Cardiovascular complications of cocaine use
Abstract
The deaths of several celebrities in recent years in association with the nontherapeutic use of cocaine have focused widespread attention on the problem of cocaine abuse. In 1999, an estimated 25 million Americans admitted that they had used cocaine at least once; 3.7 million had used it within the previous year; and 1.5 million were current users. During the same year, cocaine was mentioned in 30 percent of all drug-related visits to emergency departments.1 Cocaine is the most commonly used illicit drug among subjects seeking care in hospital emergency departments or drug-treatment centers. In addition, it is the most frequent . . .
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Stimulants such as caffeine and nicotine, or the use of illicit drugs (cocaine, heroin, amphetamines, LSD, synthetic drugs, cannabis, etc.) can lead to sympathetic hyperactivation and sinus tachycardia, even in young subjects without heart disease.
“Likewise, stimulants such as caffeine and nicotine, or the use of illicit drugs (cocaine, heroin, amphetamines, LSD, synthetic drugs, cannabis, etc.) can lead to sympathetic hyperactivation and sinus tachycardia, even in young subjects without heart disease.41,42”
From Management of patients with palpitations: a position paper from the European Heart Rhythm Association (2011) · cites this paper as [42]
It is not always possible to establish a definite cause of palpitations; often, only a likely cause can be given, and, in some cases, several possible causes have to be taken into consideration.
“Indeed, it is not always possible to establish a definite cause of palpitations; often, only a likely cause can be given, and, in some cases, several possible causes have to be taken into consideration.8,42”
From Management of patients with palpitations: a position paper from the European Heart Rhythm Association (2011) · cites this paper as [42]
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- Authors
- Lange, R. A., & Hillis, L. D.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- ORCID
- Lange, Richard A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2001-08-02
- Volume
- 345
- Issue
- 5
- Pages
- 351-358
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2338565293
- Cited by
- 810
- References
- 176
- Citations by year
- 2026: 15 · 2025: 13 · 2024: 11 · 2023: 23 · 2022: 29 · 2021: 17 · 2020: 22 · 2019: 27 · 2018: 23 · 2017: 18 · 2016: 24 · 2015: 46 · 2014: 41 · 2013: 34 · 2012: 38
- FWCI
- 26.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Demography › Youth, Drugs, and Violence
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
- Keywords
- cocaine use, cardiovascular complications, cocaine abuse, cocaine-related deaths, emergency department visits, illicit drug use, drug-related hospitalizations
- MeSH terms
- Ethanol, Aortic Dissection, Aortic Aneurysm, Arrhythmias, Cardiac, Cocaine, Drug Synergism, Endocarditis, Heart Diseases, Humans, Myocardial Infarction, Smoking, Myocardial Ischemia
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