Cited by 128Stress Responses and CortisolAdrenal Hormones and DisordersAtherosclerosis and Cardiovascular Diseases

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Inflammation and cortisol response in coronary artery disease

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Nijm, Johnny, Jonasson, Lena·2009·Annals of Medicine

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Abstract

Atherosclerosis is characterized by chronic inflammation involving autoimmune components. The degree of inflammatory activity, as detectable both within the atherosclerotic plaque and in the circulation, is associated with plaque destabilization and atherothrombotic complications. Endogenous glucocorticoids are modulators of innate and acquired immune responses, and as such play a key role in the reciprocal interaction between neuroendocrine and immune systems. Abnormalities in hypothalamic-pituitary-adrenal axis (HPA) function have been described in several chronic inflammatory disorders, and evidence has emerged lately that HPA dysfunction may be implicated also in the pathogenesis of coronary artery disease. This review is an outline of knowledge gained so far by previous studies of glucocorticoids in coronary atherosclerosis and myocardial infarction. The results consistently point towards a dysregulated cortisol secretion that may involve a failure to contain inflammatory activity. A dysfunctional HPA axis and its possible implications for coronary artery disease progress, including the hypothetical link between stress and inflammation, are discussed.

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Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026
Inflammation, Atherosclerosis, and Coronary Artery Disease
Hansson, G. K. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043430 · Cited by 8,773
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0389 · Cited by 7,541
Adhesion receptors of the immune system
Springer, T. A. (1990) · Nature · doi:10.1038/346425a0 · Cited by 6,477
The ‘Trier Social Stress Test’—a tool for investigating psychobiological stress responses in a laboratory setting
Kirschbaum, C., Pirke, K.-M., & Hellhammer, D. H. (2008) · Neuropsychobiology · doi:10.1159/000119004 · Cited by 6,093
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003233421202 · Cited by 5,850
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
Ridker, P. M., Cushman, M., Stampfer, M. J., Tracy, R. P., & Hennekens, C. H. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704033361401 · Cited by 5,504
The Pathogenesis of Atherosclerosis — An Update
Ross, R. (1986) · New England Journal of Medicine · doi:10.1056/nejm198602203140806 · Cited by 4,885
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases: Structure, Function, and Biochemistry
Visse, R., & Nagase, H. (2003) · Circulation Research · doi:10.1161/01.res.0000070112.80711.3d · Cited by 4,575
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · cited 1×
“Nevertheless, CAD remains the leading cause of death in developed nations and is predicted to achieve that status worldwide within 10-15 years (8).”
Background
Functional diversity of helper T lymphocytes
Abbas, A. K., MURPHY, K. M. M., & Sher, A. (1996) · Nature · doi:10.1038/383787a0 · Cited by 4,432
Structure and function of matrix metalloproteinases and TIMPs
Nagase, H., Visse, R., & MURPHY, G. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.12.002 · Cited by 3,507
Matrix metalloproteinases and their inhibitors in connective tissue remodeling
Woessner, J. F. (1991) · The FASEB Journal · doi:10.1096/fasebj.5.8.1850705 · Cited by 3,281
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
Rhen, T., & Cidlowski, J. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050541 · Cited by 3,149
Brain corticosteroid receptor balance in health and disease
de Kloet, E. R., Vreugdenhil, E., Oitzl, M. S., & Joëls, M. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.3.0331 · Cited by 2,614
Cloning of a new cytokine that induces IFN-γ production by T cells
Okamura, H., Tsutsui, H., Komatsu, T., Yutsudo, M., Hakura, A., Tanimoto, T., Torigoe, K., Okura, T., Nukada, Y., Hattori, K., et al. (1995) · Nature · doi:10.1038/378088a0 · Cited by 2,602
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
Chrousos, G. P. (1995) · New England Journal of Medicine · doi:10.1056/nejm199505183322008 · Cited by 2,579
Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.
