Mechanism of Protein Modification by Glyoxal and Glycolaldehyde, Reactive Intermediates of the Maillard Reaction

Aminoguanidine Prevents Diabetes-Induced Arterial Wall Protein Cross-Linking

Brownlee, M., Vlassara, H., Kooney, A., Ulrich, P. C., & Cerami, A. (1986) · Science · doi:10.1126/science.3487117 · Cited by 1,146

Protein glycation and oxidative stress in diabetes mellitus and ageing

Wolff, S. P., Jiang, Z. Y., & Hunt, J. V. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90040-a · Cited by 886

Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

Ahmed, M. U., Thorpe, S. R., & Baynes, J. W. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)89188-3 · Cited by 864

Fructosamine: A new approach to the estimation of serum glycosylprotein. An index of diabetic control

Johnson, R. N., Metcalf, P., & Baker, J. R. (1983) · Clinica Chimica Acta · doi:10.1016/0009-8981(83)90078-5 · Cited by 763

O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

Benson, J. R., & Hare, P. E. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.2.619 · Cited by 738

New Aspects of the Maillard Reaction in Foods and in the Human Body

Ledl, F., & Schleicher, E. D. (1990) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199005653 · Cited by 738

Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors

Grandhee, S. K., & Monnier, V. M. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99006-x · Cited by 459

Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.

McCance, D. R., Dyer, D. G., Dunn, J. A., Bailie, K., Thorpe, S. R., Baynes, J., & Lyons, T. J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116482 · Cited by 444

Age-dependent accumulation of N.epsilon.-(carboxymethyl)lysine and N.epsilon.-(carboxymethyl)hydroxylysine in human skin collagen

Dunn, J. A., McCance, D. R., Thorpe, S. R., Lyons, T. J., & Baynes, J. (1991) · Biochemistry · doi:10.1021/bi00219a007 · Cited by 304

Oxidation of glycated proteins: age-dependent accumulation of N.epsilon.-(carboxymethyl)lysine in lens proteins

Dunn, J. A., Patrick, J. S., Thorpe, S. R., & Baynes, J. (1989) · Biochemistry · doi:10.1021/bi00450a033 · Cited by 250

Relevance of oxidative and carbonyl stress to long-term uremic complications

Miyata, T., Kurokawa, K., & de Strihou, C. V. Y. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.07615.x · Cited by 119

Apoptosis in ischemic renal injury: Roles of GTP depletion and p53

Dagher, P. C. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.761_7.x · Cited by 118

Respiratory and Olfactory Cytotoxicity of Inhaled 2,3-Pentanedione in Sprague-Dawley Rats

Hubbs, A. F., Cumpston, A. M., Goldsmith, W. T., Battelli, L. A., Kashon, M. L., Jackson, M. C., Frazer, D. G., Fedan, J. S., Goravanahally, M. P., Castranova, V., et al. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.05.021 · Cited by 119

Effects of the Reactive Oxygen Species Hydrogen Peroxide and Hypochlorite on Endothelial Nitric Oxide Production

Jaimes, E. A., Sweeney, C., & Raij, L. (2001) · Hypertension · doi:10.1161/hyp.38.4.877 · Cited by 112

Advanced glycation end products as biomarkers and gerontotoxins – A basis to explore methylglyoxal-lowering agents for Alzheimer’s disease?

Krautwald, M., & Münch, G. W. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.03.001 · Cited by 116

Isolation and Characterization of Glyoxal−Arginine Modifications

Glomb, M. A., & Lang, G. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf001082d · Cited by 109

Identification of α-dicarbonyl scavengers for cellular protection against carbonyl stress

Wondrak, G. T., Cervantes-Laurean, D., Roberts, M. J., Qasem, J. G., Kim, M., Jacobson, E. L., & Jacobson, M. K. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00915-7 · Cited by 108

Increased accumulation of the glycoxidation product Nε-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody

Schalkwijk, C. G., Baidoshvili, A., Stehouwer, C. D. A., van Hinsbergh, V. W. M., & Niessen, H. W. M. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2003.07.002 · Cited by 107

Immunological Evidence for Methylglyoxal-derived Modifications in vivo

Shamsi, F. A., Partal, A. E., Sady, C., Glomb, M. A., & Nagaraj, R. H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.12.6928 · Cited by 105

