Fetal Programming of Cardiovascular Function through Exposure to Maternal Undernutrition
Open accessAbstract
A substantial and robust body of epidemiological evidence indicates that prenatal dietary experience may be a factor determining cardiovascular disease risk. Retrospective cohort studies indicate that low birth weight and disproportion at birth are powerful predictors of later disease risk. This prenatal influence on non-communicable disease in later life has been termed programming. Maternal nutritional status has been proposed to be the major programming influence on the developing fetus. The evidence from epidemiological studies of nutrition, fetal development and birth outcome is, however, often weak and inconclusive. The validity of the nutritional programming concept is highly dependent on experimental studies in animals. The feeding of low-protein diets in rat pregnancy results in perturbations in fetal growth and dimensions at birth. The offspring of rats fed low-protein diets exhibit a number of metabolic and physiological disturbances, and are consistently found to have high blood pressure from early postnatal life. This experimental model has been used to explore potential mechanisms of programming through which maternal diet may programme the cardiovascular function of the fetus. Indications from this work are that fetal exposure to maternally-derived glucocorticoids plays a key role in the programming mechanism. Secondary to this activity, the fetal hypothalamic–pituitary–adrenal axis may stimulate renin–angiotensin system activity, resulting in increased vascular resistance and hypertension.
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Individuals whose gestation coincided with the Dutch Famine exhibited increased susceptibility to obesity, insulin resistance, and cardiovascular disease in adulthood.
“Individuals whose gestation coincided with the famine exhibited increased susceptibility to obesity, insulin resistance, and cardiovascular disease in adulthood, strongly implicating fetal adaptive responses to nutrient scarcity in shaping lifelong disease risk [10,11].”
From Maternal Overnutrition and Fetal Programming: Long-Term Metabolic, Cognitive, and Epigenetic Consequences (2026) · cites this paper as [10]
Cites
Glucose tolerance in adults after prenatal exposure to famine
Ravelli, A., van der Meulen, J., Michels, R., Osmond, C., Barker, D., Hales, C., & Bleker, O. (1998) · The Lancet · doi:10.1016/s0140-6736(97)07244-9 · Cited by 1,606 · see citing works
Diet and Health: What Should We Eat?
Willett, W. C. (1994) · Science · doi:10.1126/science.8160011 · Cited by 1,008 · see citing works
Mothers, Babies, and Disease in Later Life
Gillman, M. W. (1995) · BMJ · doi:10.1136/bmj.310.6971.68a · Cited by 880 · see citing works
Glucocorticoid exposure in utero: new model for adult hypertension
Benediktsson, R., Lindsay, R. S., Noble, J., Seckl, J. R., & Edwards, C. R. W. (1993) · The Lancet · doi:10.1016/0140-6736(93)90138-7 · Cited by 862 · see citing works
Mothers, Babies and Disease in Later Life
Barker, D. J. P., & Barker, D. J. P. (1994) · Medical Entomology and Zoology · Cited by 860 · see citing works
PREMATURE DELIVERY OF FOETAL LAMBS INFUSED WITH GLUCOCORTICOIDS
LIGGINS, G. C. (1969) · Journal of Endocrinology · doi:10.1677/joe.0.0450515 · Cited by 817 · see citing works
Kwong, W. Y., Wild, A. E., Roberts, P., Willis, A. C., & Fleming, T. P. (2000) · Development · doi:10.1242/dev.127.19.4195 · Cited by 798 · see citing works
Langley‐Evans, S. C., & Jackson, A. A. (1994) · Clinical Science · doi:10.1042/cs0860217 · Cited by 688 · see citing works
Self-citationFetal growth and coronary heart disease in South India
Stein, C., Fall, C., Kumaran, K., Osmond, C., Barker, D. J. P., & Cox, V. (1996) · The Lancet · doi:10.1016/s0140-6736(96)04547-3 · Cited by 607 · see citing works
Maternal nutrition in early and late pregnancy in relation to placental and fetal growth
Godfrey, K., Robinson, S., Barker, D., Osmond, C., & Cox, V (1996) · BMJ · doi:10.1136/bmj.312.7028.410 · Cited by 604 · see citing works
The effect of intrauterine growth retardation on the development of renal nephrons
Hinchliffe, S. A., Lynch, M. R. J., Sargent, P. H., Howard, C. V., & van Velzen, D. (1992) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1992.tb13726.x · Cited by 571 · see citing works
Edwards, C. R. W., Benediktsson, R., Lindsay, R. S., & Seckl, J. R. (1993) · The Lancet · doi:10.1016/0140-6736(93)90148-a · Cited by 549 · see citing works
Langley‐Evans, S. C., Welham, S. J. M., & Jackson, A. A. (1999) · Life Sciences · doi:10.1016/s0024-3205(99)00022-3 · Cited by 547 · see citing works
Self-citationPrenatal Exposure to Prednisone in Humans and Animals Retards Intrauterine Growth
Reinisch, J. M., Simon, N. G., Karow, W. G., & Gandelman, R. J. (1978) · Science · doi:10.1126/science.705336 · Cited by 544 · see citing works
Forsen, T., Eriksson, J. G., Tuomilehto, J., Osmond, C., & Barker, D. J. P. (1999) · BMJ · doi:10.1136/bmj.319.7222.1403 · Cited by 481 · see citing works
Langley‐Evans, S. C., Phillips, G. J., Benediktsson, R., Gardner, D. S., Edwards, C. R. W., Jackson, A. A., & Seckl, J. R. (1996) · Placenta · doi:10.1016/s0143-4004(96)80010-5 · Cited by 415 · see citing works
