-R (SCL-90-R): A German validation study
Schmitz, N., Hartkamp, N., Kiuse, J., Franke, G. H., Reister, G., & Tress, W. (2000) · Quality of Life Research · doi:10.1023/a:1008931926181 · Cited by 430 · cited 6× · see citing works
“With Correspondence: Jost Langhorst, MD, Chair of Complementary and Integrative Medicine, University of Duisburg-Essen, Kliniken Essen Mitte, Am Deimelsberg 34 A, DE-45276 Essen, Germany.”
MethodInfluentialPsychosocial determinants of relapse in ulcerative colitis: A longitudinal study
Bitton, A., Sewitch, M. J., Peppercorn, M. A., de B Edwardes, M. D., Shah, S., Ransil, B., & Locke, S. E. (2003) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07717.x · Cited by 226 · see citing works
Levenstein, S., Prantera, C., Varvo, V., Scribano, M. L., Berto, E., Andreoli, A., & Luzi, C. (1994) · PubMed · Cited by 188 · see citing works
Elsenbruch, S., Langhorst, J., Popkirowa, K., Müller, T., Luedtke, R., Franken, U., Paul, A., Spahn, G., Michalsen, A., Janssen, O., et al. (2005) · Psychotherapy and Psychosomatics · doi:10.1159/000086318 · Cited by 181 · see citing works
Self-citationBernklev, T., Jahnsen, J., Aadland, E., Sauar, J., Schulz, T. B., Lygren, I., Henriksen, M., Stray, N., Kjellevold, Ø., Vatn, M., et al. (2004) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310008386 · Cited by 151 · see citing works
Coping Strategies and Quality of Life of Adolescents with Inflammatory Bowel Disease
van der Zaag–Loonen, H. J., Grootenhuis, M. A., Last, B. F., & Derkx, H. H. F. (2004) · Quality of Life Research · doi:10.1023/b:qure.0000025598.89003.0c · Cited by 147 · see citing works
Waters, B. M., Jensen, L. A., & Fedorak, R. N. (2005) · Canadian Journal of Gastroenterology · doi:10.1155/2005/250504 · Cited by 138 · see citing works
Determinants of Life Satisfaction in Inflammatory Bowel Disease
Janke, K.-H., Klump, B., Gregor, M., Meisner, C., & Häuser, W. (2005) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000160809.38611.f7 · Cited by 138 · see citing works
Cross-cultural variation in disease-related concerns among patients with inflammatory bowel disease
Levenstein, S., Li, Z., Almer, S. H., Barbosa, A., Marquis, P., Moser, G., Sperber, A. D., Toner, B. B., & Drossman, D. A. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03878.x · Cited by 136 · see citing works
Evaluation of a psychological treatment for inflammatory bowel disease
Schwarz, S. P., & Blanchard, E. B. (1991) · Behaviour Research and Therapy · doi:10.1016/0005-7967(91)90045-5 · Cited by 131 · see citing works
Langhorst, J., Anthonisen, I. B., Steder-Neukamm, U., Lüdtke, R., Spahn, G., Michalsen, A., & Dobos, G. (2005) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000160771.71328.6c · Cited by 126 · see citing works
Self-citationA stress management programme for inflammatory bowel disease patients
Milne, B. J., Joachim, G., & Niedhardt, J. (1986) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.1986.tb01288.x · Cited by 118 · see citing works
Mussell, M., cker, U. B., Nagel, N., & Singer, M. V. (2004) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200412000-00007 · Cited by 117 · see citing works
