Cited by 420SARS-CoV-2 and COVID-19 ResearchZoonotic diseases and public healthAnimal Virus Infections Studies

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

SARS-like WIV1-CoV poised for human emergence

Open access

Menachery, Vineet D., Yount, Boyd L., Sims, Amy C., Debbink, Kari, Agnihothram, Sudhakar S., Gralinski, Lisa E., Graham, Rachel L., Scobey, Trevor, Plante, Jessica A., Royal, Scott R., Swanstrom, Jesica, Sheahan, Timothy P., Pickles, Raymond J., Corti, Davide, Randell, Scott H., Lanzavecchia, Antonio, Marasco, Wayne A., Baric, Ralph S.·2016·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.1517719113PMC PMC4801244

Open this paper in CoChat — free account Open PDF

Abstract

Significance: The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV highlights the continued risk of cross-species transmission leading to epidemic disease. This manuscript describes efforts to extend surveillance beyond sequence analysis, constructing chimeric and full-length zoonotic coronaviruses to evaluate emergence potential. Focusing on SARS-like virus sequences isolated from Chinese horseshoe bats, the results indicate a significant threat posed by WIV1-CoV. Both full-length and chimeric WIV1-CoV readily replicated efficiently in human airway cultures and in vivo, suggesting capability of direct transmission to humans. In addition, while monoclonal antibody treatments prove effective, the SARS-based vaccine approach failed to confer protection. Together, the study indicates an ongoing threat posed by WIV1-related viruses and the need for continued study and surveillance.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1073/pnas.1517719113

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Ge, X.-Y., Li, J.-L., Yang, X.-L., Chmura, A. A., Zhu, G., Epstein, J. H., Mazet, J. K., Hu, B., Zhang, W., Peng, C., et al. (2013) · Nature · doi:10.1038/nature12711 · Cited by 1,778
Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2
Netland, J., Meyerholz, D. K., Moore, S., Cassell, M., & Perlman, S. (2008) · Journal of Virology · doi:10.1128/jvi.00737-08 · Cited by 1,293
Severe acute respiratory syndrome
Peiris, M. J. S., Guan, Y., & Yuen, K. (2004) · Nature Medicine · doi:10.1038/nm1143 · Cited by 1,157
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
Qiu, X., Wong, G., Audet, J., Bello, A., Fernando, L., Alimonti, J. B., Fausther‐Bovendo, H., Wei, H., Aviles, J., Hiatt, E., et al. (2014) · Nature · doi:10.1038/nature13777 · Cited by 984
Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission
Graham, R. L., & Baric, R. S. (2009) · Journal of Virology · doi:10.1128/jvi.01394-09 · Cited by 753
Self-citation
An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus
Traggiai, E., Becker, S., Subbarao, K., Kolesnikova, L., Uematsu, Y., Gismondo, M. R., Murphy, B. R., Rappuoli, R., & Lanzavecchia, A. (2004) · Nature Medicine · doi:10.1038/nm1080 · Cited by 697
Self-citation
A decade after SARS: strategies for controlling emerging coronaviruses
Graham, R. L., Donaldson, E., & Baric, R. S. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3143 · Cited by 689
Self-citation
A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge
Bolles, M., Deming, D., Long, K., Agnihothram, S., Whitmore, A., Ferris, M., Funkhouser, W., Gralinski, L., Totura, A., Heise, M., et al. (2011) · Journal of Virology · doi:10.1128/jvi.06048-11 · Cited by 477
Self-citation
A Mouse-Adapted SARS-Coronavirus Causes Disease and Mortality in BALB/c Mice
Roberts, A., Deming, D., Paddock, C. D., Cheng, A., Yount, B. L., Vogel, L., Herman, B. D., Sheahan, T., Heise, M. T., Genrich, G. L., et al. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030005 · Cited by 447
Self-citation
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus
Yount, B., Curtis, K. M., Fritz, E. A., Hensley, L. E., Jahrling, P., Prentice, E., Denison, M., Geisbert, T., & Baric, R. (2003) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1735582100 · Cited by 394
Self-citation