Extending the Spectrum of α-Dicarbonyl Compounds in Vivo

Henning, C., Liehr, K., Girndt, M., Ulrich, C., & Glomb, M. A. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.563593 · Cited by 104

Role of protein-bound carbonyl groups in the formation of advanced glycation endproducts

Liggins, J., & Furth, A. J. (1997) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/s0925-4439(97)00023-9 · Cited by 103

Triosidines: novel Maillard reaction products and cross-links from the reaction of triose sugars with lysine and arginine residues

Tessier, F. J., Monnier, V. M., Sayre, L. M., & Kornfield, J. A. (2003) · Biochemical Journal · doi:10.1042/bj20020668 · Cited by 102

Longitudinal determination of skin collagen glycation and glycoxidation rates predicts early death in C57BL/6NNIA mice

Sell, D. R., Kleinman, N. R., & Monnier, V. M. (2000) · The FASEB Journal · doi:10.1096/fasebj.14.1.145 · Cited by 100

Reactive carbonyl compounds related uremic toxicity (“carbonyl stress”)

Miyata, T., Sugiyama, S., Saitō, A., & Kurokawa, K. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.59780025.x · Cited by 99

Enzymatic Catalysis of Proton Transfer at Carbon: Activation of Triosephosphate Isomerase by Phosphite Dianion

Amyes, T. L., & Richard, J. P. (2007) · Biochemistry · doi:10.1021/bi700409b · Cited by 99

Analysis of advanced glycation endproducts in dairy products by isotope dilution liquid chromatography–electrospray tandem mass spectrometry. The particular case of carboxymethyllysine

Delatour, T., Hegele, J., Parisod, V., Richoz, J., Maurer, S., Steven, M., & Buetler, T. M. (2009) · Journal of Chromatography A · doi:10.1016/j.chroma.2009.01.011 · Cited by 98

Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy

Chakrabarti, S., Cukiernik, M., Hileeto, D., Evans, T., & Chen, S. (2000) · Diabetes/Metabolism Research and Reviews · doi:10.1002/1520-7560(0000)9999:9999 · Cited by 97

Carbonyl Stress in the Pathogenesis of Diabetic Nephropathy.

SUZUKI, D., & Miyata, T. (1999) · Internal Medicine · doi:10.2169/internalmedicine.38.309 · Cited by 99

Glycated Reconstructed Human Skin as a Platform to Study the Pathogenesis of Skin Aging

Pennacchi, P. C., de Almeida, M. E. S., Gomes, O. L. A., Faião‐Flores, F., Crepaldi, M. C. D. A., dos Santos, M. F., Barros, S. B. D. M., & Maria–Engler, S. S. (2015) · Tissue Engineering Part A · doi:10.1089/ten.tea.2015.0009 · Cited by 96

Cellular Signaling and Potential New Treatment Targets in Diabetic Retinopathy

Khan, Z. A., & Chakrabarti, S. (2007) · Journal of Diabetes Research · doi:10.1155/2007/31867 · Cited by 95

LR-90 a new advanced glycation endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats

Scott, S., Loera, S., Tessler, C., Chu, P., Weiss, L. M., Hardy, J. W., Rahbar, S., & Figarola, J. L. (2003) · Diabetologia · doi:10.1007/s00125-003-1162-0 · Cited by 96

Conventional Antibody against N�-(Carboxymethyl)Lysine (CML) Shows Cross-Reaction to N�-(Carboxyethyl)Lysine (CEL): Immunochemical Quantification of CML with a Specific Antibody

Koito, W. (2004) · The Journal of Biochemistry · doi:10.1093/jb/mvh193 · Cited by 93

Advanced Glycation End Product Precursors Impair Epidermal Growth Factor Receptor Signaling

Portero‐Otín, M., Pamplona, R., Bellmunt, M. J., Ruiz, M. C., Prat, J., Salvayre, R., & Nègre‐Salvayre, A. (2002) · Diabetes · doi:10.2337/diabetes.51.5.1535 · Cited by 92

Dietary consumption of advanced glycation end products and pancreatic cancer in the prospective NIH-AARP Diet and Health Study

Jiao, L., Stolzenberg‐Solomon, R. Z., Zimmerman, T. P., Duan, Z., Chen, L., Kahle, L., Risch, A., Subar, A. F., Cross, A. J., Hollenbeck, A. R., et al. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.098061 · Cited by 91

