Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,240 · see citing works

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,512 · see citing works

G ₁ Events and Regulation of Cell Proliferation

Pardee, A. B. (1989) · Science · doi:10.1126/science.2683075 · Cited by 2,182 · see citing works

The p53 proto-oncogene can act as a suppressor of transformation

Finlay, C. A., Hinds, P. W., & Levine, A. J. (1989) · Cell · doi:10.1016/0092-8674(89)90045-7 · Cited by 1,987 · see citing works

Tumor Suppressor Genes

Weinberg, R. A. (1991) · Science · doi:10.1126/science.1659741 · Cited by 1,765 · see citing works

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

Baker, S. J., Markowitz, S. D., Fearon, E. R., Willson, J. K. V., & Vogelstein, B. (1990) · Science · doi:10.1126/science.2144057 · Cited by 1,742 · see citing works

Human Proto-Oncogene c- <i>jun</i> Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

Bohmann, D., Bos, T. J., Admon, A., Nishimura, T., Vogt, P. K., & Tjian, R. (1987) · Science · doi:10.1126/science.2825349 · Cited by 1,321 · see citing works

p53 Functions as a Cell Cycle Control Protein in Osteosarcomas

Diller, L., Kassel, J., Nelson, C. E., Gryka, M. A., Litwak, G., Gebhardt, M. C., Bressac, B., Öztürk, M., Baker, S. J., Vogelstein, B., et al. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.11.5772 · Cited by 775 · see citing works

A gene activated by growth factors is related to the oncogene v-jun.

Ryder, K., Lau, L. F., & Nathans, D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.5.1487 · Cited by 770 · see citing works

Wild-type p53 can inhibit oncogene-mediated focus formation.

Eliyahu, D., Michalovitz, D., Eliyahu, S., Pinhasi-Kimhi, O., & Oren, M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.22.8763 · Cited by 681 · see citing works

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

Mercer, W. E., Shields, M. T., Amin, M., Sauvé, G. J., Appella, E., Romano, J., & Ullrich, S. J. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.16.6166 · Cited by 477 · see citing works

Wild-type p53 can down-modulate the activity of various promoters.

Ginsberg, D., Mechta‐Grigoriou, F., Yaniv, M., & Oren, M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.22.9979 · Cited by 434 · see citing works

A c- myb Antisense Oligodeoxynucleotide Inhibits Normal Human Hematopoiesis in Vitro

Gewirtz, A. M., & Calabretta, B. (1988) · Science · doi:10.1126/science.2461588 · Cited by 424 · see citing works

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product.

Santhanam, U., Ray, A., & Sehgal, P. B. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.17.7605 · Cited by 390 · see citing works

The biology of cell reproduction

Wheals, A. E. (1985) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(85)90123-9 · Cited by 377 · see citing works

Nucleotide sequence of cloned cDNA of human c-myc oncogene

Watt, R. A., Stanton, L. W., Marcu, K. B., et al. (1983) · Nature · doi:10.1038/303725a0 · Cited by 307 · see citing works

Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb

Weston, K., & Bishop, J. M. (1989) · Cell · doi:10.1016/0092-8674(89)90405-4 · Cited by 303 · see citing works

An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.

Anfossi, G., Gewirtz, A. M., & Calabretta, B. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.9.3379 · Cited by 279 · see citing works

Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression.

Mercer, W. E., Shields, M. T., Lin, D. P., Appella, E., & Ullrich, S. J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.5.1958 · Cited by 248 · see citing works

Regulation of the proliferating cell nuclear antigen cyclin and thymidine kinase mRNA levels by growth factors.

Jaskulski, D., Gatti, C., Travali, S., et al. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)81493-x · Cited by 231 · see citing works

p53 Functions as a Cell Cycle Control Protein in Osteosarcomas

Diller, L., Kassel, J., Nelson, C. E., et al. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.11.5772-5781.1990 · Cited by 228 · see citing works

G 1 /S Transition in Normal Human T-Lymphocytes Requires the Nuclear Protein Encoded by c- myb

Gewirtz, A. M., Anfossi, G., Venturelli, D., Valpreda, S., Sims, R. B., & Calabretta, B. (1989) · Science · doi:10.1126/science.2665077 · Cited by 218 · see citing works

Isolation of human cDNA clones ofmyb-related genes, A-myband B-myb

Nomura, N., Takahashi, M., Matsui, M., Ishii, S., Date, T., Sasamoto, S., & Ishizaki, R. (1988) · Nucleic Acids Research · doi:10.1093/nar/16.23.11075 · Cited by 218 · see citing works

Gene expression during the mammalian cell cycle

Denhardt, D. T., Edwards, D. R., & Parfett, C. L. J. (1986) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(86)90024-7 · Cited by 159 · see citing works

Temperature sensitive mutants of BHK cells affected in cell cycle progression

Talavera, A., & Basilico, C. (1977) · Journal of Cellular Physiology · doi:10.1002/jcp.1040920310 · Cited by 159 · see citing works

Correlation between cell cycle duration and RNA content

Darżynkiewicz, Z., Evenson, D. P., Staiano‐Coico, L., Sharpless, T., & Melamed, M. L. (1979) · Journal of Cellular Physiology · doi:10.1002/jcp.1041000306 · Cited by 154 · see citing works

Binding of the c-myb proto-oncogene product to the simian virus 40 enhancer stimulates transcription.

Nakagoshi, H., Nagase, T., Kanei‐Ishii, C., Ueno, Y., & Ishii, S. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39793-5 · Cited by 120 · see citing works

Protooncogene expression during the cell cycle.

Kaczmarek, L. (1986) · PubMed · Cited by 114 · see citing works

DNA binding activity and transcriptional activator function of the human B-myb protein compared with c-MYB.