Galis, Z. S., Sukhova, G. K., Lark, M. W., & Libby, P. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117619 · Cited by 2,537
Association of psychosocial risk factors with risk of acute myocardial infarction in 11 119 cases and 13 648 controls from 52 countries (the INTERHEART study): case-control study
Rosengren, A., Hawken, S., Ôunpuu, S., Sliwa, K., Zubaid, M., Almahmeed, W. A., Blackett, K. N., Sitthi-amorn, C., Sato, H., & Yusuf, S. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17019-0 · Cited by 2,414
Inflammation. Basic principles and clinical correlates
(1989) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(89)90156-x · Cited by 2,388
The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina
Liuzzo, G., Biasucci, L. M., Gallimore, J. R., Grillo, R. L., Rebuzzi, A. G., Pepys, M. B., & Maseri, A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408183310701 · Cited by 2,354
The immune response in atherosclerosis: a double-edged sword
Hansson, G. K., & Libby, P. (2006) · Nature reviews. Immunology · doi:10.1038/nri1882 · Cited by 2,220
Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses
Danesh, J. (2000) · BMJ · doi:10.1136/bmj.321.7255.199 · Cited by 1,692
Effect of Statin Therapy on C-Reactive Protein Levels
Albert, M. A., Danielson, E., Rifai, N., Ridker, P. M., & for the PRINCE Investigators (2001) · JAMA · doi:10.1001/jama.286.1.64 · Cited by 1,644
Letter: Grading of angina pectoris.
CAMPEAU, L. A. (1976) · Circulation · doi:10.1161/circ.54.3.947585 · Cited by 1,607
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
Sakaguchi, S., Ono, M., Setoguchi, R., Yagi, H., Hori, S., Fehervari, Z. T., Shimizu, J., Takahashi, T., & Nomura, T. (2006) · Immunological Reviews · doi:10.1111/j.0105-2896.2006.00427.x · Cited by 1,589
Serological reactions in pneumonia with a non-protein somatic fraction of Pneumococcus
Tillett, W. S., & Francis, T. (1930) · Journal of Experimental Medicine · doi:10.1084/jem.52.4.561 · Cited by 1,482
Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity
Pruessner, J. C., Wolf, O. T., Hellhammer, D. H., Buske-Kirschbaum, A., von Auer, K., Jobst, S., Kaspers, F., & Kirschbaum, C. (1997) · Life Sciences · doi:10.1016/s0024-3205(97)01008-4 · Cited by 1,450
Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque.
Jonasson, L., Holm, J., Skalli, O., Bondjers, G., & Hansson, G. K. (1986) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.6.2.131 · Cited by 1,329
Self-citation
The pathogenesis of atherosclerosis
(1972) · American Heart Journal · doi:10.1016/0002-8703(72)90090-7 · Cited by 1,329
Novel Risk Factors for Systemic Atherosclerosis
Ridker, P. M., Stampfer, M. J., & Rifai, N. (2001) · JAMA · doi:10.1001/jama.285.19.2481 · Cited by 1,290
Diurnal Cortisol Rhythm as a Predictor of Breast Cancer Survival
Sephton, S. E. (2000) · Journal of the National Cancer Institute · doi:10.1093/jnci/92.12.994 · Cited by 1,082
Biological and clinical aspects of interleukin 6
Hirano, T., Akira, S., Taga, T., & Kishimoto, T. (1990) · Immunology Today · doi:10.1016/0167-5699(90)90173-7 · Cited by 1,062
Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
Frostegård, J., Ulfgren, A., Nyberg, P., Hedin, U., Swedenborg, J., Andersson, U., & Hansson, G. K. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(99)00011-8 · Cited by 1,002
Neuroendocrine Regulation of Immunity
Webster, J. I., Tonelli, L., & Sternberg, E. M. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.082401.104914 · Cited by 957
Human C-reactive protein: expression, structure, and function
Volanakis, J. E. (2001) · Molecular Immunology · doi:10.1016/s0161-5890(01)00042-6 · Cited by 950
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein.