Detection of α-Dicarbonyl Compounds in Maillard Reaction Systems and in Vivo

Glomb, M. A., & Tschirnich, R. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010148h · Cited by 90

Radical-Assisted Melanoidin Formation during Thermal Processing of Foods as well as under Physiological Conditions

Hofmann, T., Bors, W., & Stettmaier, K. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980627p · Cited by 87

Glyceraldehyde-derived advanced glycation end products in Alzheimer?s disease

Choei, H., Sasaki, N., Takeuchi, M., Yoshida, T., Ukai, W., Yamagishi, S., Kikuchi, S., & Saito, T. (2004) · Acta Neuropathologica · doi:10.1007/s00401-004-0871-x · Cited by 86

Carnosine and advanced glycation end products: a systematic review

Ghodsi, R., & Kheirouri, S. (2018) · Amino Acids · doi:10.1007/s00726-018-2592-9 · Cited by 89

Protein Aging by Carboxymethylation of Lysines Generates Sites for Divalent Metal and Redox Active Copper Binding: Relevance to Diseases of Glycoxidative Stress

Saxena, A. K., Saxena, P., Wu, X., Obrenovich, M. E., Weiss, M. F., & Monnier, V. M. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0898 · Cited by 83

Kinetics of Nonenzymatic Glycation of Ribonuclease A Leading to Advanced Glycation End Products. Paradoxical Inhibition by Ribose Leads to Facile Isolation of Protein Intermediate for Rapid Post-Amadori Studies

Khalifah, R. G., Todd, P., Booth, A. A., Yang, S. X., Mott, J. D., & Hudson, B. G. (1996) · Biochemistry · doi:10.1021/bi9525942 · Cited by 83

Toward better dialysis compatibility: Advances in the biochemistry and pathophysiology of the peritoneal membranes

Miyata, T., Devuyst, O., Kurokawa, K., & de Strihou, C. V. Y. (2002) · Kidney International · doi:10.1046/j.1523-1755.2002.00135.x · Cited by 83

Advanced glycation and glycoxidation end products in bone

Wang, B., & Vashishth, D. (2023) · Bone · doi:10.1016/j.bone.2023.116880 · Cited by 86

Comprehensive Analysis of Maillard Protein Modifications in Human Lenses: Effect of Age and Cataract

Smuda, M., Henning, C., Raghavan, C. T., Johar, K., Vasavada, A. R., Nagaraj, R. H., & Glomb, M. A. (2015) · Biochemistry · doi:10.1021/bi5013194 · Cited by 82

Proteomic Analysis of the Site Specificity of Glycation and Carboxymethylation of Ribonuclease

Brock, J. W. C., Hinton, D. J. S., Cotham, W. E., Metz, T., Thorpe, S. R., Baynes, J., & Ames, J. M. (2003) · Journal of Proteome Research · doi:10.1021/pr0340173 · Cited by 82

Taurine and oxidative stress in retinal health and disease

Castelli, V., Paladini, A., d’Angelo, M., Allegretti, M., Mantelli, F., Brandolini, L., Cocchiaro, P., Cimini, A., & Varrassi, G. (2021) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13610 · Cited by 84

Regulation of advanced glycation end product (AGE)-receptor (RAGE) system by PPAR-gamma agonists and its implication in cardiovascular disease

Yamagishi, S., Nakamura, K., & Matsui, T. (2009) · Pharmacological Research · doi:10.1016/j.phrs.2009.01.006 · Cited by 81

2‐Isopropylidenehydrazono‐4‐oxo‐thiazolidin‐5‐ylacetanilide (OPB‐9195) treatment inhibits the development of intimal thickening after balloon injury of rat carotid artery: role of glycoxidation and lipoxidation reactions in vascular tissue damage

Miyata, T., Ishikawa, S., Asahi, K., Inagi, R., Suzuki, D., Horie, K., Tatsumi, K., & Kurokawa, K. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00122-2 · Cited by 80

Propagation of protein glycation damage involves modification of tryptophan residues via reactive oxygen species: inhibition by pyridoxamine

Chetyrkin, S. V., Mathis, M., Ham, A. L., Hachey, D. L., Hudson, B. G., & Voziyan, P. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.09.016 · Cited by 79

Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.

Farboud, B., Aotaki-Keen, A. E., Miyata, T., Hjelmeland, L. M., & Handa, J. T. (1999) · PubMed · Cited by 80

Endothelins in chronic diabetic complications

Khan, Z. A., & Chakrabarti, S. (2003) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y03-053 · Cited by 79

Elevation of Nε-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis

Yagmur, E., Tacke, F., Weiß, C., Lahme, B., Manns, M. P., Kiefer, P., Trautwein, C., & Gressner, A. M. (2005) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2005.07.016 · Cited by 78

Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

Brown, B. E., Dean, R. T., & Davies, M. J. (2005) · Diabetologia · doi:10.1007/s00125-004-1648-4 · Cited by 78

Green Tea Extract Suppresses the Age-Related Increase in Collagen Crosslinking and Fluorescent Products in C57BL/6 Mice

Rutter, Sell, Fraser, Obrenovich, Zito, Starke-Reed, & Monnier (2003) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831.73.6.453 · Cited by 76

Antiglycation and antioxidant activities of mogroside extract from Siraitia grosvenorii (Swingle) fruits

Liu, H., Wang, C., Qi, X., Zou, J., & Sun, Z. (2018) · Journal of Food Science and Technology · doi:10.1007/s13197-018-3105-2 · Cited by 76

Contribution of Phosphate Intrinsic Binding Energy to the Enzymatic Rate Acceleration for Triosephosphate Isomerase

Amyes, T. L., O’Donoghue, A. C., & Richard, J. P. (2001) · Journal of the American Chemical Society · doi:10.1021/ja016754a · Cited by 76

Metabolization of the Advanced Glycation End Product N-ε-Carboxymethyllysine (CML) by Different Probiotic E. coli Strains

Hellwig, M., Auerbach, C., Müller, N., Samuel, P., Kammann, S., Beer, F., Gunzer, F., & Henle, T. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b06748 · Cited by 76

In-depth understanding of molecular mechanisms of aldehyde toxicity to engineer robust Saccharomyces cerevisiae

Jayakody, L. N., & Jin, Y. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11213-1 · Cited by 75

Protective Effect of (-)-Epigallocatechin Gallate against Advanced Glycation Endproducts-Induced Injury in Neuronal Cells

Lee, S., & Lee, K. (2007) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.30.1369 · Cited by 75

Modification and Inactivation of Human Cu,Zn-Superoxide Dismutase by Methylglyoxal

Kang, J. H. (2003) · Molecules and Cells · doi:10.1016/s1016-8478(23)13727-7 · Cited by 75

Glycation and glycoxidation of low‐density lipoproteins by glucose and low‐molecular mass aldehydes

Knott, H. M., Brown, B. E., Davies, M. J., & Dean, R. T. (2003) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2002.03017.x · Cited by 75

Studies of renal injury III: Lipid-induced nephropathy in type II diabetes

Dominguez, J. H., Tang, N., Xu, W., Evan, A. P., Siakotos, A. N., Agarwal, R., Walsh, J., Deeg, M. A., Pratt, J. H., March, K. L., et al. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00814.x · Cited by 75

Advanced glycation end products (AGEs) and cardiovascular dysfunction: focus on high molecular weight AGEs

Deluyker, D., Evens, L., & Bito, V. (2017) · Amino Acids · doi:10.1007/s00726-017-2464-8 · Cited by 74

Unusual susceptibility of heme proteins to damage by glucose during non-enzymatic glycation

Cussimanio, B. L., Booth, A. A., Todd, P., Hudson, B. G., & Khalifah, R. G. (2003) · Biophysical Chemistry · doi:10.1016/s0301-4622(03)00100-5 · Cited by 74

Structure of advanced Maillard reaction products and their pathological role

Monnier, V. M., Nagaraj, R. H., Portero‐Otín, M., Glomb, M. A., Elgawish, A.-H., Sell, D. R., & Friedlander, M. A. (1996) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/11.supp5.20 · Cited by 74

AGEs in human lens capsule promote the TGFβ2‐mediated EMT of lens epithelial cells: implications for age‐associated fibrosis

Raghavan, C. T., Smuda, M., Smith, A. J. O., Howell, S. J., Smith, D. G., Singh, A., Gupta, P., Glomb, M. A., Wormstone, I. M., & Nagaraj, R. H. (2016) · Aging Cell · doi:10.1111/acel.12450 · Cited by 74

Production of Nε-(Carboxymethyl)Lysine Is Impaired in Mice Deficient in NADPH Oxidase

Anderson, M. M., & Heinecke, J. W. (2003) · Diabetes · doi:10.2337/diabetes.52.8.2137 · Cited by 73

Aldose reductase: a window to the treatment of diabetic complications?

