PPARα is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Minokoshi, Y., Kim, Y.-B., Peroni, O. D., Fryer, L. G. D., Müller, C., Carling, D., & Kahn, B. B. (2002) · Nature · doi:10.1038/415339a · Cited by 2,053

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

Yoon, J. C., Puigserver, P., Chen, G., Donovan, J., Wu, Z., Rhee, J., Adelmant, G., Stafford, J., Kahn, C. R., Granner, D. K., et al. (2001) · Nature · doi:10.1038/35093050 · Cited by 1,821

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

Abu-Elheiga, L., Matzuk, M. M., Abo-Hashema, K. A. H., & Wakil, S. J. (2001) · Science · doi:10.1126/science.1056843 · Cited by 903

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

Shimomura, I., Bashmakov, Y. K., Ikemoto, S., Horton, J. D., Brown, M. S., & Goldstein, J. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.24.13656 · Cited by 779

A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis.

McGarry, J. D., Mannaerts, G. P., & Foster, D. W. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108764 · Cited by 736

Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Shimabukuro, M., Koyama, K., Chen, G., Wang, M.-Y., Trieu, F., Lee, Y., Newgard, C. B., & Unger, R. H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4637 · Cited by 646

ADD1: a Novel Helix-Loop-Helix Transcription Factor Associated with Adipocyte Determination and Differentiation

Tontonoz, P., Kim, J. B., Graves, R. A., & Spiegelman, B. M. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.8.4753-4759.1993 · Cited by 599

Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase

Woods, A., Azzout‐Marniche, D., Foretz, M., STEIN, S. C., Lemarchand, P., Ferré, P., Foufelle, F., & Carling, D. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6704-6711.2000 · Cited by 417

Association study between gene polymorphisms in PPAR signaling pathway and porcine meat quality traits

He, K., Wang, Q., Wang, Z., & Pan, Y. (2013) · Mammalian Genome · doi:10.1007/s00335-013-9460-4 · Cited by 37

Effects of β‐aminoisobutyric acid on leptin production and lipid homeostasis: mechanisms and possible relevance for the prevention of obesity

Begriche, K., Massart, J., & Fromenty, B. (2009) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2009.00765.x · Cited by 36

DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the ω-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways

SanGiovanni, J. P., Chen, J., Sapieha, P. S., Aderman, C. M., Stahl, A., Clemons, T. E., Chew, E. Y., & Smith, L. E. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053155 · Cited by 34

Physiological and pathophysiological regulation of regional adipose tissue in the development of insulin resistance and type 2 diabetes

Rattarasarn, C. (2006) · Acta Physiologica · doi:10.1111/j.1748-1716.2005.01521.x · Cited by 34

The Potential Role of PPARs in the Fetal Origins of Adult Disease

Guo, J., Wu, J., He, Q., Zhang, M., Li, H., & Liu, Y. (2022) · Cells · doi:10.3390/cells11213474 · Cited by 30

PPARs: Interference with Warburg’ Effect and Clinical Anticancer Trials

Vamecq, J., Colet, J., Eynde, J. J. V., Briand, G., Porchet, N., & Rocchi, S. (2012) · PPAR Research · doi:10.1155/2012/304760 · Cited by 28

Hepatic Gene Expression Profile of Lipid Metabolism in Rats: Impact of Caloric Restriction and Growth Hormone/Insulin-Like Growth Factor-1 Suppression

Higami, Y., Tsuchiya, T., Chiba, T., Yamaza, H., Muraoka, I., Hirose, M., Komatsu, T., & Shimokawa, I. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.11.1099 · Cited by 28

Obesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivo

Powell, D. R. (2006) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00220.x · Cited by 28

Adiponectin and leptin: Potential tools in the differential diagnosis of pediatric diabetes?

