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Initial Management of Glycemia in Type 2 Diabetes Mellitus
Abstract
An asymptomatic 45-year-old Hispanic man has a fasting plasma glucose level of 142 mg per deciliter (7.9 mmol per liter) on initial evaluation and 139 mg per deciliter (7.7 mmol per liter) on reevaluation. Other than a steady gain in weight since college and borderline hypertension, his medical history is unremarkable. He is 175 cm (5 ft 9 in.) tall and weighs 95 kg (209 lb; body-mass index, 31.2), and his blood pressure is 138/88 mm Hg. Physical examination is notable only for abdominal obesity and absent ankle reflexes. How should this patient be treated?
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“inflammation and thrombosis[75]”
From Metformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical Trial (2016) · cites this paper as [75]
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Metadata
- Authors
- Nathan, D. M.
- Affiliations
- Harvard University (US)
- Corresponding author
- Nathan, David M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2002-10-24
- Volume
- 347
- Issue
- 17
- Pages
- 1342-1349
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2090609048
- Cited by
- 359
- References
- 57
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 6 · 2020: 6 · 2019: 8 · 2018: 9 · 2017: 13 · 2016: 13 · 2015: 7 · 2014: 20 · 2013: 16 · 2012: 15
- FWCI
- 14.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- type 2 diabetes, glycemic control, initial management, fasting blood glucose, obesity, borderline hypertension, Hispanic patients, weight gain
- MeSH terms
- Combined Modality Therapy, Diabetes Mellitus, Diabetes Mellitus, Type 2, Drug Therapy, Combination, Humans, Hyperglycemia, Hypoglycemic Agents, Male, Middle Aged, Obesity, Weight Loss, Practice Guidelines as Topic
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