Crabbe, M. J. C., & Goode, D. (1998) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(97)00013-x · Cited by 73

Impact of Advanced Glycation End products (AGEs) and its receptor (RAGE) on cancer metabolic signaling pathways and its progression

Muthyalaiah, Y. S., Jonnalagadda, B., John, C. M., & Arockiasamy, S. (2021) · Glycoconjugate Journal · doi:10.1007/s10719-021-10031-x · Cited by 75

A glycolytic metabolite bypasses “two-hit” tumor suppression by BRCA2

Kong, L. R., Gupta, K., Wu, A., Perera, D., Iványi-Nagy, R., Ahmed, S. M., Tan, T. Z., Tan, S. L.-W., Fuddin, A., Sundaramoorthy, E., et al. (2024) · Cell · doi:10.1016/j.cell.2024.03.006 · Cited by 74

Induction of Apoptosis by Glyoxal in Human Embryonic Lung Epithelial Cell Line L132

Kasper, M. E., Roehlecke, C., Witt, M., Fehrenbach, H., Hofer, A., Miyata, T., Weigert, C., Funk, R. H. W., & Schleicher, E. D. (2000) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.23.4.4117 · Cited by 72

Potential Clinical Utility of Advanced Glycation End Product Cross-Link Breakers in Age- and Diabetes-Associated Disorders

Yamagishi, S. (2012) · Rejuvenation Research · doi:10.1089/rej.2012.1335 · Cited by 72

Role of Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Cancer Risk

Yamagishi, S., Matsui, T., & Fukami, K. (2014) · Rejuvenation Research · doi:10.1089/rej.2014.1625 · Cited by 72

Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis

Fan, X., Sell, D. R., Zhang, J., Nemet, I., Theves, M., Lu, J., Strauch, C., Halushka, M. K., & Monnier, V. M. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.06.003 · Cited by 70

Cross-linking of proteins by maillard processes—characterization and detection of a lysine-arginine cross-link derived from d-glucose

Lederer, M. O., & Bühler, H. (1999) · Bioorganic & Medicinal Chemistry · doi:10.1016/s0968-0896(99)00040-1 · Cited by 69

Prediction of diabetic retinopathy: role of oxidative stress and relevance of apoptotic biomarkers

Al‐Shabrawey, M., & Smith, S. B. (2010) · The EPMA Journal · doi:10.1007/s13167-010-0002-9 · Cited by 69

Oxidative deamination of lysine residue in plasma protein of diabetic rats

Akagawa, M., Sasaki, T., & Suyama, K. (2002) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2002.03243.x · Cited by 67

Transition metal-catalyzed oxidation of ascorbate in human cataract extracts: possible role of advanced glycation end products.

Saxena, P. N., Saxena, A. K., Cui, X.-L., Obrenovich, M. E., Gudipaty, K., & Monnier, V. M. (2000) · PubMed · Cited by 67

Glycer-AGEs-RAGE signaling enhances the angiogenic potential of hepatocellular carcinoma by upregulating VEGF expression

Takino, J. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i15.1781 · Cited by 64

In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques

Imanaga, Y., Sakata, N., Takebayashi, S., Matsunaga, A., Sasaki, J., Arakawa, K., Nagai, R., Horiuchi, S., Itabe, H., & Takano, T. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00396-2 · Cited by 65

Site specificity of glycation and carboxymethylation of bovine serum albumin by fructose

Hinton, D. J. S., & Ames, J. M. (2006) · Amino Acids · doi:10.1007/s00726-006-0269-2 · Cited by 65

Formation of Lipid Oxidation and Isomerization Products during Processing of Nuts and Sesame Seeds

Yaacoub, R., Saliba, R., Nsouli, B., Khalaf, G., & Birlouez‐Aragon, I. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf800808d · Cited by 65

Inhibition of advanced glycation end-product formation on eye lens protein by rutin

Muthenna, P., Akileshwari, C., Saraswat, M., & Reddy, G. B. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511004077 · Cited by 65

Advanced glycation end products in uremia

Henle, T., & Miyata, T. (2003) · Advances in Renal Replacement Therapy · doi:10.1053/j.arrt.2003.08.006 · Cited by 65

Glyoxylate, a New Marker Metabolite of Type 2 Diabetes

Nikiforova, V. J., Giesbertz, P., Wiemer, J. C., Bethan, B., Looser, R., Liebenberg, V., Ruíz, P., Daniel, H., & Rein, D. (2014) · Journal of Diabetes Research · doi:10.1155/2014/685204 · Cited by 65

Carbonyl compounds cross-link cellular proteins and activate protein-tyrosine kinase p60c-Src

Akhand, A. A., Kato, M., Suzuki, H., Liu, W., Du, J., Hamaguchi, M., Miyata, T., Kurokawa, K., & Nakashima, I. (1999) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(19990101)72:1 · Cited by 63

Chemical modification of muscle protein in diabetes

Alt, N., Carson, J. A., Alderson, N. L., Wang, Y., Nagai, R., Henle, T., Thorpe, S. R., & Baynes, J. (2004) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2004.03.012 · Cited by 62

A correlation between oxidative stress and diabetic retinopathy: An updated review

Hussain, A., Ashique, S., Afzal, O., Altamimi, M. A., Malik, A., Kumar, S., Garg, A., Sharma, N., Farid, A., Khan, T., et al. (2023) · Experimental Eye Research · doi:10.1016/j.exer.2023.109650 · Cited by 70

Comprehensive Analysis of Nonenzymatic Post-Translational β-Lactoglobulin Modifications in Processed Milk by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry

Meltretter, J., Wüst, J., & Pischetsrieder, M. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf401549j · Cited by 67

Molecular Basis of Maillard Amide-Advanced Glycation End Product (AGE) Formation in Vivo

Henning, C., Smuda, M., Girndt, M., Ulrich, C., & Glomb, M. A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.282442 · Cited by 60

Towards Newer Molecular Targets for Chronic Diabetic Complications

Khan, Z. A., Farhangkhoee, H., & Chakrabarti, S. (2005) · Current Vascular Pharmacology · doi:10.2174/157016106775203081 · Cited by 60

Reactive Carbonyls Are a Major Th2-Inducing Damage-Associated Molecular Pattern Generated by Oxidative Stress

Moghaddam, A. E., Gartlan, K. H., Kong, L., & Sattentau, Q. J. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1003906 · Cited by 60

Conversion of Amadori Products of the Maillard Reaction to Nε-(carboxymethyl)lysine by Short-Term Heating: Possible Detection of Artifacts by Immunohistochemistry

Hayashi, C. M., Nagai, R., Miyazaki, K., Hayase, F., Araki, T., Ono, T., & Horiuchi, S. (2002) · Laboratory Investigation · doi:10.1097/01.lab.0000018826.59648.07 · Cited by 59

Comprehensive Analyses of Carbohydrates, 1,2-Dicarbonyl Compounds, and Advanced Glycation End Products in Industrial Bread Making

Jost, T., Henning, C., Heymann, T., & Glomb, M. A. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c07614 · Cited by 58

Differences in kinetics and dynamics of endogenous versus exogenous advanced glycation end products (AGEs) and their precursors

van Dongen, K. C. W., Kappetein, L., Estruch, I. M., Belzer, C., Beekmann, K., & Rietjens, I. M. C. M. (2022) · Food and Chemical Toxicology · doi:10.1016/j.fct.2022.112987 · Cited by 63

Degradation of glycated bovine serum albumin in microglial cells

Stolzing, A., Widmer, R., Jung, T., Voß, P., & Grune, T. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.10.061 · Cited by 61

Liquid Chromatographic Determination of Glyoxal and Methylglyoxal from Serum of Diabetic Patients using Meso‐Stilbenediamine as Derivatizing Reagent

Khuhawar, M. Y., Kandhro, A. J., & Khand, F. (2006) · Analytical Letters · doi:10.1080/00032710600754093 · Cited by 58

Author index

Knott, H. M., Brown, B. E., Davies, M. J., & Dean, R. T. (2003) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2003.03742.x · Cited by 58

Modification of Amino Acid Residues in Carious Dentin Matrix

Kleter, G. A., Damen, J. J. M., Buijs, M. J., & ten Cate, J. M. (1998) · Journal of Dental Research · doi:10.1177/00220345980770030801 · Cited by 57