Stemme, S., Faber, B., Holm, J., Wiklund, O., Witztum, J. L., & Hansson, G. K. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.9.3893 · Cited by 943
A mechanism converting psychosocial stress into mononuclear cell activation
Bierhaus, A., Wolf, J., Andrassy, M., Rohleder, N., Humpert, P. M., Petrov, D., Ferstl, R., von Eynatten, M., Wendt, T., Rudofsky, G., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0438019100 · Cited by 927
Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation
Flower, R. J., & Blackwell, G. J. (1979) · Nature · doi:10.1038/278456a0 · Cited by 927
Widespread Coronary Inflammation in Unstable Angina
Buffon, A., Biasucci, L. M., Liuzzo, G., d’Onofrio, G., Crea, F., & Maseri, A. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012295 · Cited by 917
Reciprocal Association of C-Reactive Protein With Adiponectin in Blood Stream and Adipose Tissue
Ouchi, N., Kihara, S., Funahashi, T., Nakamura, T., Nishida, M., Kumada, M., Okamoto, Y., Ohashi, K., Nagaretani, H., Kishida, K., et al. (2003) · Circulation · doi:10.1161/01.cir.0000055188.83694.b3 · Cited by 853
Interleukin-1, Interleukin-1 Receptors and Interleukin-1 Receptor Antagonist
Dinarello, C. A. (1998) · International Reviews of Immunology · doi:10.3109/08830189809043005 · Cited by 761
Plasma Concentrations and Genetic Variation of Matrix Metalloproteinase 9 and Prognosis of Patients With Cardiovascular Disease
Blankenberg, S., Rupprecht, H. J., Poirier, O., Bickel, C., Smieja, M., Hafner, G., Meyer, J., Cambien, F., & Tiret, L. (2003) · Circulation · doi:10.1161/01.cir.0000058700.41738.12 · Cited by 755
Elevated Levels of Interleukin-6 in Unstable Angina
Biasucci, L. M., Vitelli, A., Liuzzo, G., Altamura, S., Caligiuri, G., Monaco, C. G., Rebuzzi, A. G., Ciliberto, G., & Maseri, A. (1996) · Circulation · doi:10.1161/01.cir.94.5.874 · Cited by 738
Effect of Hydroxymethyl Glutaryl Coenzyme A Reductase Inhibitor Therapy on High Sensitive C-Reactive Protein Levels
Jialal, I., Stein, D. T., Balis, D. S., Grundy, S. M., ADAMS-HUET, B. A., & Devaraj, S. (2001) · Circulation · doi:10.1161/01.cir.103.15.1933 · Cited by 731
Triggering of Acute Myocardial Infarction Onset by Episodes of Anger
Mittleman, M. A., Maclure, M., Sherwood, J. B., Mulry, R. P., Tofler, G. H., Jacobs, S. C., Friedman, R. B., Benson, H., & Muller, J. E. (1995) · Circulation · doi:10.1161/01.cir.92.7.1720 · Cited by 707
The macrophage foam cell as a target for therapeutic intervention
Li, A. C., & Glass, C. K. (2002) · Nature Medicine · doi:10.1038/nm1102-1235 · Cited by 700
IL-6 and APPs: anti-inflammatory and immunosuppressive mediators.
Tilg, H., Dinarello, C., & Mier, J. (1997) · Immunology today (Amsterdam. Regular ed.) · doi:10.1016/s0167-5699(97)01103-1 · Cited by 687
Physical Exertion as a Trigger of Acute Myocardial Infarction
Willich, S. N., Lewis, M., Lowel, H., Arntz, H.-R., Schubert, F., & Schroder, R. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312023292302 · Cited by 682
Neutrophil Infiltration of Culprit Lesions in Acute Coronary Syndromes
Naruko, T., Ueda, M., Haze, K., van der Wal, A. C., van der Loos, C. M., Itoh, A., Komatsu, R., Ikura, Y., Ogami, M., Shimada, Y., et al. (2002) · Circulation · doi:10.1161/01.cir.0000042674.89762.20 · Cited by 660
Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer
Rose‐John, S., Scheller, J., Elson, G., & Jones, S. A. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.1105674 · Cited by 656
Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans
Bamberger, C. M., Bamberger, A. M., de Castro, M., & Chrousos, G. P. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117943 · Cited by 642
Expression of Interleukin-18 in Human Atherosclerotic Plaques and Relation to Plaque Instability
Mallat, Z., Corbaz, A., Scoazec, A., Besnard, S., Lesèche, G., Chvatchko, Y., & Tedgui, A. (2001) · Circulation · doi:10.1161/hc3901.096721 · Cited by 637
Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells
Ng, W., Duggan, P. J., Ponchel, F., Matarese, G., Lombardi, G., Edwards, A. D., Isaacs, J. D., & Lechler, R. I. (2001) · Blood · doi:10.1182/blood.v98.9.2736 · Cited by 606
Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes
Kai, H., Ikeda, H., Yasukawa, H., Kai, M., Seki, Y., Kuwahara, F., Ueno, T., Sugi, K., & Imaizumi, T. (1998) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00250-2 · Cited by 591
Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization.