The relation between daily stress and Crohn's disease
Garrett, V. D., Brantley, P. J., Jones, G. N., & McKnight, G. T. (1991) · Journal of Behavioral Medicine · doi:10.1007/bf00844770 · Cited by 112 · see citing works
Larsson, K., Sundberg Hjelm, M., Karlbom, U., Nordin, K., Anderberg, U. M., & Lööf, L. (2003) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310003309 · Cited by 106 · see citing works
Borgaonkar, M. R., Townson, G., Donnelly, M., & Irvine, E. J. (2002) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200207000-00005 · Cited by 102 · see citing works
Long-term monitoring of psychosocial stress and symptomatology in inflammatory bowel disease
Greene, B. R., Blanchard, E. B., & Wan, C. K. (1994) · Behaviour Research and Therapy · doi:10.1016/0005-7967(94)90114-7 · Cited by 100 · see citing works
Michalsen, A., Grossman, P., Lehmann, N., Knoblauch, N. T. M., Paul, A. E., Moebus, S., Budde, T., & Dobos, G. J. (2005) · Psychotherapy and Psychosomatics · doi:10.1159/000087781 · Cited by 99 · see citing works
Self-citationJantschek, G. (1998) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365529850172386 · Cited by 92 · see citing works
Smith, G. D., Watson, R. A., Roger, D., McRorie, E., Hurst, N. P., Luman, W., & Palmer, K. R. (2002) · Journal of Advanced Nursing · doi:10.1046/j.1365-2648.2002.02159.x · Cited by 89 · see citing works
Relaxation training as a treatment for chronic pain caused by ulcerative colitis
Shaw, L., & Ehrlich, A. (1987) · Pain · doi:10.1016/0304-3959(87)90043-1 · Cited by 83 · see citing works
Heightened Responses to Stressors in Patients with Inflammatory Bowel Disease
Farhadi, A., Keshavarzian, A., de Kar, L. D. V., Jakate, S. M., Domm, A., Zhang, L., Shaikh, M. W., Banan, A., & Fields, J. Z. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.50071.x · Cited by 83 · see citing works
Hoffmann, J. C., Zeitz, M., Bischoff, S. C., Brambs, H. –., Bruch, H. ‐., Buhr, H., Dignass, A. U., Fischer, I., Fleig, W. E., Fölsch, U. R., et al. (2004) · Zeitschrift für Gastroenterologie · doi:10.1055/s-2004-813510 · Cited by 77 · see citing works
The Role of Quality of Care in Health-related Quality of Life in Patients with IBD
van der Eijk, I., Vlachonikolis, I. G., Munkholm, P. S., Nijman, J., Bernklev, T., Politi, P., Odes, S. H., Tsianos, E. V., Stockbrügger, R. W., & Rüssel, M. G. (2004) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200407000-00010 · Cited by 71 · see citing works
Effect of psychotherapy and relaxation on the psychosocial and somatic course of Crohn's disease
Keller, W., Pritsch, M., von Wietersheim, J., Scheib, P., Osborn, W., Balck, F. B., Dilg, R., Schmelz-Schumacher, E., Doppl, W., Jantschek, G., et al. (2004) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(03)00122-3 · Cited by 67 · see citing works
Supportive-Expressive Group Psychotherapy for Persons with Inflammatory Bowel Disease
Maunder, R., & Esplen, M. J. (2001) · The Canadian Journal of Psychiatry · doi:10.1177/070674370104600706 · Cited by 65 · see citing works
Gender and disease activity influence health-related quality of life in inflammatory bowel diseases.
