Cited by 1,286T-cell and B-cell ImmunologyImmune responses and vaccinationsImmunotherapy and Immune Responses

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Duration of Humoral Immunity to Common Viral and Vaccine Antigens

Open access

Amanna, Ian J., Carlson, Nichole E., Slifka, Mark K.·2007·New England Journal of Medicine

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Maintenance of long-term antibody responses is critical for protective immunity against many pathogens. However, the duration of humoral immunity and the role played by memory B cells remain poorly defined. METHODS: We performed a longitudinal analysis of antibody titers specific for viral antigens (vaccinia, measles, mumps, rubella, varicella-zoster virus, and Epstein-Barr virus) and nonreplicating antigens (tetanus and diphtheria) in 45 subjects for a period of up to 26 years. In addition, we measured antigen-specific memory B cells by means of limiting-dilution analysis, and we compared memory B-cell frequencies to their corresponding serum antibody levels. RESULTS: Antiviral antibody responses were remarkably stable, with half-lives ranging from an estimated 50 years for varicella-zoster virus to more than 200 years for other viruses such as measles and mumps. Antibody responses against tetanus and diphtheria antigens waned more quickly, with estimated half-lives of 11 years and 19 years, respectively. B-cell memory was long-lived, but there was no significant correlation between peripheral memory B-cell numbers and antibody levels for five of the eight antigens tested. CONCLUSIONS: These studies provide quantitative analysis of serologic memory for multiple antigens in subjects followed longitudinally over the course of more than one decade. In cases in which multiple exposures or repeated vaccinations were common, memory B-cell numbers did not correlate with antibody titers. This finding suggests that peripheral memory B cells and antibody-secreting plasma cells may represent independently regulated cell populations and may play different roles in the maintenance of protective immunity.

Integrity signals

Registry

Crossref · 10.1056/nejmoa066092

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Adjusting for multiple testing—when and how?
Bender, R., & Lange, S. (2001) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00314-0 · Cited by 3,168
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
Edwards, J. C. W., Szczepański, L., Szechiński, J., Filipowicz-Sosnowska, A., Emery, P., Close, D. R., Stevens, R. M., & Shaw, T. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032534 · Cited by 2,623
Immunological memory and protective immunity: understanding their relation
Ahmed, R., & Gray, D. (1996) · Science · doi:10.1126/science.272.5258.54 · Cited by 1,775
Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells
Bernasconi, N. L., Traggiai, E., & Lanzavecchia, A. (2002) · Science · doi:10.1126/science.1076071 · Cited by 1,304
Humoral Immunity Due to Long-Lived Plasma Cells
Slifka, M. K., Antia, R., Whitmire, J. K., & Ahmed, R. (1998) · Immunity · doi:10.1016/s1074-7613(00)80541-5 · Cited by 1,249
Self-citation
Competence and competition: the challenge of becoming a long-lived plasma cell
Radbruch, A., Muehlinghaus, G., Luger, E., Inamine, A., Smith, K. G. C., Dörner, T., & Hiepe, F. (2006) · Nature reviews. Immunology · doi:10.1038/nri1886 · Cited by 1,033
Duration of antiviral immunity after smallpox vaccination
Hammarlund, E., Lewis, M. W., Hansen, S. G., Strelow, L. I., Nelson, J. A., Sexton, G. J., Hanifin, J. M., & Slifka, M. K. (2003) · Nature Medicine · doi:10.1038/nm917 · Cited by 946
Self-citation
Lifetime of plasma cells in the bone marrow
Manz, R. A., Thiel, A., & Radbruch, A. (1997) · Nature · doi:10.1038/40540 · Cited by 866
Cutting edge: long-term B cell memory in humans after smallpox vaccination
Crotty, S., Felgner, P., Davies, H., Glidewell, J., Villarreal, L., & Ahmed, R. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.10.4969 · Cited by 695
Measles Antibody: Reevaluation of Protective Titers
Chen, R. T., Markowitz, L. E., Albrecht, P. G., Stewart, J. A., MOFENSON, L. M., Preblud, S. R., & Orenstein, W. A. (1990) · The Journal of Infectious Diseases · doi:10.1093/infdis/162.5.1036 · Cited by 606

Flagged first, then by citations

Show all 38 references

Research works printed but not linked: 3

Bojlen K, 1955, Dan Med Bull, 2, 70
Wolters KL, 1942, Zeitschrift fur Hyeitschrift, 124, 326
Slifka MK. Mechanisms of antiviral immunity: studies on recombinant Listeria monocytogenes as a vaccine for inducing protective CTL memory and analysis of long-term antibody production after acute LCMV infection. Los Angeles: University of California, Los Angeles, 1996 (dissertation).

