The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Do age-related macular degeneration and cardiovascular disease share common antecedents?
Abstract
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss and blindness in elderly Americans. The etiology of this condition remains unknown and treatment options are limited. Some epidemiological findings point to a cardiovascular risk profile among persons with AMD. Documented risk factors for cardiovascular disease (such as age, smoking, hypertension, hypercholesterolemia, post-menopausal estrogen use, diabetes, and dietary intake of fats, alcohol and antioxidants) have also been associated with AMD in some studies. This raises the possibility that the causal pathways for cardiovascular disease and AMD may share similar risk factors. Future research on this hypothesis could lead to important insights into etiologic factors for AMD. Research could also identify modifiable risk factors and suggest new treatment options which could prevent AMD, slow its progression, or reduce visual loss. Susceptible individuals could then be targeted for improved health promotion and disease prevention measures for this disabling and highly prevalent disorder.
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Cites
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Cited by
The epidemiology of age-related macular degeneration
Klein, R., Peto, T., Bird, A., & Vannewkirk, M. R. (2004) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2003.11.069 · Cited by 932
Oxidative damage-induced inflammation initiates age-related macular degeneration
Hollyfield, J. G., Bonilha, V. L., Rayborn, M. E., Yang, X., Shadrach, K. G., Lu, L., Ufret, R. L., Salomon, R. G., & Perez, V. L. (2008) · Nature Medicine · doi:10.1038/nm1709 · Cited by 710
Relationship between RPE and Choriocapillaris in Age-Related Macular Degeneration
McLeod, D. S., Grebe, R., Bhutto, I., Merges, C., Baba, T., & Lutty, G. A. (2009) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.09-3639 · Cited by 567
Seddon, J. M. (2005) · Archives of Ophthalmology · doi:10.1001/archopht.123.3.321 · Cited by 446
Self-citationNeale, B. M., Fagerness, J., Reynolds, R., Sobrin, L., Parker, M., Raychaudhuri, S., Tan, P. L., Oh, E. C., Merriam, J. E., Souied, E., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0912019107 · Cited by 442
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Metadata
- Authors
- Snow, K. K., & Seddon, J. M.
- Venue
- Ophthalmic Epidemiology
- Publisher
- Swets & Zeitlinger Publishers
- Published
- 1999-01
- Volume
- 6
- Issue
- 2
- Pages
- 125-143
- ISSN
- 0928-6586 (ISSN-L)
- 1744-5086
- OpenAlex
- W2004194747
- Cited by
- 274
- References
- 21
- FWCI
- 3.79
- Type
- journal article
- Language
- en
- Open access
- closed
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- Snow, K. K., & Seddon, J. M. (1999). Do age-related macular degeneration and cardiovascular disease share common antecedents? Ophthalmic Epidemiology. https://doi.org/10.1076/opep.6.2.125.1558
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