HENNEY, A. M., Wakeley, P. R., Davies, M. J., Foster, K., Hembry, R. M., Murphy, G., & Humphries, S. E. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.18.8154 · Cited by 587
An HMG-CoA Reductase Inhibitor, Cerivastatin, Suppresses Growth of Macrophages Expressing Matrix Metalloproteinases and Tissue Factor In Vivo and In Vitro
Aikawa, M., Aikawa, E. R., Sugiyama, S., Voglic, S. J., Fukumoto, Y., Furukawa, Y., Shiomi, M., Schöen, F. J., & Libby, P. (2001) · Circulation · doi:10.1161/01.cir.103.2.276 · Cited by 587
Phagocytic activation of a luminol-dependent chemiluminescence in rabbit alveolar and peritoneal macrophages
Allen, R. C., & Loose, L. D. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(76)80299-9 · Cited by 572
A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.
Sternberg, E. M., Young, W. S., Bernardini, R., Calogero, A. E., Chrousos, G. P., Gold, P. W., & Wilder, R. L. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.12.4771 · Cited by 568
Interleukin-18 Is a Strong Predictor of Cardiovascular Death in Stable and Unstable Angina
Blankenberg, S., Tiret, L., Bickel, C., Peetz, D., Cambien, F., Meyer, J., & Rupprecht, H. J. (2002) · Circulation · doi:10.1161/01.cir.0000020546.30940.92 · Cited by 566
Relationship Between Interleukin 6 and Mortality in Patients With Unstable Coronary Artery Disease
Lindmark, E., Diderholm, E., Wallentin, L. C., & Siegbahn, A. (2001) · JAMA · doi:10.1001/jama.286.17.2107 · Cited by 563
Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.
Galis, Z. S., Sukhova, G. K., Kranzhöfer, R., Clark, S. C., & Libby, P. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.2.402 · Cited by 557
Adiponectin Specifically Increased Tissue Inhibitor of Metalloproteinase-1 Through Interleukin-10 Expression in Human Macrophages
Kumada, M., Kihara, S., Ouchi, N., Kobayashi, H., Okamoto, Y., Ohashi, K., Maeda, K., Nagaretani, H., Kishida, K., Maeda, N., et al. (2004) · Circulation · doi:10.1161/01.cir.0000127953.98131.ed · Cited by 555
Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes.
Liuzzo, G., Goronzy, J. J., Yang, H., Kopecky, S. L., Holmes, D. R., Frye, R. L., & Weyand, C. M. (2000) · Circulation · doi:10.1161/01.cir.101.25.2883 · Cited by 552
Several daily measurements are necessary to reliably assess the cortisol rise after awakening: State-and trait components
Hellhammer, J., Fries, E., Schweisthal, O. W., Schlotz, W., Stone, A. A., & Hagemann, D. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.10.005 · Cited by 540
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.
