The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
The frailty of adaptive hypotheses for the origins of organismal complexity
Open accessAbstract
The vast majority of biologists engaged in evolutionary studies interpret virtually every aspect of biodiversity in adaptive terms. This narrow view of evolution has become untenable in light of recent observations from genomic sequencing and population-genetic theory. Numerous aspects of genomic architecture, gene structure, and developmental pathways are difficult to explain without invoking the nonadaptive forces of genetic drift and mutation. In addition, emergent biological features such as complexity, modularity, and evolvability, all of which are current targets of considerable speculation, may be nothing more than indirect by-products of processes operating at lower levels of organization. These issues are examined in the context of the view that the origins of many aspects of biological diversity, from gene-structural embellishments to novelties at the phenotypic level, have roots in nonadaptive processes, with the population-genetic environment imposing strong directionality on the paths that are open to evolutionary exploitation.
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Cites
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Self-citationGene Regulatory Networks and the Evolution of Animal Body Plans
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Turning a hobby into a job: How duplicated genes find new functions
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Experimental evolution of multicellularity
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The bioenergetic costs of a gene
Lynch, M., & Marinov, G. K. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1514974112 · Cited by 600
Self-citationThe evolution of cell types in animals: emerging principles from molecular studies
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The outer subventricular zone and primate-specific cortical complexification
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Metadata
- Authors
- Lynch, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2007-05-15
- Volume
- 104
- Issue
- suppl_1
- Pages
- 8597-8604
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2171501215
- Cited by
- 817
- References
- 10
- FWCI
- 26.46
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
