Skin cancers after organ transplantation
Abstract
Skin cancers are the most common tumors in patients who have received organ transplants. This review discusses the epidemiology, pathogenesis, and management of squamous-cell and basal-cell carcinomas, cancers of the anogenital region, Kaposi's sarcoma, melanoma, neuroendocrine skin carcinoma, and cutaneous manifestations of lymphoma in transplant recipients.
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Patients in chronic immunosuppression status are prone to develop skin cancers, primarily in areas exposed to the sun.
“It is well known that patients in chronic immunosuppression status (such as patients with organ transplants receiving intense immunosuppressive therapy to prevent rejection) are prone to develop skin cancers, primarily in areas exposed to the sun [123].”
From Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy (2013) · cites this paper as [123]
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- Authors
- Euvrard, S., Kanitakis, J., & Claudy, A.
- Affiliations
- Hôpital Edouard Herriot (FR)
- ORCID
- Kanitakis, Jean
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2003-04-24
- Volume
- 348
- Issue
- 17
- Pages
- 1681-1691
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2133408276
- Cited by
- 1,575
- References
- 0
- Citations by year
- 2026: 45 · 2025: 30 · 2024: 42 · 2023: 46 · 2022: 59 · 2021: 65 · 2020: 79 · 2019: 71 · 2018: 90 · 2017: 94 · 2016: 82 · 2015: 80 · 2014: 84 · 2013: 64 · 2012: 67
- FWCI
- 8.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Nonmelanoma Skin Cancer Studies
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
- Keywords
- skin cancer, organ transplantation, squamous cell carcinoma, basal cell carcinoma, anogenital cancer, Kaposi's sarcoma, melanoma, neuroendocrine skin carcinoma, cutaneous lymphoma, immunosuppression, pathogenesis
- MeSH terms
- Basal Cell Carcinoma, Carcinoma, Squamous Cell, Female, Humans, Immunosuppression Therapy, Male, Melanoma, Risk Factors, Sarcoma, Kaposi, Skin Neoplasms, Urogenital Neoplasms, Organ Transplantation
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