Cited by 309HIV Research and TreatmentHIV/AIDS drug development and treatmentEvolution and Genetic Dynamics

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation

Open access

Temin, H M·1993·Proceedings of the National Academy of Sciences

Open this paper in CoChat — free account

Abstract

Human immunodeficiency virus variation is extensive and is based on numerous mistakes in reverse transcription. All retrovirus replication requires two strand transfers (growing point jumps) to synthesize the complete provirus. I propose that the numerous mistakes in reverse transcription are the result of this requirement for the two strand transfers needed to form the provirus.

Integrity signals

Registry

Crossref · 10.1073/pnas.90.15.6900

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Frameshift Mutations and the Genetic Code
Streisinger, G., Okada, Y., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., & Inouye, M. (1966) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1966.031.01.014 · Cited by 1,400
The accuracy of reverse transcriptase from HIV-1
Roberts, J. D., Bebenek, K., & Kunkel, T. A. (1988) · Science · doi:10.1126/science.2460925 · Cited by 997
Die Molekularbiologie der Tumorviren
Sauer, G. (1977) · Die Naturwissenschaften · doi:10.1007/bf00483548 · Cited by 943
Fidelity of HIV-1 reverse transcriptase
Preston, B. D., Poiesz, B. J., & Loeb, L. A. (1988) · Science · doi:10.1126/science.2460924 · Cited by 931
Structure, Replication, and Recombination of Retrovirus Genomes: Some Unifying Hypotheses
Coffin, J. M. (1979) · Journal of General Virology · doi:10.1099/0022-1317-42-1-1 · Cited by 519
Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination.
Hu, W. S., & Temin, H. M. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1556 · Cited by 476
Self-citation
Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera
Albert, J., Abrahamsson, B., Nagy, K., Aurelius, E., Gaines, H., Nyström, G., & Fenyõ, É. M. (1990) · AIDS · doi:10.1097/00002030-199002000-00002 · Cited by 398
Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase
Peliska, J. A., & Benkovic, S. J. (1992) · Science · doi:10.1126/science.1279806 · Cited by 335
Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase
Bębenek, K., Abbotts, J., Roberts, J. D., Wilson, S. H., & Kunkel, T. A. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)84799-3 · Cited by 311
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.
Mendelman, L. V., Petruska, J. A., & Goodman, M. F. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39981-8 · Cited by 290