Mizuguchi, G., Nakagoshi, H., Nagase, T., Nomura, N., Date, T., Ueno, Y., & Ishii, S. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38844-1 · Cited by 101 · see citing works

Human wild-type p53 adopts a unique conformational and phosphorylation state in vivo during growth arrest of glioblastoma cells.

Sj, U., Mercer, W. E., & Appella, E. (1992) · PubMed · Cited by 101 · see citing works

Inhibition of T-cell proliferation by a MYB antisense oligomer is accompanied by selective down-regulation of DNA polymerase alpha expression.

Venturelli, D., Travali, S., & Calabretta, B. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.15.5963 · Cited by 97 · see citing works

Expression of the p53 protein during the cell cycle of human peripheral blood lymphocytes

Mercer, W. E., & Baserga, R. (1985) · Experimental Cell Research · doi:10.1016/0014-4827(85)90233-2 · Cited by 92 · see citing works

Wild type human p53 is antiproliferative in SV40-transformed hamster cells.

Mercer, W. E., Amin, M., Sauvé, G. J., Appella, E., Sj, U., & Romano, J. (1990) · PubMed · Cited by 91 · see citing works

Expression of thymidine kinase and dihydrofolate reductase genes in mammalian ts mutants of the cell cycle.

Liu, H. T., Gibson, C. W., Hirschhorn, R. R., et al. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83616-5 · Cited by 86 · see citing works

Molecules involved in proliferation of normal and cancer cells: presidential address.

Pardee, A. B. (1987) · PubMed · Cited by 76 · see citing works

A comparison of cell cycle-related changes in postmitotic and quiescent AF8 cells as measured by cytofluorometry after acridine orange staining.

Ashihara, T., Traganos, F., Baserga, R., et al. (1978) · PubMed · Cited by 53 · see citing works

Growth-dependent expression of human Mr 53,000 tumor antigen messenger RNA in normal and neoplastic cells.

Calabretta, B., Kaczmarek, L., Selleri, L., et al. (1986) · PubMed · Cited by 50 · see citing works

Effect of the myb gene product on expression of the PCNA gene in fibroblasts.

Travali, S., Ferbér, A., Reiss, K., et al. (1991) · PubMed · Cited by 28 · see citing works

Cell cycle analysis of human peripheral blood T lymphocytes in long-term culture

Kaczmarek, L., Calabretta, B., Elfenbein, I. B., et al. (1987) · Experimental Cell Research · doi:10.1016/0014-4827(87)90332-6 · Cited by 10 · see citing works

TPA-induction of c-fos mRNA during the cell cycle of WI-38 human fibroblasts

Calabretta, B., & Mercer, W. E. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)90989-2 · Cited by 6 · see citing works

WAF1, a potential mediator of p53 tumor suppression

El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., & Vogelstein, B. (1993) · Cell · doi:10.1016/0092-8674(93)90500-p · Cited by 8,321 · see citing works

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

Di Leonardo, A., Linke, S. P., Clarkin, K., & Wahl, G. M. (1994) · Genes &amp; Development · doi:10.1101/gad.8.21.2540 · Cited by 1,215 · see citing works

Census and evaluation of p53 target genes

Fischer, M. (2017) · Oncogene · doi:10.1038/onc.2016.502 · Cited by 971 · see citing works

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

Agarwal, M. L., Agarwal, A., Taylor, W. R., & Stark, G. R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.18.8493 · Cited by 858 · see citing works

p53 represses ribosomal gene transcription

Budde, A., & Grummt, I. (1999) · Oncogene · doi:10.1038/sj.onc.1202402 · Cited by 157 · see citing works

Proteolytic Cleavage of the mdm2 Oncoprotein during Apoptosis

Chen, L., Marechal, V., Moreau, J., Levine, A. J., & Chen, J. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.36.22966 · Cited by 121 · see citing works

Wild-Type Human p53 Transactivates the Human Proliferating Cell Nuclear Antigen Promoter

Shivakumar, C. V., Brown, D. R., Deb, S., & Deb, S. P. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.12.6785 · Cited by 120 · see citing works

p53 can repress transcription of cell cycle genes through a p21^WAF1/CIP1-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements

Quaas, M., Müller, G. A., & Engeland, K. (2012) · Cell Cycle · doi:10.4161/cc.22917 · Cited by 107 · see citing works

Structural Properties of Polyphenols Causing Cell Cycle Arrest at G1 Phase in HCT116 Human Colorectal Cancer Cell Lines

Shin, S. Y., Yoon, H. S., Ahn, S., Kim, D. W., Bae, D., Koh, D., Lee, Y. H., & Lim, Y. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140816970 · Cited by 36 · see citing works

G1 versus G2 cell cycle arrest after adriamycin‐induced damage in mouse Swiss3T3 cells

Siu, W. Y., Yam, C. H., & Poon, R. Y. C. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01481-7 · Cited by 52 · see citing works

Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronised cell cycle progression in human cell culturePreprint

Trotter, E. W., & Hagan, I. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.04.187625 · Cited by 1 · see citing works

Effect of Marsdenia tenacissima extract on G2/M cell cycle arrest by upregulating 14-3-3σ and downregulating c-myc in vitro and in vivo

Sun, L., Ain, Q. U., Gao, Y., Khan, G. J., Yuan, S., & Roy, D. (2019) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2019.03.002 · Cited by 3 · see citing works

Involvement of Mcl1 in diallyl disulfide-induced G2/M cell cycle arrest in HL-60 cells

Su, Q. (2012) · Oncology Reports · doi:10.3892/or.2012.1704 · Cited by 11 · see citing works