Sorted by citations

Items 701–800 of 1,002

Head-to-Head Comparison of Modular Vaccines Developed Using Different Capsid Virus-Like Particle Backbones and Antigen Conjugation Systems
Fredsgaard, L., Goksøyr, L., Thrane, S., Aves, K.-L., Theander, T. G., & Sander, A. F. (2021) · Vaccines · doi:10.3390/vaccines9060539 · Cited by 13
Increased incidence of dog-bite injuries after the Fukushima nuclear accident
Mori, J., Tsubokura, M., Sugimoto, A., Tanimoto, T. E., Kami, M., Oikawa, T., & Kanazawa, Y. (2013) · Preventive Medicine · doi:10.1016/j.ypmed.2013.06.013 · Cited by 13
Genome-Wide Analysis of T Cell Responses during Acute and Latent Simian Varicella Virus Infections in Rhesus Macaques
Haberthur, K., Kraft, A., Arnold, N. D., Park, B. S., Meyer, C., Asquith, M. J., Dewane, J., & Messaoudi, I. (2013) · Journal of Virology · doi:10.1128/jvi.01809-13 · Cited by 13
Two Closely Related Env Antigens from the Same Patient Elicited Different Spectra of Neutralizing Antibodies against Heterologous HIV-1 Isolates
Vaine, M., Duenas-Decamp, M. J., Peters, P. J., Liu, Q., Arthos, J. A., Wang, S., Clapham, P. R., & Lu, S. (2011) · Journal of Virology · doi:10.1128/jvi.00081-11 · Cited by 13
Introduction to Viruses and Viral Diseases
Chappell, J. D., & Dermody, T. S. (2010) · Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases · doi:10.1016/b978-0-443-06839-3.00132-6 · Cited by 13
Omicron variants escape the persistent SARS-CoV-2-specific antibody response in 2-year COVID-19 convalescents regardless of vaccination
Wang, M., Zhou, B., Fan, Q., Zhou, X., Liao, X., Lin, J., Ma, Z., Dong, J., Wang, H., Ge, X., et al. (2022) · Emerging Microbes & Infections · doi:10.1080/22221751.2022.2151381 · Cited by 12
Follow-up after infectious mononucleosis in search of serological similarities with presymptomatic multiple sclerosis
Jons, D., Berg, L. P., Sundström, P., Haghighi, S., Axelsson, M., Thulin, M., Bergström, T. B., & Andersen, O. (2021) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2021.103288 · Cited by 12
A Thermal-Stable Protein Nanoparticle That Stimulates Long Lasting Humoral Immune Response
Wong, T., Liou, G., & Kan, M.-C. (2023) · Vaccines · doi:10.3390/vaccines11020426 · Cited by 12
Changes in measles seroepidemiology of healthcare workers in southern Taiwan
Ho, T., Wang, S.-M., WANG, L. R., & LIU, C. C. (2011) · Epidemiology and Infection · doi:10.1017/s0950268811000598 · Cited by 12
Optimisation of ex vivo memory B cell expansion/differentiation for interrogation of rare peripheral memory B cell subset responses
Muir, L., McKay, P. F., Petrova, V. N., Victorovich, K. O., Kratochvil, S., Pinder, C. L., Kellam, P., & Shattock, R. J. (2017) · Wellcome Open Research · doi:10.12688/wellcomeopenres.11386.1 · Cited by 13
Do plasma cells contribute to the determination of their lifespan?
Tarlinton, D. M. (2020) · Immunology and Cell Biology · doi:10.1111/imcb.12346 · Cited by 12
Idiotype/anti-idiotype antibodies: as a glorious savior in COVID-19 pandemics
Naveed, A., Naz, D., & Rahman, S. U. (2021) · Translational Medicine Communications · doi:10.1186/s41231-021-00097-y · Cited by 12
Elucidating T Cell and B Cell Responses to SARS-CoV-2 in Humans: Gaining Insights into Protective Immunity and Immunopathology
Khanolkar, A. (2021) · Cells · doi:10.3390/cells11010067 · Cited by 12
Evaluation of the Persistence of Vaccine-Induced Protection with Human Vaccines
Vidor, E. J. (2009) · Journal of Comparative Pathology · doi:10.1016/j.jcpa.2009.10.021 · Cited by 12
Persistence of Diarrheal Pathogens Is Associated with Continued Recruitment of Plasmablasts in the Circulation
Kantele, A. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/279206 · Cited by 12
Relationship between Malaria Incidence and IgG Levels to Plasmodium falciparum Merozoite Antigens in Malian Children: Impact of Hemoglobins S and C
Miura, K., Diakité, M., Diouf, A., Doumbia, S., Konate, D. S., Keita, A. S., Moretz, S. E., Tullo, G., Zhou, H., Lopera-Mesa, T. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060182 · Cited by 12
Effects of skeletal unloading on the bone marrow antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice
Rettig, T. A., Nishiyama, N. C., Pecaut, M. J., & Chapes, S. K. (2019) · Life Sciences in Space Research · doi:10.1016/j.lssr.2019.06.001 · Cited by 13
Serum IgG levels to Epstein-Barr and measles viruses in patients with multiple sclerosis during natalizumab and interferon beta treatment