Saibeni, S., Cortinovis, I., Beretta, L., Tatarella, M., Ferraris, L., Rondonotti, E., Corbellini, A., Bortoli, A., Colombo, E., Alvisi, C., et al. (2005) · PubMed · Cited by 54 · see citing works
Health‐Related Concerns of People who Receive Psychological Support for Inflammatory Bowel Disease
Maunder, R., Rooy, E. C. D., Toner, B. B., Greenberg, G. R., Steinhart, A. H., McLeod, R. S., & Cohen, Z. (1997) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/1997/183841 · Cited by 50 · see citing works
Häuser, W., Dietz, N., Grandt, D., Steder-Neukamm, U., Janke, K.-H., Stein, U., & Stallmach, A. (2004) · Zeitschrift für Gastroenterologie · doi:10.1055/s-2004-812835 · Cited by 48 · see citing works
Bregenzer, N., Lange, A., Fürst, A., Groß, V., Schölmerich, J., & Andus, T. (2005) · Zeitschrift für Gastroenterologie · doi:10.1055/s-2004-813867 · Cited by 44 · see citing works
Leong, R. W. L., Lawrance, I. C., Ching, J. Y. L., Cheung, C. M., Fung, S. S. L., Ho, J. N. C., Philpott, J., Wallace, A. R., & Sung, J. J. �. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000043384.26092.f4 · Cited by 43 · see citing works
Psychological stress and colitis
Mayer, E. A. (2000) · Gut · doi:10.1136/gut.46.5.595 · Cited by 30 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Depression and anxiety in inflammatory bowel disease: A review of comorbidity and management
Graff, L. A., Walker, J. R., & Bernstein, C. N. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20873 · Cited by 586 · see citing works
Assche, G. V., Dignass, A. U., Bokemeyer, B., Danese, S., Gionchetti, P., Moser, G., Beaugerie, L., Gomollón, F., Häuser, W., Herrlinger, K. R., et al. (2012) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2012.09.005 · Cited by 461 · see citing works
Gracie, D. J., Irvine, A. J., Sood, R., Mikocka-Walus, A., Hamlin, P. J., & Ford, A. C. (2017) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(16)30206-0 · Cited by 271 · see citing works
Psychological issues in inflammatory bowel disease: an overview
Sajadinejad, M. S., Asgari, K., Molavi, H., Kalantari, M., & Adibi, P. (2012) · Gastroenterology Research and Practice · doi:10.1155/2012/106502 · Cited by 242 · see citing works
Labanski, A., Langhorst, J., Engler, H., & Elsenbruch, S. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104501 · Cited by 200 · see citing works
Self-citationLanghorst, J., Wulfert, H., Lauche, R., Klose, P., Cramer, H., Dobos, G., & Korzenik, J. R. (2014) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jju007 · Cited by 198 · see citing works
Self-citationPsychological interventions for treatment of inflammatory bowel disease
Timmer, A., Preiss, J. C., Motschall, E., Rücker, G., Jantschek, G., & Moser, G. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006913.pub2 · Cited by 187 · see citing works
Dignass, A. U., Preiß, J., Aust, D., Autschbach, F., Ballauff, A., Barretton, G., Bokemeyer, B., Fichtner‐Feigl, S., Hagel, S., Herrlinger, K. R., et al. (2011) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0031-1281666 · Cited by 175 · see citing works
Self-citationRandomised clinical trial: yoga vs written self‐care advice for ulcerative colitis
Cramer, H., Schäfer, M., Schöls, M., Köcke, J., Elsenbruch, S., Lauche, R., Engler, H., Dobos, G. J., & Langhorst, J. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14062 · Cited by 135 · see citing works
Self-citationGoodhand, J., Greig, F. I. S., Koodun, Y., Mcdermott, A., Wahed, M., Langmead, L., & Rampton, D. (2012) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21846 · Cited by 131 · see citing works
Inflammatory Bowel Disease: A Stressed “Gut/Feeling”