Flagged first, then by citations

Show all 37 references

Sorted by citations

Items 201–300 of 309

Cellular Aspects of HIV Infection
(2001) · Wiley eBooks · doi:10.1002/047122393x · Cited by 10
A Pairing-Looping Model for Position-Effect Variegation in Drosophila
Henikoff, S. (1996) · Stadler genetics symposia series · doi:10.1007/978-1-4899-0280-1_15 · Cited by 10
Intersubtype Recombinant HIV Type 1 Involving HIV-MAL-Like and Subtype H-Like Sequence in Four Norwegian Cases
Jonassen, T. Ø., Grinde, B., Åsjö, B., Hasle, G., & Hungnes, O. (2000) · AIDS Research and Human Retroviruses · doi:10.1089/088922200309593 · Cited by 10
Viral Sequence Analysis from HIV-Infected Mothers and Infants: Molecular Evolution, Diversity, and Risk Factors for Mother-To-Child Transmission
Bulterys, P. L., Dalai, S. C., & Katzenstein, D. A. (2010) · Clinics in Perinatology · doi:10.1016/j.clp.2010.08.003 · Cited by 9
Looking ultra deep: Short identical sequences and transcriptional slippage
Ritz, K., van Schaik, B. D. C., Jakobs, M. E., Aronica, E., Tijssen, M. A. J., van Kampen, A. H. C., & Baas, F. (2011) · Genomics · doi:10.1016/j.ygeno.2011.05.005 · Cited by 8
Resistance to Anti-Human Immunodeficiency Virus Therapeutic Agents
Emini, E. A. (1995) · Springer eBooks · doi:10.1007/978-1-4757-9203-4_16 · Cited by 9
Intrapatient Variability of HIV Type 1 Group O ANT70 during a 10-Year Follow-up
Janssens, W., Nkengasong, J. N., Heyndríckx, L., der Auwera, G. V., Vereecken, K., Coppens, S., Willems, B., Beirnaert, E., Fransen, K., Peeters, M., et al. (1999) · AIDS Research and Human Retroviruses · doi:10.1089/088922299310025 · Cited by 9
Mismatch Extension During Strong Stop Strand Transfer and Minimal Homology Requirements for Replicative Template Switching During Moloney Murine Leukemia Virus Replication
Marr, S. K., & Telesnitsky, A. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00597-7 · Cited by 9
Mechanism Analysis Indicates that Recombination Events in HIV-1 Initiate and Complete Over Short Distances, Explaining Why Recombination Frequencies Are Similar in Different Sections of the Genome
Rigby, S. T., Rose, A. E., Hanson, M. N., & Bambara, R. A. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.02.029 · Cited by 8
Human immunodeficiency virus type-1 (HIV-1) subtypes in Jamaica
Heslop, O. D., Smikle, M. F., Deer, D., Christian, N., Vickers, I. E., Harvey, K. M., Figueroa, J. P., Christie, C. D. C., Bain, B., & Barton, E. N. (2005) · West Indian Medical Journal · doi:10.1590/s0043-31442005000500002 · Cited by 8
Evidence for the acquisition of multi-drug resistance in an HIV-1 clinical isolate via human sequence transduction
Takebe, Y., & Telesnitsky, A. (2006) · Virology · doi:10.1016/j.virol.2006.05.009 · Cited by 8
Molecular Epidemiology of Human Immunodeficiency Virus
Chin, B. S. (2017) · Infection and Chemotherapy · doi:10.3947/ic.2017.49.1.1 · Cited by 8
Mutagenesis by human immunodeficiency virus reverse transcriptase: Incorporation of O6-methyldeoxyguanosine triphosphate
Hizi, A., Kamath‐Loeb, A. S., Rose, K. D., & Loeb, L. A. (1997) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(96)00217-5 · Cited by 8
Human immunodeficiency virus reverse transcriptase base misincorporations can promote strand transfer
Diaz, L., Cristofaro, J. V., & DeStefano, J. J. (2000) · Archives of Virology · doi:10.1007/s007050070113 · Cited by 8
Selection and characterization of replication-competent revertants of a Rous sarcoma virus src gene oversplicing mutant
Zhang, L., Simpson, S., & Stoltzfus, C. M. (1996) · Journal of Virology · doi:10.1128/jvi.70.6.3636-3644.1996 · Cited by 8
Forensic Investigation of a 1986 Outbreak of Osteopetrosis in Commercial Brown Layers Reveals a Novel Avian Leukosis Virus–Related Genome