Self-citationLow Birth Weight Predicts Elevated Plasma Cortisol Concentrations in Adults From 3 Populations
Phillips, D. I. W., Walker, B. R., Reynolds, R. M., Flanagan, D., Wood, P. J., Osmond, C., Barker, D. J. P., & Whorwood, C. B. (2000) · Hypertension · doi:10.1161/01.hyp.35.6.1301 · Cited by 389 · see citing works
Fetal Growth and Glucose and Insulin Metabolism in Four‐year‐old Indian Children
Yajnik, C. S., Fall, C. H. D., Vaidya, U., Pandit, A. N., Bavdekar, A., Bhat, D., Osmond, C., Hales, C. N., & Barker, D. J. P. (1995) · Diabetic Medicine · doi:10.1111/j.1464-5491.1995.tb00487.x · Cited by 375 · see citing works
Children born during The Siege of Leningrad in 1942
Antonov, A. N. (1947) · The Journal of Pediatrics · doi:10.1016/s0022-3476(47)80160-x · Cited by 370 · see citing works
Woodall, S., Johnston, B. M., Breier, B. H., & Gluckman, P. D. (1996) · Pediatric Research · doi:10.1203/00006450-199609000-00012 · Cited by 366 · see citing works
Intrauterine growth retardation leads to a permanent nephron deficit in the rat
Merlet-Bénichou, C., Gilbert, T., Muffat‐Joly, M., Leli�vre-P�gorier, M., & Leroy, B. (1994) · Pediatric Nephrology · doi:10.1007/bf00865473 · Cited by 351 · see citing works
Diet in pregnancy and the offspring's blood pressure 40 years later
Campbell, D. M., Hall, M. H., Barker, D. J. P., Cross, J. F., Shiell, A. W., & Godfrey, K. M. (1996) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1996.tb09718.x · Cited by 344 · see citing works
Influence of maternal nutrition on outcome of pregnancy: prospective cohort study
Mathews, F., Yudkin, P. L., & Neil, A. (1999) · BMJ · doi:10.1136/bmj.319.7206.339 · Cited by 316 · see citing works
Lindsay, R. S., Lindsay, R. M., Edwards, C. R. W., & Seckl, J. R. (1996) · Hypertension · doi:10.1161/01.hyp.27.6.1200 · Cited by 301 · see citing works
Fishing in the Stream of Diabetes: From Measuring Insulin to the Control of Fetal Organogenesis
Hales, C. N., Desai, M., Ozanne, S. E., & Crowther, N. J. (1996) · Biochemical Society Transactions · doi:10.1042/bst0240341 · Cited by 299 · see citing works
A Randomized Controlled Trial of Prenatal Nutritional Supplementation in New York City
Rush, D., STEIN, Z. A., & Susser, M. W. (1980) · PEDIATRICS · doi:10.1542/peds.65.4.683 · Cited by 274 · see citing works
Langley‐Evans, S. C., Welham, S. J. M., Sherman, R. C., & Jackson, A. A. (1996) · Clinical Science · doi:10.1042/cs0910607 · Cited by 265 · see citing works
Self-citationFewer nephrons at birth: A missing link in the etiology of essential hypertension?
Mackenzie, H. S., & Brenner, B. M. (1995) · American Journal of Kidney Diseases · doi:10.1016/0272-6386(95)90161-2 · Cited by 258 · see citing works
Langley‐Evans, S. C., Gardner, D. S., & Jackson, A. A. (1996) · Journal of Nutrition · doi:10.1093/jn/126.6.1578 · Cited by 229 · see citing works
Self-citationFetal growth and cardiovascular risk factors in Jamaican schoolchildren
Forrester, T., Wilks, R., Bennett, F., SIMEON, D. T., Osmond, C., Allen, M., Chung, A. P., & Scott, P. (1996) · BMJ · doi:10.1136/bmj.312.7024.156 · Cited by 224 · see citing works
Hoy, W. E., Mathews, J. D., McCredie, D. A., Pugsley, D. J., Hayhurst, B. G., Rees, M., Kile, E., Walker, K. A., & Wang, Z. (1998) · Kidney International · doi:10.1046/j.1523-1755.1998.00099.x · Cited by 219 · see citing works
Langley‐Evans, S. C. (1997) · Journal of Hypertension · doi:10.1097/00004872-199715050-00010 · Cited by 216 · see citing works
Self-citationSize at birth and adrenocortical function in childhood
Clark, P. M., Hindmarsh, P. C., Shiell, A. W., Law, C., Honour, J. W., & Barker, D. J. P. (1996) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1996.8560864.x · Cited by 200 · see citing works
Maternal nutritional status in pregnancy and blood pressure in childhood
Godfrey, K. M., Forrester, T., Barker, D. J. P., Jackson, A. A., Landman, J. P., Hall, J. S. E., Cox, V., & Osmond, C. (1994) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1994.tb11911.x · Cited by 188 · see citing works
Langley‐Evans, S. C., Phillips, G. J., & Jackson, A. A. (1994) · Clinical Nutrition · doi:10.1016/0261-5614(94)90056-6 · Cited by 183 · see citing works
Self-citationLangley‐Evans, S. C. (2000) · International Journal of Food Sciences and Nutrition · doi:10.1080/096374800100859 · Cited by 182 · see citing works
Self-citationEffect of cortisol on blood pressure and vascular reactivity in the ovine fetus
Tangalakis, K., Lumbers, E. R., Moritz, K. M., Towstoless, M., & Wintour, E. M. (1992) · Experimental Physiology · doi:10.1113/expphysiol.1992.sp003637 · Cited by 173 · see citing works
Increased birthweight after prenatal dietary supplementation of rural African women
Prentice, A. M., Cole, T. J., Foord, F., Lamb, W. H., & Whitehead, R. G. (1987) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/46.6.912 · Cited by 170 · see citing works
11β-Hydroxysteroid dehydrogenases: Key enzymes in determining tissue-specific glucocorticoid effects
Edwards, C. R. W., Benediktsson, R., Lindsay, R. S., & Seckl, J. R. (1996) · Steroids · doi:10.1016/0039-128x(96)00033-5 · Cited by 170 · see citing works
Maternal nutritional status in pregnancy and blood pressure in childhood
(1995) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(95)90331-3 · Cited by 168 · see citing works