Oligschlaeger, Y., Yadati, T., Houben, T., Oliván, C. M. C., & Shiri‐Sverdlov, R. (2019) · Cells · doi:10.3390/cells8070659 · Cited by 116 · see citing works
Boye, B., Lundin, K. E. A., Jantschek, G., Leganger, S., Mokleby, K., Tangen, T., Jantschek, I., Pripp, A. H., Wojniusz, S., Dahlstroem, A., et al. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21575 · Cited by 113 · see citing works
Psychotherapy for inflammatory bowel disease: a review and update
McCombie, A. M., Mulder, R. T., & Gearry, R. B. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.02.004 · Cited by 105 · see citing works
Knowles, S. R., Monshat, K., & Castle, D. J. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e318296ae5a · Cited by 102 · see citing works
Mindfulness-Based Interventions in Inflammatory Bowel Disease
Hood, M. M., & Jedel, S. (2017) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2017.08.008 · Cited by 102 · see citing works
Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease
Filipović, B. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i13.3552 · Cited by 96 · see citing works
Casellas, F., Acosta, M. B., Iglesias, M., Robles, V., Nos, P., Aguas, M., Riestra, S., de Francisco, R., Papo, M., & Borruel, N. (2012) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e32835414b2 · Cited by 95 · see citing works
Bennebroek Evertsz', F., Sprangers, M. A. G., Sitnikova, K., Stokkers, P. C. F., Ponsioen, C. Y., Bartelsman, J. F. W. M., van Bodegraven, A. A., Fischer, S., Depla, A. C. T. M., Mallant, R. C., et al. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000227 · Cited by 84 · see citing works
Riggott, C., Mikocka-Walus, A., Gracie, D. J., & Ford, A. C. (2023) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(23)00186-3 · Cited by 83 · see citing works
A critical review of self-management and educational interventions in inflammatory bowel disease
Barlow, C., Cooke, D., Mulligan, K., Beck, E., & Newman, S. (2010) · Gastroenterology Nursing · doi:10.1097/sga.0b013e3181ca03cc · Cited by 81 · see citing works
Distance management of inflammatory bowel disease: systematic review and meta-analysis
Huang, V. W. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i3.829 · Cited by 75 · see citing works
Sleep and Inflammatory Bowel Disease: An Important Bi-Directional Relationship
Qazi, T., & Farraye, F. A. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy334 · Cited by 75 · see citing works
Shchaslyvyi, A. Y., Antonenko, S. V., & Telegeev, G. D. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21081077 · Cited by 73 · see citing works
Does psychological counseling alter the natural history of inflammatory bowel disease?
Wahed, M., Corser, M., Goodhand, J., & Rampton, D. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21098 · Cited by 69 · see citing works
Yarlas, A. S., Rubin, D. T., Panés, J., Lindsay, J. O., Vermeire, S., Bayliss, M. S., Cappelleri, J. C., Maher, S. M., Bushmakin, A. G., Chen, L. A., et al. (2018) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjy024 · Cited by 61 · see citing works
Aktualisierte S3-Leitlinie Colitis ulcerosa – Living Guideline
Kucharzik, T., Dignass, A., Atreya, R., Bokemeyer, B., Esters, P., Herrlinger, K., Kannengiesser, K., Kienle, P., Langhorst, J., Lügering, A., et al. (2020) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-1296-3444 · Cited by 48 · see citing works
Self-citationManagement of stress in inflammatory bowel disease: a therapeutic option?
Goodhand, J., Wahed, M., & Rampton, D. S. (2009) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.09.55 · Cited by 56 · see citing works
Tarricone, I., Regazzi, M. G., Bonucci, G., Rizzello, F., Carini, G., Muratori, R., Poggioli, G., & Campieri, M. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.07.001 · Cited by 53 · see citing works