Diamond, M., García‐Aguilar, J., Bickford, J. K., Corbí, A. L., & Springer, T. A. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.120.4.1031 · Cited by 533
Functional diversity of T lymphocytes due to secretion of different cytokine patterns
Street, N. E., & Mosmann, T. R. (1991) · The FASEB Journal · doi:10.1096/fasebj.5.2.1825981 · Cited by 530
C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids
Chang, M.-K., Binder, C. J., Torzewski, M., & Witztum, J. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.192399699 · Cited by 521
The hypothalamic–pituitary–adrenal axis activity as a predictor of cardiovascular disease, type 2 diabetes and stroke
Rosmond, R., & Björntorp, P. A. (2000) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2000.00603.x · Cited by 513
HMG-CoA Reductase Inhibitors Reduce MMP-9 Secretion by Macrophages
Bellosta, S., Via, D. P., Canavesi, M., Pfister, P., Fumagalli, R., Paoletti, R., & Bernini, F. (1998) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.18.11.1671 · Cited by 512
EFFECTS OF CORTISONE ACETATE AND PITUITARY ACTH ON RHEUMATOID ARTHRITIS, RHEUMATIC FEVER AND CERTAIN OTHER CONDITIONS: A Study in Clinical Physiology
HENCH, P. S. (1950) · Archives of Internal Medicine · doi:10.1001/archinte.1950.00230100002001 · Cited by 501
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients
Heit, B., Tavener, S. A., Raharjo, E., & Kubes, P. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202114 · Cited by 487
Increasing Levels of Interleukin (IL)-1Ra and IL-6 During the First 2 Days of Hospitalization in Unstable Angina Are Associated With Increased Risk of In-Hospital Coronary Events
Biasucci, L. M., Liuzzo, G., Fantuzzi, G., Caligiuri, G., Rebuzzi, A. G., Ginnetti, F., Dinarello, C. A., & Maseri, A. (1999) · Circulation · doi:10.1161/01.cir.99.16.2079 · Cited by 484
Identification of 92-kD Gelatinase in Human Coronary Atherosclerotic Lesions
Brown, D., Hibbs, M. S., Kearney, M., Loushin, C., & Isner, J. M. (1995) · Circulation · doi:10.1161/01.cir.91.8.2125 · Cited by 483
Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance
Webster, J. C., Oakley, R. H., Jewell, C. M., & Cidlowski, J. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121455098 · Cited by 482
Nutrition, physical activity, and cardiovascular disease: An update
IGNARRO, L., Balestrieri, M. L., & Claudio Napoli, A. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.06.030 · Cited by 454
The Dominant Negative Activity of the Human Glucocorticoid Receptor β Isoform
Oakley, R. H., Jewell, C. M., Yudt, M. R., Bofetiado, D. M., & Cidlowski, J. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.39.27857 · Cited by 451
Increased Matrix Metalloproteinase-9 Activity in Unstable Carotid Plaques
Loftus, I. M., Naylor, A. R., Goodall, S., Crowther, M., Jones, L., Bell, P. R. F., & Thompson, M. M. (2000) · Stroke · doi:10.1161/01.str.31.1.40 · Cited by 419
Association of Glucocorticoid Insensitivity with Increased Expression of Glucocorticoid Receptor β
Leung, D. Y. M., Hamid, Q. A., Vottero, A., Szefler, S. J., Surs, W., Minshall, E., Chrousos, G. P., & Klemm, D. J. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.9.1567 · Cited by 407
Two conformations of the integrin A-domain (I-domain): a pathway for activation?
Lee, J., Bankston, L. A., & Liddington, M. A. A. A. R. C. (1995) · Structure · doi:10.1016/s0969-2126(01)00271-4 · Cited by 405
Cortisol in Saliva - Reference Ranges and Relation to Cortisol in Serum
Aardal, E., & Holm, A.-C. (1995) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.1995.33.12.927 · Cited by 402
Increased Neutrophil-Platelet Adhesion in Patients With Unstable Angina
Ott, I., Neumann, F., Gawaz, M., Schmitt, M., & Scho¨mig, A. (1996) · Circulation · doi:10.1161/01.cir.94.6.1239 · Cited by 402
Cellular adhesion molecules and atherogenesis
Price, D. T., & Loscalzo, J. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00153-9 · Cited by 388
Serum Level of the Antiinflammatory Cytokine Interleukin-10 Is an Important Prognostic Determinant in Patients With Acute Coronary Syndromes
Heeschen, C., Dimmeler, S., Hamm, C. W., Fichtlscherer, S., Boersma, E. H., Simoons, M. L., & Zeiher, A. M. (2003) · Circulation · doi:10.1161/01.cir.0000065232.57371.25 · Cited by 387
Integrin activation and structural rearrangement