Berg, L. P., Eriksson, M., Longhi, S., Kockum, I. S., Warnke, C., Thomsson, E., Bäckström, M., Olsson, T. P., Fogdell‐Hahn, A., & Bergström, T. B. (2022) · BMJ Neurology Open · doi:10.1136/bmjno-2022-000271 · Cited by 12
Adaptive Immune Responses
Kemball, C. C., Fujinami, R. S., & Whitton, J. L. (2014) · ASM Press eBooks · doi:10.1128/9781555816698.ch19 · Cited by 12
Analysis of cell-mediated immune responses in support of dengue vaccine development efforts
Rothman, A. L., Currier, J. R., Friberg, H., & Mathew, A. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.09.104 · Cited by 11
Early Diagnosis of Pathogen Infection by Cell-Based Activation Immunoassay
Bar‐Haim, E., Rotem, S., Elia, U., Bercovich-Kinori, A., Israeli, M., Cohen-Gihon, I., Israeli, O., Noam Erez, A., Achdout, H., Zauberman, A., et al. (2019) · Cells · doi:10.3390/cells8090952 · Cited by 11
Thymus antibody-secreting cells possess an interferon gene signature and are preferentially expanded in young female mice
Pioli, K. T., Lau, K. H., & Pioli, P. D. (2023) · iScience · doi:10.1016/j.isci.2023.106223 · Cited by 11
Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus
Weiß, S., Holtfreter, S., Meyer, T. C., Schmiedeke, F., Cammann, C., Dörr, M., Felix, S. B., Grabe, H. J., Homuth, G., Köhler, C., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1229562 · Cited by 11
Impaired antibody memory to varicella zoster virus in HIV‐infected children: low antibody levels and avidity*
L’Huillier, A. G., Ferry, T., Courvoisier, D. S., Aebi, C., Jj, C., Kind, C., Rudin, C., Nadal, D., Hirschel, B. J., Sottas, C. C., et al. (2011) · HIV Medicine · doi:10.1111/j.1468-1293.2011.00936.x · Cited by 11
Large decrease of anti-tetanus anatoxin and anti-pneumococcal antibodies at one year after renal transplantation
Broeders, E. N., Wissing, K. M., Ghisdal, L., Lemy, A., Hoang, A.-D., Vereerstraeten, P., Mascart, F., & Abramowicz, D. (2012) · Clinical Nephrology · doi:10.5414/cn107779 · Cited by 11
Seroepidemiology of Varicella Zoster Virus among children, adolescents and medical students in a referral children medical center, Tehran, Iran.
Pourakbari, B., Shahbaznezhad, L., Parvaneh, N., Nikkhah, S., Mahmoudi, S., Teymuri, M., Alyari, A., & Mamishi, S. (2012) · Europe PMC (PubMed Central) · Cited by 11
Kinetics of Humoral and Memory B Cell Response Induced by the Plasmodium falciparum 19-Kilodalton Merozoite Surface Protein 1 in Mice
Kafuye-Mlwilo, M. Y., Mukherjee, P., & Chauhan, V. S. (2011) · Infection and Immunity · doi:10.1128/iai.05188-11 · Cited by 11
Predictors of durable immune responses six months after the last vaccination in preventive HIV vaccine trials
Huang, Y., Zhang, L., Janes, H., Frahm, N., Isaacs, A., Kim, J. H., Montefiori, D. C., McElrath, M. J., Tomaras, G. D., & Gilbert, P. B. (2017) · Vaccine · doi:10.1016/j.vaccine.2016.09.053 · Cited by 11
Initiation, Persistence and Exacerbation of Food Allergy
Jiménez‐Saiz, R., Chu, D. K., Waserman, S., & Jordana, M. (2017) · Birkhäuser advances in infectious diseases · doi:10.1007/978-3-319-69968-4_7 · Cited by 11
Predictors of the immune response to booster immunisation against tetanus in Czech healthy adults
Petráš, M., & Oleár, V. (2018) · Epidemiology and Infection · doi:10.1017/s095026881800242x · Cited by 11
COVID‐19, varying genetic resistance to viral disease and immune tolerance checkpoints
Goodnow, C. C. (2020) · Immunology and Cell Biology · doi:10.1111/imcb.12419 · Cited by 15
Physical ‘strength’ of the multi‐protein chain connecting immune cells: Does the weakest link limit antibody affinity maturation?
Desikan, R., Antia, R., & Dixit, N. M. (2021) · BioEssays · doi:10.1002/bies.202000159 · Cited by 11
Immune Responses to Varicella-Zoster Virus Vaccines
Levin, M. J., & Weinberg, A. (2021) · Current topics in microbiology and immunology · doi:10.1007/82_2021_245 · Cited by 11
Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity
Muñoz-Alía, M. Á., Nace, R. A., Balakrishnan, B., Zhang, L., Packiriswamy, N., Singh, G., Warang, P., Mena, I., Narjari, R., Vandergaast, R., et al. (2024) · mBio · doi:10.1128/mbio.02928-23 · Cited by 12
Ex Vivo Analysis of Human Memory B Lymphocytes Specific for A and B Influenza Hemagglutinin by Polychromatic Flow-Cytometry
Bardelli, M., Alleri, L., Angiolini, F., Buricchi, F., Tavarini, S., Sammicheli, C., Nuti, S., Degl'Innocenti, E., Isnardi, I., Fragapane, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070620 · Cited by 11
Epstein–Barr Virus, but Not Cytomegalovirus, Latency Accelerates the Decay of Childhood Measles and Rubella Vaccine Responses—A 10-Year Follow-up of a Swedish Birth Cohort