The Influence of Stress on the Development and Severity of Immune-Mediated Diseases
Rampton, D. S. (2011) · Journal of Rheumatology Supplement · doi:10.3899/jrheum.110904 · Cited by 51 · see citing works
Updated S3-Guideline Ulcerative Colitis. German Society for Digestive and Metabolic Diseases (DGVS)
Kucharzik, T., Dignass, A., Atreya, R., Bokemeyer, B., Esters, P., Herrlinger, K., Kannengiesser, K., Kienle, P., Langhorst, J., Lügering, A., et al. (2019) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-0824-0861 · Cited by 42 · see citing works
The effect of psychotherapy on quality of life in IBD Patients: A systematic review
Paulides, E., Boukema, I., van der Woude, C. J., & de Boer, N. K. H. (2021) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaa144 · Cited by 47 · see citing works
Doğan, Ö. E., KARACA, K. E., Baş, M., Alan, E. H., & Çağın, Y. F. (2024) · Nutrients · doi:10.3390/nu16101504 · Cited by 50 · see citing works
Kucharzik, T., Dignass, A., Atreya, R., Bokemeyer, B., Esters, P., Herrlinger, K., Kannengiesser, K., Kienle, P., Langhorst, J., Lügering, A., et al. (2018) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-0651-8174 · Cited by 52 · see citing works
Lamers, C. R., de Roos, N. M., Heerink, H. H., van de Worp-Kalter, L. A., & Witteman, B. J. M. (2022) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izac027 · Cited by 41 · see citing works
Predictors of Health Behavior Change After an Integrative Medicine Inpatient Program
Cramer, H., Lauche, R., Moebus, S., Michalsen, A., Langhorst, J., Dobos, G., & Paul, A. E. (2013) · International Journal of Behavioral Medicine · doi:10.1007/s12529-013-9354-6 · Cited by 39 · see citing works
Self-citationLanghorst, J., Schöls, M., Cinar, Z., Eilert, R., Kofink, K., Paul, A. E., Zempel, C., Elsenbruch, S., Lauche, R., Ahmed, M., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9103087 · Cited by 37 · see citing works
Self-citationSirois, F. M., & Hirsch, J. K. (2017) · British Journal of Health Psychology · doi:10.1111/bjhp.12262 · Cited by 36 · see citing works
Aktualisierte S3-Leitlinie Colitis ulcerosa (Version 6.2)
Kucharzik, T., Dignass, A., Atreya, R., Bokemeyer, B., Esters, P., Herrlinger, K., Kannengiesser, K., Kienle, P., Langhorst, J., Lügering, A., et al. (2024) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-2271-0994 · Cited by 37 · see citing works
Self-citationLifestyle medicine for anxiety symptoms: A meta-analysis of randomized controlled trials
Wong, V. W.-H., Ho, F. Y., Shi, N.-K., Sarris, J. J., Ng, C. H., & Tam, O. K.-Y. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.04.151 · Cited by 32 · see citing works
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?
Sudhakar, P., Wellens, J., Verstockt, B., Ferrante, M., Sabino, J., & Vermeire, S. (2022) · Gut · doi:10.1136/gutjnl-2022-328221 · Cited by 35 · see citing works
Tu, W., Xu, G., & Du, S. (2015) · Journal of Clinical Nursing · doi:10.1111/jocn.12851 · Cited by 34 · see citing works
Kucharzik, T., Dignass, A., Atreya, R., Bokemeyer, B., Esters, P., Herrlinger, K., Kannengiesser, K., Kienle, P., Langhorst, J., Lügering, A., et al. (2023) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-2060-0935 · Cited by 24 · see citing works
Self-citationBertomoro, P., Renna, S., Cottone, M., Riegler, G., Bossa, F., A, G. L., Pastorelli, L., Papi, C., Castiglione, F., Angelucci, E., et al. (2010) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2009.12.009 · Cited by 30 · see citing works
Joos, S. (2011) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-011-0758-3 · Cited by 30 · see citing works
Mind–Body Interventions for Pediatric Inflammatory Bowel Disease