Huerta, M. G. (2006) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-006-9017-x · Cited by 26

Leptin induces hypertrophy through activating the peroxisome proliferator‐activated receptor α pathway in cultured neonatal rat cardiomyocytes

Hou, N., Luo, M., Liu, S., Zhang, H., Xiao, Q., Sun, P., Zhang, G., Luo, J., & Chen, M. (2010) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2010.05442.x · Cited by 25

Trajectory of leptin and leptin receptor in vertebrates: Structure, function and their regulation

Bakshi, A., Singh, R. K., & Rai, U. (2021) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2021.110652 · Cited by 28

Identification and Saturable Nature of Signaling Pathways Induced by Metreleptin in Humans: Comparative Evaluation of In Vivo, Ex Vivo, and In Vitro Administration

Moon, H., Huh, J. Y., Dincer, F., Schneider, B. E., Hasselgren, P., & Mantzoros, C. S. (2014) · Diabetes · doi:10.2337/db14-0625 · Cited by 24

Unripe Rubus coreanus Miquel Extract Containing Ellagic Acid Promotes Lipolysis and Thermogenesis In Vitro and In Vivo

Kim, K. J., Jeong, E.-S., Lee, K. H., Na, J.-R., Park, S., Kim, J. S., Na, C.-S., Kim, Y. R., & Kim, S. (2020) · Molecules · doi:10.3390/molecules25245954 · Cited by 23

RESISTANCE TO EXCESSIVE BODYWEIGHT GAIN IN RISPERIDONE‐INJECTED RATS

Ota, M., Mori, K., Nakashima, A., Kaneko, Y. S., Takahashi, H., & Ota, A. (2005) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2005.04184.x · Cited by 23

Niacin: Vitamin and Antidyslipidemic Drug

Jacobson, E. L., Kim, H., Kim, M., & Jacobson, M. K. (2011) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-2199-9_3 · Cited by 21

A comprehensive review on clinically proven medicinal plants in the treatment of overweight and obesity, with mechanistic insights

Aziz, M. A., Millat, M. S., Akter, T., Hossain, M. S., Islam, M. M., Mohsin, S., Ansari, F., Kabir, A., Amin, M. N., & Islam, M. S. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13493 · Cited by 20

Aged interleukin-10tm1Cgn chronically inflamed mice have substantially reduced fat mass, metabolic rate, and adipokines

Westbrook, R., Yang, H., Langdon, J., Roy, C. N., Kim, J. A., Choudhury, P. P., Xue, Q., Francesco, A. D., de Cabo, R., & Walston, J. D. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186811 · Cited by 20

The offspring from rats fed a fatty diet display impairments in the activation of liver peroxisome proliferator activated receptor alpha and features of fatty liver disease

Heinecke, F., Mazzucco, M. B., Fornes, D. D., Roberti, S. L., Jawerbaum, A., & White, V. (2020) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2020.110818 · Cited by 19

The regulation of acyl-CoA dehydrogenases in adipose tissue by rosiglitazone.

Goetzman, E. S. (2009) · Obesity · doi:10.1038/oby.2008.467 · Cited by 17

Association between leptin and NAFLD: a two-sample Mendelian randomization study

Guo, Z., Chen, H., Zao, X., Hongbo, D. U., Guo, Y., Jin, Q., Kong, D., Li, X., Zhang, T., Yun, Z., et al. (2023) · European journal of medical research · doi:10.1186/s40001-023-01147-x · Cited by 19

Environment-physiology, diet quality and energy balance: The influence of early life nutrition on future energy balance

Burdge, G. C., & Lillycrop, K. A. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.12.007 · Cited by 17

The herbal composition GGEx18 fromLaminaria japonica, Rheum palmatum, andEphedra sinicareduces obesity via skeletal muscle AMPK and PPARα

Shin, S. S., Park, D., Lee, H. Y., Hong, Y., Choi, J., Oh, J.-H., Lee, H., Lee, H. R., Kim, M.-R., Shen, Z. B., et al. (2011) · Pharmaceutical Biology · doi:10.3109/13880209.2011.618502 · Cited by 18

Protein kinase C‐mediated phosphorylation of orphan nuclear receptor TR2: Effects on receptor stability and activity

Khan, S. A., Park, S. W., Huq, M. D. M., & Wei, L. (2005) · PROTEOMICS · doi:10.1002/pmic.200402062 · Cited by 17

Ligand‐independent orphan receptor TR2 activation by phosphorylation at the DNA‐binding domain

