Purification and Properties of HuD, a Neuronal RNA-binding Protein

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Conserved Structures and Diversity of Functions of RNA-Binding Proteins

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RNA recognition: towards identifying determinants of specificity

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Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein

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The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.Preprint

Shyu, A. B., Greenberg, M. E., & Belasco, J. G. (1989) · Genes & Development · doi:10.1101/gad.3.1.60 · Cited by 606 · see citing works

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

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HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal

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The Nonamer UUAUUUAUU Is the Key AU-Rich Sequence Motif That Mediates mRNA Degradation

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Purification, Characterization, and cDNA Cloning of an AU-Rich Element RNA-Binding Protein, AUF1

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Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.Preprint

Shyu, A. B., Belasco, J. G., & Greenberg, M. E. (1991) · Genes & Development · doi:10.1101/gad.5.2.221 · Cited by 523 · see citing works

Identification of an AUUUA-Specific Messenger RNA Binding Protein

Malter, J. S. (1989) · Science · doi:10.1126/science.2814487 · Cited by 497 · see citing works

Hu neuronal proteins are expressed in proliferating neurogenic cells

Marusich, M. F., Furneaux, H. M., Henion, P. D., & Weston, J. A. (1994) · Journal of Neurobiology · doi:10.1002/neu.480250206 · Cited by 485 · see citing works

mRNA Polyadenylate-Binding Protein: Gene Isolation and Sequencing and Identification of a Ribonucleoprotein Consensus Sequence

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Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

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A conserved family of elav-like genes in vertebrates.

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Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

Scherly, D., Boelens, W. C., VENROOIJ, W. J. V., Dathan, N. A., Hamm, J., & Mattaj, I. W. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08601.x · Cited by 309 · see citing works

The elav Gene Product of Drosophila , Required in Neurons, Has Three RNP Consensus Motifs

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mRNA Decay Mediated by Two Distinct AU-Rich Elements from c- fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation

Chen, C. A., Xu, N., & Shyu, A. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.10.5777 · Cited by 275 · see citing works

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

Vakalopoulou, E., Schaack, J. B., & Shenk, T. E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3355 · Cited by 266 · see citing works

Selective Degradation of Early-Response-Gene mRNAs: Functional Analyses of Sequence Features of the AU-Rich Elements

Chen, C. A., & Shyu, A. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8471-8482.1994 · Cited by 252 · see citing works

Sequence-specific interaction of R17 coat protein with its ribonucleic acid binding site

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The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

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Mutant Alleles at the Locus elav in Drosophila melanogaster lead to Nervous System Defects. A Developmental-Genetic Analysis

Campos, A. R., And, D. G., & White, K. (1985) · Journal of Neurogenetics · doi:10.3109/01677068509100150 · Cited by 210 · see citing works

Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain

Barami, K., Iversen, K., Furneaux, H., & Goldman, S. A. (1995) · Journal of Neurobiology · doi:10.1002/neu.480280108 · Cited by 209 · see citing works

Interplay of two functionally and structurally distinct domains of the c- fos AU-rich element specifies its mRNA-destabilizing function

Chen, C.-Y. A., Chen, T.-M., & Shyu, A. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.1.416-426.1994 · Cited by 185 · see citing works

A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

Malter, J. S., & Hong, Y. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)49969-3 · Cited by 181 · see citing works

Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements.

Chen, C. Y., & Shyu, A. B. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8471 · Cited by 168 · see citing works

Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor

King, P. H., Levine, T., Fremeau, R. T., & Keene, J. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-01943.1994 · Cited by 167 · see citing works

AU RNA-binding factors differ in their binding specificities and affinities.

Bohjanen, P. R., Petryniak, B., June, C. H., Thompson, C. B., & Lindsten, T. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42696-8 · Cited by 156 · see citing works

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.

Gao, F., Carson, C. C., Levine, T., & Keene, J. D. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.11207 · Cited by 156 · see citing works

AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity.

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Paraneoplastic Encephalomyelitis Antigens Bind to the AU-rich Elements of mRNA

Liu, J., Dalmau, J., Szabo, A., Rosenfeld, M., Huber, J., & Furneaux, H. (1995) · Neurology · doi:10.1212/wnl.45.3.544 · Cited by 122 · see citing works

Mechanisms regulating the level of IL-2 mRNA in T lymphocytes.

