Chemistry and metabolism of lipids in the vertebrate retina

A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss: AREDS Report No. 8

(2001) · Archives of Ophthalmology · doi:10.1001/archopht.119.10.1417 · Cited by 3,285 · see citing works

Retinitis pigmentosa

Hartong, D. T., Berson, E. L., & Dryja, T. P. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69740-7 · Cited by 2,924 · see citing works

The Retinal Pigment Epithelium in Visual Function

Strauss, O. (2005) · Physiological Reviews · doi:10.1152/physrev.00021.2004 · Cited by 2,828 · see citing works

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration

Crabb, J. W., Miyagi, M., Gu, X., Shadrach, K., West, K. A., Sakaguchi, H., Kamei, M., Hasan, A., Yan, L., Rayborn, M. E., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222551899 · Cited by 1,208 · see citing works

Essential fatty acids in growth and development

Innis, S. M. (1991) · Progress in Lipid Research · doi:10.1016/0163-7827(91)90006-q · Cited by 921 · see citing works

Insights into the Function of Rim Protein in Photoreceptors and Etiology of Stargardt's Disease from the Phenotype in abcr Knockout Mice

Weng, J., Mata, N. L., Azarian, S. M., Tzekov, R. T., Birch, D. G., & Travis, G. H. (1999) · Cell · doi:10.1016/s0092-8674(00)80602-9 · Cited by 881 · see citing works

Oxidative damage-induced inflammation initiates age-related macular degeneration

Hollyfield, J. G., Bonilha, V. L., Rayborn, M. E., Yang, X., Shadrach, K. G., Lu, L., Ufret, R. L., Salomon, R. G., & Perez, V. L. (2008) · Nature Medicine · doi:10.1038/nm1709 · Cited by 710 · see citing works

Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer’s, and other neurodegenerative diseases

Bazan, N. G., Molina, M. F., & Gordon, W. C. (2011) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.012809.104635 · Cited by 441 · see citing works

The cell biology of the retinal pigment epithelium

Lakkaraju, A., Umapathy, A., Tan, L. X., Daniele, L., Philp, N. J., Boesze-Battaglia, K., & Williams, D. S. (2020) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100846 · Cited by 422 · see citing works

The bisretinoids of retinal pigment epithelium

Sparrow, J. R., Gregory-Roberts, E., Yamamoto, K., Blonska, A., Ghosh, S. K., Ueda, K., & Zhou, J. (2012) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2011.12.001 · Cited by 392 · see citing works

Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors

Bazan, N. G. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.03.005 · Cited by 353 · see citing works

Prospective study of dietary fat and the risk of age-related macular degeneration

Cho, E., Hung, S., Willett, W. C., Spiegelman, D., Rimm, E. B., Seddon, J. M., Colditz, G. A., & Hankinson, S. E. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.2.209 · Cited by 350 · see citing works

The Relationship of Dietary Lipid Intake and Age-Related Macular Degeneration in a Case-Control Study: AREDS Report No. 20

(2007) · Archives of Ophthalmology · doi:10.1001/archopht.125.5.671 · Cited by 283 · see citing works

Dietary ω-3 Fatty Acid and Fish Intake in the Primary Prevention of Age-Related Macular Degeneration: A Systematic Review and Meta-analysis

Chong, E. W.-T. (2008) · Archives of Ophthalmology · doi:10.1001/archopht.126.6.826 · Cited by 279 · see citing works

Phospholipid meets all-trans-retinal: the making of RPE bisretinoids

Sparrow, J. R., Wu, Y., Kim, C. Y., & Zhou, J. (2010) · Journal of Lipid Research · doi:10.1194/jlr.r000687 · Cited by 193 · see citing works

ω–3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study

SanGiovanni, J. P., Agrón, E., Meleth, A. D., Reed, G. F., Sperduto, R. D., Clemons, T. E., & Chew, E. Y. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27594 · Cited by 186 · see citing works

Associations between Lutein, Zeaxanthin, and Age-Related Macular Degeneration: An Overview

Carpentier, S., Knaus, M., & Suh, M. (2009) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390802066979 · Cited by 182 · see citing works

Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant <i>ELOVL4</i> transgenic mice: A model for macular degeneration

Karan, G., Lillo, C., Yang, Z., Cameron, D. J., Locke, K. G., Zhao, Y., Thirumalaichary, S., Li, C., Birch, D. G., Vollmer-Snarr, H. R., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407698102 · Cited by 182 · see citing works

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

Agbaga, M.-P., Mandal, M. N. A., & Anderson, R. E. (2010) · Journal of Lipid Research · doi:10.1194/jlr.r005025 · Cited by 167 · see citing works

Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium

Sun, M., Finnemann, S. C., Febbraio, M., Shan, L., Annangudi, S. P., Podrez, E. A., Hoppe, G., Darrow, R., Organisciak, D. T., Salomon, R. G., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m509769200 · Cited by 165 · see citing works

Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for stargardt macular degeneration

Radu, R. A., Hu, J., Yuan, Q., Welch, D. L., Makshanoff, J., Lloyd, M., McMullen, S., Travis, G. H., & Bok, D. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.191866 · Cited by 157 · see citing works

Mfsd2a is a transporter for the essential ω-3 fatty acid docosahexaenoic acid (DHA) in Eye and is important for photoreceptor cell development

Wong, B. H., Chan, J. P., Cazenave-Gassiot, A., Poh, R. W., Foo, J. C., Galam, D. L. A., Ghosh, S., Nguyen, L. N., Barathi, V. A., Yeo, S. W., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.721340 · Cited by 155 · see citing works