Khan, S. A., Park, S. W., Huq, M. D. M., & Wei, L. (2005) · PROTEOMICS · doi:10.1002/pmic.200500068 · Cited by 17

Leptin resistance during pregnancy is also exerted at the periphery†

Trujillo‐Güiza, M. L., & Señarís, R. M. (2018) · Biology of Reproduction · doi:10.1093/biolre/ioy024 · Cited by 16

Deficiency of PPARα disturbs the response of lipogenic flux and of lipogenic and cholesterogenic gene expression to dietary cholesterol in mouse white adipose tissue

Islam, K., Knight, B. L., Frayn, K. N., Patel, D., & Gibbons, G. F. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2005.03.009 · Cited by 16

The Role of Leptin Levels in Adaptation to Cold Climates

Никанорова, А. А., Алексеевич, Б. Н., Сергеевич, Н. С., Пшенникова, В. Г., Solovyev, A. V., Romanov, G. P., Семеновна, К. С., Sazonov, N. N., Бурцева, Т. Е., Odland, J. Ø., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17061854 · Cited by 14

Maternal saturated-fat-rich diet promotes leptin resistance in fetal liver lipid catabolism and programs lipid homeostasis impairments in the liver of rat offspring

Mazzucco, M. B., Fornes, D. D., Capobianco, E., Higa, R., Jawerbaum, A., & White, V. (2015) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2015.08.019 · Cited by 14

A Comparative Study of Mouse Hepatic and Intestinal Gene Expression Profiles under PPARαKnockout by Gene Set Enrichment Analysis

He, K., Wang, Q., Yang, Y., Wang, M., & Pan, Y. (2011) · PPAR Research · doi:10.1155/2011/629728 · Cited by 15

Effect of leptin on peroxidation and antioxidant defense in ethanol‐supplemented Mus musculus heart

Vairappan, B., & Nalini, N. (2007) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2007.00476.x · Cited by 13

Central infusion of leptin does not increase AMPK signaling in skeletal muscle of sheep

Laker, R. C., Henry, B. A., Wadley, G. D., Clarke, I. J., Canny, B. J., & McConell, G. K. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00079.2010 · Cited by 13

Adipokines in Non-Alcoholic Fatty Liver Disease

Baranova, A. V., & Younossi, Z. M. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-370-7_22 · Cited by 13

The Vicious Circle of Leptin and Obesity

Díaz, B. B., Pérez, M. D. C. R., & de León, A. C. (2006) · Current Nutrition & Food Science · doi:10.2174/157340106778699421 · Cited by 10

Astragalus mongholicus powder, a traditional Chinese medicine formula ameliorate type 2 diabetes by regulating adipoinsular axis in diabetic mice

Xu, S., Ye, B., Li, J., Dou, Y., Yu, Y., Feng, Y., Wang, L., Wan, D. C., & Rong, X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.973927 · Cited by 9

Role of Hormone-sensitive Lipase in Leptin-Promoted Fat Loss and Glucose Lowering

Takanashi, M., Taira, Y., Okazaki, S., Takase, S., Kimura, T., Li, C. C., Xu, P., Noda, A., Sakata, I., Kumagai, H., et al. (2017) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.39552 · Cited by 9

Adverse Outcome Pathway: Peroxisome Proliferator-Activated Receptor α Activation and Reproductive Toxicity—Development and Application in Assessment of Endocrine Disruptors/Reproductive Toxicants

Nepelska, M., Odum, J., & Munn, S. (2017) · Applied In Vitro Toxicology · doi:10.1089/aivt.2017.0004 · Cited by 9

Characterization of the 2-enoyl thioester reductase of mitochondrial fatty acid synthesis type II in mammals

Chen, Z. (2008) · Cited by 9

Old fat, make way for new fat

Gibbons, G. (2005) · Nature Medicine · doi:10.1038/nm0705-722 · Cited by 8

Tissue-Specific 5′ Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin

Garratt, E. S., Vickers, M. H., Gluckman, P. D., Hanson, M. A., Burdge, G. C., & Lillycrop, K. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067483 · Cited by 8