Yeh, A. M., Wren, A. A., & Golianu, B. J. (2017) · Children · doi:10.3390/children4040022 · Cited by 30 · see citing works
Kanitz, J. L., Pretzer, K., Reif, M., Voss, A., Brand, R., Warschburger, P., Längler, A., Henze, G., & Seifert, G. (2011) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2011.06.008 · Cited by 28 · see citing works
High Demand for Psychotherapy in Patients with Inflammatory Bowel Disease
Klag, T., Mazurak, N., Fantasia, L., Schwille‐Kiuntke, J., Kirschniak, A., Falch, C., Goetz, M., Malek, N. P., Enck, P., & Wehkamp, J. (2017) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000001216 · Cited by 28 · see citing works
Psychological mediators of psychological distress and quality of life in inflammatory bowel disease
Kantidakis, J. D., Moulding, R., & Knowles, S. R. (2021) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2021.110596 · Cited by 26 · see citing works
Lauche, R., Cramer, H., Moebus, S., Paul, A. E., Michalsen, A., Langhorst, J., & Dobos, G. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/875874 · Cited by 26 · see citing works
Self-citationAn Integrative Day Care Clinic for chronically ill patients: Concept and case presentation
Paul, A. E., Lauche, R., Cramer, H., Altner, N., Langhorst, J., & Dobos, G. J. (2012) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2012.07.980 · Cited by 25 · see citing works
Self-citationA Systematic Review of Self-Management Interventions for Patients with Inflammatory Bowel Disease
Iizawa, M., Hirose, L., Nunotani, M., Nakashoji, M., Tairaka, A., & Fernandez, J. L. (2023) · Inflammatory Intestinal Diseases · doi:10.1159/000530021 · Cited by 23 · see citing works
Gettigan, N. M., Allen, K., Saeidi, R., Toole, A., & Boland, K. (2023) · International Journal of Colorectal Disease · doi:10.1007/s00384-023-04437-2 · Cited by 21 · see citing works
Schlee, C., Uecker, C., Bauer, N., Koch, A. K., & Langhorst, J. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03478-w · Cited by 20 · see citing works
Self-citationAssche, G. V., Dignass, A. U., Bokemeyer, B., Danese, S., Gionchetti, P., Moser, G., Beaugerie, L., Gomollón, F., Häuser, W., Herrlinger, K. R., et al. (2012) · Cited by 20 · see citing works
Aktualisierte S3-Leitlinie Colitis ulcerosa
Kucharzik, T., Dignass, A., Atreya, R., Bokemeyer, B., Esters, P., Herrlinger, K., Kannengiesser, K., Kienle, P., Langhorst, J., Lügering, A., et al. (2019) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-1015-7265 · Cited by 11 · see citing works
Self-citationHaapamäki, J., Heikkinen, E., Sipponen, T. M., Roine, R. P., & Arkkila, P. E. T. (2018) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2018.1500639 · Cited by 18 · see citing works
The impact of eurythmy therapy on fatigue in healthy adults—A controlled trial
Kanitz, J. L., Pretzer, K., Reif, M., Witt, K., Reulecke, S., Voss, A., Längler, A., Henze, G., & Seifert, G. (2012) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2012.02.006 · Cited by 17 · see citing works
Petruo, V., Krauss, E., Kleist, A., Hardt, J., Hake, K., Peirano, J., Krause, T., Ehehalt, R., von Arnauld de la Perriére, P., Büning, J., et al. (2019) · Zeitschrift für Gastroenterologie · doi:10.1055/a-0838-6371 · Cited by 16 · see citing works
Jordan, C., Hayee, B., & Chalder, T. (2019) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2326 · Cited by 14 · see citing works
Koch, A. K., Schöls, M., Haller, H., Anheyer, D., Cinar, Z., Eilert, R., Kofink, K., Engler, H., Elsenbruch, S., Cramer, H., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10215070 · Cited by 14 · see citing works
Self-citationComplementary and Integrative Gastroenterology
Korzenik, J. R., Koch, A. K., & Langhorst, J. (2017) · Medical Clinics of North America · doi:10.1016/j.mcna.2017.04.009 · Cited by 13 · see citing works
