Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals

Chromatin modifications and their function

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Cell Signaling by Receptor Tyrosine Kinases

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The Epigenomics of Cancer

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TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

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Cell Signaling by Receptor Tyrosine Kinases

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High Frequency of Mutations of the PIK3CA Gene in Human Cancers

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Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas

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FOXM1 transcriptional regulation

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Inhibitory Effect of Tangeretin and Cardamonin on Human Intestinal SGLT1 Activity In Vitro and Blood Glucose Levels in Mice In Vivo

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Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways

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Xanthohumol and the Medicinal Benefits of Beer

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Metal‐Free trans‐Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone

Gopalan, G., Dhanya, B. P., Saranya, J., Reshmitha, T. R., Baiju, T. V., Meenu, M. T., Nair, M. S., Nisha, P., & Radhakrishnan, K. V. (2017) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201700410 · Cited by 16

Chemoprevention of Gastrointestinal Cancer: The Reality and the Dream

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Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational association

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Antimicrobial activity of the crude extract, fractions and isolation of zerumbone from the rhizomes of Zingiber roseum

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Combinatorial effect of thymoquinone with chemo agents for tumor therapy

Jehan, S., Huang, J., Farooq, U., Basheer, I., & Zhou, W. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.153936 · Cited by 13

Capsaicin, an active ingredient from chilli peppers, attenuates glycative stress and restores sRAGE levels in diabetic rats

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A network pharmacology approach to investigate the pharmacological effect of curcumin and capsaicin targets in cancer angiogenesis by module-based PPI network analysis

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Anticancer, Antioxidant and Antiangiogenic Activities of Nanoparticles of Bioactive Dietary Nutraceuticals

Bansode, P. A., Patil, P. V., Birajdar, A., Somasundaram, I., Bachute, M. T., & Rashinkar, G. S. (2019) · ChemistrySelect · doi:10.1002/slct.201903946 · Cited by 13

Antitumor potential of anethole singly and in combination with cyclophosphamide in murine Sarcoma-180 transplantable tumor model

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Plant Natural Products as Neuroprotective Nutraceuticals: Preclinical and Clinical Studies and Future Implications

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Molecular Action of Herbal Antioxidants in Regulation of Cancer Growth: Scope for Novel Anticancer Drugs

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Curcumin restores glutathione-S-transferase activity for LNCaP prostate cancer cells

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Synthesis and in vitro evaluation of zerumbone pendant derivatives: potent candidates for anti-diabetic and anti-proliferative activities

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Improving bioavailability of nutraceuticals by nanoemulsification

Pund, S., Joshi, A., & Patravale, V. B. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804305-9.00013-0 · Cited by 11

Combination of Chemopreventive Agents in Nanoparticles for Cancer Prevention

Yang, C. S., Wang, H., & Hu, B. (2013) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-13-0312 · Cited by 10

Molecular Targeted Therapies Using Botanicals for Prostate Cancer Chemoprevention

Kumar, N. B. (2013) · Translational Medicine · doi:10.4172/2161-1025.s2-005 · Cited by 10

Assessment of Secondary Metabolites with Different Uses of Fenugreek

Yaldız, G., & Çamlıca, M. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.99479 · Cited by 10

Role of Gambogic Acid in Chemosensitization of Cancer

Kale, V. P., Gilhooley, P. J., Phadtare, S., Nabavizadeh, A., & Pandey, M. K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812373-7.00008-5 · Cited by 10

RNA-seq data analysis of stimulated hepatocellular carcinoma cells treated with epigallocatechin gallate and fisetin reveals target genes and action mechanisms

Agioutantis, P. C., Kotsikoris, V., Kolisis, F. N., & Loutrari, H. V. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.03.006 · Cited by 10

In-vitro analysis of selective nutraceuticals binding to human transcription factors through computer aided molecular docking predictions

Teimouri, M., Junaid, M., Saleem, S., Khan, A., & Ali, A. (2016) · Bioinformation · doi:10.6026/97320630012354 · Cited by 10

Bioactives from Culinary Spices and Herbs: A Review

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Genome-Based Multi-targeting of Cancer: Hype or Hope?

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Plant molecules and their influence on health and female reproduction

Sirotkin, A. V., & Kolesárová, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824292-6.00004-0 · Cited by 10

Synthetic polyploidy in spice crops: A review

George, N. M., Aswathi, A. P., & Prasath, D. (2023) · Crop Science · doi:10.1002/csc2.21134 · Cited by 8

Comparative study: Garlic, ginger and turmeric as natural antimicrobials and bioactives

Oyinlola, K. A., Ogunleye, G. E., Balogun, A. I., & Joseph, O. J. (2024) · South African Journal of Science · doi:10.17159/sajs.2024/14170 · Cited by 8

Thermal Processing of Herbs and Spices

Kurup, A. H., Deotale, S. M., Rawson, A., & Patras, A. (2020) · doi:10.1002/9781119036685.ch1 · Cited by 8

Experimental Research on the In Vitro Antitumor Effects of Crataegus sanguinea

Sun, J., Gao, G., Gao, Y., Xiong, L., Li, X., Guo, J., & Zhang, Y. (2013) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-013-9535-6 · Cited by 7

Green chemistry approach to the synthesis of zinc nanoparticles using Cyperus rotundus rhizome extract for the treatment of lung well-differentiated bronchogenic adenocarcinoma

Zhao, Z., Liu, G., Lin, Y., & Wang, L. (2022) · Journal of Experimental Nanoscience · doi:10.1080/17458080.2022.2120194 · Cited by 6

Bioactive compounds in functional fruits and vegetables: A strategy for promoting wellness and preventing diseases

Moreira, M. R., & Ponce, A. G. (2024) · Studies in natural products chemistry · doi:10.1016/b978-0-443-15756-1.00012-4 · Cited by 6

Bioavailability, pharmacokinetic, pharmacodynamic, and clinical studies of natural products on their antiinflammatory activities

Nair, A., Gopi, S., & Jacob, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819218-4.00006-7 · Cited by 6

Oxidative stress and cancer: Antioxidative role of Ayurvedic plants

Prasad, S., & Srivastava, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819547-5.00027-4 · Cited by 6

New electroanalytical method for the determination of trans-anethole in spices and sweets

Jashari, G., Frühbauerová, M., Mikýsek, T., Švancara, I., Metelka, R., & Sýs, M. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.135167 · Cited by 6

Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model

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Potential Therapeutic Impacts of Curcumin for Improving Memory Impairment

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Cancer Therapy

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Traditional Medicinal Plants in Cancer Therapy and Chemoprevention: A Review of Preclinical and Clinical Studies

Sidhic, J., George, S., & Narayanankutty, A. (2023) · Current Nutrition & Food Science · doi:10.2174/1573401319666230816141305 · Cited by 5

Target identification and polypharmacology of nutraceuticals

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Nutraceuticals Derived from Dietary Spices as Candidate Molecules in Targeting Glioma Signaling Pathways

Rani, V., Pavan, S. R., & Prabhu, A. (2022) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-022-00285-3 · Cited by 5

Huile essentielle de Clou de girofle

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Natural Products for Cancer Prevention and Therapy

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Effects of Curcumin Supplementation on Viability and Antioxidant Capacity of Buffalo Granulosa Cells under In Vitro Culture Conditions

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Inhibitor Effect of Antioxidant Flavonoids Quercitin, and Capsaicin in Mast Cell Inflammation

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A Review on the Potential Effects of Curcumin in the Treatment of Neuroblastoma and its Underlying Mechanisms

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Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma

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Green formulation and characterization of Fe nanoparticles containing Calendula extract and investigation of the antioxidant, cytotoxicity and anti-human cholangiocarcinoma properties

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Redox Status and Aging Link in Neurodegenerative Diseases 2015

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Health-Promoting Effects of Cardamom (Elettaria cardamomum)

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Sunlight-Induced Skin Cancer in Companion Animals

Saavedra, P. V., & Kitchell, B. E. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7357-2_33 · Cited by 3

Heterocyclic Anti-cancer Compounds Derived from Natural Sources with their Mechanism of Action

Bachar, S. C., Kadir, A. K. M. S., Wahab, R., & Hasan, A. A. (2022) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815040074122010004 · Cited by 3

Natural Anticarcinogens: The Efficacy of Herbs and Spices

Vikas, B., Sweety, V. K., Anil, S., & Palaniyandi, S. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1004335 · Cited by 3

Studies Studies on the phytochemicals of clove and their biological activities

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Proceedings of the I ndo‐ U.S. bilateral workshop on accelerating botanicals/biologics agent development research for cancer chemoprevention, treatment, and survival

Kumar, N. B., Dhurandhar, M., Aggarwal, B. B., Anant, S., Daniel, K. G., Deng, G., Djeu, J. Y., Dou, J., Hawk, E. T., Jayaram, B., et al. (2012) · Cancer Medicine · doi:10.1002/cam4.42 · Cited by 2

Cellular Stress Response, Hormesis, and Vitagens in Aging and Longevity

Cornelius, C., Graziano, A., Perrotta, R. E., Paola, R. D., Cuzzocrea, S., Calabrese, E. J., & Calabrese, V. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397803-5.00026-5 · Cited by 2

Delivery of curcuminoids by buttermilk

Fu, S. (2015) · Minerva Access (University of Melbourne) · Cited by 2

Assessment and Evaluation of the Antibacterial Activity of Essential Oils of Capsicum annuum, Monodora myristica and Ocimum canum Seeds on Staphylococcus aureus, Bacillus cereus, Escherichia coli and Salmonella typhimurium

Nnanyelugo, B., Christian, O., Onyebuchi Federick, O., Lauretta, E., Ebeke, O. O., & Okoro, O. I. (2022) · Journal of Applied Sciences · doi:10.3923/jas.2022.180.186 · Cited by 2

DIOSGENIN AT THE CELLULAR LEVEL AS A CANCER REMEDIAL AGENT

Arockiam, A. J. V., Ganesan, N., & Umapathy, D. (2023) · INDIAN DRUGS · doi:10.53879/id.60.04.11812 · Cited by 1

Spices and Herbs as Food Preservatives

Vijayan, A., & Shyni, K. (2024) · FoodSci Indian Journal of Research in Food Science and Nutrition · doi:10.15613/fijrfn/2024/v11i1/44793 · Cited by 1

Determination of the Interleukin‐8 Inhibitory Properties of Naringin and Hesperidin Compounds by Molecular Dynamics

Alshahrani, M. Y., Alkhathami, A. G., Alshehri, S. A., Wahab, S., Nasir, N., Atif, S. A., Alshaikh, A., & Chandra, S. (2025) · ChemistrySelect · doi:10.1002/slct.202404718 · Cited by 1

Plant Extracts from Origanum vulgare and Vaccinium macrocarpon Induce Apoptosis of Bone Metastasized Breast Cancer Cells in a 3D Bone-Mimetic Testbed of Bone Metastasis

Ravi, P., Jasuja, H., Sarkar, D., Katti, D. R., Shetty, K., & Katti, K. S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27052355 · Cited by 1

Dose-Dependent Effects of Clove Oil on Human Nasal Epithelial Cells In Vitro

Kesimli, M. C., Muluk, N. B., Kurt, A., Keskin, S. U., Bülbül, M. V., Alaskarov, E., & Cingi, C. (2026) · Journal of Craniofacial Surgery · doi:10.1097/scs.0000000000012617 · Cited by 1

Challenges in Multiple Myeloma Chemoprevention: Potential Role of Natural, Synthetic and Endogenous Molecules

Amodio, N., Morelli, E., Barone, A., & Tassone, P. (2016) · Springer eBooks · doi:10.1007/978-3-319-31254-5_3 · Cited by 1

The cytotoxic potential for Syzygium aromaticum and Nigella sativa essential oil compared to doxorubicin against pancreatic, colonic, and cervical cancer cell lines.

Ali, M. M., Ahmed, H., El-baset, S. A. A., & Bakry, S. (2023) · Egyptian Journal of Chemistry · doi:10.21608/ejchem.2023.214774.8083 · Cited by 1

Interaction of Dietary Metabolites with Anticancer Drug Targets

Gacche, R. N. (2021) · Springer eBooks · doi:10.1007/978-981-16-6050-4_10 · Cited by 1

Evaluation of the Effects of Walnut Extract on the Cell Division G2/M Cyclin-Cyclin B1 in Breast Cancer Cells

Shah, S. P. (2016) · San José State University ScholarWorks (San Jose State University) · doi:10.31979/etd.32pr-8xtr · Cited by 2

Curcumina: de especiaria à nutracêutico

Collino, L. (2014) · Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)

Green Tea Catechins for Prostate Cancer Chemoprevention

Chornokur, G., & Kumar, N. B. (2015) · InTech eBooks · doi:10.5772/59872

Inhibition of Pancreatitis and Carcinogenesis by Capsaicin

Zhang, W., Liao, J., Li, H., Yang, A. L., Srivastava, S., & Yang, G. (2013) · Springer eBooks · doi:10.1007/978-94-007-6317-3_5

Molecular Targeted Therapies Using Botanicals for Prostate Cancer

Lee, H. (2012)

Anti-Proliferative and Pro-Apoptotic Effects of Bioactive Constituents Derived from Fruits and Vegetables Against Colorectal Cancer

Sikka, S., & Sethi, G. (2015) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789814508896_0004

PHYTOTHERAPIES

McLachlan, A. J., & Clarke, S. J. (2015) · Wiley eBooks · doi:10.1002/9781119006039.ch21

Role of anti-inflammatory agents in the treatment of lymphoma

Pandey, M. K., & Aggarwal, B. B. (2015) · doi:10.2217/fmeb2014.14.30

Nutritional Support After Surgery of the Liver

Memeo, R., & D’Eugenio, A. (2019) · Springer eBooks · doi:10.1007/978-3-030-16554-3_8

Evaluation of the Therapeutic Effect of Syzygium aromaticum Essential Oil in Wistar Rats Infected with Candida albicans - Biochemical and Hematological Study

Adli, D. E. H., Kahloula, K., Kourat, D., Brahmi, M., Souidi, S. W., Naar, A., & Slimani, M. (2021) · Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Veterinary Medicine · doi:10.15835/buasvmcn-vm:2020.0048

Role of traditional medicines in the management of cancer

Mohammed Husain, G., & Abdul Waheed, M. (2014) · Journal of Medical and Scientific Research · doi:10.17727/jmsr.2014/2-038

COMPROMETIMENTO DO ESTADO NUTRICIONAL NA DOENÇA RENAL CRÔNICA

Bellafronte, N. T., & Chiarello, P. G. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220105229

Zingiber officinale COMO ADJUVANTE DO TRATAMENTO QUIMIOTERÁPICO EM PACIENTES COM CÂNCER: ENSAIO CLÍNICO RANDOMIZADO, DUPLO CEGO, PLACEBO CONTROLADO

Barreto, A. M. C., Souza, B. D. A. T., & Fortes, R. C. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220105291

ALIMENTAÇÃO, ESTILO DE VIDA E ROTINA DE TRATAMENTO E CUIDADOS DE PACIENTES COM CÂNCER DURANTE A PANDEMIA: UMA REVISÃO DE LITERATURA

Cardoso, I. G., de Andrade, R. M. S., & Ferreira, C. C. D. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220105252

Efeitos da ingestão de cogumelos Pleurotus ostreatus enriquecidos sobre as variáveis bioquímicas de ratos wistar

Junior, N., & Oliveira, M. G. D. A. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220205300

MALEFÍCIOS DO LEITE DE VACA

Gonçalves, N. E. X. M. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220105247

Nutrição em foco: uma abordagem holística

(2021) · Editora Conhecimento Livre eBooks · doi:10.37423/2021.edcl406

ASSISTÊNCIA NUTRICIONAL A PACIENTES ONCOLÓGICOS AMBULATORIAIS EM TEMPOS DE PANDEMIA: RELATO DE EXPERIÊNCIA

Lyra, S. L., Fontenele, C. M., Gomes, C. B. S., Guerreiro, K. D. A., & de Lima, V. C. S. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220105237

TERAPIA NUTRICIONAL E CORONAVÍRUS EM PACIENTES ONCOLÓGICOS: REVISÃO DE LITERATURA

Feio, C. B., & Estrela, R. V. D. F. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/220105226

Eugenol-based nutraceuticals

Taleuzzaman, M., Verma, R., & Farhana, J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85177-0.00025-2

Sunscreens: Toxic Effects as Determined by Biomarkers

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