Show all 27 references

Sorted by citations

Items 101–200 of 420

COVID-19 preclinical models: human angiotensin-converting enzyme 2 transgenic mice
Lutz, C. M., Maher, L. A., Lee, C., & Kang, W. (2020) · Human Genomics · doi:10.1186/s40246-020-00272-6 · Cited by 95
Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines
Prakash, S., Srivastava, R., Coulon, P.-G. A., Dhanushkodi, N. R., Chentoufi, A. A., Tifrea, D. F., Edwards, R. A., Figueroa, C. J., Schubl, S. D., Hsieh, L. L., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2001438 · Cited by 91
Origin, Potential Therapeutic Targets and Treatment for Coronavirus Disease (COVID-19)
Nadeem, M. S., Zamzami, M. A., Choudhry, H., Murtaza, B. N., Kazmi, I. A., Ahmad, H., & Shakoori, A. R. (2020) · Pathogens · doi:10.3390/pathogens9040307 · Cited by 95
Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein
Tortorici, M. A., Walls, A. C., Joshi, A., Park, Y., Eguia, R. T., Miranda, M. C., Kepl, E., Dosey, A. M., Stevens‐Ayers, T., Boeckh, M. J., et al. (2022) · Cell · doi:10.1016/j.cell.2022.05.019 · Cited by 89
Self-citation
Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses
Nathan, A., Rossin, E. J., Kaseke, C., Park, R. J.-H., Khatri, A., Koundakjian, D., Urbach, J. M., Singh, N. K., Bashirova, A. A., Tano-Menka, R., et al. (2021) · Cell · doi:10.1016/j.cell.2021.06.029 · Cited by 84
A strategy to assess spillover risk of bat SARS-related coronaviruses in Southeast Asia
Sánchez, C. A., Li, H., Phelps, K. L., Zambrana‐Torrelio, C., Wang, L., Zhou, P., Shi, Z., Olival, K. J., & Daszak, P. (2022) · Nature Communications · doi:10.1038/s41467-022-31860-w · Cited by 98
How host genetics dictates successful viral zoonosis
Warren, C. J., & Sawyer, S. L. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000217 · Cited by 90
Biodiversity loss and COVID-19 pandemic: The role of bats in the origin and the spreading of the disease
Platto, S., Zhou, J., Wang, Y., Wang, H., & Carafoli, E. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.10.028 · Cited by 91
In Vitro and In Vivo Models for Studying SARS-CoV-2, the Etiological Agent Responsible for COVID-19 Pandemic
Rosa, R. B., Dantas, W. M., do Nascimento, J. C. F., da Silva, M. V., de Oliveira, R. N., & Pena, L. (2021) · Viruses · doi:10.3390/v13030379 · Cited by 89
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection
Li, W., Chen, C., Drelich, A. K., Martinez, D. R., Gralinski, L. E., Sun, Z., Schäfer, A., Kulkarni, S. S., Liu, X., Leist, S. R., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2010197117 · Cited by 82
Self-citation
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge
Muruato, A. E., Vu, M. N., Johnson, B. A., Davis-Gardner, M. E., Vanderheiden, A., Lokugamage, K. G., Schindewolf, C., Crocquet-Valdes, P. A., Langsjoen, R. M., Plante, J. A., et al. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001284 · Cited by 77
Self-citation
A Review on COVID-19: Origin, Spread, Symptoms, Treatment, and Prevention
(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac106.72347242 · Cited by 81
Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice
Gralinski, L. E., Menachery, V. D., Morgan, A. P., Totura, A. L., Beall, A. E., Kocher, J., Plante, J. A., Harrison-Shostak, D. C., Schäfer, A., de Villena, F. P., et al. (2017) · G3 Genes Genomes Genetics · doi:10.1534/g3.117.041434 · Cited by 79
Self-citation
Infectious Disease Threats: A Rebound To Resilience
Daszak, P., Keusch, G. T., Phelan, A., Johnson, C. K., & Osterholm, M. T. (2021) · Health Affairs · doi:10.1377/hlthaff.2020.01544 · Cited by 78
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
Pinto, D., Park, Y., Beltramello, M., Walls, A. C., Tortorici, M. A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., Marco, A. D., et al. (2020) · Worldwide Protein Data Bank · doi:10.2210/pdb6ws6/pdb · Cited by 82
Self-citation
Interplay between co-divergence and cross-species transmission in the evolutionary history of bat coronaviruses
Leopardi, S., Holmes, E. C., Gastaldelli, M., Tassoni, L., Priori, P., Scaravelli, D., Zamperin, G., & Benedictis, P. D. (2018) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2018.01.012 · Cited by 74
Identification of a novel lineage bat SARS-related coronaviruses that use bat ACE2 receptor
