The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
A trap-and-release integrated microfluidic system for dynamic microarray applications
Open accessAbstract
Dynamic microarrays hold great promise for advancing research in proteomics, diagnostics and drug discovery. However, this potential has yet to be fully realized due to the lack of reliable multifunctional platforms to transport and immobilize particles, infuse reagents, observe the reaction, and retrieve selected particles. We achieved all these functions in a single integrated device through the combination of hydrodynamic and optical approaches. Hydrodynamic forces allow simultaneous transportation and immobilization of large number of particles, whereas optical-based microbubble technique for bead retrieval gives dexterity in handling individual particles without complicated circuitry. Based on the criterion derived in this paper, the device was designed, and fabricated using standard photolithography and soft lithography methods. We examined the dynamics of bubble formation and dissipation in the device, and parametric studies revealed that higher power settings at short intervals were more efficient than low power settings at longer intervals for bead retrieval. We also demonstrated the capabilities of our device and its potential as a tool for screening methods such as the “one-bead-one-compound” (OBOC) combinatorial library method. Although both approaches, hydrodynamic confinement and optical-based microbubbles, are presented in one device, they can also be separately used for other applications in microchip devices.
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Light-Directed, Spatially Addressable Parallel Chemical Synthesis
Fodor, S. P. A., Read, J. L., Pirrung, M. C., Stryer, L., Lu, A. T., & Solas, D. (1991) · Science · doi:10.1126/science.1990438 · Cited by 2,696
A new type of synthetic peptide library for identifying ligand-binding activity
Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierski, W. M., & Knapp, R. J. (1991) · Nature · doi:10.1038/354082a0 · Cited by 1,802
Generation of Solution and Surface Gradients Using Microfluidic Systems
Jeon, N. L., Dertinger, S. K. W., Chiu, D. T., Choi, I. S., Stroock, A. D., & Whitesides, G. M. (2000) · Langmuir · doi:10.1021/la000600b · Cited by 963
Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array
Singh-Gasson, S., Green, R. D., Yue, Y., Nelson, C., Blattner, F., Sussman, M. R., & Cerrina, F. (1999) · Nature Biotechnology · doi:10.1038/13664 · Cited by 733
Autoantigen microarrays for multiplex characterization of autoantibody responses
Robinson, W. H., DiGennaro, C., Hueber, W., Haab, B. B., Kamachi, M., Dean, E. J., Fournel, S., Fong, D., Genovese, M. C., De Vegvar, H. E. N., et al. (2002) · Nature Medicine · doi:10.1038/nm0302-295 · Cited by 673
Microfluidic Device for Single-Cell Analysis
Wheeler, A. R., Throndset, W. R., Whelan, R. J., Leach, A. M., Zare, R. N., Liao, Y. H., Farrell, K., Manger, I. D., & Daridon, A. (2003) · Analytical Chemistry · doi:10.1021/ac0340758 · Cited by 600
Large-Scale Single-Cell Trapping And Imaging Using Microwell Arrays
Rettig, J. R., & Folch, A. (2005) · Analytical Chemistry · doi:10.1021/ac0505977 · Cited by 502
Di Carlo, D., Aghdam, N., & Lee, L. P. (2006) · Analytical Chemistry · doi:10.1021/ac060541s · Cited by 458
Decoding Randomly Ordered DNA Arrays
Gunderson, K. L., Kruglyak, S., Graige, M. S., Garcia, F., Kermani, B. G., Zhao, C., Che, D., Dickinson, T., Wickham, E., Bierle, J., et al. (2004) · Genome Research · doi:10.1101/gr.2255804 · Cited by 326
Single-Cell Microarray for Analyzing Cellular Response
Yamamura, S., Kishi, H., Tokimitsu, Y., Kondo, S., Honda, R., Rao, S. R., Omori, M., Tamiya, E., & Muraguchi, A. (2005) · Analytical Chemistry · doi:10.1021/ac0515632 · Cited by 258
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Monodisperse Alginate Hydrogel Microbeads for Cell Encapsulation
Tan, W. ‐., & Takeuchi, S. (2007) · Advanced Materials · doi:10.1002/adma.200700433 · Cited by 599
Self-citationA microfluidic platform integrating functional vascularized organoids-on-chip
Quintard, C., Tubbs, E., Jonsson, G., Jiao, J., Wang, J., Werschler, N., Laporte, C., Pitaval, A., Bah, T.-S., Pomeranz, G., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45710-4 · Cited by 387
Automated cellular sample preparation using a Centrifuge-on-a-Chip
Mach, A. J., Kim, J. H., Arshi, A., Hur, S. C., & Di Carlo, D. (2011) · Lab on a Chip · doi:10.1039/c1lc20330d · Cited by 280
Silicon-based microfilters for whole blood cell separation
Ji, H. M., Samper, V., Chen, Y., Heng, C. K., Lim, T. M., & Yobas, L. (2008) · Biomedical Microdevices · doi:10.1007/s10544-007-9131-x · Cited by 272
Metadata
- Authors
- Tan, W.-H., & Takeuchi, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2007-01-23
- Volume
- 104
- Issue
- 4
- Pages
- 1146-1151
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1970292634
- Cited by
- 591
- References
- 15
- FWCI
- 17.37
- Type
- journal article
- Language
- en
- Open access
- green
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