Docosanoids and elovanoids from omega-3 fatty acids are pro-homeostatic modulators of inflammatory responses, cell damage and neuroprotection

Bazan, N. G. (2018) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2018.09.003 · Cited by 148 · see citing works

Dietary ω-3 Fatty Acid and Fish Intake and Incident Age-Related Macular Degeneration in Women

Christen, W. G. (2011) · Archives of Ophthalmology · doi:10.1001/archophthalmol.2011.34 · Cited by 138 · see citing works

New insights into retinoid metabolism and cycling within the retina

Tang, P. H., Kono, M., Koutalos, Y., Ablonczy, Z., & Crouch, R. K. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2012.09.002 · Cited by 122 · see citing works

Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival

Rice, D. S., Calandria, J. M., Gordon, W. C., Jun, B., Zhou, Y., Gelfman, C. M., Li, S., Jin, M., Knott, E. J., Chang, B., et al. (2015) · Nature Communications · doi:10.1038/ncomms7228 · Cited by 124 · see citing works

Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: implications for age-related macular degeneration

Ebrahem, Q., Renganathan, K., Sears, J., Vasanji, A., Gu, X., Lu, L., Salomon, R. G., Crabb, J. W., & Anand-Apte, B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601552103 · Cited by 117 · see citing works

Phagocytosis-dependent ketogenesis in retinal pigment epithelium

Reyes-Reveles, J., Dhingra, A., Alexander, D., Bragin, A., Philp, N. J., & Boesze-Battaglia, K. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.770784 · Cited by 116 · see citing works

Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration

Molday, R. S., Garces, F. A., Scortecci, J. F., & Molday, L. L. (2022) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.101036 · Cited by 107 · see citing works

Current Clinical Applications of Ω‐6 and Ω‐3 Fatty Acids

Lee, S., Gura, K. M., Kim, S., Arsenault, D. A., Bistrian, B. R., & Puder, M. (2006) · Nutrition in Clinical Practice · doi:10.1177/0115426506021004323 · Cited by 100 · see citing works

Retinal pigment epithelial cells play a central role in the conservation of docosahexaenoic acid by photoreceptor cells after shedding and phagocytosis

Gordon, W. C., de Turco, E. B. R., & Bazan, N. G. (1992) · Current Eye Research · doi:10.3109/02713689209069169 · Cited by 89 · see citing works

Deficiency of a Retinal Dystrophy Protein, Acyl-CoA Binding Domain-containing 5 (ACBD5), Impairs Peroxisomal β-Oxidation of Very-long-chain Fatty Acids

Yagita, Y., Shinohara, K., Abe, Y., Nakagawa, K., Al-Owain, M., Alkuraya, F. S., & Fujiki, Y. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.760090 · Cited by 85 · see citing works

Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration

Molday, R. S., & Zhang, K. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.07.002 · Cited by 82 · see citing works

An Hypothesis to Account for the Renewal of Outer Segments in Rod and Cone Photoreceptor Cells: Renewal as a Surrogate Antioxidant

Winkler, B. S. (2008) · Investigative Opthalmology &amp; Visual Science · doi:10.1167/iovs.08-1785 · Cited by 50 · see citing works

Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal dysfunction in a model of Stargardt disease and human retinas

Anderson, D. M. G., Ablonczy, Z., Koutalos, Y., Hanneken, A. M., Spraggins, J. M., Calcutt, M. W., Crouch, R. K., Caprioli, R. M., & Schey, K. L. (2017) · Scientific Reports · doi:10.1038/s41598-017-17402-1 · Cited by 48 · see citing works

Compartmentalization of Photoreceptor Sensory Cilia

Barnes, C. L., Malhotra, H., & Calvert, P. D. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.636737 · Cited by 44 · see citing works

Rapid and selective uptake, metabolism, and cellular distribution of docosahexaenoic acid among rod and cone photoreceptor cells in the frog retina.

Rodriguez de Turco, E., Gordon, W., & Bazan, N. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-11-03667.1991 · Cited by 44 · see citing works

Peroxisome proliferator-activated receptor and age-related macular degeneration

Herzlich, A. A., Tuo, J., & Chan, C.-C. (2008) · PPAR Research · doi:10.1155/2008/389507 · Cited by 43 · see citing works

Preferential uptake and metabolism of docosahexaenoic acid in membrane phospholipids from rod and cone photoreceptor cells of human and monkey retinas

de Turco, E. B. R., Gordon, W. C., Peyman, G. A., & Bazan, N. G. (1990) · Journal of Neuroscience Research · doi:10.1002/jnr.490270413 · Cited by 39 · see citing works

<i>N‐tert‐butyl</i> hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration

Voloboueva, L. A., Killilea, D. W., Atamna, H., & Ames, B. N. (2007) · The FASEB Journal · doi:10.1096/fj.07-8396com · Cited by 33 · see citing works

Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B)

Daniele, L. L., Caughey, J., Volland, S., Sharp, R. C., Dhingra, A., Williams, D. S., Philp, N. J., & Boesze-Battaglia, K. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00185.2019 · Cited by 16 · see citing works

Rod-specific downregulation of omega-3 very-long-chain polyunsaturated fatty acid pathway in age-related macular degeneration

Gordon, W. C., Kautzmann, M.-A. I., Jun, B., Cothern, M. L., Fang, Z., & Bazan, N. G. (2023) · Experimental Eye Research · doi:10.1016/j.exer.2023.109639 · Cited by 14 · see citing works