Self-citationGravina, A. G., Pellegrino, R., Palladino, G., Mazzarella, C., Federico, P., Arboretto, G., D'Onofrio, R., Olivieri, S., Zagaria, G., Durante, T., et al. (2023) · Brain-Apparatus Communication A Journal of Bacomics · doi:10.1080/27706710.2023.2181101 · Cited by 13 · see citing works
Parian, A. M., Mullin, G. E., Langhorst, J., & Brown, A. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35868-2.00050-5 · Cited by 14 · see citing works
Self-citationGold, S. L., Chiew, B. A., Rajagopalan, V., & Lavallee, C. M. (2023) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwad029 · Cited by 11 · see citing works
Introducing integrative integrated migraine care (IIMC): A model and case presentation
Lauche, R., Cramer, H., Paul, A., Dobos, G., & Rampp, T. (2011) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2011.11.005 · Cited by 11 · see citing works
Self-citationPsychological interventions for treatment of inflammatory bowel disease
Tiles-Sar, N., Neuser, J., de Sordi, D., Baltes, A., Preiß, J., Moser, G., & Timmer, A. (2025) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006913.pub3 · Cited by 12 · see citing works
Bauer, N., Löffler, C., Öznur, Ö., Uecker, C., Keil, T. O. P., & Langhorst, J. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.960301 · Cited by 10 · see citing works
Self-citationYarlas, A. S., Yen, L., & Hodgkins, P. (2014) · Quality of Life Research · doi:10.1007/s11136-014-0797-2 · Cited by 9 · see citing works
Fábián, A., Rutka, M., Ferenci, T., Bor, R., Bálint, A., Farkas, K., Milassin, Á., Szántó, K. J., Lénárt, Z., Nagy, F. T., et al. (2018) · Gastroenterology Research and Practice · doi:10.1155/2018/9137805 · Cited by 8 · see citing works
Tamara, V. D. S. (2015) · Gastroenterology & Hepatology Open Access · doi:10.15406/ghoa.2015.02.00038 · Cited by 8 · see citing works
Cámara, R. J. A., Begré, S., & von Känel, R. (2010) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2010.56.2.116 · Cited by 8 · see citing works
Regev, S., Goren, G., Slonim‐Nevo, V., Schwartz, D., Friger, M. D., Sergienko, R., Greenberg, D., Monsonego, A., Nemirovsky, A., Odes, S., et al. (2023) · Mindfulness · doi:10.1007/s12671-023-02220-6 · Cited by 6 · see citing works
The Potential Benefits of Exercise in Managing Inflammatory Bowel Disease: A Systematic Review
Sabir, G., Abdelhady, H. A., Abakar, A. O., Gangavarapu, R. R., Mahmud, S. A., Manandhar, A., & Malasevskaia, I. A. (2024) · Cureus · doi:10.7759/cureus.68948 · Cited by 6 · see citing works
Implications of Corporate Yoga: A Review
Bhandari, R. B., Churna, B., Acharya, B., Pandya, P., Singh, K., Vinod, K., & Ganesh, D. (2012) · InTech eBooks · doi:10.5772/36657 · Cited by 6 · see citing works
Öznur, Ö., Utz, S., Schlee, C., & Langhorst, J. (2025) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2025.101006 · Cited by 4 · see citing works
Self-citationAssche, G. V., Dignass, A. U., Bokemeyer, B., Danese, S., Gionchetti, P., Moser, G., Beaugerie, L., Gomollón, F., Häuser, W., Herrlinger, K. R., et al. (2015) · Revista de Gastroenterología de México · doi:10.1016/j.rgmx.2014.10.008 · Cited by 4 · see citing works
Psychological and Social Aspects
Levenstein, S., & Varvo, V. (2010) · Springer eBooks · doi:10.1007/978-88-470-1472-5_26 · Cited by 4 · see citing works
Langhorst, J., & Lauche, R. (2014) · Digestion · doi:10.1159/000357368 · Cited by 4 · see citing works
Self-citationLauche, R., Lange, S., Cramer, H., Wagner, K., Esch, T., Langhorst, J., Dobos, G. J., & Paul, A. (2012) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2012.10.007 · Cited by 3 · see citing works
Self-citationMedicina moderna: rumo à prevenção, à cura, ao bem-estar e à longevidade