Lasaviciute, G., Björkander, S., Carvalho‐Queiroz, C., Myrberg, I. H., Nussbaum, B., Nilsson, C. A., Bemark, M., Nilsson, A., Sverremark‐Ekström, E., & Saghafian‐Hedengren, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01865 · Cited by 11
Determination of threshold value of protective level of class G antibodies to SARS-COV‑2 in late phase of immune response in COVID‑19 convalescents
Александровна, А. Н., Алексеевна, К. Н., Davydova, D. I., Aleksanin, S. S., & Rybnikov, V. Y. (2022) · Medical alphabet · doi:10.33667/2078-5631-2022-6-11-16 · Cited by 10
Prediction of long-term humoral response induced by the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo vaccine against Ebola
Alexandre, M., Prague, M., McLean, C. M., Bockstal, V., Douoguih, M., Thiébaut, R., Consortia, F. T. E. 1. A. E. 2., Effelterre, T. P. V., Solforosi, L., Bockstal, V., et al. (2023) · npj Vaccines · doi:10.1038/s41541-023-00767-y · Cited by 11
New insights into the mechanisms regulating plasma cell survival and longevity
Khamyath, M., Melhem, H., Balabanian, K., & Espéli, M. (2024) · Current Opinion in Immunology · doi:10.1016/j.coi.2024.102442 · Cited by 10
Persistent IgG1 clones dominate and personalize the plasma antibody repertoire
van Rijswijck, D. M. H., Bondt, A., Raafat, D., Holtfreter, S., Wietschel, K. A., van der Lans, S. P. A., Völker, U., Bröker, B. M., & Heck, A. J. R. (2025) · Science Advances · doi:10.1126/sciadv.adt7746 · Cited by 10
Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guérin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice
Arama, C., Assefaw‐Redda, Y., Rodrı́guez, A., Fernández, C., Corradin, G., Kaufmann, S. H. E., Reece, S. T., & Troye‐Blomberg, M. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.04.029 · Cited by 10
Relevance of antibody testing in patients with recurrent infections
Abraham, R. S. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.06.013 · Cited by 10
Antibody Boosting and Longevity Following Tetanus Immunization During Pregnancy
Fowkes, F. J. I., McGready, R. M., Johnstone-Robertson, S. P., Nosten, F. H., & Beeson, J. G. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis979 · Cited by 10
Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High T FH :T FR Ratios Drive Induction of Potent Neutralizing Antibody Responses
Eldi, P., Chaudhri, G., Nutt, S. L., Newsome, T. P., & Karupiah, G. (2019) · Journal of Virology · doi:10.1128/jvi.01795-18 · Cited by 10
Sequential Immunization With Heterologous Viruses Does Not Result in Attrition of the B Cell Memory in Rainbow Trout
Navelsaker, S., Magadán, S., Jouneau, L., Quillet, E., Olesen, N. J., Munang’andu, H. M., Boudinot, P., & Evensen, Ø. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02687 · Cited by 10
Long-term efficacy of nasal vaccination against enteric red mouth (ERM) disease and infectious hematopoietic necrosis (IHN) in juvenile rainbow trout (Oncorhynchus mykiss)
Ma, J., Casadei, E., Bruce, T. J., Sepahi, A., Cain, K. D., & Salinas, I. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.11.077 · Cited by 10
Effects of the age of vaccination on the humoral responses to a human papillomavirus vaccine
Nicoli, F., Mantelli, B., Gallerani, E., Telatin, V., Squarzon, L., Masiero, S., Gavioli, R., Palù, G., Barzon, L., & Caputo, A. (2022) · npj Vaccines · doi:10.1038/s41541-022-00458-0 · Cited by 10
Co-modulation of T cells and B cells enhances the inhibition of inflammation in experimental hypersensitivity pneumonitis
Courtemanche, O., Huppé, C.-A., Lecours, P. B., Lerdu, O., Roy, J., Lauzon‐Joset, J., Blanchet, M., Morissette, M. C., & Marsolais, D. (2022) · Respiratory Research · doi:10.1186/s12931-022-02200-9 · Cited by 10
B-cell immunity and vaccine induced antibody protection reveal the inefficacy of current vaccination schedule in infants with perinatal HIV-infection in Mozambique, Africa
Cotugno, N., Pallikkuth, S., Sanna, M., Dinh, V. B., de Armas, L. R., Rinaldi, S., Davis, S., Linardos, G., Pascucci, G. R., Pahwa, R., et al. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104666 · Cited by 10
State-of-the-Science of human papillomavirus vaccination in women with human immunodeficiency Virus: Summary of a scientific workshop
Schuind, A., Rees, H., Schiller, J. T., Mugo, N., Dull, P. M., Barnabas, R. V., Clifford, G. M., Liu, G., Madhi, S. A., Morse, R. B., et al. (2023) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2023.102331 · Cited by 10