Shaw, J., Meerovitch, K., Bleackley, R. C., & Paetkau, V. H. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.140.7.2243 · Cited by 114 · see citing works

A region of the Drosophila genome necessary for CNS development

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The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific in both flies and humans

Kim, Y., & Baker, B. S. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-03-01045.1993 · Cited by 87 · see citing works

AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm

Katz, D. A., Theodorakis, N. D., Cleveland, D. W., & Lindsten, T. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.2.238 · Cited by 78 · see citing works

The M(r) 35,000 beta-adrenergic receptor mRNA-binding protein induced by agonists requires both an AUUUA pentamer and U-rich domains for RNA recognition.

Huang, L., Tholanikunnel, B. G., Vakalopoulou, E., & Malbon, C. C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74456-1 · Cited by 60 · see citing works

Isolation and characterization of two fractions from HeLa cells required for mRNA splicing in vitro.

Furneaux, H., Perkins, K. K., Freyer, G. A., et al. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.13.4351 · Cited by 52 · see citing works

Developmental and Physiological Analysis of a Conditional Mutation Affecting Photoreceptor and Optic Lobe Development in Drosophila melanogaster

Homyk, T., Isono, K., & Pak, W. L. (1985) · Journal of Neurogenetics · doi:10.3109/01677068509102326 · Cited by 46 · see citing works

Review : The Immediate-Early Gene Response and Neuronal Death and Regeneration

Morgan, J. I., & Curran, T. (1995) · The Neuroscientist · doi:10.1177/107385849500100203 · Cited by 33 · see citing works

Tissue-Specific Expression of the Gene Encoding a Mouse RNA Binding Protein Homologous to Human HuD Antigen

Abe, R. (1994) · DNA Research · doi:10.1093/dnares/1.4.175 · Cited by 30 · see citing works

Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family

Perron, M., Théodore, L., & Wegnez, M. R. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(95)00368-1 · Cited by 18 · see citing works

Assemblage of the prespliceosome complex with separated fractions isolated from HeLa cells.

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Diverse molecular functions of Hu proteins

Hinman, M. N., & Lou, H. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8252-6 · Cited by 587 · see citing works

The neurogenetics of alternative splicing

Vuong, C. K., Black, D. L., & Zheng, S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.27 · Cited by 340 · see citing works

Defining a neuron: neuronal ELAV proteins

Pascale, A., Amadio, M., & Quattrone, A. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7017-y · Cited by 158 · see citing works

Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction

Bronicki, L. M., & Jasmin, B. J. (2013) · RNA · doi:10.1261/rna.039164.113 · Cited by 126 · see citing works

Post-Transcriptional Regulation of the GAP-43 Gene by Specific Sequences in the 3′ Untranslated Region of the mRNA

Tsai, K.-C., Cansino, V. V., Kohn, D. T., Neve, R. L., & Perrone-Bizzozero, N. I. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-06-01950.1997 · Cited by 66 · see citing works

Evidence for 3′ Untranslated Region-Dependent Autoregulation of the Drosophila Gene Encoding the Neuronal Nuclear RNA-Binding Protein ELAV

Samson, M.-L. (1998) · Genetics · doi:10.1093/genetics/150.2.723 · Cited by 51 · see citing works

Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members

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Importance of RNA isolation methods for analysis of exosomal RNA: Evaluation of different methods

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Polyadenylic acid on poliovirus RNA. II. poly(A) on intracellular RNAs

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The Effect of Formaldehyde Fixation on RNA

Evers, D. L., Fowler, C. B., Cunningham, B. R., Mason, J. T., & O’Leary, T. J. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2011.01.010 · Cited by 127 · see citing works

Paraffin Embedding Contributes to RNA Aggregation, Reduced RNA Yield, and Low RNA Quality

Evers, D. L., He, J., Kim, Y. H., et al. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2011.06.007 · Cited by 64 · see citing works

RNA extraction for RNA sequencing of archival renal tissues

Landolt, L. Z., Marti, H., Beisland, C., Flatberg, A., & Eikrem, Ø. (2016) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365513.2016.1177660 · Cited by 59 · see citing works