Adipokines in Nonalcoholic Fatty Liver Disease

Baranova, A. V., Birerdinc, A., & Younossi, Z. M. (2014) · Humana Press eBooks · doi:10.1007/978-1-62703-770-9_17 · Cited by 8

Associations Between Serum Leptin Levels and Transaminase Activities and the Status of Lifestyle in Japanese Workers

Yokoyama, H., Hirose, H., Ohgo, H., & Saito, I. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2004.tb03236.x · Cited by 8

Regulation of feeding and therapeutic application of bioactive peptides

Ueno, H., Zhang, W., & Nakazato, M. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108187 · Cited by 7

SerpinA3N deficiency attenuates steatosis and enhances insulin signaling in male mice

Tran, M., Mostofa, G., Picard, M., Wu, J., Wang, L., & Shin, D. (2023) · Journal of Endocrinology · doi:10.1530/joe-22-0073 · Cited by 8

Study on the Function of Leptin Nutrient Acquisition and Energy Metabolism of Zebrafish (Danio rerio)

Wu, J., Zhuang, W., Lu, K., Zhang, L., Wang, Y., Chai, F., & Liang, X. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111647 · Cited by 7

No significant effect of acute moderate alcohol intake on leptin levels in healthy male volunteers

Dammann, G., Dierkes, J., Graf, M., Wiesbeck, G. A., Pridzun, L., Schulte, T., Westphal, S., Luley, C. H., Allen, J., & Wurst, F. M. (2005) · Addiction Biology · doi:10.1080/13556210500313875 · Cited by 6

Contribution of polymorphisms in the LEP, LEPR and RETN genes on serum leptin and resistin levels in young adults from Mexico

López-Quintero, A., Garcı́a-Zapién, A. G., Flores-Martí­nez, S. E., Díaz-Burke, Y., González-Sandoval, C. E., López-Roa, R. I., Medina-Díaz, E., Almaguer, M. L. M., & Sánchez‐Corona, J. (2017) · Cellular and Molecular Biology · doi:10.14715/cmb/2017.63.8.3 · Cited by 5

Associations Between Serum Leptin Levels and Transaminase Activities and the Status of Lifestyle in Japanese Workers

Yokoyama, H., Hirose, H., Ohgo, H., & Saito, I. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000133549.77624.42 · Cited by 5

Transcriptome analysis of adipose tissue in grazing cattle: Identifying key regulators of fat metabolism

Qin, X., He, X., Chen, L., Han, Y., Yun, Y., Wu, J., Sha, L., & Borjigin, G. (2024) · Open Life Sciences · doi:10.1515/biol-2022-0843 · Cited by 4

The pathophysiological mechanism between hypopituitarism and nonalcoholic fatty liver disease

Zhang, X., Tian, H., & Li, Y. (2022) · iLiver · doi:10.1016/j.iliver.2022.02.004 · Cited by 5

Chinese yellow cattle PPARA gene: Analyses of expression, polymorphism and trait association

Chen, N., Zhang, Q., Zhi, J., Guo, H., Gao, H., Li, F., Huang, J., Lei, C., Chen, H., & Ma, Y. (2018) · Czech Journal of Animal Science · doi:10.17221/99/2017-cjas · Cited by 4

Effects of dietary supplementation with oleic acid on growth performance, dietary fat utilization, serum and intestinal lipid metabolic parameters, and enterocyte lipid droplet metabolism in Pekin ducks

Zhang, W., Tian, G., Zhang, K. Y., Bai, S. P., Ding, X. M., Wang, J. P., Xuan, Y., & Zeng, Q. F. (2025) · Poultry Science · doi:10.1016/j.psj.2025.105035 · Cited by 3

Effect of Lauric vs. Oleic Acid-Enriched Diets on Leptin Autoparacrine Signalling in Male Mice

Fernández-Felipe, J., Plaza, A., Domı́nguez, G., Pérez‐Castells, J., Cano, V., Cioni, F., Olmo, N. D., Ruiz‐Gayo, M., & Merino, B. (2022) · Biomedicines · doi:10.3390/biomedicines10081864 · Cited by 3