Self-citation
serosim: An R package for simulating serological data arising from vaccination, epidemiological and antibody kinetics processes
Menezes, A., Takahashi, S., Routledge, I., Metcalf, C. J. E., Graham, A. L., & Hay, J. A. (2023) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1011384 · Cited by 10
Majority of human circulating IgG plasmablasts stop blasting in a cell-free pro-survival culture
Nguyen, D. C., Saney, C. L., Hentenaar, I., Cabrera-Mora, M., Capric, V., Woodruff, M. C., Andrews, J., Lonial, S., Sanz, I., & Lee, F. E.-H. (2024) · Scientific Reports · doi:10.1038/s41598-024-53977-2 · Cited by 10
Detection of Memory B Activity Against a Therapeutic Protein in Treatment-Naïve Subjects
Liao, K., Derbyshire, S., Wang, K.-F., Caucci, C., Tang, S., Holland, C., Loercher, A. E., & Gunn, G. R. (2018) · The AAPS Journal · doi:10.1208/s12248-018-0198-5 · Cited by 10
A cell-based in vitro assay for testing of immunological integrity of Tetanus toxoid vaccine antigen
Tichá, O., Klemm, D., Moos, L., & Bekeredjian‐Ding, I. (2021) · npj Vaccines · doi:10.1038/s41541-021-00344-1 · Cited by 10
Circulating IgA/IgG memory B cells against Mycobacterium tuberculosis dormancy-associated antigens Rv2659c and Rv3128c in active and latent tuberculosis
Soe, P. T., Hanthamrongwit, J., Saelee, C., Kyaw, S. P., Khaenam, P., Warit, S., Satproedprai, N., Mahasirimongkol, S., Yanai, H., Chootong, P., et al. (2021) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2021.07.033 · Cited by 11
The role of neutralizing antibodies by sVNT after two doses of BNT162b2 mRNA vaccine in a cohort of Italian healthcare workers
Infantino, M. G., Manfredi, M., Stacchini, L., Cosma, C., Grossi, V., Lari, B., Russo, E., Amedei, A., Benucci, M., Veneziani, F., et al. (2022) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2022-0170 · Cited by 10
Serological responses to human virome define clinical outcomes of Italian patients infected with SARS-CoV-2
Wang, L., Candia, J., Ma, L., Zhao, Y., Imberti, L., Sottini, A., Quirós-Roldán, E., Dobbs, K., Burbelo, P. D., Cohen, J. I., et al. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.78002 · Cited by 10
Host immune response to A(H1N1)pdm09 vaccination and infection: A one-year prospective study on six cohorts of subjects
Liu, W. Y., Ma, M., Tang, F., He, C., Zhang, X., Jiang, L.-F., Xin, D.-S., Hu, C., Looman, C. W. N., & Cao, W. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.05.030 · Cited by 10
Clinical images: The multifaceted pathogenesis of polymyalgia rheumatica/giant cell arteritis
Camellino, D., Sambuceti, G., Morbelli, S. D., & Cimmino, M. A. (2009) · Arthritis & Rheumatism · doi:10.1002/art.24770 · Cited by 10
Elevated antibody reactivity to measles virus NCORE protein among patients with multiple sclerosis and their healthy siblings with intrathecal oligoclonal immunoglobulin G production
Persson, L., Longhi, S., Enarsson, J., Andersen, O., Haghigi, S., Nilsson, S., Lagging, M., Johansson, M. E., & Bergström, T. B. (2014) · Journal of Clinical Virology · doi:10.1016/j.jcv.2014.06.011 · Cited by 10
Persistence and Half-lives of Anti-measles and Anti-rubella Antibodies in Japanese Hospital Workers: A Longitudinal Study
Kato, H., Mori, M., Oba, M. S., Kawahara, H., & Kaneko, T. (2016) · Internal Medicine · doi:10.2169/internalmedicine.55.6762 · Cited by 10
Vaccinations du voyageur adulte transplanté d’organes (à l’exclusion des receveurs de cellules souches hématopoïétiques)
Wyplosz, B., van der Vliet, D., Consigny, P., Calmus, Y., Mamzer, M., Guillemain, R., Malvy, D. J.-M., Samuel, D., Vittecoq, D., & Launay, O. (2008) · Médecine et Maladies Infectieuses · doi:10.1016/j.medmal.2008.11.006 · Cited by 10
MATHEMATICAL MODELS FOR VACCINATION, WANING IMMUNITY AND IMMUNE SYSTEM BOOSTING: A GENERAL FRAMEWORK
Barbarossa, M. V., & Röst, G. (2015) · International Symposium on Mathematical and Computational Biology (BIOMAT) · doi:10.1142/9789814667944_0012 · Cited by 10
TNF-α Limits Serological Memory by Disrupting the Bone Marrow Niche
Aaron, T., Laudermilch, E., Benet, Z. L., Ovando, L., Chandran, K., & Fooksman, D. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200053 · Cited by 9
Serum immunoglobulin and the threshold of Fc receptor-mediated immune activation
Bauer-Smith, H., Sudol, A. S. L., Beers, S. A., & Crispin, M. (2023) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2023.130448 · Cited by 10
Strengthening serological studies: the need for greater geographical diversity, biobanking, and data-accessibility
