The use of macrocyclic lactones in the control and prevention of heartworm and other parasites in dogs and cats.
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Monthly oral ivermectin treatment for 2 years at a dose of 24 g/kg of body weight reduces parasite load by 65% compared to untreated cats.
“Monthly ivermectin treatment by oral administration for 2 years at a dose of 24 g/kg of body weight was shown to reduce the parasite load by 65% compared to that of untreated cats (169).”
From Human and animal dirofilariasis: The emergence of a zoonotic mosaic (2012) · cites this paper as [169]
Topical selamectin is active against fleas and other major parasites of companion animals.
“Topical selamectin can be used to prevent cardio-pulmonary dirofilariosis in dogs and cats and, as mentioned above, this formulation is active against fleas and other major parasites of companion animals [107,138,139].”
From Fleas infesting pets in the era of emerging extra-intestinal nematodes (2013) · cites this paper as [139]
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Human and animal dirofilariasis: The emergence of a zoonotic mosaic
Simón, F., Siles-Lucas, M., Morchón, R., González-Miguel, J., Mellado, I., Carretón, E., & Montoya-Alonso, J. A. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.00012-12 · Cited by 834 · see citing works
“Monthly ivermectin treatment by oral administration for 2 years at a dose of 24 g/kg of body weight was shown to reduce the parasite load by 65% compared to that of untreated cats (169).”
ResultChapter 4 Heartworm Disease in Animals and Humans
McCall, J. W., Genchi, C., Kramer, L. H., Guerrero, J., & Venco, L. (2008) · Advances in Parasitology · doi:10.1016/s0065-308x(08)00204-2 · Cited by 609 · see citing works
Self-citationCanine and feline cardiopulmonary parasitic nematodes in Europe: emerging and underestimated
Traversa, D., Di Cesare, A., & Conboy, G. (2010) · Parasites & Vectors · doi:10.1186/1756-3305-3-62 · Cited by 351 · see citing works
McCall, J. W. (2005) · Veterinary Parasitology · doi:10.1016/j.vetpar.2005.04.005 · Cited by 117 · see citing works
“These drugs are among the safest of all products prescribed for use in animals (Guerrero et al., 2002), yet a 2001 survey of more than 18,000 veterinary clinics in the United States identified more than 240,000 dogs and 3000 cats infected with D.”
BackgroundInfluentialSelf-citationThe emergence of macrocyclic lactone resistance in the canine heartworm,Dirofilaria immitis.
Wolstenholme, A. J., Evans, C. C., JIMENEZ, P. D., & Moorhead, A. R. (2015) · Parasitology · doi:10.1017/s003118201500061x · Cited by 87 · see citing works
“…2002; Dupuy et al. 2004) Since the development of adult parasites from invading L3 takes several months, there is a fairly long window of opportunity (up to 2 months) after infection has taken place when the drugs can remove the larvae and prevent the development of disease (Guerrero et al. 2002).”
BackgroundVenco, L., McCall, J. W., Guerrero, J., & Genchi, C. (2004) · Veterinary Parasitology · doi:10.1016/j.vetpar.2004.06.024 · Cited by 65 · see citing works
“These values seem to be lower than those previously reported in experimental studies (McCall et al., 1995, 1996, 2001; Guerrero et al., 2002).”
BackgroundResultSelf-citationFleas infesting pets in the era of emerging extra-intestinal nematodes
Traversa, D. (2013) · Parasites & Vectors · doi:10.1186/1756-3305-6-59 · Cited by 53 · see citing works
“fleas and other major parasites of companion animals [107,138,139].”
BackgroundThe Insecticidal Macrocyclic Lactones
Rugg, D., Buckingham, S. D., Sattelle, D. B., et al. (2005) · Elsevier eBooks · doi:10.1016/b0-44-451924-6/00065-x · Cited by 44 · see citing works
Ferroglio, E., Rossi, L., Tomio, E., Schenker, R., & Bianciardi, P. (2008) · Veterinary Parasitology · doi:10.1016/j.vetpar.2008.03.011 · Cited by 35 · see citing works
Pharmacological approaches towards rationalizing the use of endoparasitic drugs in small animals
Bruni, S. F. S., JONES, D. G., & McKellar, Q. (2006) · Journal of Veterinary Pharmacology and Therapeutics · doi:10.1111/j.1365-2885.2006.00806.x · Cited by 25 · see citing works
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
de Jesus, A. P., Holsback, L., Selingardi, M. S., Cardoso, M. J. L., Cabral, L. D. R., & Santos, T. R. (2015) · Semina Ciências Agrárias · doi:10.5433/1679-0359.2015v36n6p3731 · Cited by 16 · see citing works
Prevalence of Toxocara canis eggs in dog faeces from public places of Florence, Italy
Papini, R. A., Campisi, E., Faggi, E., Pini, G., & Mancianti, F. (2012) · Helminthologia · doi:10.2478/s11687-012-0031-0 · Cited by 13 · see citing works
Knaus, M., Baker, C. F., Reinemeyer, C. R., Chester, S. T., Rosentel, J. K., & Rehbein, S. (2014) · Veterinary Parasitology · doi:10.1016/j.vetpar.2014.02.036 · Cited by 12 · see citing works
“Macrocyclic lactones have been used as anthelmintics in cats for several years and provide excellent efficacy against infections with various nematode parasites of pets (reviewed by Guerrero et al., 2002; Nolan and Lok, 2012).”
BackgroundAbuse of Chemical Substances Cause Poisoning in Dogs and Cats: A Review
Lorsirigool, A., Sudjaroen, Y., & Kulnides, N. (2022) · Indian Journal of Forensic Medicine & Toxicology · doi:10.37506/ijfmt.v16i4.18553 · Cited by 3 · see citing works
Current Antifilarial Drugs – Mechanisms of Action
Geary, T. G., Long, A., & Tritten, L. (2022) · Wiley eBooks · doi:10.1002/9783527823413.ch10 · Cited by 3 · see citing works
- Authors
- Guerrero, J., McCall, J. W., & Genchi, C.
- Affiliations
- University of Pennsylvania (US)
- ORCID
- Guerrero, J.
- Venue
- Macrocyclic lactones in antiparasitic therapy
- Publisher
- CAB International
- Published
- 2002-01
- Pages
- 353-369
- OpenAlex
- W2485658793
- Cited by
- 17
- References
- 0
- Citations by year
- 2022: 2 · 2015: 2 · 2014: 1 · 2013: 1 · 2012: 2
- FWCI
- 5.27
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- CABI Publishing eBooks (publishedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Veterinary › Small Animals › Veterinary Pharmacology and Anesthesia
- Keywords
- macrocyclic lactones, heartworm disease, Dirofilaria immitis, anthelmintic treatment, heartworm prevention, dogs, cats, helminths
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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