Maintaining Energy Balance in Health and Disease: Role of the AMP-Activated Protein Kinase

Scott, J. W. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6382-6_9 · Cited by 2

A meta-analysis study of gene expression datasets in mouse liver under PPARα knockout

He, K., Wang, Z., Wang, Q., & Pan, Y. (2013) · Genetics Research · doi:10.1017/s0016672313000098 · Cited by 2

Zespół metaboliczny - aktualny stan wiedzy o przyczynach i patomechanizmach

Pawłowska, J., Witkowski, J. M., & Bryl, E. (2009) · Via Medica Journals · Cited by 2

Do adipokines levels influence facial attractiveness of young women?

Żelaźniewicz, A., Nowak, J., Studzińska, I., & Pawłowski, B. (2020) · American Journal of Physical Anthropology · doi:10.1002/ajpa.24114 · Cited by 2

Environmental Epigenetics and Obesity: Evidences from Animal to Epidemiologic Studies

Su, L. J. (2015) · Molecular and integrative toxicology · doi:10.1007/978-1-4471-6678-8_6 · Cited by 2

Aerobic physical training after weaning improves liver histological and metabolic characteristics of diet-induced obese rats

Almeida, F. N., Salgueiro-Paradigorria, C. L., Franzói-de-Moraes, S. M., Nachbar, R. T., Chimin, P., & Natali, M. R. M. (2012) · Science & Sports · doi:10.1016/j.scispo.2012.06.003 · Cited by 2

N-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a PPARα-Dependent Manner

Neschen, S., Morino, K., Dong, J., Wang-Fischer, Y., Cline, G. W., Romanelli, A. J., Rossbacher, J. C., Moore, I. K., Regittnig, W., Muñoz, D. S., et al. (2007) · Cited by 2

Nuclear translocation of STAT3 by in vitro metreleptin administration causes lipolysis in human primary adipocytes

Choi, S. K., Park, S., & Moon, H. (2016) · Brazilian Archives of Biology and Technology · doi:10.1590/1678-4324-2016150605 · Cited by 1

Nitric Oxide and Cell Metabolism Dysfunction in the Metabolic Syndrome

Nisoli, E., & Moncada, S. (2005) · Elsevier eBooks · doi:10.1016/b978-84-8174-892-5.50018-8 · Cited by 1

2 Nutrient sensing in animal cells and integration of nutrient and endocrine signalling pathways

Proud, C. G., Hundal, H. S., & Taylor, P. M. (2004) · Topics in current genetics · doi:10.1007/978-3-540-39898-1_3 · Cited by 1

Studies of the interaction between diabetes family history, exercise, adiposity and metabolic health

Barwell, N. D. (2010) · Enlighten: Theses (The University of Glasgow) · Cited by 1

Altered lipid metabolism in rodents subjected to calorie restriction

Higami, Y., Weindruch, R. H., Prolla, T. A., & Shimokawa, I. (2004) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2004.00185.x · Cited by 1

Leptin: A Central Role in an Expanding Answer to Weight Loss

Holness, M. J. (2007) · Endocrinology · doi:10.1210/en.2007-1264 · Cited by 1

NRF2 AS A NUTRIENT SENSITIVE TRANSCRIPTION FACTOR

Kulkarni, S. R. (2012) · Digital Commons - URI (University of Rhode Island) · doi:10.23860/diss-kulkarni-supriya-2012 · Cited by 1

METABOLIC AND HORMONAL STUDIES IN SOUTH AFRICAN WOMEN OF INDIAN AND AFRICAN ORIGIN

Waisberg, R. (2010) · University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg) · Cited by 1

Regulation of human adipose tissue gene expression in relation to obesity and insulin resistance

Klimčáková, E. (2007) · OpenGrey (Institut de l'Information Scientifique et Technique)

Neonatal leptin exposure induces altered expression of specific PPARα transcripts in adipose tissue of adult rats

Lillycrop, K. A., Phillips, E. S., Vickers, M. H., Gluckamn, P., Hanson, M. A., & Burdge, G. C. (2008) · Proceedings of The Nutrition Society · doi:10.1017/s0029665108009786