Menezes, A., Razafimahatratra, S. L., Wariri, O., Graham, A. L., & Metcalf, C. J. E. (2025) · Trends in Microbiology · doi:10.1016/j.tim.2024.12.006 · Cited by 10
The Importance of Monitoring Antigen-Specific Memory B Cells, and How ImmunoSpot Assays Are Suitable for This Task
Kirchenbaum, G. A., Pawelec, G., & Lehmann, P. (2025) · Cells · doi:10.3390/cells14030223 · Cited by 9
Influence of B cell-lineage targeted CAR-T cell therapy on humoral immunity and vaccine-induced antibody response
Ozog, S., Krantz, E. M., Tindbaek, K., Munoz, J., Liu, W. L., Chalal, C., Pernikoff, S., Yahya, K., Stevens‐Ayers, T., Dasgupta, S., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71473-1 · Cited by 9
Immunological memory to vaccines
Crotty, S. (2026) · Immunity · doi:10.1016/j.immuni.2026.02.019 · Cited by 9
Public health action following an outbreak of toxigenic cutaneous diphtheria in an Auckland refugee resettlement centre
Reynolds, G. E., Saunders, H., Matson, A., O'Kane, F., Roberts, S., Singh, S. K., VOSS, L. M., & Kiedrzynski, T. (2016) · Communicable Diseases Intelligence · doi:10.33321/cdi.2016.40.53 · Cited by 9
Cell-mediated immune responses to different formulations of a live-attenuated tetravalent dengue vaccine candidate in subjects living in dengue endemic and non-endemic regions
Moris, P., Bauer, K. M., Currier, J. R., Friberg, H., Eckels, K. H., Esquilin, I. O., Gibbons, R. V., Innis, B. L., Jarman, R. G., Simasathien, S., et al. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1581536 · Cited by 9
Directed attenuation to enhance vaccine immunity
Antia, R., Ahmed, H., & Bull, J. J. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1008602 · Cited by 9
Naturally Acquired Antibodies against Plasmodium falciparum: Friend or Foe?
Tijani, M. K., Lugaajju, A., & Persson, K. E. M. (2021) · Pathogens · doi:10.3390/pathogens10070832 · Cited by 9
Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial
Nouatin, O. P., Ibáñez, J., Fendel, R., Ngoa, U. A., Lorenz, F.-R., Agobe, J. C. D., Edoa, J. R., Flügge, J., Brückner, S., Esen, M., et al. (2022) · Malaria Journal · doi:10.1186/s12936-022-04169-8 · Cited by 9
Longitudinal IgG antibody responses to Plasmodium vivax blood-stage antigens during and after acute vivax malaria in individuals living in the Brazilian Amazon
Tashi, T., Upadhye, A., Kundu, P., Wu, C., Menant, S., Soares, R. R., Ferreira, M. U., Longley, R. J., Müeller, I., Hoang, Q. Q., et al. (2022) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0010773 · Cited by 9
A randomized, double-blind study on the safety and immunogenicity of rTSST-1 variant vaccine: phase 2 results
Schoergenhofer, C., Gelbenegger, G., Hasanacevic, D., Schöner, L., Steiner, M. M., Firbas, C., Buchtele, N., Derhaschnig, U., Tanzmann, A., Model, N., et al. (2024) · EClinicalMedicine · doi:10.1016/j.eclinm.2023.102404 · Cited by 9
HLA-DPB1 and anti-HBs titer kinetics in hepatitis B booster recipients who completed primary hepatitis B vaccination during infancy
T-W, W., Chu, C.-C., Liao, H.-W. C., Lin, S.-K., Ho, T., Lin, M., Lin, H., & Wang, L.-Y. (2013) · Genes and Immunity · doi:10.1038/gene.2013.62 · Cited by 9
Efficacy of recombinant measles virus expressing highly pathogenic avian influenza virus (HPAIV) antigen against HPAIV infection in monkeys
Fujiyuki, T., Horie, R., Yoneda, M., Kuraishi, T., Yasui, F., Kwon, H.-J., Munekata, K., Ikeda, F., Hoshi, M., Kiso, Y., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-08326-x · Cited by 9
Virus-Specific Secondary Plasma Cells Produce Elevated Levels of High-Avidity Antibodies but Are Functionally Short Lived
Krueger, C. C., Thoms, F., Keller, E., Vogel, M., & Bachmann, M. F. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01831 · Cited by 9
Safety of Multiple Vaccinations and Durability of Vaccine-Induced Antibodies in an Italian Military Cohort 5 Years after Immunization
Ferlito, C., Visco, V., Biselli, R., Cattaruzza, M. S., Carreras, G., Salerno, G., Lista, F. R., Capobianchi, M. R., Castilletti, C., Lapa, D., et al. (2021) · Biomedicines · doi:10.3390/biomedicines10010006 · Cited by 9
Extrapolating missing antibody-virus measurements across serological studies
Einav, T., & Cleary, B. (2022) · Cell Systems · doi:10.1016/j.cels.2022.06.001 · Cited by 9
Infection of Pro- and Anti-Inflammatory Macrophages by Wild Type and Vaccine Strains of Measles Virus: NLRP3 Inflammasome Activation Independent of Virus Production