Takagi, J., & Springer, T. A. (2002) · Immunological Reviews · doi:10.1034/j.1600-065x.2002.18613.x · Cited by 384
Simvastatin Reduces Expression of Cytokines Interleukin-6, Interleukin-8, and Monocyte Chemoattractant Protein-1 in Circulating Monocytes From Hypercholesterolemic Patients
Rezaie-Majd, A., Maca, T., Bucek, R. A., Valent, P., Müller, M. R., Husslein, P. W., Kashanipour, A., Minar, E., & Baghestanian, M. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000022694.16328.cc · Cited by 380
Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice
Elhage, R. (2003) · Cardiovascular Research · doi:10.1016/s0008-6363(03)00343-2 · Cited by 378
Inhibition of transcription factor NF-κB reduces matrix metalloproteinase-1, -3 and -9 production by vascular smooth muscle cells
Bond, M. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(01)00220-6 · Cited by 366
Analysis of possible triggers of acute myocardial infarction (the MILIS study)
Tofler, G. H., Stone, P. H., Maclure, M., Edelman, E., Davis, V. G., Robertson, T., Antman, E. M., & Muller, J. E. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)90729-k · Cited by 356
Role of Heat Shock Proteins in Atherosclerosis
Xu, Q. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000029720.59649.50 · Cited by 355
Aberrant inflammation and resistance to glucocorticoids in Annexin 1 −/− Mouse
Hannon, R., Croxtall, J. D., Getting, S. J., Roviezzo, F., Yona, S., Paul‐Clark, M. J., Gavins, F. N. E., Perretti, M., Morris, J. F., Buckingham, J. C., et al. (2002) · The FASEB Journal · doi:10.1096/fj.02-0239fje · Cited by 351
Cortisol, Testosterone, and Coronary Heart Disease: Prospective Evidence From the Caerphilly Study
Smith, G., Ben-Shlomo, Y., Beswick, A., Yarnell, J., Lightman, S., & Elwood, P. (2005) · Circulation · doi:10.1161/circulationaha.104.489088 · Cited by 348
Individual differences in the diurnal cycle of salivary free cortisol: a replication of flattened cycles for some individuals
Stone, A. A., Schwartz, J. E., Smyth, J. M., Kirschbaum, C., Cohen, S., Hellhammer, D. H., & Grossman, S. (2001) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(00)00057-3 · Cited by 347
Defective hypothalamic response to immune and inflammatory stimuli in patients with rheumatoid arthritis
Chikanza, I. C., Petrou, P., Kingsley, G., Chrousos, G., & Panayi, G. S. (1992) · Arthritis & Rheumatism · doi:10.1002/art.1780351107 · Cited by 337
Stress and the hypothalamo-pituitary-adrenal axis: acute, chronic and immunological activation
Harbuz, M. S., & Lightman, S. L. (1992) · Journal of Endocrinology · doi:10.1677/joe.0.1340327 · Cited by 334
Interleukin-10 Deficiency Increases Atherosclerosis, Thrombosis, and Low-density Lipoproteins in Apolipoprotein E Knockout Mice
Caligiuri, G., Rudling, M., Ollivier, V., Jacob, M., Michel, J., Hansson, G. K., & Nicoletti, A. (2003) · Molecular Medicine · doi:10.1007/bf03402102 · Cited by 333
Altered status of CD4+CD25+ regulatory T cells in patients with acute coronary syndromes
Mor, A., Luboshits, G., Planer, D., Keren, G., & George, J. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl222 · Cited by 332
Regulation of cytokine and cytokine receptor expression by glucocorticoids
Almawi, W. Y., Beyhum, H. N., Rahme, A. A., & Rieder, M. J. (1996) · Journal of Leukocyte Biology · doi:10.1002/jlb.60.5.563 · Cited by 329
Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein.
Gabay, C., Smith, M. F., Eidlen, D. M., & Arend, W. P. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119488 · Cited by 325
Production of interleukin-1-receptor antagonist during experimental endotoxaemia
Granowitz, E. V., Poutsiaka, D. D., Cannon, J. G., Wolff, S. M., Dinarello, C. A., Santos, A. A., & Wilmore, D. W. (1991) · The Lancet · doi:10.1016/0140-6736(91)92725-h · Cited by 311
The hypothalamic–pituitary–adrenal (HPA) axis in habitual smokers
Rohleder, N., & Kirschbaum, C. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2005.10.012 · Cited by 307
Oxidized Low-Density Lipoprotein Regulates Matrix Metalloproteinase-9 and Its Tissue Inhibitor in Human Monocyte-Derived Macrophages
Xu, X., Meisel, S. R., Ong, J. M., Kaul, S., Cercek, B., Rajavashisth, T. B., Sharifi, B. G., & Shah, P. K. (1999) · Circulation · doi:10.1161/01.cir.99.8.993 · Cited by 299
Leukotriene B4 in inflammation.
