Cited by 146Bartonella species infections researchZoonotic diseases and public healthYersinia bacterium, plague, ectoparasites research

Declines in large wildlife increase landscape-level prevalence of rodent-borne disease in Africa

Open access
Young, Hillary S., Dirzo, Rodolfo, Helgen, Kristofer M., McCauley, Douglas J., Billeter, Sarah A., Kosoy, Michael Y., Osikowicz, Lynn M., Salkeld, Daniel J. +2 more·2014·Proceedings of the National Academy of Sciences

Abstract

Significance: Understanding the effects of biodiversity loss on zoonotic disease is of pressing importance to both conservation science and public health. This paper provides experimental evidence of increased landscape-level disease risk following declines in large wildlife, using the case study of the rodent-borne zoonosis, bartonellosis, in East Africa. This pattern is driven not by changes in community composition or diversity of hosts, as frequently proposed in other systems, but by increases in abundance of susceptible hosts following large mammal declines. Given that rodent increases following large wildlife declines appear to be a widespread pattern, we suggest this relationship is likely to be general.

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Crossref · 10.1073/pnas.1404958111

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  • Ecological extinctions are well known in terrestrial environments and have been demonstrated to be just as disruptive as species extinctions.

    “Ecological extinctions are well known in terrestrial environments and have been demonstrated to be just as disruptive as species extinctions (20).”

    From Marine defaunation: Animal loss in the global ocean (2015) · cites this paper as [20]

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Authors
Young, H. S., Dirzo, R., Helgen, K. M., McCauley, D. J., Billeter, S. A., Kosoy, M. Y., Osikowicz, L. M., Salkeld, D. J., Young, T. P., & Dittmar, K.
Affiliations
  • Smithsonian Institution (US)
  • Department of Biology and
  • University of California, Santa Barbara (US)
  • Centers for Disease Control and Prevention (US)
  • Colorado State University (US)
  • University of California, Davis (US)
  • University at Buffalo, State University of New York (US)
Venue
Proceedings of the National Academy of Sciences
Published
2014-04-28
Volume
111
Issue
19
Pages
7036-7041
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2154261096
Cited by
146
References
69
Citations by year
2026: 5 · 2025: 15 · 2024: 10 · 2023: 12 · 2022: 20 · 2021: 10 · 2020: 11 · 2019: 4 · 2018: 10 · 2017: 15 · 2016: 15 · 2015: 14 · 2014: 5
FWCI
11.89
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion, other-oa)
Funders
  • National Science Foundation (97-07477, 0316402, 0816453)
  • Smithsonian Institution
  • National Geographic Society
  • U.S. Fish and Wildlife Service (98210‐0‐G563)
  • Division of Environmental Biology (09-09670)
Topics
  • Life Sciences › Immunology and Microbiology › Parasitology › Bartonella species infections research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Zoonotic diseases and public health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Yersinia bacterium, plague, ectoparasites research
Keywords
defaunation, rodent-borne zoonoses, Bartonella, bartonellosis, rodent density, savanna ecosystems, host regulation, disease transmission risk, East Africa
MeSH terms
Africa, Eastern, Animals, Animals, Wild, Bartonella Infections, Humans, Kenya, Lice Infestations, Risk Factors, Rodent Diseases, Rodentia, Zoonoses, Prevalence, Ecosystem, Biodiversity, Xenopsylla, Flea Infestations

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