CoChat
Sign Up
Cited by 990Fatty Acid Research and HealthNutritional Studies and DietCardiac electrophysiology and arrhythmias

Fish Consumption and Risk of Sudden Cardiac Death

Albert, Christine M.·1998·JAMA
DOI 10.1001/jama.279.1.23
Open this paper in CoChat — free account

Abstract

CONTEXT: Dietary fish intake has been associated with a reduced risk of fatal cardiac end points, but not with nonfatal end points. Dietary fish intake may have a selective benefit on fatal arrhythmias and therefore sudden cardiac death. OBJECTIVE: To investigate prospectively the association between fish consumption and the risk of sudden cardiac death. DESIGN: Prospective cohort study. SETTING: The US Physicians' Health Study. PATIENTS: A total of 20 551 US male physicians 40 to 84 years of age and free of myocardial infarction, cerebrovascular disease, and cancer at baseline who completed an abbreviated, semiquantitative food frequency questionnaire on fish consumption and were then followed up to 11 years. MAIN OUTCOME MEASURE: Incidence of sudden cardiac death (death within 1 hour of symptom onset) as ascertained by hospital records and reports of next of kin. RESULTS: There were 133 sudden deaths over the course of the study. After controlling for age, randomized aspirin and beta carotene assignment, and coronary risk factors, dietary fish intake was associated with a reduced risk of sudden death, with an apparent threshold effect at a consumption level of 1 fish meal per week (P for trend=.03). For men who consumed fish at least once per week, the multivariate relative risk of sudden death was 0.48 (95% confidence interval, 0.24-0.96; P=.04) compared with men who consumed fish less than monthly. Estimated dietary n-3 fatty acid intake from seafood also was associated with a reduced risk of sudden death but without a significant trend across increasing categories of intake. Neither dietary fish consumption nor n-3 fatty acid intake was associated with a reduced risk of total myocardial infarction, nonsudden cardiac death, or total cardiovascular mortality. However, fish consumption was associated with a significantly reduced risk of total mortality. CONCLUSION: These prospective data suggest that consumption of fish at least once per week may reduce the risk of sudden cardiac death in men.

Integrity signals

Registry

Crossref · 10.1001/jama.279.1.23

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Albert, C. M.
Affiliations
Brigham and Women's Hospital (US)
Corresponding author
Albert, Christine M.
ORCID
Albert, Christine M.
Venue
JAMA
Publisher
American Medical Association (AMA)
Published
1998-01-07
Volume
279
Issue
1
Pages
23
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.279.1.23
OpenAlex
W2087878463
Cited by
990
References
33
Citations by year
2026: 1 · 2025: 7 · 2024: 10 · 2023: 7 · 2022: 13 · 2021: 14 · 2020: 16 · 2019: 13 · 2018: 19 · 2017: 27 · 2016: 17 · 2015: 19 · 2014: 39 · 2013: 38 · 2012: 42
FWCI
54.24
Type
journal article
Language
en
Open access
closed
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Heart, Lung, and Blood Institute (HL 26490)
  • National Cancer Institute (R01CA040360, CA 34944, CA 40360)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
fish consumption, sudden cardiac death, omega-3 fatty acids, seafood, dietary intake, myocardial infarction, cardiovascular mortality, all-cause mortality, cardiac arrhythmias, Physicians' Health Study
MeSH terms
Adult, Aged, Aged, 80 and over, Diet, Health Surveys, Humans, Male, Middle Aged, Prospective Studies, Risk, United States, Cohort Studies, Fatty Acids, Omega-3, Incidence, Multivariate Analysis, Proportional Hazards Models, Death, Sudden, Cardiac, Seafood

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review