Suwanmanee, S., Ghimire, S., Edwards, J. M., & Griffin, D. E. (2023) · Viruses · doi:10.3390/v15020260 · Cited by 9
Understanding B Cell Biology
Naradikian, M. S., Scholz, J. L., Oropallo, M. A., & Cancro, M. P. (2013) · Milestones in drug therapy · doi:10.1007/978-3-0348-0706-7_2 · Cited by 9
Comparison of the Immune Responses Induced by Chimeric Alphavirus-Vectored and Formalin-Inactivated Alum-Precipitated Measles Vaccines in Mice
Bergen, M. J., Pan, C.-H., Greer, C. E., Legg, H. S., Polo, J. M., & Griffin, D. E. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010297 · Cited by 9
Effects of highly active antiretroviral therapy on vaccine‐induced humoral immunity in HIV‐infected adults
González, R., Castro, P., García, F., Plana, M., Bayas, J. M., Lafuente, S., Serrano, B., Mora‐Peris, B., Argelich, R., Gatell, J., et al. (2010) · HIV Medicine · doi:10.1111/j.1468-1293.2010.00830.x · Cited by 9
Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients
Kobold, S., Luetkens, T., Bartels, B. M., Cao, Y., Hildebrandt, Y., Sezer, O., Reinhard, H., Templin, J., Bartels, K., Lajmi, N., et al. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/134081 · Cited by 9
Serological Protection Induced by Haemophilus influenzae Type b Conjugate Vaccine in Mexican Children: Is a Booster Dose of the Vaccine Needed?
Rodrı́guez, R. S., Mascareñas, C., Conde-Glez, C. J., Jaime Inostroza, S., Villanueva, S., Velázquez, M. E., Sánchez-Alemán, M. Á., & Echániz-Avilés, G. (2010) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00249-10 · Cited by 9
Negative IgG Varicella Zoster Virus Antibody Status: Immune Responses Pre and Post Re-immunization
Smith-Norowitz, T. A., Saadia, T. A., Norowitz, K. B., Joks, R. O., Durkin, H. G., & Kohlhoff, S. A. (2017) · Infectious Diseases and Therapy · doi:10.1007/s40121-017-0182-x · Cited by 9
Smallpox and vaccinia
Kennedy, R. B., Lane, J. M., Henderson, D. A., & Poland, G. A. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-0090-5.00010-0 · Cited by 9
Measles Virus (Rubeola)
Gershon, A. A. (2010) · Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases · doi:10.1016/b978-0-443-06839-3.00160-0 · Cited by 9
Acquired Immunity against Virus Infections
Szomolanyi‐Tsuda, E., Brehm, M. A., & Welsh, R. M. (2014) · ASM Press eBooks · doi:10.1128/9781555816872.ch19 · Cited by 9
The effects of preexisting immunity to influenza on responses to influenza vectors in mice
Langley, W. A., Bradley, K. C., Li, Z.-N., Talekar, G. R., Galloway, S. E., & Steinhauer, D. A. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.06.112 · Cited by 9
The strategy for prevention of measles and rubella prevalence with measles–rubella (MR) vaccine in Japan
Ihara, T. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.02.075 · Cited by 9
Passage-attenuated Powassan virus LI9P protects mice from lethal LI9 challenge and links envelope residue D308 to neurovirulence
Himmler, G. E., Mladinich, M. C., Conde, J. N., Gorbunova, E. E., Lindner, M. R., Kim, H. K., & Mackow, E. R. (2025) · mBio · doi:10.1128/mbio.00065-25 · Cited by 8
Engineering B cells to treat and study human disease
Trivedi, N. H., Pitner, R. A., Rawlings, D. J., & James, R. G. (2025) · Nature Biotechnology · doi:10.1038/s41587-025-02757-y · Cited by 8
A precision gene-engineered B cell medicine producing sustained levels of active factor IX for hemophilia B therapy
Liu, H., Singh, S., Mullen, T., Bullock, C., Keegan, S., Patterson, T., Thakur, S., Lundberg, A., Shenker, S., Couto, R., et al. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.09.001 · Cited by 8
Extrafollicular and Other Non‐Germinal Center B Cell Responses: An Evolutionary Perspective
Flowers, E. M., Siniscalco, E. R., & Eisenbarth, S. C. (2025) · Immunological Reviews · doi:10.1111/imr.70060 · Cited by 8
The multilayered identity of B cell memory
Glaros, V., Francis, N., & Kreslavsky, T. (2026) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01377-5 · Cited by 9
Fasting impairs humoral immunological memory by β-hydroxybutyrate-mediated depletion of plasma cells
Zhu, Y., Ding, B., Lv, H., Xu, H., Chen, J., Xu, J., Wu, Q., Hao, X., Hu, Y., Guo, J., et al. (2026) · Immunity · doi:10.1016/j.immuni.2026.01.002 · Cited by 9
Antigen avidity potentiates the durability of the vaccine immune response
Weidner, N. G., Padilla, M. V., Pruitt, L., Cottrell, C. A., Gonzales, K. A., Kalyuzhniy, O., Lu, D., Alavi, N. B., Phelps, N., Aniqua, M., et al. (2026) · Science Translational Medicine · doi:10.1126/scitranslmed.aee5273 · Cited by 8