Barbosa, T., Ramirez, M., Hafner, S., Cheng, S., & Zavala, G. (2010) · Avian Diseases · doi:10.1637/9138-111209-reg.1 · Cited by 7
Transposable Elements and their Use for Target Site Specific Gene Delivery
Buzdin, A. A. (2006) · Current Pharmacogenomics · doi:10.2174/157016006776055437 · Cited by 7
Formation of template-switching artifacts by linear amplification.
Chakravarti, D., & Mailander, P. C. (2008) · PubMed Central · Cited by 7
Effects of Identity Minimization on Moloney Murine Leukemia Virus Template Recognition and Frequent Tertiary Template-Directed Insertions during Nonhomologous Recombination
Duggal, N. K., Goo, L., King, S. R., & Telesnitsky, A. (2007) · Journal of Virology · doi:10.1128/jvi.01591-07 · Cited by 6
Expression profiling of mRNA obtained from single identified crustacean motor neurons: determination of specificity of hybridization
Pekhletski, R., Cooper, R. L., Atwood, H. L., & Hampson, D. R. (1996) · Invertebrate Neuroscience · doi:10.1007/bf02211914 · Cited by 6
Genomic characterization of a new CRF01_AE/CRF07_BC case from a MSM patient in Guangdong, China
Huang, X., Yu, G., Zheng, C., Zhou, P., Anderson, C., Zhao, J., Lam, T. T., Li, Y., Chen, L., Lin, P., et al. (2021) · Journal of Medical Virology · doi:10.1002/jmv.26799 · Cited by 6
Design and Preparation of Recombinant Antigens as Diagnostic Reagents in Solid-Phase Immunosorbent Assays
Warnes, A., Fooks, A. R., & Stephenson, J. R. (2004) · Humana Press eBooks · doi:10.1385/1-59259-679-7:373 · Cited by 6
Prevalence and determinants of HIV-1 subtypes in Canada: enhancing routinely collected information through the Canadian HIV Strain and Drug Resistance Surveillance Program.
Jayaraman, G., Gleeson, T. D., Ml, R., Cook, D. A., Preiksaitis, J. K., Sidaway, F., Harmen, S., Dawood, M. R., Wood, M., Ratnam, S., et al. (2003) · PubMed · Cited by 6
Evolution of the HIV-1 V3 region in the Italian epidemic.
Buonaguro, L., Tagliamonte, M., Tornesello, M. L., & Buonaguro, L. (2007) · PubMed · Cited by 6
High fidelity of homologous retroviral recombination in cell culture
Bircher, L. A., Rigano, J. C., Ponferrada, V. G., & Wooley, D. P. (2002) · Archives of Virology · doi:10.1007/s00705-002-0843-1 · Cited by 5
Each genomic RNA in HIV-1 heterozygous virus generate new virions
Iglesias-Sánchez, M. J., & López‐Galíndez, C. (2005) · Virology · doi:10.1016/j.virol.2004.12.027 · Cited by 5
A Computational Model for Predicting RNase H Domain of Retrovirus
Wu, S., Zhang, X., & Han, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161913 · Cited by 5
Development of physical forms of unintegrated retroviral DNA in mouse spinal cord tissue during ts1-induced spongiform encephalomyelopathy: elevated levels of a novel single-stranded form in paralyzed mice
Szurek, P. F., & Brooks, B. R. (1995) · Journal of Virology · doi:10.1128/jvi.69.1.348-356.1995 · Cited by 5
Retroviral Vector Design for Cancer Gene Therapy
Baum, C., Ostertag, W., von Laer, D., & Stocking, C. (2002) · Elsevier eBooks · doi:10.1016/b978-012437551-2/50002-1 · Cited by 5
HIV Resistance to Antagonists of Viral Reverse Transcriptase
Wainberg, M. A. (1999) · Elsevier eBooks · doi:10.1016/b978-012200741-5/50016-7 · Cited by 5
DNA Polymerases: Reverse Transcriptase Integrase, and Retrovirus Replication
Andréola, M., Parissi, V., & Litvak, S. (2013) · Encyclopedia of Biological Chemistry · doi:10.1016/b978-0-12-378630-2.00258-9 · Cited by 5
Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication
Jehad, M. A., Ali, L. M., Pillai, V. N., Prabhu, S. G., Mustafa, F., & Rizvi, T. A. (2026) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaf066 · Cited by 5
“Irrespective of the nature of the first strand transfer to be intramolecular, intermolecular, or random, they all are likely to contribute toward genetic variation among retroviruses during DNA synthesis, owing to the numerous errors occurring during reverse transcription (Temin 1993 ).”