Protein and Low Molecular Mass Thiols as Targets and Inhibitors of Glycation Reactions

Zeng, J., & Davies, M. J. (2006) · Chemical Research in Toxicology · doi:10.1021/tx0602158 · Cited by 57

Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products

Machado‐Lima, A., Pinto, R. S., Moyses, Z. P., Nakandakare, E. R., Quintão, E. C. R., & Passarelli, M. (2005) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.09.016 · Cited by 56

The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity

Takino, J.-I., Kobayashi, Y., & Takeuchi, M. (2010) · Journal of Gastroenterology · doi:10.1007/s00535-009-0193-9 · Cited by 56

The Role of Nonenzymatic Glycation and Carbonyls in Collagen Cross-Linking for the Treatment of Keratoconus

Brummer, G., Littlechild, S. L., McCall, S., Zhang, Y., & Conrad, G. W. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-7585 · Cited by 56

LC-MS/MS analysis of carboxymethylated and carboxyethylated phosphatidylethanolamines in human erythrocytes and blood plasma

Shoji, N., Nakagawa, K., Asai, A., Fujita, I., Hashiura, A., Nakajima, Y., Oikawa, S., & Miyazawa, T. (2010) · Journal of Lipid Research · doi:10.1194/jlr.d004564 · Cited by 56

Identification of Nω-Carboxymethylarginine, a New Advanced Glycation Endproduct in Serum Proteins of Diabetic Patients: Possibility of a New Marker of Aging and Diabetes

Odani, H., Iijima, K., Nakata, M., Miyata, S., Kusunoki, H., Yasuda, Y., Hiki, Y., Irie, S., Maeda, K., & Fujimoto, D. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5322 · Cited by 56

Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

Shibata, N., Nagai, R., Miyata, S., Jono, T., Horiuchi, S., Hirano, A., Kato, S., Sasaki, S., Asayama, K., & Kobayashi, M. (2000) · Acta Neuropathologica · doi:10.1007/s004019900173 · Cited by 56

Accelerated Formation of Nϵ-(carboxymethyl) Lysine, an Advanced Glycation End Product, by Glyoxal and 3-Deoxyglucosone in Cultured Rat Sensory Neurons

Niwa, H., Takeda, A., Wakai, M., Miyata, T., Yasuda, Y., Mitsuma, T., Kurokawa, K., & Sobue, G. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8899 · Cited by 56

Melanoidins from Coffee, Cocoa, and Bread Are Able to Scavenge α-Dicarbonyl Compounds under Simulated Physiological Conditions

Zhang, H., Zhang, H., Troise, A. D., & Fogliano, V. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b03744 · Cited by 59

Early Glycation Products Produce Pentosidine Cross-links on Native Proteins

Chellan, P., & Nagaraj, R. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008626200 · Cited by 57

Lactose hydrolysis and protein fortification pose an increased risk for the formation of Maillard reaction products in UHT treated milk products

Aktağ, I. G., Hamzalıoğlu, A., & Gökmen, V. (2019) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2019.103308 · Cited by 54

A quantitative model of the generation of N∊-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose

Ferreira, A. E. N., Freire, A. P., & Voit, E. O. (2003) · Biochemical Journal · doi:10.1042/bj20030496 · Cited by 54

Protein Modifications by Glyoxal and Methylglyoxal During the Maillard Reaction of Higher Sugars

Glomb, M. A., & Nagaraj, R. H. (2005) · The Maillard Reaction in Foods and Medicine · doi:10.1533/9781845698447.7.250 · Cited by 1

Novel Amidine Protein Cross-Links Formed by the Reaction of Glyoxal with Lysine

Eggen, M. D., & Glomb, M. A. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c02792 · Cited by 23

A quantitative model of the generation of N∊-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose

Ferreira, A. E. N., Freire, A. P., & Voit, E. O. (2003) · Biochemical Journal · doi:10.1042/bj20030496 · Cited by 54

Amides Are Novel Protein Modifications Formed by Physiological Sugars

Glomb, M. A., & Pfahler, C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103557200 · Cited by 144

Pathways of Formation of Glycoxidation Products during Glycation of Collagen

Wells-Knecht, M. C., Thorpe, S. R., & Baynes, J. (1995) · Biochemistry · doi:10.1021/bi00046a020 · Cited by 155