Singh, A. R. (2010) · Revista Latinoamericana de Psicopatologia Fundamental · doi:10.1590/s1415-47142010000200008 · Cited by 3 · see citing works
Aktualisierte S3-Leitlinie Colitis ulcerosa (Version 7.0)
Blumenstein, I., Schnoy, E., Atreya, R., Bettenworth, D., de Laffolie, J., Kaltz, B., Kienle, P., Langhorst, J., Maaser, C., Ockenga, J., et al. (2026) · Zeitschrift für Gastroenterologie · doi:10.1055/a-2769-2192 · Cited by 2 · see citing works
Self-citationZare, F., Ramezankhani, A., Ghaffari, M., & Yarmohammadi, S. (2022) · ranian Journal of Health Education and Health Promotion · doi:10.52547/ijhehp.10.1.93 · Cited by 2 · see citing works
Lifestyle Intervention Modulates the CD4+ T Cell Profile in the Blood of Crohn’s Disease Patients
Mekes-Adamczyk, A., Gausmann, N., Öznur, Ö., Pfuhlmann, K., Dziobaka, J., Buer, J., Langhorst, J., & Westendorf, A. M. (2024) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izae154 · Cited by 2 · see citing works
Self-citationFactors related to Quality of Life of Patients with Ulcerative Colitis
Yoo, Y., Chung, M.-Y., & Cho, O. (2014) · Korean Journal of Adult Nursing · doi:10.7475/kjan.2014.26.2.129 · Cited by 1 · see citing works
Cramer, H., Lauche, R., Klose, P., Dobos, G. J., & Langhorst, J. (2014) · Complementary Medicine Research · doi:10.1159/000358577 · Cited by 1 · see citing works
Self-citationAssche, G. V., Dignass, A. U., Bokemeyer, B., Danese, S., Gionchetti, P., Moser, G., Beaugerie, L., Gomollón, F., Häuser, W., Herrlinger, K. R., et al. (2016)
The Different Drummer: Non-traditional Therapeutic Approaches
Yen, E. F. (2017) · Clinical gastroenterology · doi:10.1007/978-3-319-53763-4_12
Koch, A. K., & Langhorst, J. (2018) · Zeitschrift für Komplementärmedizin · doi:10.1055/a-0602-1129
Self-citationGracie, D. J. (2018) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Factors related to Quality of Life of Patients with Ulcerative Colitis
Cho, C., Ok-Hee, Yoo, Yang-Sook, Chung, & Mi-young (2015) · 성인간호학회 학술대회
Mind-Body Medicine in Children and Adolescents
McClafferty, H. H. (2017) · MDPI eBooks · doi:10.3390/books978-3-03842-529-8
Salud mental y enfermedad inflamatoria intestinal
Muñoz, T. M. (2025) · Diversitas · doi:10.15332/22563067.11084
Qi-wen, F., Jiang, Y.-L., Ge, X.-Y., & Yang, J.-H. (2026) · World Journal of Psychiatry · doi:10.5498/wjp.119197
- Authors
- Langhorst, J., Mueller, T., Luedtke, R., Franken, U., Paul, A., Michalsen, A., Schedlowski, M., Dobos, G. J., & Elsenbruch, S.
- Affiliations
- Kliniken Essen-Mitte (DE)
- ETH Zurich (CH)
- Essen University Hospital (DE)
- Corresponding author
- Langhorst, Jost
- Venue
- Scandinavian Journal of Gastroenterology
- Publisher
- Informa UK Limited
- Published
- 2007-01
- Volume
- 42
- Issue
- 6
- Pages
- 734-745
- ISSN
- 0036-5521 (ISSN-L)
- 1502-7708
- OpenAlex
- W2048545464
- Cited by
- 94
- References
- 49
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 5 · 2023: 7 · 2022: 7 · 2021: 2 · 2020: 3 · 2019: 5 · 2018: 8 · 2017: 12 · 2016: 1 · 2015: 4 · 2014: 7 · 2013: 3 · 2012: 9
- FWCI
- 1.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scandinavian Journal of Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Surgery › Anorectal Disease Treatments and Outcomes
- Keywords
- ulcerative colitis, lifestyle modification, health-related quality of life, psychological distress, anxiety, stress management training, psychoeducation, self-care strategies, relaxation techniques, integrative medicine, disease activity, inflammatory bowel disease
- MeSH terms
- Adult, Colitis, Ulcerative, Female, Follow-Up Studies, Humans, Life Style, Male, Middle Aged, Quality of Life, Self Care, Stress, Psychological
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review