Nwagwu, M. O., Cook, A., & Langley‐Evans, S. C. (2000) · British Journal Of Nutrition · doi:10.1017/s0007114500000118 · Cited by 166 · see citing works
Self-citationMaternal Protein Deficiency Causes Hypermethylation of DNA in the Livers of Rat Fetuses
Rees, W. D., Hay, S. M., Brown, D. S., Antipatis, C., & Palmer, R. M. (2000) · Journal of Nutrition · doi:10.1093/jn/130.7.1821 · Cited by 164 · see citing works
Konje, J. C., Bell, S. C., Morton, J. J., Chazal, R. D., & Taylor, D. J. (1996) · Clinical Science · doi:10.1042/cs0910169 · Cited by 155 · see citing works
Langley‐Evans, S. C., Gardner, D. S., & Jackson, A. A. (1996) · Reproduction · doi:10.1530/jrf.0.1060307 · Cited by 150 · see citing works
Self-citationSherman, R. C., & Langley‐Evans, S. C. (1998) · Clinical Science · doi:10.1042/cs0940373 · Cited by 150 · see citing works
Self-citationLangley‐Evans, S. C., & Jackson, A. A. (1995) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(94)00177-u · Cited by 147 · see citing works
Self-citationSherman, R. C., & Langley‐Evans, S. C. (2000) · Clinical Science · doi:10.1042/cs0980269 · Cited by 145 · see citing works
Self-citationBirth weight and later socioeconomic disadvantage: evidence from the 1958 British cohort study
Bartley, M., Power, C., Blane, D., Smith, G. D., & Shipley, M. J. (1994) · BMJ · doi:10.1136/bmj.309.6967.1475 · Cited by 135 · see citing works
Altered glucose tolerance in rats exposed to maternal low protein diets in utero
Langley‐Evans, S. C., Browne, R. F., & Jackson, A. A. (1994) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(94)90124-4 · Cited by 134 · see citing works
Self-citationPersson, E., & Jansson, T. (1992) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1992.tb09356.x · Cited by 129 · see citing works
Placental weight, birth measurements, and blood pressure at age 8 years.
Moore, V., Miller, A., BOULTON, T. J. C., COCKINGTON, R. A., Craig, I. H., Magarey, A., & Robinson, J. S. (1996) · Archives of Disease in Childhood · doi:10.1136/adc.74.6.538 · Cited by 127 · see citing works
Maintenance of Maternal Diet-Induced Hypertension in the Rat Is Dependent on Glucocorticoids
Gardner, D. S., Jackson, A. A., & Langley‐Evans, S. C. (1997) · Hypertension · doi:10.1161/01.hyp.30.6.1525 · Cited by 126 · see citing works
Self-citationPrenatal Exposure to a Maternal Low Protein Diet Shortens Life Span in Rats
Sayer, A. A., Dunn, R. L., Langley‐Evans, S. C., & Cooper, C. C. (2001) · Gerontology · doi:10.1159/000052764 · Cited by 124 · see citing works
Self-citationEarly Protein Restriction and Obesity Independently Induce Hypertension in 1-Year-Old Rats
Petry, C. J., Ozanne, S. E., Wang, C. L., & Hales, C. N. (1997) · Clinical Science · doi:10.1042/cs0930147 · Cited by 124 · see citing works
Relationship between maternal nutritional status and infant’s weight and body proportions at birth
Thame, M. M., Wilks, R., McFarlane‐Anderson, N., Bennett, F., & Forrester, T. E. (1997) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600357 · Cited by 116 · see citing works
Effect of Maternal Protein Deficiency on Cellular Development in the Fetal Rat
Zeman, F. J., & Stanbrough, E. C. (1969) · Journal of Nutrition · doi:10.1093/jn/99.3.274 · Cited by 112 · see citing works
Effects of Maternal Protein Restriction on the Kidney of the Newborn Young of Rats
Zeman, F. J. (1968) · Journal of Nutrition · doi:10.1093/jn/94.2.111 · Cited by 111 · see citing works
Intrauterine Food Restriction is Associated with Obesity in Young Rats
Anguita, R. M., Sigulem, D. M., & Sawaya, A. L. (1993) · Journal of Nutrition · doi:10.1093/jn/123.8.1421 · Cited by 110 · see citing works
Enigma of fetal/infant-origins hypothesis
Kramer, M. S., & Joseph, K. S. (1996) · The Lancet · doi:10.1016/s0140-6736(05)65750-9 · Cited by 108 · see citing works
Type 2 11β-hydroxysteroid dehydrogenase in foetal and adult life
Stewart, P. M., Whorwood, C. B., & Mason, J. I. (1995) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(95)00195-6 · Cited by 105 · see citing works
Crowe, C., Dandekar, P., Fox, M., Dhingra, K., Bennet, L., & Hanson, M. A. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020986 · Cited by 104 · see citing works
Restricted fetal growth and the response to dietary cholesterol in the guinea pig
Kind, K. L., Clifton, P. M., Katsman, A. I., Tsiounis, M., Robinson, J. S., & Owens, J. A. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.277.6.r1675 · Cited by 102 · see citing works
Intrauterine programming of hypertension by glucocorticoids
Langley‐Evans, S. C. (1997) · Life Sciences · doi:10.1016/s0024-3205(96)00611-x · Cited by 99 · see citing works
Self-citationRelation between birth weight at term and systolic blood pressure in adolescence
Matthes, J. W. A., Lewis, P. A., Davies, D. P., & Bethel, J. (1994) · BMJ · doi:10.1136/bmj.308.6936.1074 · Cited by 97 · see citing works
Langley‐Evans, S. C. (1997) · Clinical Science · doi:10.1042/cs0930423 · Cited by 95 · see citing works
Self-citationIntrauterine programming of hypertension in the rat: Nutrient interactions
Langley‐Evans, S. C. (1996) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(96)00018-7 · Cited by 91 · see citing works
Self-citationLangley‐Evans, S. C., & Nwagwu, M. O. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00311-7 · Cited by 73 · see citing works
