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Treating Disease at the RNA Level with Oligonucleotides
Abstract
Interview with Dr. Arthur A. Levin on the use of oligonucleotide drugs that regulate RNA. (10:24)Download As research on the structure and function of RNAs has rapidly expanded, so too has the number of oligonucleotide drugs in clinical development that regulate RNA. This article describes several examples and suggests where the field is headed.
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Some ASOs are clinically approved for certain neuromuscular diseases and are currently in trials for other conditions.
“Some ASOs were clinically approved for certain neuromuscular diseases and are currently in trials for other conditions.184,185”
From MiR-128-3p – a gray eminence of the human central nervous system (2024) · cites this paper as [185]
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MiR-128-3p – a gray eminence of the human central nervous system
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Metadata
- Authors
- Levin, A. A.
- Affiliations
- From Research and Development, Avidity Biosciences, La Jolla, CA.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2019-01-03
- Volume
- 380
- Issue
- 1
- Pages
- 57-70
- ISSN
- 0028-4793
- 1533-4406
- Cited by
- 287
- References
- 15
- Language
- en
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