Structural variability of Tvv1 grapevine retrotransposons can be caused by illegitimate recombination
Moisy, C., Blanc, S., Merdinoglu, D., & Pelsy, F. (2008) · Theoretical and Applied Genetics · doi:10.1007/s00122-007-0700-4 · Cited by 4
A polymerase-site-jumping model for strand transfer during DNA synthesis by reverse transcriptase
Xie, P. (2009) · Virus Research · doi:10.1016/j.virusres.2009.03.022 · Cited by 4
Random strand transfer recombination (RSTR) for homology-independent nucleic acid recombination
Reiter, B. E., Faschinger, A., Glieder, A., & Schwab, H. (2006) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2006.10.002 · Cited by 4
An Array of Novel Murine Spleen Focus-Forming Viruses That Activate the Erythropoietin Receptor
Gómez‐Lucía, E., Zhi, Y., Nabavi, M., Zhang, W., Kabat, D., & Hoatlin, M. E. (1998) · Journal of Virology · doi:10.1128/jvi.72.5.3742-3750.1998 · Cited by 4
Truncated oncoproteins of retroviruses and hepatitis B virus: A lesson in contrasts
Minárovits, J., & Niller, H. H. (2019) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2019.05.020 · Cited by 4
MORBIDITY AND MORTALITY OF HAWAIIAN GEESE (BRANTA SANDVICENSIS) AND LAYSAN ALBATROSS (PHOEBASTRIA IMMUTABILIS) ASSOCIATED WITH RETICULOENDOTHELIOSIS VIRUS
Work, T. M., Breeden, R., Dagenais, J., Rameyer, R. A., Sellers, H. S., Ip, H. S., & Casey, J. W. (2022) · Journal of Wildlife Diseases · doi:10.7589/jwd-d-21-00164 · Cited by 3
A Model of Non-Homologous Recombination Mediated by HIV-1 Reverse Transcriptase Explaining Sequence Motif Duplications That Confer a Replication Fitness Advantage
Panchapakesan, A., & Ranga, U. (2025) · Viruses · doi:10.3390/v17050680 · Cited by 5
Two RNA Worlds: Toward the Origin of Replication, Genes, Recombination, and Repair
Lankenau, D. (2011) · Springer eBooks · doi:10.1007/978-3-642-21625-1_11 · Cited by 3
Mechanistic insights into the roles of three linked single-stranded template binding residues of MMLV reverse transcriptase in misincorporation and mispair extension fidelity of DNA synthesis
Xie, J. P., Zhang, P., Li, C., Huang, Q., Zhou, R., & Peng, T. (2011) · Gene · doi:10.1016/j.gene.2011.02.007 · Cited by 3
Evolution of nef variants in gut associated lymphoid tissue of rhesus macaques during primary simian immunodeficiency virus infection
Ndolo, T., Syvanen, M., Ellison, T. J., & Dandekar, S. (2005) · Virology · doi:10.1016/j.virol.2005.08.013 · Cited by 3
Conflicting selection pressures on T-cell epitopes in HIV-1 subtype B
Irausquin, S., & Hughes, A. L. (2011) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2010.12.011 · Cited by 3
Decreased Virus Population Diversity in p53 -Null Mice Infected with Weakly Oncogenic Abelson Virus
Marchlik, E., Kalman, R., & Rosenberg, N. E. (2005) · Journal of Virology · doi:10.1128/jvi.79.18.11618-11626.2005 · Cited by 3
Identifying RNA Recombination Events and Non-covalent RNA–RNA Interactions with the Molecular Colony Technique
Chetverina, H. V., & Chetverin, A. B. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1896-6_1 · Cited by 3
An internal deletion enhances the transcriptional activity of a recombinant retrovirus in hematopoietic cells in vivo
MacKenzie, K. L., Bonham, L., & Symonds, G. P. (1994) · Journal of Virology · doi:10.1128/jvi.68.11.6924-6932.1994 · Cited by 3
Reviewing Science in an Information-Overloaded World
Noguchi, J. (2009) · Palgrave Macmillan UK eBooks · doi:10.1057/9780230244290_3 · Cited by 2
Evolutionarily recent groups of transposable elements in the human genome
Baskaev, K. K., & Buzdin, A. A. (2011) · Russian Journal of Genetics Applied Research · doi:10.1134/s2079059711060049 · Cited by 2