Modulació farmacològica de l'oleoil-estrona sobre la ingesta i la composició corporal

Lorente, R. F. (2007) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Análisis en animales transgénicos del papel del incremento en la gliceroneogénesis o en la captación de glucosa por el tejido adiposo

Forero, M., & Antonio, S. (2006) · TDX (Tesis Doctorals en Xarxa)

Role of leptin and obesity-related leptin resistance in the pathophysiology of metabolic syndrome

Rahmouni, K., & Correia, M. (2006)

Nutritional regulation of central fat mass and obesity-associated (FTO) expression, and its association with the central melanocortin signaling in the regulation of energy homeostasis

Poritsanos, N. J. (2010) · Mspace (University of Manitoba)

Role of insulin receptor substrate 1 in energy homeostasis in vivo

Stöhr, O. (2012) · Kölner Universitäts PublikationsServer (Universität zu Köln)

The role of leptin in the regulation of glucose homeostasis

Levi, J. (2010) · cIRcle (University of British Columbia) · doi:10.14288/1.0071042

The effects of distinct fatty acids on central leptin sensitivity, hypothalamic inflammation, and central-regulated hepatic metabolism

Cheng, L. (2015) · Research Online (University of Wollongong)

[Clinical pictures of ischemic colitis].

Yamashiro, M., Kanazawa, K., Nakayama, N., Hashimoto, H., & KAGAMI, H. (1976) · PubMed

Obesity: A Complex Disease with Immune Components

Liu, Y., & Clément, K. (2017) · Wiley-VCH eBooks · doi:10.1002/9783527692156.ch46

Autocrine Effects in White Adipose Tissue and Pancreatic Islets: Emergent Roles in the Regulation of Adipocyte and Pancreatic β-cell Function

Sugden, M. C., & Holness, M. J. (2011) · Royal Society of Chemistry eBooks · doi:10.1039/9781849733434-00010

Implication of mitochondria endoplasmic-reticulum interactions in the control of hepatic metabolism

Theurey, P. (2015) · theses.fr (ABES) · doi:10.70675/c827066dz5c76z4f0azb465z409dc90bb0e5

Traitement par leptine recombinante dans les syndromes lipodystrophiques génétiques : effets sur le métabolisme glucido-lipidique

Vatier, C. (2017) · theses.fr (ABES) · doi:10.70675/c838779bzf530z488eza1b7z3f0e1185a357

Impact de l’obésité maternelle sur les fonctions placentaires : rôles de la leptine et de l'adiponectine

Nogues, P. (2019) · theses.fr (ABES) · doi:10.70675/c3ecfee5ze428z4395za563za025758f71a2

Hepatocyte PPARα is required for the sensing of adipose-derived fatty acids and for full brown adipose tissue activation during lipolysis

Fougerat, A., Schoiswohl, G., Polizzi, A., Régnier, M., Wagner, C., Smati, S., Fougeray, T., Lippi, Y., Lasserre, F., Tramunt, B., et al. (2022) · HAL

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

Fougerat, A., Schoiswohl, G., Polizzi, A., Régnier, M., Wagner, C., Smati, S., Fougeray, T., Lippi, Y., Lasserre, F., Raho, I., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110910 · Cited by 109

Peroxisome Proliferator-Activated Receptor α Mediates the Effects of High-Fat Diet on Hepatic Gene Expression

Patsouris, D., Reddy, J. K., Müller, M. M., & Kersten, S. (2005) · Endocrinology · doi:10.1210/en.2005-1132 · Cited by 346

Rapid transformation of white adipocytes into fat-oxidizing machines

Orci, L., Cook, W. S., Ravazzola, M., Wang, M.-Y., Park, B.-H., Montesano, R., & Unger, R. H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308258100 · Cited by 234

Defect in Peroxisome Proliferator-activated Receptor α-inducible Fatty Acid Oxidation Determines the Severity of Hepatic Steatosis in Response to Fasting

Hashimoto, T., Cook, W. S., Qi, C., Yeldandi, A. V., Reddy, J. K., & Rao, M. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m910350199 · Cited by 450