The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Restoration of function after brain damage using a neural prosthesis
Open accessAbstract
Significance: Closed-loop systems, or brain–machine–brain interfaces (BMBIs), have not been widely developed for brain repair. In this study, we targeted spared motor and somatosensory regions of the rat brain after traumatic brain injury for establishment of a functional bridge using a battery-powered microdevice. The results show that by using discriminated action potentials as a trigger for stimulating a distant cortical location, rapid recovery of fine motor skills is facilitated. This study provides strong evidence that BMBIs can be used to bridge damaged neural pathways functionally and promote recovery after brain injury. Although this study is restricted to a rodent model of TBI, it is likely that the approach will also be applicable to other types of acquired brain injuries.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“This cooperation probably plays an essential role in the reorganization of neuronal pathways that mediate neurological recovery in response to neurorehabilitation with the BSI.”
From Walking naturally after spinal cord injury using a brain–spine interface (2023) · cites this paper as [40]
Citations
Cites
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,424
indicated, N. A. (1950) · Journal of Consulting Psychology · doi:10.1037/h0049612 · Cited by 6,984
Malenka, R. C., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.012 · Cited by 3,968
Generalized, Linear, and Mixed Models
McCulloch, C. E., & Searle, S. R. (2000) · Wiley series in probability and statistics · doi:10.1002/0471722073 · Cited by 3,057
The Spike-Timing Dependence of Plasticity
Feldman, D. E. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.001 · Cited by 1,071
Functional Reorganization of the Rat Motor Cortex Following Motor Skill Learning
Kleim, J. A., Barbay, S., & Nudo, R. J. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.6.3321 · Cited by 806
Self-citationSynaptic mechanisms for plasticity in neocortex
Feldman, D. E. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135516 · Cited by 704
Extensive Cortical Rewiring after Brain Injury
Dancause, N., Barbay, S., Frost, S. B., Plautz, E. J., Chen, D., Zoubina, E. V., Stowe, A. M., & Nudo, R. J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3256-05.2005 · Cited by 704
Self-citationMotor areas in the frontal lobe of the primate
DUM, R., & STRICK, P. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(02)00929-0 · Cited by 653
D.O. Hebb: The Organization of Behavior, Wiley: New York; 1949
Morris, R. (1999) · Brain Research Bulletin · doi:10.1016/s0361-9230(99)00182-3 · Cited by 561
Research works printed but not linked: 2
- 10.1113/jphysiol.1973.sp010273 · DOI · Paper page
- Committee for the Update of the Guide for the Care and Use of Laboratory Animals (2011) Guide for the Care and Use of Laboratory Animals (The National Academies Press Washington DC).
Cited by
Sorted by citations
Embedded Devices for Neuromorphic Time-Series Assessment
Mazumder, A. N., Hosseini, M., & Mohsenin, T. (2022) · Research Explorer (The University of Manchester) · doi:10.13016/m2ksy0-wxr3 · Cited by 662
Brain-Machine Interfaces: From Basic Science to Neuroprostheses and Neurorehabilitation
Lebedev, M., & Nicolelis, M. A. L. (2017) · Physiological Reviews · doi:10.1152/physrev.00027.2016 · Cited by 695
Brain-actuated functional electrical stimulation elicits lasting arm motor recovery after stroke
Biasiucci, A., Leeb, R., Iturrate, I., Perdikis, S., Al-Khodairy, A., Corbet, T., Schnider, A., Schmidlin, T., Zhang, H., Bassolino, M., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04673-z · Cited by 649
Walking naturally after spinal cord injury using a brain–spine interface
Lorach, H., Galvez, A., Spagnolo, V., Martel, F., Karakas, S., Intering, N., Vat, M., Faivre, O., Harte, C., Komi, S., et al. (2023) · Nature · doi:10.1038/s41586-023-06094-5 · Cited by 631
Brain–machine interfaces in neurorehabilitation of stroke
Soekadar, S. R., Birbaumer, N., Slutzky, M. W., & Cohen, L. G. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.11.025 · Cited by 352
Metadata
- Authors
- Guggenmos, D. J., Azin, M., Barbay, S., Mahnken, J. D., Dunham, C., Mohseni, P., & Nudo, R. J.
- Affiliations
- University of Kansas Medical Center (US)
- Case Western Reserve University (US)
- Biostatistics, and
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2013-12-09
- Volume
- 110
- Issue
- 52
- Pages
- 21177-21182
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC3876197
- OpenAlex
- W2147851954
- Cited by
- 221
- References
- 50
- Citations by year
- 2026: 14 · 2025: 13 · 2024: 8 · 2023: 15 · 2022: 21 · 2021: 19 · 2020: 17 · 2019: 16 · 2018: 27 · 2017: 19 · 2016: 16 · 2015: 21 · 2014: 14
- FWCI
- 8.34
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- other-oa
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Keywords
- neural prosthesis, neural interfaces, brain injury recovery, focal brain lesions, premotor cortex, somatosensory cortex, microelectrodes, reach-to-grasp, functional connectivity, rat model
- MeSH terms
- Action Potentials, Animals, Brain Injuries, Male, Motor Cortex, Motor Skills, Neural Pathways, Linear Models, Rats, Long-Evans, Rats, Neural Prostheses, Brain-Computer Interfaces
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