Guo, H., Hu, B., Si, H.-R., Zhu, Y., Zhang, W., Li, B., Li, A., Geng, R., Lin, H.-F., Yang, X.-L., et al. (2021) · Emerging Microbes & Infections · doi:10.1080/22221751.2021.1956373 · Cited by 71
“Moreover, the ACE2 usage viruses in bat SARSr-CoV-1 lineage appear to be more dangerous in cross-species transmission, as demonstrated in animal studies [23,24].”
Background
COVID-19 and future pandemics: a global systems approach and relevance to SDGs
Thoradeniya, T., & Jayasinghe, S. (2021) · Globalization and Health · doi:10.1186/s12992-021-00711-6 · Cited by 71
Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions
Shiakolas, A. R., Kramer, K. J., Wrapp, D., Richardson, S. I., Schäfer, A., Wall, S. C., Wang, N., Janowska, K., Pilewski, K. A., Venkat, R., et al. (2021) · Cell Reports Medicine · doi:10.1016/j.xcrm.2021.100313 · Cited by 75
Self-citation
Virome analysis for identification of novel mammalian viruses in bats from Southeast China
Hu, D., Zhu, C., Wang, Y., Ai, L., Yang, L., Ye, F., Ding, C., Chen, J., He, B., Zhu, J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-11384-w · Cited by 70
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1 Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response
Zeng, L., Gao, Y.-T., Ge, X., Zhang, Q., Peng, C., Yang, X., Tan, B., Chen, J., Chmura, A. A., Daszak, P., et al. (2016) · Journal of Virology · doi:10.1128/jvi.03079-15 · Cited by 69
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines
Menachery, V. D., Gralinski, L. E., Mitchell, H. D., Dinnon, K. H., Leist, S. R., Yount, B. L., McAnarney, E. T., Graham, R. L., Waters, K. M., & Baric, R. S. (2018) · Journal of Virology · doi:10.1128/jvi.00710-18 · Cited by 67
Self-citation
An overview on Coronaviruses family from past to Covid-19: introduce some inhibitors as antiviruses from Gillan’s plants
(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac103.575585 · Cited by 73
SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways
Verma, A. K., Zheng, J. H., Meyerholz, D. K., & Perlman, S. M. (2022) · JCI Insight · doi:10.1172/jci.insight.160277 · Cited by 76
ACE2 mouse models: a toolbox for cardiovascular and pulmonary research
Jia, H., Yue, X., & Lazartigues, E. D. (2020) · Nature Communications · doi:10.1038/s41467-020-18880-0 · Cited by 63
Lung repair and regeneration: Advanced models and insights into human disease
Basil, M. C., Alysandratos, K., Kotton, D. N., & Morrisey, E. E. (2024) · Cell stem cell · doi:10.1016/j.stem.2024.02.009 · Cited by 65
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
He, W., Musharrafieh, R. G., Song, G., Dueker, K., Tse, L. V., Martinez, D. R., Schäfer, A., Callaghan, S., Yong, P., Beutler, N., et al. (2022) · Nature Immunology · doi:10.1038/s41590-022-01222-1 · Cited by 58
Self-citation
The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primatesPreprint
Li, D.-P., Edwards, R., Manne, K., Martinez, D. R., Schäfer, A., Alam, S., Wiehe, K., Lu, X.-Z., Parks, R., Sutherland, L. L., et al. (2021) · bioRxiv · doi:10.1101/2020.12.31.424729 · Cited by 62
Self-citation
A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site
Onodera, T., Kita, S., Adachi, Y., Moriyama, S., Sato, A., Nomura, T., Sakakibara, S., Inoue, T., Tadokoro, T., Anraku, Y., et al. (2021) · Immunity · doi:10.1016/j.immuni.2021.08.025 · Cited by 61
SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism
Jing, Y., Luo, L., Chen, Y., Westerberg, L. S., Zhou, P., Xu, Z. P., Herrada, A. A., Park, C.-S., Kubo, M., Mei, H., et al. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00749-3 · Cited by 61
SARS‐CoV‐2, Covid‐19, and the debunking of conspiracy theories
Hakim, M. S. (2021) · Reviews in Medical Virology · doi:10.1002/rmv.2222 · Cited by 64
Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19
Varona, J. F., Landete, P., Lopez-Martin, J. A., Estrada, V., Paredes, R., Guisado‐Vasco, P., de Orueta, L. F., Torralba, M., Fortün, J., Vates, R., et al. (2022) · Life Science Alliance · doi:10.26508/lsa.202101200 · Cited by 59
Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
Fan, C., Cohen, A. A., Park, M., Hung, A. F.-H., Keeffe, J. R., Gnanapragasam, P. N. P., Lee, Y. E., Gao, H., Kakutani, L. M., Wu, Z., et al. (2022) · Immunity · doi:10.1016/j.immuni.2022.10.019 · Cited by 56
Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform
Graham, R. L., Deming, D., Deming, M. E., Yount, B. L., & Baric, R. S. (2018) · Communications Biology · doi:10.1038/s42003-018-0175-7 · Cited by 58
Self-citation
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses
Feldman, J. E., Bals, J., Altomare, C. G., Denis, K. S., Lam, E. C., Hauser, B. M., Ronsard, L., Sangesland, M., Moreno, T. B., Okonkwo, V., et al. (2021) · Science Immunology · doi:10.1126/sciimmunol.abl5842 · Cited by 60
Multivalent S2-based vaccines provide broad protection against SARS-CoV-2 variants of concern and pangolin coronaviruses
Halfmann, P., Frey, S. J., Loeffler, K., Kuroda, M., Maemura, T., Armbrust, T., Yang, J. E., Hou, Y. J., Baric, R. S., Wright, E., et al. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104341 · Cited by 54
Self-citation
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine
Feng, Y., Yuan, M., Powers, J. M., Hu, M., Munt, J. E., Arunachalam, P. S., Leist, S. R., Bellusci, L., Kim, J., Sprouse, K. R., et al. (2023) · Science Translational Medicine · doi:10.1126/scitranslmed.adg7404 · Cited by 58
Self-citation
Bat SARS-Like WIV1 coronavirus uses the ACE2 of multiple animal species as receptor and evades IFITM3 restriction via TMPRSS2 activation of membrane fusion
Zheng, M., Zhao, X., Zheng, S., Chen, D., Du, P., Li, X., Jiang, D., Guo, J., Zeng, H., & Lin, H. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1787797 · Cited by 58
Understanding bat SARS-like coronaviruses for the preparation of future coronavirus outbreaks—implications for coronavirus vaccine development
Ng, O.-W., & Tan, Y.-J. (2017) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2016.1228500 · Cited by 51
A palindromic RNA sequence as a common breakpoint contributor to copy-choice recombination in SARS-COV-2
Gallaher, W. R. (2020) · Archives of Virology · doi:10.1007/s00705-020-04750-z · Cited by 58
Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells
Holwerda, M., Kelly, J. N., Laloli, L., Stürmer, I., Portmann, J., Stalder, H., & Dijkman, R. (2019) · Viruses · doi:10.3390/v11040377 · Cited by 49
Novel insights into the treatment of SARS-CoV-2 infection: An overview of current clinical trials
Oroojalian, F., Haghbin, A., Baradaran, B., Hemmat, N., Shahbazi, M., Baghi, H. B., Mokhtarzadeh, A., & Hamblin, M. R. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.09.204 · Cited by 51
COVID‐19: A systematic review and update on prevention, diagnosis, and treatment
Aliabadi, H. A. M., Eivazzadeh‐Keihan, R., Parikhani, A. B., Mehraban, S. F., Maleki, A. R., Fereshteh, S., Bazaz, M., Zolriasatein, A., Bozorgnia, B., Rahmati, S., et al. (2022) · MedComm · doi:10.1002/mco2.115 · Cited by 50
Mouse genome rewriting and tailoring of three important disease loci
Zhang, W., Golynker, I., Brosh, R., Fajardo, Á., Zhu, Y., Wudzinska, A. M., Ordóñez, R., Ribeiro-dos-Santos, A. M., Carrau, L., Damani‐Yokota, P., et al. (2023) · Nature · doi:10.1038/s41586-023-06675-4 · Cited by 52
Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals
Cohen, A. A., Keeffe, J. R., Schiepers, A., Dross, S., Greaney, A. J., Rorick, A. V., Gao, H., Gnanapragasam, P. N. P., Fan, C., West, A. P., et al. (2024) · Cell · doi:10.1016/j.cell.2024.07.052 · Cited by 51
Effective drugs used to combat SARS-CoV-2 infection and the current status of vaccines
Awadasseid, A., Wu, Y., Tanaka, Y., & Zhang, W. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111330 · Cited by 50
SARS Coronavirus Redux
Qing, E., & Gallagher, T. (2020) · Trends in Immunology · doi:10.1016/j.it.2020.02.007 · Cited by 48
ACTIVating Resources for the COVID-19 Pandemic: In Vivo Models for Vaccines and Therapeutics
Hewitt, J., Lutz, C. M., Florence, W. C., Pitt, M. L. M., Rao, S., Rappaport, J., & Haigwood, N. L. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.09.016 · Cited by 47
Betacoronavirus Genomes: How Genomic Information has been Used to Deal with Past Outbreaks and the COVID-19 Pandemic
Llanes, A., Restrepo, C. M., Zuleima Caballero, E., Rajeev, S., Kennedy, M. A., & Lleonart, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21124546 · Cited by 52
Intranasal gene therapy to prevent infection by SARS-CoV-2 variants