Using RT-prone recombination to promote re-building of complete retroviral vectors from two defective precursors: Low efficiency and sequence specificities
Bru, T., Galetto, R., Piver, É., Collin, C., Negroni, M., & Pagès, J. (2007) · Journal of Virological Methods · doi:10.1016/j.jviromet.2007.01.022 · Cited by 2
May Phylogenetic Analysis Support Epidemiological Investigation in Identifying the Source of HIV Infection?
Ciccozzi, M., Presti, A. L., Cenci, A., Staltari, O., Buttò, S., Equestre, M., Ciccaglione, A. R., Caroleo, B., Rezza, G., & Guadagnino, V. (2010) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2010.0189 · Cited by 2
Large Multidomain Protein NMR: HIV-1 Reverse Transcriptase Precursor in Solution
Ilina, T. V., Xi, Z., Brosenitsch, T. A., Sluis‐Cremer, N., & Ishima, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249545 · Cited by 2
Molecular mechanisms of HIV-1 genetic diversity
Сосин, Д. В., & Tchurikov, N. A. (2017) · Molecular Biology · doi:10.1134/s0026893317030153 · Cited by 3
Strand transfer to the 5′ part of a tRNA as a mechanism for retrovirus patch-repair recombination in vivo
Carrasco, M. L., Duch, M., & Pedersen, F. S. (2004) · Journal of General Virology · doi:10.1099/vir.0.79816-0 · Cited by 2
Diverse Cross-Reactive Potential and Vβ Gene Usage of an Epitope-Specific Cytotoxic T-Lymphocyte Population in Monkeys Immunized with Diverse Human Immunodeficiency Virus Type 1 Env Immunogens
Hulot, S. L., Seaman, M. S., Sen, P., Autissier, P., Manuel, E. R., & Letvin, N. L. (2009) · Journal of Virology · doi:10.1128/jvi.00776-09 · Cited by 2
Repeated Template Switching: Obstacles in cDNA Libraries and Ways to Avoid Them
Villányi, Z. (2012) · The Open Genomics Journal · doi:10.2174/1875693x01205010001 · Cited by 1
Diversity within the Immunodominant Epitopes of Envelope gp41 HIV-1 in Kenya and Its Effects on Performance of the HIV-1 Antibody-Based Detection Kits
Kimotho, J. H. (2015) · American Journal of Internal Medicine · doi:10.11648/j.ajim.20150301.13 · Cited by 1
From Simian to Human Immunodeficiency Viruses (SIV to HIV)
Tebit, D. M., & Arts, E. J. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-405191-1.00009-0 · Cited by 1
Performance of rapid subtyping tools used for the classification of HIV type 1 recombinants isolated from selected countries in west and central Africa
Bimela, J. S., Torimiro, J. N. E., Atogho, T. B., Tchapda, L., Fokam, J., Takou, D., & Mbacham, W. F. (2016) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2016.15554 · Cited by 1
МОЛЕКУЛЯРНЫЕ МЕХАНИЗМЫ ГЕНЕТИЧЕСКОЙ ИЗМЕНЧИВОСТИ ВИЧ-1, "Молекулярная биология"
Сосин, Д. В., & Churikov, N. A. (2017) · Molecular Biology · doi:10.7868/s0026898417030156 · Cited by 1
THE ROLE OF EARLY CYTOTOXIC LYMPHOCYTE (CTL) ESCAPE IN THE PATHOGENESIS OF HIV-1 SUBTYPE C INFECTION
Ntale, R. S. (2012) · Open University of Cape Town (University of Cape Town) · Cited by 1
Studies of the pathogenesis of Jembrana disease virus infection in Bos javanicus
Tenaya, I. W. M. (2010) · Murdoch University Research Portal · Cited by 1
Molecular and immunogenic analysis of Jembrana disease virus Tat
Setiyaningsih, S. (2006) · Murdoch University Research Portal · Cited by 1
Análise e caracterização molecular, estrutural e populacional de proteases de HIV-1 do Estado de São Paulo.
Iamarino, A. (2012) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2012.tde-13112012-083943 · Cited by 1
Novel Inhibitors of HIV-Reverse Transcriptase Catalyzed DNA Strand Transfer: Can We Alter the Infidelity of the Enzyme?
Suleman, A. S., Tillekeratne, L. M. V., & Hudson, R. A. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4875 · Cited by 1
Use of persistent infections with vaccinia virus recombinants to introduce alterations in foreign proteins: An application to HIV-1 env protein
