Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior

Astrocytes give rise to new neurons in the adult mammalian hippocampus

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Adult hippocampal neurogenesis in depression

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Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus

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Role of neurotrophic factors in depression

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Inducible gene deletion in astroglia and radial glia—A valuable tool for functional and lineage analysis

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Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

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Neurotrophin regulation of neural circuit development and function

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Reduced anxiety-like behavior and central neurochemical change in germ-free mice: Behavior in germ-free mice

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BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity

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Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer

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The microbiome-gut-brain axis: from bowel to behavior

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The GABAergic deficit hypothesis of major depressive disorder

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The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity

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Exercise-Mediated Neurogenesis in the Hippocampus via BDNF

Liu, P. Z., & Nusslock, R. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00052 · Cited by 533 · see citing works

The neurobiology of depression and antidepressant action

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Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

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Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis

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The Role of BDNF on Neural Plasticity in Depression

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Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

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All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis

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Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

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Neurobiology of local and intercellular BDNF signaling

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Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress

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Chronic peripheral inflammation, hippocampal neurogenesis, and behavior

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Adult neurogenesis: integrating theories and separating functions

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Targeting TRK family proteins in cancer

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BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission

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Neuronal plasticity and antidepressant actions

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BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

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Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles

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Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

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Interface between hypothalamic‐pituitary‐adrenal axis and brain‐derived neurotrophic factor in depression

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BDNF Val66Met impairs fluoxetine-induced enhancement of adult hippocampus plasticity

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The Role of Dietary Polyphenols on Adult Hippocampal Neurogenesis: Molecular Mechanisms and Behavioural Effects on Depression and Anxiety

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A comprehensive review of genetic and epigenetic mechanisms that regulate <i>BDNF</i> expression and function with relevance to major depressive disorder

Hing, B., Sathyaputri, L., & Potash, J. B. (2018) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32616 · Cited by 137 · see citing works

BDNF in the dentate gyrus is required for consolidation of “pattern-separated” memories.

Bekinschtein, P., Kent, B. A., Oomen, C. A., Clemenson, G. D., Gage, F. H., Saksida, L. M., & Bussey, T. J. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.09.027 · Cited by 124 · see citing works

Ablating adult neurogenesis in the rat has no effect on spatial processing: evidence from a novel pharmacogenetic model

Groves, J. O., Leslie, I., Huang, G.-J., McHugh, S. B., Taylor, A., Mott, R., Munafò, M., Bannerman, D. M., & Flint, J. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003718 · Cited by 121 · see citing works

Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

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Deletion of Running-Induced Hippocampal Neurogenesis by Irradiation Prevents Development of an Anxious Phenotype in Mice

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Multiplex quantitative assays indicate a need for reevaluating reported small-molecule TrkB agonists

Boltaev, U., Meyer, Y., Tolibzoda, F., Jacques, T., Gassaway, M., Xu, Q., Wagner, F., Zhang, Y.-L., Palmer, M., Holson, E., et al. (2017) · Science Signaling · doi:10.1126/scisignal.aal1670 · Cited by 94 · see citing works

Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories.

Bekinschtein, P., Kent, B. A., Oomen, C. A., Clemenson, G. D., Gage, F. H., Saksida, L. M., & Bussey, T. J. (2014) · Hippocampus · doi:10.1002/hipo.22304 · Cited by 94 · see citing works

Phenotypical and functional heterogeneity of neural stem cells in the aged hippocampus

Martín‐Suárez, S., Valero, J., Muro‐García, T., & Encinas, J. M. (2019) · Aging Cell · doi:10.1111/acel.12958 · Cited by 58 · see citing works

BDNF and CREB1 genetic variants interact to affect antidepressant treatment outcomes in geriatric depression

Murphy, G. M., Sarginson, J. E., Ryan, H. S., O’Hara, R., Schatzberg, A. F., & Lazzeroni, L. C. (2013) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e328360b175 · Cited by 50 · see citing works

Methylphenidate Decreases ATP Levels and Impairs Glutamate Uptake and Na+,K+-ATPase Activity in Juvenile Rat Hippocampus

Schmitz, F., Pierozan, P., Rodrigues, A. F., Biasibetti, H., Grings, M., Zanotto, B., Coelho, D. M., Vargas, C. R., Leipnitz, G., & Wyse, A. T. S. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-0289-1 · Cited by 35 · see citing works

Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene

Gupta, R., Dittmeier, M., Wohlleben, G., Nickl, V., Bischler, T., Luzak, V., Wegat, V., Doll, D., Sodmann, A., Bady, E., et al. (2024) · Cancer Gene Therapy · doi:10.1038/s41417-024-00809-0 · Cited by 7 · see citing works