Authors: Amanna, I. J., Carlson, N. E., & Slifka, M. K.
Affiliations: Oregon Health & Science University (US)
ORCID: Amanna, Ian J.
Carlson, Nichole E.
Slifka, Mark K.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2007-11-08
Volume: 357
Issue: 19
Pages: 1903-1915
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmoa066092
OpenAlex: W2128666074
Cited by: 1,286
References: 38
Citations by year: 2026: 60 · 2025: 81 · 2024: 82 · 2023: 72 · 2022: 103 · 2021: 127 · 2020: 73 · 2019: 60 · 2018: 64 · 2017: 64 · 2016: 52 · 2015: 47 · 2014: 68 · 2013: 67 · 2012: 66
FWCI: 17.94
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (P01AG023664)
National Center for Research Resources (RR000163, P51RR000163, M01RR000334, UL1RR024140, RR024140, RR 000334)
Topics: Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
Keywords: humoral immunity, antibody half-life, memory B cells, long-term antibody persistence, vaccine antigens, measles, mumps, rubella, varicella-zoster virus, Epstein-Barr virus, tetanus toxoid, diphtheria toxoid, protective immunity
MeSH terms: Adult, Aging, Antibodies, Bacterial, Antibodies, Viral, Antibody Formation, Antigens, Bacterial, Antigens, Viral, B-Lymphocytes, Diphtheria, Female, Half-Life, Humans, Longitudinal Studies, Male, Middle Aged, Plasma Cells, Tetanus, Time Factors, Vaccines, Virus Diseases, Seroepidemiologic Studies, Lymphocyte Count

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Duration of Humoral Immunity to Common Viral and Vaccine Antigens

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks