Expanded Roles for Chk1 in Genome Maintenance

Chromatin modifications and their function

Kouzarides, T. (2007) · Cell · doi:10.1016/j.cell.2007.02.005 · Cited by 10,883 · see citing works

Chk1 is an essential kinase that is regulated by Atr and required for the G ₂ /M DNA damage checkpoint

Liu, Q., Guntuku, S., Cui, X.-S., Matsuoka, S., Cortez, D., Tamai, K., Luo, G., Carattini-Rivera, S., DeMayo, F., Bradley, A., et al. (2000) · Genes & Development · doi:10.1101/gad.14.12.1448 · Cited by 1,625 · see citing works

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H., & Elledge, S. J. (1997) · Science · doi:10.1126/science.277.5331.1497 · Cited by 1,320 · see citing works

Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

Garcia-Higuera, I., Taniguchi, T., Ganesan, S., Meyn, M. S., Timmers, C., Hejna, J., Grompe, M., & D'Andrea, A. D. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00173-3 · Cited by 1,198 · see citing works

E2F integrates cell cycle progression with DNA repair, replication, and G ₂ /M checkpoints

Ren, B., Cam, H., Takahashi, Y., Volkert, T., Terragni, J., Young, R. A., & Dynlacht, B. D. (2002) · Genes & Development · doi:10.1101/gad.949802 · Cited by 1,125 · see citing works

ATR and ATRIP: Partners in Checkpoint Signaling

Cortez, D., Guntuku, S., Qin, J., & Elledge, S. J. (2001) · Science · doi:10.1126/science.1065521 · Cited by 985 · see citing works

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systemsPreprint

Liu, M., Pereira, F. A., Price, S. D., Chu, M.-J., Shope, C. D., Himes, D., Eatock, R. A., Brownell, W. E., Lysakowski, A., & Tsai, M. (2000) · Genes & Development · doi:10.1101/gad.840500 · Cited by 625 · see citing works

Active cyclin B1–Cdk1 first appears on centrosomes in prophase

Jackman, M. R., Lindon, C., Nigg, E. A., & Pines, J. (2003) · Nature Cell Biology · doi:10.1038/ncb918 · Cited by 614 · see citing works

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A

Sørensen, C. S., Syljuåsen, R. G., Falck, J., Schroeder, T., Rönnstrand, L., Khanna, K. K., Zhou, B.-B., Bártek, J., & Lukas, J. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00048-5 · Cited by 560 · see citing works

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

Furnari, B. A., Rhind, N., & Russell, P. R. (1997) · Science · doi:10.1126/science.277.5331.1495 · Cited by 542 · see citing works

Aberrant cell cycle checkpoint function and early embryonic death in Chk1−/− micePreprint

Takai, H., Tominaga, K., Motoyama, N., Minamishima, Y. A., Nagahama, H., Tsukiyama, T., Ikeda, K., Nakayama, K., Nakanishi, M., & Nakayama, K. (2000) · Genes & Development · doi:10.1101/gad.14.12.1439 · Cited by 478 · see citing works

The DNA damage-dependent intra–S phase checkpoint is regulated by parallel pathways

Falck, J., Petrini, J. H. J., Williams, B. R., Lukas, J., & Bartek, J. (2002) · Nature Genetics · doi:10.1038/ng845 · Cited by 392 · see citing works

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

Zhou, B. S., & Bártek, J. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1296 · Cited by 390 · see citing works

Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase

Krämer, A., Mailand, N., Lukas, C., Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bártek, J., & Lukas, J. (2004) · Nature Cell Biology · doi:10.1038/ncb1165 · Cited by 338 · see citing works

Replication Checkpoint Enforced by Kinases Cds1 and Chk1

Boddy, M. N., Furnari, B., Mondesert, O., & Russell, P. (1998) · Science · doi:10.1126/science.280.5365.909 · Cited by 316 · see citing works

Loss of centrosome integrity induces p38—p53—p21-dependent G1—S arrest

Mikule, K. W., Delaval, B., Kaldis, P., Jurcyzk, A., Hergert, P. J., & Doxsey, S. (2006) · Nature Cell Biology · doi:10.1038/ncb1529 · Cited by 306 · see citing works

Chk1 Is a Histone H3 Threonine 11 Kinase that Regulates DNA Damage-Induced Transcriptional Repression

Shimada, M., Niida, H., Zineldeen, D. H., Tagami, H., Tanaka, M., Saito, H., & Nakanishi, M. (2008) · Cell · doi:10.1016/j.cell.2007.12.013 · Cited by 255 · see citing works

Chk1 is haploinsufficient for multiple functions critical to tumor suppression

Lam, M. H., Liu, Q., Elledge, S. J., & Rosen, J. M. (2004) · Cancer Cell · doi:10.1016/j.ccr.2004.06.015 · Cited by 246 · see citing works

ATRIP Binding to Replication Protein A-Single-stranded DNA Promotes ATR–ATRIP Localization but Is Dispensable for Chk1 Phosphorylation

Ball, H. L., Myers, J. S., & Cortez, D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-11-1006 · Cited by 241 · see citing works

The structural determinants of checkpoint activation

MacDougall, C. A., Byun, T. S., Van, C., Yee, M.-C., & Cimprich, K. A. (2007) · Genes & Development · doi:10.1101/gad.1522607 · Cited by 240 · see citing works

Replication Fork Velocities at Adjacent Replication Origins Are Coordinately Modified during DNA Replication in Human Cells

Conti, C., Saccà, B., Herrick, J., Lalou, C., Pommier, Y. G., & Bensimon, A. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-08-0689 · Cited by 236 · see citing works

Chk1 Is Required for Spindle Checkpoint Function

Zachos, G., Black, E. J., Walker, M., Scott, M. T., Vagnarelli, P., Earnshaw, W. C., & Gillespie, D. A. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.01.003 · Cited by 234 · see citing works

The intra-S phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses

Seiler, J. A., Conti, C., Syed, A., Aladjem, M. I., & Pommier, Y. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02278-06 · Cited by 226 · see citing works

Specific Role of Chk1 Phosphorylations in Cell Survival and Checkpoint Activation

Niida, H., Katsuno, Y., Banerjee, B., Hande, M. P., & Nakanishi, M. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01611-06 · Cited by 166 · see citing works

Chk1-Mediated Phosphorylation of FANCE Is Required for the Fanconi Anemia/BRCA Pathway

Wang, X., Kennedy, R. D., Ray, K., Stuckert, P., Ellenberger, T., & D’Andrea, A. D. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02357-06 · Cited by 147 · see citing works

CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers

Bertoni, F., Codegoni, A. M., Furlan, D., Tibiletti, M. G., Capella, C., & Broggini, M. (1999) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(199910)26:2 · Cited by 132 · see citing works

Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability

Bogliolo, M., Lyakhovich, A., Callén, E., Castellà, M., Cappelli, E., Ramı́rez, M. J., Creus, A., Marcos, R., Kalb, R., Neveling, K., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601574 · Cited by 128 · see citing works

Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F‐1 after DNA damage

Inoue, Y., Kitagawa, M., & Taya, Y. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601652 · Cited by 119 · see citing works

DNA Damage-Induced Accumulation of Centrosomal Chk1 Contributes to its Checkpoint Function

Löffler, H., Bochtler, T., Fritz, B., Tews, B., Ho, A. D., Lukas, J., Bártek, J., & Krämer, A. (2007) · Cell Cycle · doi:10.4161/cc.6.20.4810 · Cited by 65 · see citing works

Cdk Inhibition in Human Cells Compromises Chk1 Function and Activates a DNA Damage Response

Maude, S. L., & Enders, G. H. (2005) · Cancer Research · doi:10.1158/0008-5472.780.65.3 · Cited by 58 · see citing works

Radiation down-regulates replication origin activity throughout the S phase in mammalian cells

Larner, J. M., Lee, H., Dijkwel, P. A., Little, R. D., Schildkraut, C. L., & Hamlin, J. L. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.3.803 · Cited by 55 · see citing works

Chk1 frameshift mutation in sporadic and hereditary non-polyposis colorectal cancers with microsatellite instability

Kim, C. J., Lee, J. H., Song, J. W., Cho, Y. G., Kim, S., Nam, S. W., Yoo, N. J., Park, W. S., & Lee, J. Y. (2007) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2007.02.007 · Cited by 32 · see citing works

Regulation of DNA Replication Machinery by Mrc1 in Fission Yeast

Nitani, N., Nakamura, K., Nakagawa, C., Masukata, H., & Nakagawa, T. (2006) · Genetics · doi:10.1534/genetics.106.060053 · Cited by 30 · see citing works

Checkpoint kinase 1 in DNA damage response and cell cycle regulation

Patil, M., Pabla, N., & Dong, Z. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1307-3 · Cited by 317 · see citing works

Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering

Kehe, K., Balszuweit, F., Steinritz, D., & Thiermann, H. (2009) · Toxicology · doi:10.1016/j.tox.2009.01.019 · Cited by 251 · see citing works

Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures

Ropolo, M., Daga, A., Griffero, F., Foresta, M., Casartelli, G., Zunino, A., Poggi, A. D., Cappelli, E., Zona, G., Spaziante, R., et al. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0409 · Cited by 195 · see citing works

DNA Repair and Resistance of Gliomas to Chemotherapy and Radiotherapy

Fròsina, G. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-09-0030 · Cited by 180 · see citing works

Vitamin D inhibits growth of human airway smooth muscle cells through growth factor‐induced phosphorylation of retinoblastoma protein and checkpoint kinase 1

Damera, G., Fogle, H., Lim, P. N., Goncharova, E. A., Zhao, H., Banerjee, A., Tliba, O., Krymskaya, V., & Panettieri, R. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00428.x · Cited by 163 · see citing works

Cisplatin-Induced DNA Damage Activates Replication Checkpoint Signaling Components that Differentially Affect Tumor Cell Survival

Wagner, J. M., & Karnitz, L. M. (2009) · Molecular Pharmacology · doi:10.1124/mol.109.055178 · Cited by 135 · see citing works

Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells

Ferrao, P. T., Bukczynska, E. P., Johnstone, R. W., & McArthur, G. A. (2012) · Oncogene · doi:10.1038/onc.2011.358 · Cited by 133 · see citing works

Crystal Structure of the Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex—Implications for Clamp Loading and Regulation

Dore, A. S., Kilkenny, M. L., Rzechorzek, N. J., & Pearl, L. H. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.04.027 · Cited by 125 · see citing works

DDB1 Targets Chk1 to the Cul4 E3 Ligase Complex in Normal Cycling Cells and in Cells Experiencing Replication Stress

Leung‐Pineda, V., Huh, J., & Piwnica-Worms, H. M. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3382 · Cited by 124 · see citing works

Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor–chemotherapy combinations as an anticancer strategy for solid tumors

Johnson, N., & Shapiro, G. I. (2010) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2010.525221 · Cited by 112 · see citing works

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells

Jansen, J. G., Tsaalbi-Shtylik, A., Hendriks, G., Gali, H., Hendel, A., Johansson, F., Erixon, K., Livneh, Z., Mullenders, L. H. F., Haracska, L., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00071-09 · Cited by 99 · see citing works

Fanconi Anemia

Green, A. M., & Kupfer, G. M. (2009) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2009.01.008 · Cited by 89 · see citing works

p38 Mitogen-Activated Protein Kinase Promotes Cell Survival in Response to DNA Damage but Is Not Required for the G2 DNA Damage Checkpoint in Human Cancer Cells

