The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Tissue-specific Ablation of the GLUT4 Glucose Transporter or the Insulin Receptor Challenges Assumptions about Insulin Action and Glucose Homeostasis
Open accessAbstract
The prevalence of type 2 diabetes mellitus is growing worldwide. Most forms of type 2 diabetes are polygenic with complex inheritance patterns strongly influenced by environmental factors. The specific gene defects are unknown, but they affect both insulin action and insulin secretion. Glucose homeostasis is maintained by the fine orchestration of insulin secretion and insulin action to promote glucose transport into muscle and adipocytes and to inhibit hepatic glucose output. Resistance to these effects of insulin is a classic pathogenic feature of obesity and type 2 diabetes.
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Cites
Insulin signalling and the regulation of glucose and lipid metabolism
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Self-citationGlucose Transporters and Insulin Action — Implications for Insulin Resistance and Diabetes Mellitus
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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes
Fernández, A. M., Kim, J. K., Yakar, S., Dupont, J., Hernandez-Sanchez, C., Castle, A. L., Filmore, J., Shulman, G. I., & Le Roith, D. (2001) · Genes & Development · doi:10.1101/gad.908001 · Cited by 369
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Self-citationGlucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4
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Cited by
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
Yang, Q., Graham, T. E., Mody, N., Preitner, F., Peroni, O. D., Zabolotny, J. M., Kotani, K., Quadro, L., & Kahn, B. B. (2005) · Nature · doi:10.1038/nature03711 · Cited by 2,086
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Glucocorticoids, metabolism and metabolic diseases
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Current views on type 2 diabetes
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Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities
Opazo-Ríos, L., Mas, S., Marín-Royo, G., Mezzano, S., Gómez-Guerrero, C., Moreno, J. A., & Egido, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072632 · Cited by 363
Metadata
- Authors
- Minokoshi, Y., Kahn, C. R., & Kahn, B. B.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2003-09
- Volume
- 278
- Issue
- 36
- Pages
- 33609-33612
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2062244719
- Cited by
- 220
- References
- 9
- FWCI
- 4.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Minokoshi, Y., Kahn, C. R., & Kahn, B. B. (2003). Tissue-specific Ablation of the GLUT4 Glucose Transporter or the Insulin Receptor Challenges Assumptions about Insulin Action and Glucose Homeostasis. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.r300019200
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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