Sims, J. J., Greig, J. A., Michalson, K. T., Lian, S., Martino, R. A., Meggersee, R., Turner, K. B., Nambiar, K., Dyer, C., Hinderer, C. J., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009544 · Cited by 42
Broad-Spectrum Coronavirus Fusion Inhibitors to Combat COVID-19 and Other Emerging Coronavirus Diseases
Wang, X., Xia, S., Wang, Q., Xu, W., Li, W., Lu, L., & Jiang, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21113843 · Cited by 46
Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination
Adams, L. E., Leist, S. R., Dinnon, K. H., West, A., Gully, K. L., Anderson, E. J., Loome, J. F., Madden, E. A., Powers, J. M., Schäfer, A., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112326 · Cited by 46
Self-citation
Permissivity of Dipeptidyl Peptidase 4 Orthologs to Middle East Respiratory Syndrome Coronavirus Is Governed by Glycosylation and Other Complex Determinants
Peck, K. M., Scobey, T., Swanstrom, J., Jensen, K., Burch, C. L., Baric, R. S., & Heise, M. T. (2017) · Journal of Virology · doi:10.1128/jvi.00534-17 · Cited by 44
Self-citation
Novel Alphacoronaviruses and Paramyxoviruses Cocirculate with Type 1 and Severe Acute Respiratory System (SARS)-Related Betacoronaviruses in Synanthropic Bats of Luxembourg
Pauly, M., Pir, J. B., Loesch, C., Sausy, A., Snoeck, C. J., Hübschen, J. M., & Muller, C. P. (2017) · Applied and Environmental Microbiology · doi:10.1128/aem.01326-17 · Cited by 44
Immunoinformatics and Molecular Docking Studies Predicted Potential Multiepitope‐Based Peptide Vaccine and Novel Compounds against Novel SARS‐CoV‐2 through Virtual Screening
Waqas, M., Haider, A., Rehman, A., Qasim, M., Umar, A., Sufyan, M., Akram, H. N., Mir, A. M., Razzaq, R., Rasool, D., et al. (2021) · BioMed Research International · doi:10.1155/2021/1596834 · Cited by 42
Human coronavirus spike protein-host receptor recognition
Guruprasad, L. (2020) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2020.10.006 · Cited by 47
The chronicles of coronaviruses: the bronchitis, the hepatitis and the common cold
Lalchhandama, K. (2020) · Science Vision · doi:10.33493/scivis.20.01.04 · Cited by 42
The Neighborhood of the Spike Gene Is a Hotspot for Modular Intertypic Homologous and Nonhomologous Recombination in Coronavirus Genomes
Nikolaidis, M., Markoulatos, P., de Peer, Y. V., Oliver, S. G., & Amoutzias, G. D. (2021) · Molecular Biology and Evolution · doi:10.1093/molbev/msab292 · Cited by 42
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection
Wei, J., Patil, A., Collings, C. K., Alfajaro, M. M., Liang, Y., Cai, W. L., Strine, M. S., Filler, R. B., DeWeirdt, P. C., Hanna, R. E., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01307-z · Cited by 41
A Precision Medicine Approach to SARS-CoV-2 Pandemic Management
Crisci, C. D., Ardusso, L., Mossuz, A., & Müller, L. (2020) · Current Treatment Options in Allergy · doi:10.1007/s40521-020-00258-8 · Cited by 41
The green tea catechin EGCG provides proof-of-concept for a pan-coronavirus attachment inhibitor
LeBlanc, E. V., & Colpitts, C. C. (2022) · Scientific Reports · doi:10.1038/s41598-022-17088-0 · Cited by 39
Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity
Chen, W., Hajduczki, A., Martinez, E. J., Bai, H., Matz, H. C., Hill, T. M., Lewitus, É., Chang, W. C., Dawit, L., Peterson, C. E., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36106-x · Cited by 39
Genetically modified mouse models to help fight COVID-19
Gurumurthy, C. B., Quadros, R. M., Richardson, G. P., Poluektova, L. Y., Mansour, S. L., & Ohtsuka, M. (2020) · Nature Protocols · doi:10.1038/s41596-020-00403-2 · Cited by 39
SARS-CoV-2 immunity in animal models
Chen, Z., Yuan, Y., Hu, Q., Zhu, A., Chen, F., Li, S., Guan, X., Lv, C., Tang, T., He, Y., et al. (2024) · Cellular and Molecular Immunology · doi:10.1038/s41423-023-01122-w · Cited by 39
A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in micePreprint
Martinez, D. R., Schaefer, A., Gobeil, S., Li, D., la Cruz, G. D., Parks, R., Lu, X., Barr, M., Manne, K., Mansouri, K., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.27.441655 · Cited by 37
Self-citation
ACE2-Independent Bat Sarbecovirus Entry and Replication in Human and Bat Cells
Guo, H., Li, A., Dong, T.-Y., Su, J., Yao, Y., Zhu, Y., Shi, Z., & Letko, M. C. (2022) · mBio · doi:10.1128/mbio.02566-22 · Cited by 36
Development of a Broadly Accessible Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Platform
Agnihothram, S., Menachery, V. D., Yount, B. L., Lindesmith, L. C., Scobey, T., Whitmore, A. C., Schäfer, A., Heise, M. T., & Baric, R. S. (2018) · Journal of Virology · doi:10.1128/jvi.00027-18 · Cited by 36
Self-citation
Host range, transmissibility and antigenicity of a pangolin coronavirus
Hou, Y. J., Chiba, S., Leist, S. R., Meganck, R. M., Martinez, D. R., Schäfer, A., Catanzaro, N., Sontake, V., West, A., Edwards, C. E., et al. (2023) · Nature Microbiology · doi:10.1038/s41564-023-01476-x · Cited by 36
Self-citation
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus
Lee, J., Zepeda, S. K., Park, Y., Taylor, A. L., Quispe, J. D., Stewart, C., Leaf, E. M., Treichel, C., Corti, D., King, N. P., et al. (2023) · Cell Host & Microbe · doi:10.1016/j.chom.2023.10.018 · Cited by 33
Self-citation
Discovery and genetic analysis of novel coronaviruses in least horseshoe bats in southwestern China
Wang, L., Fu, S., Cao, Y., Zhang, H., Feng, Y., Yang, W., Nie, K., Ma, X., & Liang, G. (2017) · Emerging Microbes & Infections · doi:10.1038/emi.2016.140 · Cited by 34
Evolutionary relationships and sequence‐structure determinants in human SARS coronavirus‐2 spike proteins for host receptor recognition
Guruprasad, L. (2020) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.25967 · Cited by 34
Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles
Kocher, J., Lindesmith, L. C., Debbink, K. M., Beall, A. E., Mallory, M. L., Yount, B. L., Graham, R. L., Huynh, J., Gates, J. E., Donaldson, E., et al. (2018) · mBio · doi:10.1128/mbio.00869-18 · Cited by 34
Self-citation
Prevention and Control Strategies for SARS-CoV-2 Infection
Srivastava, N., & Saxena, S. K. (2020) · Medical virology · doi:10.1007/978-981-15-4814-7_11 · Cited by 33
Brain cross‐protection against SARS‐CoV‐2 variants by a lentiviral vaccine in new transgenic mice
Ku, M., Authié, P., Bourgine, M., Anna, F., Noirat, A., Moncoq, F., Vesin, B., Névo, F., Lopez, J., Souque, P., et al. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202114459 · Cited by 30
Animal models for SARS‐CoV‐2 infection and pathology
Bi, Z., Hong, W., Yang, H. J., Lu, S., & Peng, X. (2021) · MedComm · doi:10.1002/mco2.98 · Cited by 35
Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine
Halfmann, P., Loeffler, K., Duffy, A., Kuroda, M., Yang, J. E., Wright, E., Kawaoka, Y., & Kane, R. S. (2024) · Nature Communications · doi:10.1038/s41467-024-45495-6 · Cited by 31
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats
Wang, N., Luo, C., Liu, H.-Z., Yang, X.-L., Hu, B., Zhang, W., Li, B., Zhu, Y., Zhu, G.-J., Shen, X.-R., et al. (2019) · Viruses · doi:10.3390/v11040379 · Cited by 36
Infectivity, virulence, pathogenicity, host-pathogen interactions of SARS and SARS-CoV-2 in experimental animals: a systematic review
Sarkar, J., & Guha, R. (2020) · Veterinary Research Communications · doi:10.1007/s11259-020-09778-9 · Cited by 32
A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex
Yazdi, A. K., Li, F., Devkota, K., Perveen, S., Ghiabi, P., Hajian, T., Bolotokova, A., & Vedadi, M. (2021) · SLAS DISCOVERY · doi:10.1177/24725552211008863 · Cited by 32
Therapeutic potential of melatonin and melatonergic drugs on K18‐hACE2 mice infected with SARS‐CoV‐2
Cecon, E., Izabelle, C., Poder, S. L., Real, F., Zhu, A., Tu, L., Ghigna, M., Klonjkowski, B., Bomsel, M., Jockers, R., et al. (2021) · Journal of Pineal Research · doi:10.1111/jpi.12772 · Cited by 33
Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques following SARS-CoV-2 Vaccination and Infection
Jacob-Dolan, C., Feldman, J. E., McMahan, K., Yu, J., Zahn, R. C., Wegmann, F., Schuitemaker, H., Schmidt, A. G., & Barouch, D. H. (2021) · Journal of Virology · doi:10.1128/jvi.00117-21 · Cited by 32
Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting
Hauser, B. M., Sangesland, M., Denis, K. S., Lam, E. C., Case, J. B., Windsor, I. W., Feldman, J. E., Caradonna, T. M., Kannegieter, T., Diamond, M., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110561 · Cited by 38
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirusPreprint
Sheahan, T. P., Sims, A. M., Zhou, S., Graham, R. L., Hill, C. S., Leist, S. R., Schäfer, A., Dinnon, K. H., Montgomery, S. A., Agostini, M. L., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.19.997890 · Cited by 31
Self-citation
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Song, G., Yuan, M., Liu, H., Capozzola, T., Lin, R. N., Torres, J. L., He, W., Musharrafieh, R., Dueker, K., Zhou, P.-P., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115948 · Cited by 30
Mouse Models for the Study of SARS-CoV-2 Infection
Knight, A. C., Montgomery, S. A., Fletcher, C., & Baxter, V. K. (2021) · Comparative Medicine · doi:10.30802/aalas-cm-21-000031 · Cited by 31
Interspecies Jumping of Bat Coronaviruses
Wong, A. C. P., Lau, S. K. P., & Woo, P. C. Y. (2021) · Viruses · doi:10.3390/v13112188 · Cited by 30
Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primatesPreprint
Erasmus, J. H., Khandhar, A. P., Walls, A. C., Hemann, E. A., O’Connor, M. A., Murapa, P., Archer, J. F., Leventhal, S. S., Fuller, J., Lewis, T. B., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.28.121640 · Cited by 30
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice
Cohen, A. A., Gnanapragasam, P. N. P., Lee, Y. E., Hoffman, P. R., Ou, S. K.-H., Kakutani, L. M., Keeffe, J. R., Wu, H., Howarth, M. R., West, A. P., et al. (2021) · CaltechAUTHORS (California Institute of Technology) · Cited by 29
SARS-CoV-2, Early Entry Events
CHAMBERS, J. K., Yu, J., Valdés, J. J., & Arulanandam, B. P. (2020) · Journal of Pathogens · doi:10.1155/2020/9238696 · Cited by 32
The emerging SARS-CoV, MERS-CoV, and SARS-CoV-2: An insight into the viruses zoonotic aspects
Al-Salihi, K. A., & Khalaf, J. M. (2021) · Veterinary World · doi:10.14202/vetworld.2021.190-199 · Cited by 29
Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions
Renn, M., Bartok, E., Zillinger, T., Hartmann, G., & Behrendt, R. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.107931 · Cited by 28
Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine
Coléon, S., Wiedemann, A., Surénaud, M., Lacabaratz, C., Hüe, S., Prague, M., Cervantes-Gonzalez, M., Wang, Z., Ellis, J., Sansoni, A., et al. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104062 · Cited by 29
The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2
Allen, J. D., Ivory, D. P., Song, G., He, W., Capozzola, T., Yong, P., Burton, D. R., Andrabi, R., & Crispin, M. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112307 · Cited by 32
Organoids in virology
Chu, J. T. S., & Lamers, M. M. (2024) · npj Viruses · doi:10.1038/s44298-024-00017-5 · Cited by 31
Evaluation of Coronavirus Families & Covid-19 Proteins: Molecular Modeling Study
(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac105.60396057 · Cited by 28
Evolution, Ecology, and Zoonotic Transmission of Betacoronaviruses: A Review
Jelinek, H. F., Mousa, M., Alefishat, E. A., Osman, W. M., Spence, I., Bu, D., Feng, S. F., Byrd, J. H., Magni, P. A., Sahibzada, S., et al. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.644414 · Cited by 28
Deciphering the biology of porcine epidemic diarrhea virus in the era of reverse genetics
Teeravechyan, S., Frantz, P. N., Wongthida, P., Chailangkarn, T., Jaru-Ampornpan, P., Koonpaew, S., & Jongkaewwattana, A. (2016) · Virus Research · doi:10.1016/j.virusres.2016.05.003 · Cited by 27
Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses
Cockrell, A. S., Beall, A. E., Yount, B. L., & Baric, R. S. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6964-7_5 · Cited by 27
Self-citation
Glycan engineering of the SARS-CoV-2 receptor-binding domain elicits cross-neutralizing antibodies for SARS-related viruses
Shinnakasu, R., Sakakibara, S., Yamamoto, H. H., Wang, P.-H., Moriyama, S., Sax, N., Ono, C., Yamanaka, A., Adachi, Y., Onodera, T., et al. (2021) · The Journal of Experimental Medicine · doi:10.1084/jem.20211003 · Cited by 28
Host Kinase CSNK2 is a Target for Inhibition of Pathogenic SARS-like β-Coronaviruses
Yang, X., Dickmander, R. J., Bayati, A., Taft-Benz, S., Smith, J. L., Wells, C. I., Madden, E. A., Brown, J. W., Lenarcic, E. M., Yount, B. L., et al. (2022) · ACS Chemical Biology · doi:10.1021/acschembio.2c00378 · Cited by 29
Self-citation

Authors: Menachery, V. D., Yount, B. L., Sims, A. C., Debbink, K., Agnihothram, S. S., Gralinski, L. E., Graham, R. L., Scobey, T., Plante, J. A., Royal, S. R., Swanstrom, J., Sheahan, T. P., Pickles, R. J., Corti, D., Randell, S. H., Lanzavecchia, A., Marasco, W. A., & Baric, R. S.
Affiliations: University of North Carolina at Chapel Hill (US)
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
National Center for Toxicological Research (US)
ETH Zurich (CH)
Harvard University (US)
ORCID: Menachery, Vineet D.
Yount, Boyd L.
Debbink, Kari
Gralinski, Lisa E.
Graham, Rachel L.
Scobey, Trevor
Plante, Jessica A.
Royal, Scott R.
Swanstrom, Jesica
Sheahan, Timothy P.
Pickles, Raymond J.
Corti, Davide
Randell, Scott H.
Lanzavecchia, Antonio
Marasco, Wayne A.
Baric, Ralph S.
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 2016-03-14
Volume: 113
Issue: 11
Pages: 3048-3053
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.1517719113
PMC: PMC4801244
OpenAlex: W2298153446
Cited by: 418
References: 27
Citations by year: 2026: 14 · 2025: 24 · 2024: 37 · 2023: 36 · 2022: 44 · 2021: 84 · 2020: 117 · 2019: 17 · 2018: 16 · 2017: 19 · 2016: 10
FWCI: 19.09
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.pnas.org/preview_site/misc/userlicense.xhtml (vor)
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: HHS | NIH | National Institute of Allergy and Infectious Diseases (U19AI109761, U19AI107810, F32AI102561)
Division of Intramural Research, National Institute of Allergy and Infectious Diseases (AI1085524)
HHS | NIH | National Institute on Aging (K99AG049092)
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (DK065988)
Topics: Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Zoonotic diseases and public health
Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
Keywords: SARS-like coronaviruses, zoonotic viruses, viral emergence, metagenomics, reverse genetics, pathogenicity, reservoir hosts, human-to-human transmission
MeSH terms: Angiotensin-Converting Enzyme 2, Animals, Antibodies, Monoclonal, Antibodies, Viral, Cells, Cultured, Chlorocebus aethiops, Chiroptera, Coronaviridae, Coronaviridae Infections, Cross Reactions, Epithelial Cells, Humans, Peptidyl-Dipeptidase A, Lung, Mice, Inbred BALB C, Mice, Transgenic, Models, Molecular, Protein Conformation, Receptors, Virus, Recombinant Fusion Proteins, Species Specificity, Vero Cells, Virus Replication, Zoonoses, Point Mutation, Encephalitis, Viral, Communicable Diseases, Emerging, Severe acute respiratory syndrome-related coronavirus, Mice, Antibodies, Neutralizing, Host Specificity, Spike Glycoprotein, Coronavirus

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

SARS-like WIV1-CoV poised for human emergence

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks