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Preschool is a sensitive period for the influence of maternal support on the trajectory of hippocampal development
Abstract
Significance: Data from a longitudinal neuroimaging study beginning in the preschool period and including three brain scans through school age and early adolescence were used to investigate the effects of maternal support on the development of the hippocampus. Consistent with animal findings showing that early support enhances hippocampal development and later adaptive coping, findings demonstrated that early childhood maternal support predicted a steeper hippocampal growth trajectory. The data also suggested that early childhood was a sensitive period when the effects of support had a more powerful effect on hippocampal growth. The hippocampal growth trajectory was associated with better emotion regulation in early adolescence. Findings suggest that enhancing early childhood maternal support fosters healthy childhood brain development and emotion functioning.
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From Prenatal Social Determinants of Health: Narrative review of maternal environments and neonatal brain development (2024) · cites this paper as [7]
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BackgroundThe neurobiological consequences of early stress and childhood maltreatment
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Cited by
Early environmental influences on the development of children's brain structure and function
Miguel, P. M., Pereira, L. O., Silveira, P. P., & Meaney, M. J. (2019) · Developmental Medicine & Child Neurology · doi:10.1111/dmcn.14182 · Cited by 358
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“…many of the current studies on the relationship between early environmental factors and brain outcomes are not able to rule out either GE correlations or third variables that are correlated with both the environment and brain factors (Hanson et al., 2011; Luby et al., 2016; Noble et al., 2015).”
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Metadata
- Authors
- Luby, J. L., Belden, A., Harms, M. P., Tillman, R., & Barch, D. M.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2016-04-25
- Volume
- 113
- Issue
- 20
- Pages
- 5742-5747
- ISSN
- 0027-8424
- 1091-6490
- Cited by
- 142
- References
- 15
- Language
- en
- Funders
- HHS | NIH | National Institute of Mental Health (PA-07-070 NIMH R01, R01 MH064769-)
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