Phong, M., Horn, R. D. V., Li, S., Tucker‐Kellogg, G., Surana, U., & Ye, X. S. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00949-09 · Cited by 65 · see citing works

The Werner syndrome protein: linking the replication checkpoint response to genome stability

Pichierri, P., Ammazzalorso, F., Bignami, M., & Franchitto, A. (2011) · Aging · doi:10.18632/aging.100293 · Cited by 58 · see citing works

Analysis of Kinase Gene Expression Patterns across 5681 Human Tissue Samples Reveals Functional Genomic Taxonomy of the Kinome

Kilpinen, S. K., Ojala, K., & Kallioniemi, O. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015068 · Cited by 54 · see citing works

BNIP3 is essential for mediating 6-thioguanine- and 5-fluorouracil-induced autophagy following DNA mismatch repair processing

Zeng, X., & Kinsella, T. J. (2010) · Cell Research · doi:10.1038/cr.2010.40 · Cited by 52 · see citing works

ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells

Kim, D.-S., Liu, Y., Oberly, S., Freire, R., & Smolka, M. B. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky625 · Cited by 52 · see citing works

A prescription for ‘stress’ – the role of Hsp90 in genome stability and cellular adaptation

Kaplan, K. B., & Li, R. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.08.006 · Cited by 47 · see citing works

Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2

Pei, X., Dai, Y., Youssefian, L. E., Chen, S., Bodie, W. W., Takabatake, Y., Felthousen, J. G., Almenara, J. A., Kramer, L. B., Dent, P., et al. (2011) · Blood · doi:10.1182/blood-2011-02-339432 · Cited by 46 · see citing works

Checkpoint Kinase Inhibitor AZD7762 Overcomes Cisplatin Resistance in Clear Cell Carcinoma of the Ovary

Itamochi, H., Nishimura, M., Oumi, N., Kato, M., Oishi, T., Shimada, M., Sato, S., Naniwa, J., Sato, S., Kudoh, A., et al. (2013) · International Journal of Gynecological Cancer · doi:10.1097/igc.0000000000000014 · Cited by 44 · see citing works

A dual molecular analogue tuner for dissecting protein function in mammalian cells

Brosh, R., Hrynyk, I., Shen, J., Waghray, A., Zheng, N., & Lemischka, I. R. (2016) · Nature Communications · doi:10.1038/ncomms11742 · Cited by 37 · see citing works

Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio‐resistance in breast cancer

Alsubhi, N. H., Middleton, F. K., Abdel-Fatah, T. M. A., Stephens, P., Doherty, R. E., Arora, A., Moseley, P. M., Chan, S. Y. T., Aleskandarany, M. A., Green, A. R., et al. (2015) · Molecular Oncology · doi:10.1016/j.molonc.2015.09.009 · Cited by 42 · see citing works

Proteome Stability as a Key Factor of Genome Integrity

Gumeni, S., Evangelakou, Z., Gorgoulis, V. G., & Trougakos, I. P. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18102036 · Cited by 41 · see citing works

The Bright and the Dark Sides of DNA Repair in Stem Cells

Fròsina, G. (2010) · BioMed Research International · doi:10.1155/2010/845396 · Cited by 39 · see citing works

Chk1 Haploinsufficiency Results in Anemia and Defective Erythropoiesis

Boles, N. C., Peddibhotla, S., Chen, A. J., Goodell, M. A., & Rosen, J. M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008581 · Cited by 35 · see citing works

Cisplatin associated with LY294002 increases cytotoxicity and induces changes in transcript profiles of glioblastoma cells

Carminati, P. O., Donaires, F. S., Marques, M. M. C., Donadi, E. A., Passos, G. A. S., & Sakamoto‐Hojo, E. T. (2013) · Molecular Biology Reports · doi:10.1007/s11033-013-2849-z · Cited by 33 · see citing works

DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp

Zheng, F., Georgescu, R. E., Yao, N. Y., O’Donnell, M. E., & Li, H. (2022) · Nature Structural & Molecular Biology · doi:10.1038/s41594-022-00742-6 · Cited by 32 · see citing works

A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint

Mondragón, L., Galluzzi, L., Mouhamad, S., Orzáez, M., Vicencio, J. M., Vitale, I., Moure, A., Messeguer, Á., Pérez‐Payá, E., & Kroemer, G. (2009) · APOPTOSIS · doi:10.1007/s10495-008-0310-x · Cited by 31 · see citing works

Associations of ATR and CHEK1 Single Nucleotide Polymorphisms with Breast Cancer

Lin, W., Brock, I. W., Connley, D., Cramp, H. E., Tucker, R. M., Slate, J., Reed, M., Balasubramanian, S. P., Cannon‐Albright, L., Camp, N. J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068578 · Cited by 29 · see citing works

The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA

Kemp, M. G., Lindsey‐Boltz, L. A., & Sancar, A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.235036 · Cited by 30 · see citing works

Module 9: Cell Cycle and Proliferation

Berridge, M. J. (2012) · Cell Signalling Biology · doi:10.1042/csb0001009 · Cited by 28 · see citing works

Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis

Lunardi, A., Varmeh, S., Chen, M., Taulli, R., Guarnerio, J., Ala, U., Seitzer, N., Ishikawa, T., Carver, B. S., Hobbs, R. M., et al. (2015) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-1050 · Cited by 29 · see citing works

Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo

Dai, Y., Chen, S., Shah, R., Pei, X., Wang, L., Almenara, J. A., Kramer, L. B., Dent, P., & Grant, S. (2010) · Blood · doi:10.1182/blood-2010-06-291146 · Cited by 28 · see citing works

E4F1 Is a Master Regulator of CHK1-Mediated Functions

Grote, D., Moison, C., Duhamel, S., Chagraoui, J., Girard, S., Yang, J., Mayotte, N., Coulombe, Y., Masson, J., Brown, G. W., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.03.019 · Cited by 28 · see citing works

Xeroderma Pigmentosa Group A (XPA), Nucleotide Excision Repair and Regulation by ATR in Response to Ultraviolet Irradiation

Musich, P. R., Li, Z., & Zou, Y. (2017) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-319-56017-5_4 · Cited by 23 · see citing works

DNA Adducts of Decarbamoyl Mitomycin C Efficiently Kill Cells without Wild-Type p53 Resulting from Proteasome-Mediated Degradation of Checkpoint Protein 1

Boamah, E. K., Brekman, A., Tomasz, M., Myeku, N., Figueiredo‐Pereira, M. E., Hunter, S. E., Meyer, J. N., Bhosle, R., & Bargonetti, J. (2010) · Chemical Research in Toxicology · doi:10.1021/tx900420k · Cited by 21 · see citing works

A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress

Egger, T., Bordignon, B., & Coquelle, A. (2022) · Scientific Reports · doi:10.1038/s41598-022-09308-4 · Cited by 20 · see citing works

Kv10.1 Regulates Microtubule Dynamics during Mitosis

Movsisyan, N., & Pardo, L. A. (2020) · Cancers · doi:10.3390/cancers12092409 · Cited by 18 · see citing works

Targeting the DNA damage response: PARP inhibitors and new perspectives in the landscape of cancer treatment

Genta, S., Martorana, F., Stathis, A., & Colombo, I. (2021) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2021.103539 · Cited by 18 · see citing works

Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer

Köker, Ş. C., Jahja, E., Shehwana, H., Keşküş, A. G., & Konu, Ö. (2018) · PLoS ONE · doi:10.1371/journal.pone.0208982 · Cited by 18 · see citing works

Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts

Kumar, S., Yoo, H. Y., Kumagai, A., Shevchenko, A., Shevchenko, A., & Dunphy, W. G. (2012) · Cell Cycle · doi:10.4161/cc.11.6.19636 · Cited by 17 · see citing works