Estéban, M., Rodríguez, J. R., Jiménez, V., & Rodrı́guez, D. (1996) · Virus Research · doi:10.1016/s0168-1702(96)01380-9 · Cited by 1
Effect of Human Immunodeficiency Virus on the Outcome of Hepatitis C Virus Infection
Idılman, R., Colantoni, A., Maria, N. D., Harig, J. M., & Thiel, D. H. V. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655201750074410 · Cited by 1
Functional Viral Metagenomics and the Development of New Enzymes for DNA and RNA Amplification and Sequencing
Schoenfeld, T. W., Hermersmann, N., Moser, M., Sugar, D. R., Dhodda, V. K., & Mead, D. A. (2011) · Wiley eBooks · doi:10.1002/9781118010549.ch53
Factors That Promote Recombination during HIV-1 Reverse Transcription and Properties of M184 Drug Resistant Reverse Transcriptases
Gao, L. (2009) · UR Research (University of Rochester)
Molecular Therapeutics in Hematology
Stewart, A. K., & Medin, J. A. (2005) · doi:10.1002/9780470987063.ch23
Improved methods for production and characterisation of Jembrana disease virus proteins
Rachmat, J. (2010) · Murdoch University Research Portal
Viral variation of the bovine immunodeficiency-like virus
Suarez, D. L. (1995) · doi:10.31274/rtd-180813-9979
Characterisation of llama antibody fragments able to act as HIV-1 entry inhibitors
Quigley, A. F. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)
Design of a dynamic model of genes with multiple autonomous regulatory modules by evolution in silicoPreprint
Spirov, A. V., & Holloway, D. M. (2010) · Nature Precedings · doi:10.1038/npre.2010.3913.2
Sixteenth Midwest Enzyme Chemistry Conference
Viola, R. E. (1997) · Bioorganic Chemistry · doi:10.1006/bioo.1996.1048
Drug Resistance Mutations in HIV Patients on Antiretroviral Therapy in Ghana
Bonney, E. Y. (2013)
Phylogenetic analysis of HIV-1 in Mpumalanga
Msimanga, P. (2013) · SUNScholar (Stellenbosch University)
Sero-prevalance of anti-R7V antibody in HIV infected patients in the Federal Capital Territory (FCT), Nigeria
Shugaba, A., & Agwale, S. M. (2010) · AFRICAN JOURNAL OF BIOTECHNOLOGY
Simian immunodeficiency virus (SIV) molecular epidemiology in non-human primates from West Africa
Locatelli, S. (2008) · edoc (University of Basel) · doi:10.5451/unibas-004524577
An epidemiological investigation to reconstruct a probable human immunodeficiency virus -1 transmission network: a case report
Serafino, S., Cella, E., Montagna, C., Cavallari, E. N., Vittozzi, P., Presti, A. L., Giovanetti, M., Mazzuti, L., Turriziani, O., Ceccarelli, G., et al. (2015) · Journal of Medical Case Reports · doi:10.1186/s13256-015-0717-2
Recent Inserts of Transposable Elements Affect Structure and Functions of Human Genome
Buzdin, A. A., Suntsova, M., Bantysh, O., Aleksandrova, E., Zabolotneva, A., Gogvadze, E. V., & Гайфуллин, Н. (2011) · NATO science for peace and security series. C, Environmental security · doi:10.1007/978-94-007-1939-2_23
Characterization of HIV specific T cell responses during acute and early HIV-1 subtype C infection
Mlotshwa, M. (2014) · University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg)
Tracking HIV-1 genetic variation: recombination and N-linked glycosylation sites
Zhang, M. (2007) · doi:10.53846/goediss-1312
Análise e Caracterização Molecular, Estrutural e Populacional de Proteases de HIV-1 do Estado de São Paulo
Microbiologia, G. E. (2012)
Vollständige Genomanalyse einer neuen rekombinanten Form von HIV-1 aus Oman
Fakultät, N. (2014)
A Molecular Approach to Nested RT-PCR Using a New Set of Primers for the Detection of the Human Immunodeficiency Virus Protease Gene
Zarei, M., Ravanshad, M., Bagban, A., & Fallahi, S. (2016) · Jundishapur Journal of Microbiology · doi:10.5812/jjm.30365 · Cited by 1
HIV-1 EVOLUTION: ROLE OF DIVERSITY AND FITNESS—IMPLICATIONS FOR THE EPIDEMIC
Nankya, I. (2010) · OhioLink ETD Center (Ohio Library and Information Network)
Solution NMR studies of HIV-1 reverse transcriptase
Sharaf, N. G. (2017) · D-Scholarship@Pitt (University of Pittsburgh)
Genetic diversity and phenotypic characterization of HIV-1 circulating recombinant forms (CRFs) among drug-naive and -exposed patients in Burkina Faso
Sathiandee, K. (2009) · heiDOK (Heidelberg University) · doi:10.11588/heidok.00010109
Molecular Epidemiology of Human Immunodeficiency Virus Type 1 (HIV-1) in Southern Africa and Northern California
Dalai, S. C. (2017) · eScholarship (California Digital Library)
Detection of positive selection resulting from Nevirapine treatment in longitudinal HIV-1 reverse transcriptase sequences
Ketwaroo, B. F. K. (2006) · UWC Research Repository (University of the Western Cape)
Design of a dynamic model of genes with multiple autonomous regulatory modules by evolution in silicoPreprint
Spirov, A. V., & Holloway, D. M. (2010) · Nature Precedings · doi:10.1038/npre.2009.3913
Reverse Transcriptase and Retroviral Replication
Tarrago‐Litvak, L., Andréola, M., & Litvak, S. (2004) · Encyclopedia of Biological Chemistry · doi:10.1016/b0-12-443710-9/00178-2
Structural determinants of murine leukemia virus reverse transcriptase that are important for template switching, fidelity, and drug resistance
Svarovskaia, E. S. (2000) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.1239
Estudo da co-infecção pelo HIV e HTLV em Angola
da Silva, R. D. F. C. F. (2008)
Structural determinants of murine leukemia virus (MLV) reverse transcriptase (RT) important for fidelity and drug resistance in vivo
Halvas, E. K. (2000) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.1231
Design of a dynamic model of genes with multiple autonomous regulatory modules by evolution in silicoPreprint
Spirov, A. V., & Holloway, D. M. (2009) · Nature Precedings · doi:10.1038/npre.2009.3913.1
Estudio de la dinámica de la infección perinatal con BLV en un rodeo de tambo de alta prevalencia
Gutiérrez, G. (2010) · Repositorio Digital Institucional de la Universidad de Buenos Aires (Universidad de Buenos Aires)
Investigation of the effects of virus integration on host gene expression in mouse tumour samples
Osejindu, E. (2011) · Brunel University Research Archive (BURA) (Brunel University London)
Estudi de l’evolució de l’envolta del VIH-1 en pacients infectats sotmesos a vacunació terapèutica amb virus autòleg inactivat
Matarin, M. G. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Reconnaissance de variants d'un épitope viral par des lymphocytes T CD8+ induits par la vaccination de singes rhésus
Hulot, S. L. (2010) · theses.fr (ABES) · doi:10.70675/eda3f644z13caz4808z8050ze1fb76240683

Authors: Temin, H. M.
Affiliations: University of Wisconsin–Madison (US)
Corresponding author: Temin, H M
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 1993-08
Volume: 90
Issue: 15
Pages: 6900-6903
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.90.15.6900
PMC: PMC47042
OpenAlex: W2087946368
Cited by: 309
References: 37
Citations by year: 2026: 2 · 2025: 3 · 2022: 1 · 2021: 1 · 2020: 4 · 2019: 4 · 2018: 1 · 2017: 7 · 2016: 6 · 2015: 3 · 2014: 4 · 2013: 7 · 2012: 7
FWCI: 6.91
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5p30ca007175-36)
U.S. Public Health Service (CA-07175)
National Cancer Institute (CA-22443, CA-07175, P01CA022443)
Topics: Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Keywords: strand transfer, human immunodeficiency virus, growing points, retroviral replication
MeSH terms: Mutation, Recombination, Genetic, Retroviridae, RNA-Directed DNA Polymerase, RNA, Viral, Templates, Genetic, Genetic Variation, Virus Replication, Sequence Deletion

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks