Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals

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Thymoquinone and quercetin induce enhanced apoptosis in non‐small cell lung cancer in combination through the Bax/Bcl2 cascade

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Cytotoxic Half-Sandwich Rh(III) and Ir(III) β-Diketonates

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Curcumin Reduces Cytotoxicity of 5-Fluorouracil Treatment in Human Breast Cancer Cells

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Molecular Targets of Naturopathy in Cancer Research: Bridge to Modern Medicine

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Capsaicin inhibits cell proliferation by cytochrome c release in gastric cancer cells

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The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells

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Stimulating the proliferation, migration and lamellipodia of Schwann cells using low-dose curcumin

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Curcumin: The Golden Nutraceutical on the Road to Cancer Prevention and Therapeutics. A Clinical Perspective

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The Healing Effects of Spices in Chronic Diseases

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Diosgenin and Its Fenugreek Based Biological Matrix Affect Insulin Resistance and Anabolic Hormones in a Rat Based Insulin Resistance Model

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Cardamonin Attenuates Experimental Colitis and Associated Colorectal Cancer

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Clove essential oil confers antioxidant activity and lifespan extension in C. elegans via the DAF-16/FOXO transcription factor

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Hydroxychavicol, a polyphenol from Piper betle leaf extract, induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells

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Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways

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Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells

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Diosgenin Suppresses Cholangiocarcinoma Cells Via Inducing Cell Cycle Arrest And Mitochondria-Mediated Apoptosis

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Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates

Badr-Eldin, S. M., Alhakamy, N. A., Fahmy, U. A., Ahmed, O. A. A., Asfour, H. Z., Althagafi, A. A., Aldawsari, H. M., Rizg, W. Y., Mahdi, W. A., Alghaith, A. F., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.642171 · Cited by 29

Chemopreventive Potential of Dietary Nanonutraceuticals for Prostate Cancer: An Extensive Review

Chopra, H., Bibi, S., Goyal, R., Gautam, R. K., Trivedi, R., Upadhyay, T. K., Mujahid, M. H., Shah, M. A., Haris, M., Khot, K. B., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.925379 · Cited by 29

Achillea fragrantissima extract exerts its anticancer effect via induction of differentiation, cell cycle arrest and apoptosis in chronic myeloid leukemia (CML) cell line K562

Alenad, A. M., Al‐Jaber, N. A., Krishnaswamy, S., Yakout, S. M., Al‐Daghri, N. M., & Alokail, M. S. (2013) · Journal of Medicinal Plants Research · doi:10.5897/jmpr.9000036 · Cited by 27

Beyond the flavour: a de-flavoured polyphenol rich extract of clove buds (Syzygium aromaticum L) as a novel dietary antioxidant ingredient

Johannah, N. M., Mammen, R. R., Gopakumar, G., Maliakel, B. P., Sureshkumar, D., & Krishnakumar, I. M. (2015) · Food & Function · doi:10.1039/c5fo00682a · Cited by 27

6‐shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines

Kotowski, U., Kadletz, L., Schneider, S., Foki, E., Schmid, R. W., Seemann, R., Thurnher, D., & Heiduschka, G. (2017) · Phytotherapy Research · doi:10.1002/ptr.5982 · Cited by 26

Exploring the Therapeutic Potential of Bioactive Compounds from Plant Sources

Chintada, V., & Golla, N. (2025) · Sustainable landscape planning and natural resources management · doi:10.1007/978-3-031-76859-0_15 · Cited by 38

Exploring the anti-colon cancer potential of febuxostat-based mixed metal complexes with 2,2′-bipyridine: MTT assay, toxicity evaluation, prediction profiles, and computational studies

Abbass, L. M., Belaidi, M., Bufarwa, S., & Sadeek, S. A. (2025) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.114460 · Cited by 25

Effects of Green cardamom (Elettaria cardamomum Maton) and its combination with cyclophosphamide on Ehrlich solid tumors

Almeer, R., Alnasser, M., Aljarba, N. H., & Albasher, G. I. (2021) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03305-2 · Cited by 25

Protective effect of the association of curcumin with piperine on prostatic lesions: New perspectives on BPA-induced carcinogenesis

Facina, C. H., Campos, S. G. P., Ruiz, T. F. R., Góes, R. M., Vilamaior, P. S. L., & Taboga, S. R. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112700 · Cited by 25

Curcumin: A Potential Weapon in the Prevention and Treatment of Head and Neck Cancer

Veselá, K., Kejík, Z., Masařík, M., Babula, P., Dytrych, P., Pavel Martasek, E., & Jakubek, M. (2024) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.4c00518 · Cited by 26

Effect of selected spices on chemical and sensory markers in fortified rye‐buckwheat cakes

Starowicz, M., Zieliński, H., Ciesarová, Z., Kukurová, K., & Lamparski, G. (2016) · Food Science & Nutrition · doi:10.1002/fsn3.329 · Cited by 23

Target Identification and Polypharmacology of Nutraceuticals

Dormán, G., Flachner, B., Hajdú, I., & András, C. D. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802147-7.00021-8 · Cited by 22

Biocompatible polymeric nanoparticles as carriers for anticancer phytochemicals

Hnamte, M., & Pulikkal, A. K. (2023) · European Polymer Journal · doi:10.1016/j.eurpolymj.2023.112637 · Cited by 23

Spices and culinary herbs for the prevention and treatment of breast cancer: A comprehensive review with mechanistic insights

Ali, M. L., Noushin, F., Sadia, Q. A., Metu, A. F., Meem, J. N., Chowdhury, M. T., Rasel, M., Suma, K. J., Alim, M. A., Jalil, M. A., et al. (2024) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2024.07.003 · Cited by 21

Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways

Semlali, A., Ajala, I., Beji, S., Al-Zharani, M. M., & Rouabhia, M. (2023) · Pharmaceuticals · doi:10.3390/ph16050700 · Cited by 20

Synthesis of novel zerumbone derivatives via regioselective palladium catalyzed decarboxylative coupling reaction: a new class of α-glucosidase inhibitors

Ajish, K. R., Dhanya, B. P., Joseph, N., Rani, M. P., Raghu, K. G., Vineetha, V. P., & Radhakrishnan, K. V. (2013) · Tetrahedron Letters · doi:10.1016/j.tetlet.2013.11.110 · Cited by 20

Introducing a bionanocomposite (Ultrasound-assisted synthesis of Ag nanoparticles embedded Aloe vera gel) for the treatment of cervical carcinoma

Yan, J., Karmakar, B., Zaki, M. S. A., Osman, R., Abdalla, A. M., Shati, A. A., El-kott, A. F., Yousef, F. M., Aggad, S. S., & Batiha, G. E. (2022) · Journal of Experimental Nanoscience · doi:10.1080/17458080.2022.2134562 · Cited by 19

Myelopotentiating effect of curcumin in tumor-bearing host: Role of bone marrow resident macrophages

Vishvakarma, N. K., Kumar, A., Kumar, A., Kant, S., Bharti, A. C., & Singh, S. M. (2012) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2012.06.004 · Cited by 19

Evidence-based Integrative Medicine in Clinical Veterinary Oncology

Raditic, D., & Bartges, J. W. (2014) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2014.06.002 · Cited by 19

Impact of Natural Dietary Agents on Multiple Myeloma Prevention and Treatment: Molecular Insights and Potential for Clinical Translation

Raimondi, L., Luca, A. D., Giavaresi, G., Barone, A., Tagliaferri, P., Tassone, P., & Amodio, N. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180629153141 · Cited by 19

Molecular Targets of Nutraceuticals Derived from Dietary Spices: Potential Role in Suppression of Inflammation and Tumorigenesis

Aggarwal, B. B., Kuiken, M. E. V., Iyer, L. H., Harikumar, K. B., & Sung, B. (2009) · Experimental Biology and Medicine · doi:10.3181/0902-mr-78 · Cited by 204

Antitumor promoting potential of selected phytochemicals derived from spices

Rajput, S., & Mandal, M. (2011) · European Journal of Cancer Prevention · doi:10.1097/cej.0b013e32834a7f0c · Cited by 76

Potential of Spice-Derived Phytochemicals for Cancer Prevention

Aggarwal, B. B., Kunnumakkara, A. B., Harikumar, K. B., Tharakan, S. T., Sung, B., & Anand, P. (2008) · Planta Medica · doi:10.1055/s-2008-1074578 · Cited by 269

Spice up your food for cancer prevention: Cancer chemo-prevention by natural compounds from common dietary spices

Gao, J., Mamouni, K., Zhang, L., & Lokeshwar, B. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821710-8.00013-8 · Cited by 11

Anti-oncogenic perspectives of spices/herbs: A comprehensive review.

Butt, M. S., Naz, A., Sultan, M. T., & Qayyum, M. M. N. (2013) · EXCLI journal · Cited by 34