Self-citationNutritional Influences in Early Life upon Obesity and Body Proportions
Jackson, A. A., Langley‐Evans, S. C., & McCarthy, H. D. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514962.ch8 · Cited by 62 · see citing works
Self-citationPrenatal protein depletion and Δ9, Δ6 and Δ5 desaturases in the rat
Mercuri, O., Tomás, M. E. D., & Itarte, H. (1979) · Lipids · doi:10.1007/bf02533523 · Cited by 54 · see citing works
Châtelain, A., Dupouy, J. P., & Allaume, P. (1980) · PubMed · Cited by 54 · see citing works
Roach, H. I., & Clarke, N. M. P. (1999) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1999.14.8.1367 · Cited by 53 · see citing works
The Acute Phase Response of Adult Rats is Altered by in Utero Exposure to Maternal Low Protein Diets
Langley‐Evans, S. C., Seakins, M., Grimble, R. F., & Jackson, A. A. (1994) · Journal of Nutrition · doi:10.1093/jn/124.9.1588 · Cited by 52 · see citing works
Self-citationKidney Function of the Progeny of Rats Fed a Low Protein Diet
Hall, S., & Zeman, F. J. (1968) · Journal of Nutrition · doi:10.1093/jn/95.1.49 · Cited by 50 · see citing works
Iglesias-Barreira, V., Ahn, M., Reusens, B., Dahri, S., Hoet, J. J., & Remacle, C. (1996) · Endocrinology · doi:10.1210/endo.137.9.8756549 · Cited by 49 · see citing works
Langley‐Evans, S. C., Phillips Gary, J., & Jackson Alan, A. (1997) · Journal of Nutrition · doi:10.1093/jn/127.2.202 · Cited by 43 · see citing works
Self-citationCalder, P. C., & Yaqoob, P. (2000) · Nutrition Research · doi:10.1016/s0271-5317(00)00190-1 · Cited by 41 · see citing works
Role of glucocorticoids in programming of maternal diet-induced hypertension in the rat
Langley‐Evans, S. C., Phillips, G. J., Gardner, D. S., & Jackson, A. A. (1996) · The Journal of Nutritional Biochemistry · doi:10.1016/0955-2863(95)00197-2 · Cited by 41 · see citing works
Self-citationHastings-Roberts, M. M., & Zeman, F. J. (1977) · Journal of Nutrition · doi:10.1093/jn/107.6.973 · Cited by 40 · see citing works
Modest restriction of dietary protein during pregnancy in the rat: fetal and placental growth.
Levy, L., & Jackson, A. A. (1993) · PubMed · Cited by 38 · see citing works
Kornel, L., Prancan, A., Kanamarlapudi, N., Hynes, J., & Kuzianik, E. (1995) · Endocrine Research · doi:10.3109/07435809509030436 · Cited by 37 · see citing works
Harrap, S. B., Mirakian, C., Datodi, S. R., & Lever, A. F. (1994) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.1994.tb02479.x · Cited by 35 · see citing works
Doyle, W., Wynn, A., Crawford, M. A., & Wynn, S. (1992) · Journal of Nutritional Medicine · doi:10.3109/13590849208997980 · Cited by 26 · see citing works
A Randomized Controlled Trial of Prenatal Nutritional Supplementation
Jacobson, H. N. (1980) · PEDIATRICS · doi:10.1542/peds.65.4.835 · Cited by 25 · see citing works
Enzymes of the Gamma-Glutamyl Cycle Are Programmed in utero by Maternal Nutrition
Langley‐Evans, S. C., Wood, S., & Jackson, A. A. (1995) · Annals of Nutrition and Metabolism · doi:10.1159/000177839 · Cited by 24 · see citing works
Self-citationNarce, M., Poisson, J., Belleville, J., & Chanussot, B. (1992) · British Journal Of Nutrition · doi:10.1079/bjn19920121 · Cited by 15 · see citing works
Arishima, K., NAKAMA, S., Morikawa, Y., Hashimoto, Y., & EGUCHI, Y. (1977) · Journal of Endocrinology · doi:10.1677/joe.0.0720239 · Cited by 14 · see citing works
Sherman, R. C., Jackson, A. A., & Langley‐Evans, S. C. (1999) · Annals of Nutrition and Metabolism · doi:10.1159/000012773 · Cited by 12 · see citing works
Self-citationEARLY DIET, LATER CONSEQUENCES
(1991) · Nutrition & Food Science · doi:10.1108/eb059344 · Cited by 9 · see citing works
Prenatal Undernutrition Alters Postnatal Vascular Sensitivity to Angiotensin II
Gardner, D., Jackson, A. A., & Langley-Evans, S. (1998) · Clinical Science · doi:10.1042/cs094002pc · Cited by 6 · see citing works
Self-citationEffect of fetal exposure to gentamicin on phosphate transport in young rat kidney
Lelièvre-Pégorier, M., Euzet, S., & Merlet-Bénichou, C. (1993) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1993.265.6.f807 · Cited by 4 · see citing works
Comment: Preventing Adult Disease: Windows of Opportunity
Harrap, S. B., & Editorial Board (1998) · Clinical Science · doi:10.1042/cs0940337 · Cited by 2 · see citing works
Nutritionally-Induced Hypertension in the Rat is Programmed by Glucocorticoid Exposure
Gardner, D., Jackson, A. A., & Langley-Evans, S. (1998) · Clinical Science · doi:10.1042/cs095014pa · Cited by 2 · see citing works
Self-citationRees, W. D., & Hay, S. M. (1999) · Biochemical Society Transactions · doi:10.1042/bst027a049a · Cited by 1 · see citing works
Flagged first, then by citations
1 of the 94 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Developmental Origins of the Metabolic Syndrome: Prediction, Plasticity, and Programming
Mcmillen, I. C., & Robinson, J. S. (2005) · Physiological Reviews · doi:10.1152/physrev.00053.2003 · Cited by 1,910 · see citing works
Almond, D. (2006) · Journal of Political Economy · doi:10.1086/507154 · Cited by 1,190 · see citing works
Dietary Recommendations for Children and Adolescents: A Guide for Practitioners
Gidding, S. S., Dennison, B. A., Birch, L. L., Daniels, S. R., Gilman, M. W., Lichtenstein, A. H., Rattay, K. T., Steinberger, J., Stettler, N., & Horn, L. V. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2374 · Cited by 564 · see citing works
Intrauterine Programming of Physiological Systems: Causes and Consequences
Fowden, A. L., Giussani, D. A., & Forhead, A. J. (2006) · Physiology · doi:10.1152/physiol.00050.2005 · Cited by 511 · see citing works
Gidding, S. S., Dennison, B. A., Birch, L. L., Daniels, S. R., Gilman, M. W., Lichtenstein, A. H., Rattay, K. T., Steinberger, J., Stettler, N., & Van Horn, L. (2005) · Circulation · doi:10.1161/circulationaha.105.169251 · Cited by 465 · see citing works
Fleming, T. P., Kwong, W. Y., Porter, R., Ursell, E., Fesenko, I., Wilkins, A., Miller, D. J., Watkins, A. J., & Eckert, J. J. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.104.030957 · Cited by 330 · see citing works
Jansson, N., Pettersson, J., Haafiz, A., Ericsson, A., Palmberg, I., Tranberg, M., Ganapathy, V., Powell, T. L., & Jansson, T. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.550004 · Cited by 265 · see citing works
Jansson, N., Pettersson, J., Haafiz, A., Ericsson, A., Palmberg, I., Tranberg, M., Ganapathy, V., Powell, T. L., & Jansson, T. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.116509 · Cited by 261 · see citing works
Brawley, L., Itoh, S., Torrens, C., Barker, A. C., Bertram, C. E., Poston, L., & Hanson, M. A. (2003) · Pediatric Research · doi:10.1203/01.pdr.0000065731.00639.02 · Cited by 244 · see citing works
Bellinger, L., Lilley, C., & Langley‐Evans, S. C. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041224 · Cited by 232 · see citing works
Self-citationAnimal models of in utero exposure to a high fat diet: A review
Williams, L., Seki, Y., Vuguin, P. M., & Charron, M. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.07.006 · Cited by 223 · see citing works
Birth weight and subsequent blood pressure: A meta-analysis
Mu, M., Wang, S., Sheng, J., Zhao, Y., Li, H.-Z., Hu, C., & Tao, F. (2012) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2011.10.006 · Cited by 206 · see citing works
Developmental Origins of Health and Disease
Rass, E. (2017) · Routledge eBooks · doi:10.4324/9781315445564-6 · Cited by 200 · see citing works
Gamborg, M., Byberg, L., Rasmussen, F. E., Andersen, P. K., Baker, J. L., Bengtsson, C., Canoy, D., Drøyvold, W. B., Eriksson, J. G., Forsén, T., et al. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm042 · Cited by 186 · see citing works
Bellinger, L., Sculley, D. V., & Langley-Evans, S. C. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803205 · Cited by 183 · see citing works
Self-citationGilbert, J. S., Lang, A. L., Grant, A. R., & Nijland, M. J. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.084202 · Cited by 183 · see citing works
Nuyt, A. M. (2007) · Clinical Science · doi:10.1042/cs20070113 · Cited by 178 · see citing works
Rosario, F. J., Jansson, N., Kanai, Y., Prasad, P. D., Powell, T. L., & Jansson, T. (2011) · Endocrinology · doi:10.1210/en.2010-1153 · Cited by 176 · see citing works
Cambonie, G., Comte, B., Yzydorczyk, C., Ntimbane, T., Germain, N., Lê, N. L. O., Pladys, P., Gauthier, C., Lahaie, I., Abran, D., et al. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00227.2006 · Cited by 171 · see citing works
Harrison, M., & Langley-Evans, S. (2008) · British Journal of Nutrition · doi:10.1017/s0007114508057607 · Cited by 175 · see citing works
Self-citationPorcine models for the metabolic syndrome, digestive and bone disorders: a general overview
Litten-Brown, J. C., Corson, A. M., & Clarke, L. (2010) · animal · doi:10.1017/s1751731110000200 · Cited by 165 · see citing works
Early programming of adult diseases in resource poor countries
Prentice, A. M. (2005) · Archives of Disease in Childhood · doi:10.1136/adc.2004.059030 · Cited by 164 · see citing works
Regulation of placental nutrient transport and implications for fetal growth
Bell, A. W., & Ehrhardt, R. (2002) · Nutrition Research Reviews · doi:10.1079/nrr200239 · Cited by 161 · see citing works
Sex differences in the developmental origins of hypertension and cardiorenal disease
Gilbert, J. S., & Nijland, M. J. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90724.2008 · Cited by 159 · see citing works
Maternal low-protein diet in rat pregnancy programs blood pressure through sex-specific mechanisms
McMullen, S., & Langley‐Evans, S. C. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00435.2004 · Cited by 158 · see citing works
Self-citationTimescales of Human Adaptation: The Role of Epigenetic Processes
Kuzawa, C. W., & Thayer, Z. M. (2011) · Epigenomics · doi:10.2217/epi.11.11 · Cited by 149 · see citing works
Gardner, D. S., Pearce, S., Dandrea, J., Walker, R., Ramsay, M., Stephenson, T. J., & Symonds, M. E. (2004) · Hypertension · doi:10.1161/01.hyp.0000126991.67203.7b · Cited by 151 · see citing works
Angiotensin II receptors and drug discovery in cardiovascular disease
Dasgupta, C., & Zhang, L. (2010) · Drug Discovery Today · doi:10.1016/j.drudis.2010.11.016 · Cited by 150 · see citing works
Lin, M., & Liu, E. M. (2014) · Journal of Health Economics · doi:10.1016/j.jhealeco.2014.05.004 · Cited by 141 · see citing works
Maternal stress and fetal responses: Evolutionary perspectives on preterm delivery
Pike, I. L. (2004) · American Journal of Human Biology · doi:10.1002/ajhb.20093 · Cited by 139 · see citing works
Evidence for sympathetic origins of hypertension in juvenile offspring of obese rats
Samuelsson, A.-M., Morris, A., Igosheva, N., Kirk, S. L., Pombo, J. M. C., Coen, C. W., Poston, L., & Taylor, P. D. (2010) · Hypertension · doi:10.1161/hypertensionaha.109.139402 · Cited by 138 · see citing works
Programming of adult cardiovascular function after early maternal undernutrition in sheep
Gopalakrishnan, G. S., Gardner, D. S., Rhind, S. M., Rae, M. T., Kyle, C. E., Brooks, A. N., Walker, R. M., Ramsay, M., Keisler, D. H., Stephenson, T. J., et al. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00687.2003 · Cited by 134 · see citing works
Embryonic and fetal programming of physiological disorders in adulthood
Lau, C. S., & Rogers, J. M. (2004) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.20029 · Cited by 134 · see citing works
Karrow, N. A. (2005) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2005.05.003 · Cited by 132 · see citing works
Animal models of programming: early life influences on appetite and feeding behaviour
Langley‐Evans, S. C., Bellinger, L., & McMullen, S. (2005) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2005.00015.x · Cited by 126 · see citing works
Self-citationHoppe, C. C., Evans, R. G., Moritz, K. M., Cullen‐McEwen, L. A., Fitzgerald, S. M., Dowling, J. P., & Bertram, J. F. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00079.2006 · Cited by 125 · see citing works
Prenatal programming of angiotensin II type 2 receptor expression in the rat
McMullen, S., Gardner, D. S., & Langley‐Evans, S. C. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20031029 · Cited by 116 · see citing works
Self-citationIn UteroProgramming of Later Adiposity: The Role of Fetal Growth Restriction
Sarr, O., Yang, K., & Regnault, T. R. H. (2012) · Journal of Pregnancy · doi:10.1155/2012/134758 · Cited by 106 · see citing works
Islet cell response in the neonatal rat after exposure to a high-fat diet during pregnancy
Cerf, M. E., Williams, K. G., Nkomo, X. I., Muller, C. J. F., Toit, D. F. D., Louw, J., & Wolfe‐Coote, S. A. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00335.2004 · Cited by 107 · see citing works
Thompson, J. G., Kind, K. L., Roberts, C. T., Robertson, S. A., & Robinson, J. S. (2002) · Human Reproduction · doi:10.1093/humrep/17.11.2783 · Cited by 106 · see citing works
Campión, J., Milagro, F. I., & Martínez, J. A. (2010) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-375003-7.00011-x · Cited by 104 · see citing works
Gopalakrishnan, G. S., Gardner, D. S., Dandrea, J., Langley‐Evans, S. C., Pearce, S., Kurlak, L. O., Walker, R. M., Seetho, I. W., Keisler, D. H., Ramsay, M., et al. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20051559 · Cited by 104 · see citing works
Self-citationDEVELOPMENTAL DETERMINANTS OF BLOOD PRESSURE IN ADULTS
Adair, L. S., & Dahly, D. L. (2005) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.25.050304.092538 · Cited by 101 · see citing works
Intrauterine Growth Restriction: Fetal Programming of Hypertension and Kidney Disease
Ojeda, N. B., Grigore, D., & Alexander, B. T. (2008) · Advances in Chronic Kidney Disease · doi:10.1053/j.ackd.2008.01.001 · Cited by 101 · see citing works
Mastorci, F., Vicentini, M., Viltart, O., Manghi, M., Graiani, G., Quaini, F., Meerlo, P., Nalivaiko, E., Maccari, S., & Sgoifo, A. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.08.001 · Cited by 99 · see citing works
Impact of Prenatal Stress on Neuroendocrine Programming
Viltart, O., & Vanbesien-Mailliot, C. (2007) · The Scientific World JOURNAL · doi:10.1100/tsw.2007.204 · Cited by 86 · see citing works
Fetal programming of appetite by exposure to a maternal low-protein diet in the rat
Bellinger, L., & Langley‐Evans, S. C. (2005) · Clinical Science · doi:10.1042/cs20050127 · Cited by 84 · see citing works
Self-citationDiet during pregnancy, neonatal outcomes and later health
Moore, V., & Davies, M. J. (2005) · Reproduction Fertility and Development · doi:10.1071/rd04094 · Cited by 82 · see citing works
Fleming, T. P., Watkins, A. J., Sun, C., Velazquez, M. A., Smyth, N. R., & Eckert, J. J. (2015) · Reproduction Fertility and Development · doi:10.1071/rd14455 · Cited by 83 · see citing works
Perinatal protein restriction reduces the inhibitory action of serotonin on food intake
de Souza, S. L., Orozco-Solís, R., Grit, I., Manhães‐de‐Castro, R., & Bolaños, F. J. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06105.x · Cited by 80 · see citing works
Racasan, S., Braam, B. G., Koomans, H. A., & Joles, J. A. (2004) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00314.2004 · Cited by 74 · see citing works
A Critical Evaluation of the Fetal Origins Hypothesis and Its Implications for Developing Countries
Adair, L. S., & Prentice, A. M. (2004) · Journal of Nutrition · doi:10.1093/jn/134.1.191 · Cited by 68 · see citing works
Pimentel, G. D., Lira, F. S., Neto, J. C. R., de Oliveira, J. L., Hachul, A. C. L., Souza, G. I. H., do Carmo, M. D. G. T., dos Santos, R. V. T., de Mello, M. T., Tufik, S., et al. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.12.003 · Cited by 68 · see citing works
Programmed hypertension: kidney, brain or both?
Dodic, M., Moritz, K. M., Koukoulas, I., & Wintour, E. M. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00693-8 · Cited by 67 · see citing works
Maternal Corticotropin‐Releasing Hormone Levels during Pregnancy and Offspring Adiposity
Gillman, M. W., Rich‐Edwards, J. W., Huh, S., Majzoub, J. A., Oken, E., Taveras, E. M., & Rifas‐Shiman, S. L. (2006) · Obesity · doi:10.1038/oby.2006.189 · Cited by 66 · see citing works
Programming of cardiovascular disease across the life-course
Blackmore, H. L., & Ozanne, S. E. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.12.006 · Cited by 65 · see citing works
Blastocyst environment and its influence on offspring cardiovascular health: the heart of the matter
Watkins, A. J., & Fleming, T. P. (2009) · Journal of Anatomy · doi:10.1111/j.1469-7580.2008.01033.x · Cited by 64 · see citing works
Managing the Prenatal Environment to Enhance Livestock Productivity
Greenwood, P. L., Bell, A. W., Vercoe, P. E., & Viljoen, G. J. (2009) · Springer eBooks · doi:10.1007/978-90-481-3135-8 · Cited by 63 · see citing works
Hogg, K., McNeilly, A. S., & Duncan, W. C. (2011) · Endocrinology · doi:10.1210/en.2010-1219 · Cited by 62 · see citing works
Mitra, A., Alvers, K. M., Crump, E. M., & Rowland, N. E. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90553.2008 · Cited by 61 · see citing works
Langley-Evans, A. J., & Langley‐Evans, S. C. (2003) · The Journal of the Royal Society for the Promotion of Health · doi:10.1177/146642400312300409 · Cited by 60 · see citing works
Self-citationBudge, H., Edwards, L. J., McMillen, I. C., Bryce, A., Warnes, K., Pearce, S., Stephenson, T., & Symonds, M. E. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.018986 · Cited by 59 · see citing works
Programming of hepatic antioxidant capacity and oxidative injury in the ageing rat
Langley‐Evans, S. C., & Sculley, D. (2005) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2005.03.003 · Cited by 57 · see citing works
Self-citationHeywood, W., Mian, N., Milla, P. J., & Lindley, K. J. (2004) · Clinical Science · doi:10.1042/cs20030350 · Cited by 56 · see citing works
Yzydorczyk, C., Gobeil, F., Cambonie, G., Lahaie, I., Lê, N. L. O., Samarani, S., Ahmad, A., Lavoie, J., Oligny, L. L., Pladys, P., et al. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00798.2005 · Cited by 55 · see citing works
Kuneš, J., & Zicha, J. (2006) · Clinical Science · doi:10.1042/cs20050271 · Cited by 53 · see citing works
Postnatal fluoxetine treatment affects the development of serotonergic neurons in rats
da Silva, C. M., Gonçalves, L., Manhães‐de‐Castro, R., & Nogueira, M. I. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.08.003 · Cited by 49 · see citing works
Rumball, C. W. H., Bloomfield, F. H., Oliver, M. H., & Harding, J. E. (2009) · Pediatric Research · doi:10.1203/pdr.0b013e3181bbde72 · Cited by 48 · see citing works
Morisaki, N., Nagata, C., Yasuo, S., Morokuma, S., Kato, K., Sanefuji, M., Shibata, E., Tsuji, M., Senju, A., Kawamoto, T., et al. (2018) · British Journal Of Nutrition · doi:10.1017/s000711451800291x · Cited by 46 · see citing works
Maternal hypomagnesemia causes placental abnormalities and fetal and postnatal mortality
Schlegel, R., Cuffe, J. S. M., Moritz, K. M., & Paravicini, T. M. (2015) · Placenta · doi:10.1016/j.placenta.2015.03.011 · Cited by 43 · see citing works
Epigenetic inheritance of metabolic state
Palu, R. A. S., & Thummel, C. S. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.03.008 · Cited by 43 · see citing works
Buffat, C., Mondon, F., Rigourd, V., Boubred, F., Bessières, B., Fayol, L., Feuerstein, J. M., GAMERRE, M., Jammes, H., Rebourcet, R., et al. (2007) · The Journal of Pathology · doi:10.1002/path.2233 · Cited by 43 · see citing works
Chuang, T., Pearce, W. J., & Khorram, O. (2015) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00254.2014 · Cited by 42 · see citing works
Metges, C. C., Lang, I. S., Hennig, U., Brüssow, K. ‐., Kanitz, E., Tuchscherer, M., Schneider, F., Weitzel, J. M., Steinhoff-Ooster, A., Sauerwein, H., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031390 · Cited by 42 · see citing works
Segar, J. L., Roghair, R. D., Segar, E. M., Bailey, M. C., SCHOLZ, T. D., & Lamb, F. S. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00677.2005 · Cited by 42 · see citing works
Kuzawa, C. W., & Pike, I. L. (2004) · American Journal of Human Biology · doi:10.1002/ajhb.20090 · Cited by 42 · see citing works
Nutritional programming of adult disease
Buckley, A. J., Jaquiery, A. L., & Harding, J. E. (2005) · Cell and Tissue Research · doi:10.1007/s00441-005-1095-7 · Cited by 38 · see citing works
Bai, S. Y., Briggs, D. I., & Vickers, M. H. (2012) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174412000256 · Cited by 37 · see citing works
Dodic, M., McAlinden, A. T., Jefferies, A. J., Wintour, E. M., Cock, M. L., May, C. N., Evans, R. G., & Moritz, K. M. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2005.102186 · Cited by 37 · see citing works
Exploring the health status of older persons in Sub-Saharan Africa
Audain, K. A., Carr, M., Dikmen, D., Zotor, F. B., & Ellahi, B. (2017) · Proceedings of The Nutrition Society · doi:10.1017/s0029665117000398 · Cited by 34 · see citing works
McDade, T. W., Kuzawa, C. W., Adair, L. S., & Beck, M. A. (2004) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2004.01834.x · Cited by 34 · see citing works
Mammalian Development in Space
Ronca, A. E. (2003) · Advances in space biology and medicine · doi:10.1016/s1569-2574(03)09009-9 · Cited by 34 · see citing works
Kuzawa, C. W. (2004) · Journal of Nutrition · doi:10.1093/jn/134.1.194 · Cited by 32 · see citing works
Does Early Mismatched Nutrition Predispose to Hypertension and Atherosclerosis, in Male Mice?
Bol, V., Desjardins, F., Reusens, B., Balligand, J., & Remacle, C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012656 · Cited by 30 · see citing works
Symonds, M. E., Gopalakrishnan, G. S., Bispham, J., Pearce, S., Dandrea, J., Mostyn, A., Ramsay, M., & Stephenson, T. J. (2003) · Archives of Physiology and Biochemistry · doi:10.1076/apab.111.1.45.15141 · Cited by 29 · see citing works
Niedhammer, I., Murrin, C. M., O'Mahony, D., Daly, S., Morrison, J., Kelleher, C. C., & the Lifeways Cross-Generation Cohort Study Steering Group (2011) · European Journal of Public Health · doi:10.1093/eurpub/ckr089 · Cited by 27 · see citing works
Calvert, J. W., Lefer, D. J., Gundewar, S., Poston, L., & Coetzee, W. A. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.047183 · Cited by 28 · see citing works
Mechanisms involved in the reduced leukocyte migration in intrauterine undernourishment
Landgraf, M. A., Tostes, R. C., Borelli, P., Zorn, T. M. T., Nigro, D., de Carvalho, M. H. C., & Fortes, Z. B. (2006) · Nutrition · doi:10.1016/j.nut.2006.08.020 · Cited by 28 · see citing works
Parental obesity leads to metabolic changes in the F2 generation in Drosophila
Palu, R. A. S., Praggastis, S. A., & Thummel, C. S. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.03.012 · Cited by 28 · see citing works
Impact and mechanisms of fetal physiological programming
Schwartz, J., & Morrison, J. L. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00698.2004 · Cited by 28 · see citing works
Erhuma, A. M., McMullen, S., Langley‐Evans, S. C., & Bennett, A. J. (2009) · Endocrine · doi:10.1007/s12020-009-9225-8 · Cited by 27 · see citing works
Self-citationFetal developmental programing: insights from human studies and experimental models
Lopes, G. A. D., Ribeiro, V. L. B., Barbisan, L. F., & Rodrigues, M. A. M. (2016) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2016.1183635 · Cited by 25 · see citing works
Chapter 1 Regulation of metabolism and growth during prenatal life
Bell, A. W., Greenwood, P. L., & Ehrhardt, R. (2005) · Biology of growing animals · doi:10.1016/s1877-1823(09)70008-6 · Cited by 25 · see citing works
Manojlović-Stojanoski, M., Nestorović, N., Negić, N., Filipović, B., Sosić-Jurjević, B., Sekulić, M., & Milosević, V. (2007) · PubMed · Cited by 24 · see citing works
Jahan-Mihan, A., Szeto, I. M. Y., Luhovyy, B. L., Huot, P. S. P., & Anderson, G. H. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511002686 · Cited by 24 · see citing works
Jahan-Mihan, A., Smith, C. E., & Anderson, G. H. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00744.2010 · Cited by 24 · see citing works
Langley‐Evans, S. C., Lilley, C., & McMullen, S. (2006) · British Journal Of Nutrition · doi:10.1079/bjn20061822 · Cited by 23 · see citing works
Self-citationHuman embryonic stem cells as a model for nutritional programming: An evaluation
Allegrucci, C., Denning, C. N., Burridge, P. W., Steele, W., Sinclair, K. D., & Young, L. E. (2005) · Reproductive Toxicology · doi:10.1016/j.reprotox.2005.04.010 · Cited by 23 · see citing works
Khanal, P., Axel, A. M. D., Kongsted, A. H., Husted, S., Johnsen, L., Pandey, D., Pedersen, K., Birtwistle, M., Markussen, B., Kadarmideen, H. N., et al. (2014) · Acta Physiologica · doi:10.1111/apha.12391 · Cited by 21 · see citing works
Durrant, L. M., Khorram, O., Buchholz, J. N., & Pearce, W. J. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00436.2013 · Cited by 21 · see citing works
- Authors
- Langley-Evans, S. C.
- Venue
- Proceedings of the Nutrition Society
- Publisher
- Cambridge University Press (CUP)
- Published
- 2001-11
- Volume
- 60
- Issue
- 4
- Pages
- 505-513
- ISSN
- 0029-6651 (ISSN-L)
- 1475-2719
- OpenAlex
- W2135897417
- Cited by
- 203
- References
- 94
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 5 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 4 · 2017: 3 · 2016: 6 · 2015: 6 · 2014: 15 · 2013: 9 · 2012: 6
- FWCI
- 2.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of The Nutrition Society (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- fetal programming, maternal undernutrition, cardiovascular risk, low birth weight, fetal growth restriction, prenatal nutrition, low-protein diet, hypertension, glucocorticoids, hypothalamic-pituitary-adrenal axis, renin-angiotensin system, vascular resistance
- MeSH terms
- Animals, Birth Weight, Cardiovascular Diseases, Disease Models, Animal, Female, Glucocorticoids, Humans, Hypertension, Kidney, Nutrition Disorders, Pregnancy, Pregnancy Complications, Prenatal Exposure Delayed Effects, Renin-Angiotensin System, Risk Factors, Rats
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