Association of genetic variants in ATR-CHEK1 and ATM-CHEK2 pathway genes with risk of colorectal cancer in a Chinese population

Wang, S., Zhang, Y., Chen, M., Wang, Y., Feng, Y., Xu, Z., Zhang, D., Sun, Y., & Fu, Z. (2018) · Oncotarget · doi:10.18632/oncotarget.24299 · Cited by 16 · see citing works

Chking And executing cell division to prevent genomic instability

Peddibhotla, S., & Rosen, J. M. (2009) · Cell Cycle · doi:10.4161/cc.8.15.9169 · Cited by 16 · see citing works

Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit

Palii, S. S., Cui, Y., Innes, C. L., & Paules, R. S. (2013) · Cell Cycle · doi:10.4161/cc.24127 · Cited by 16 · see citing works

Cell-cycle Alterations in Post-mitotic Cells and Cell Death by Mitotic Catastrophe

Lombardi, D., & Lasagni, L. (2016) · InTech eBooks · doi:10.5772/61783 · Cited by 15 · see citing works

Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells

Wilsker, D. F., Chung, J., & Bunz, F. (2012) · Cell Cycle · doi:10.4161/cc.19944 · Cited by 14 · see citing works

Chk1 is required for the metaphase–anaphase transition via regulating the expression and localization of Cdc20 and Mad2

Yang, X., Xu, W. M., Hu, Z., Zhang, Y., & Xu, N. (2014) · Life Sciences · doi:10.1016/j.lfs.2014.04.011 · Cited by 13 · see citing works

Histone XH2AX Is Required for Xenopus Anterior Neural Development

Lee, S., Lau, A. T. Y., Jeong, C., Shim, J., Kim, H.-G., Kim, J., Bode, A. M., & Dong, Z. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.127233 · Cited by 11 · see citing works

Changes in Liver Gene Expression of Azin1 Knock-out Mice

Wan, T., Hu, Y., Huang, A.-L., Yamamura, K.-I., & Tang, H. (2010) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2010-7-816 · Cited by 7 · see citing works

LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control

Dommann, N., Gavini, J., Sánchez‐Taltavull, D., Baier, F. A., Birrer, F., Loforese, G., Candinas, D., & Stroka, D. (2022) · FEBS Letters · doi:10.1002/1873-3468.14371 · Cited by 3 · see citing works

Targeting Cyclin-Dependent Kinases for Cancer Therapy

Johnson, N., & Shapiro, G. I. (2010) · Springer eBooks · doi:10.1007/978-1-4419-1770-6_11 · Cited by 2 · see citing works

Fanconi Anemia: A Pathway of Hematopoiesis and Cancer Predisposition

Suliman, A. Y., Smith, F. O., & Kupfer, G. M. (2018) · Pediatric oncology · doi:10.1007/978-3-319-61421-2_4 · Cited by 2 · see citing works

Haemostatic products as a potential therapy for vesicant-contaminated wounds

Hall, C. A. (2012) · University of Birmingham Institutional Research Archive (University of Birmingham) · Cited by 2 · see citing works

Rad24-RFC loads the 9-1-1 clamp by inserting DNA from the top of a wide-open ring, opposite the mechanism of RFC/PCNAPreprint

Zheng, F., Georgescu, R. E., Yao, N. Y., O’Donnell, M. E., & Li, H. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.01.462756 · Cited by 2 · see citing works

Knockdown of Chk1 inhibits proliferation and promotes apoptosis in mouse granulosa cells and its regulation mechanism by miR-15a and miR-16

Liu, X.-M., Chen, F., Zhang, F., Xi, H., & Zhao, J. (2022) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-022-00705-7 · Cited by 1 · see citing works

The E2F1-responsive microRNA-449 promotes apoptosis

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DNA damage control: regulation and functions of checkpoint kinase 1

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