Ford‐Hutchinson, A. W. (1990) · PubMed · Cited by 297
Annexin 1: more than an anti-phospholipase protein
Parente, L., & Solito, E. (2004) · Inflammation Research · doi:10.1007/s00011-003-1235-z · Cited by 288
The relationship between smoking status and cortisol secretion.
Badrick, E., Kirschbaum, C., & Kumari, M. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2155 · Cited by 284
Plasma levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 are increased in the coronary circulation in patients with acute coronary syndrome
Inokubo, Y., Hanada, H., Ishizaka, H., Fukushi, T., Kamada, T., & Okumura, K. (2001) · American Heart Journal · doi:10.1067/mhj.2001.112238 · Cited by 283
Membrane Type 1 Matrix Metalloproteinase Expression in Human Atherosclerotic Plaques
Rajavashisth, T. B., Xu, X., Jovinge, S. V., Meisel, S. R., Xu, X.-O. H., Chai, N., Fishbein, M. C., Kaul, S., Cercek, B., Sharifi, B. G., et al. (1999) · Circulation · doi:10.1161/01.cir.99.24.3103 · Cited by 280
Glucocorticoids: exemplars of multi-tasking
Buckingham, J. C. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706456 · Cited by 276
C‐Reactive Protein (CRP)‐Lowering Agents
Prasad, K. (2006) · Cardiovascular Drug Reviews · doi:10.1111/j.1527-3466.2006.00033.x · Cited by 274
Enhanced Expression of Vascular Matrix Metalloproteinases Induced In Vitro by Cytokines and in Regions of Human Atherosclerotic Lesionsa
Galis, Z. S., Muszynski, M., Sukhova, G. K., SIMON‐MORRISSEY, E., & Libby, P. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb17348.x · Cited by 273
Neutrophil function in ischemic heart disease.
Mehta, J. L., DINERMAN, J. L., Mehta, P., Saldeen, T. G. P., Dl, L., Donnelly, W. H., & Wallin, R. (1989) · Circulation · doi:10.1161/01.cir.79.3.549 · Cited by 272
Untitled work
(2001) · PubMed · Cited by 266
Dynamic mechanisms in human coronary stenosis.
Brown, B. G., Bolson, E. L., & Dodge, H. T. (1984) · Circulation · doi:10.1161/01.cir.70.6.917 · Cited by 261
Expression of glucocorticoid receptor β in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis
Honda, M., Orii, F., Ayabe, T., Imai, S., Ashida, T., Obara, T., & Kohgo, Y. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)70172-7 · Cited by 252
Atherosclerotic lesions in humans. In situ immunophenotypic analysis suggesting an immune mediated response.
van der Wal, A. C., Das, P. K., Berg, D., van der Loos, C. M., & Becker, A. E. (1989) · PubMed · Cited by 251
Immunoradiometric Assay of Circulating C-Reactive Protein: Age-related Values in the Adult General Population
Hutchinson, W. L., Köenig, W., Fröhlich, M., Sund, M., Lowe, G. D. O., & Pepys, M. B. (2000) · Clinical Chemistry · doi:10.1093/clinchem/46.7.934 · Cited by 250
Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice.
Zhou, X., Stemme, S., & Hansson, G. K. (1996) · Europe PMC (PubMed Central) · Cited by 249
Serum Levels of the Antiinflammatory Cytokine Interleukin-10 Are Decreased in Patients With Unstable Angina
Smith, D. A., Irving, S. D., Sheldon, J., Cole, D., & Kaski, J. C. (2001) · Circulation · doi:10.1161/hc3201.094973 · Cited by 248
Statins Reduce Interleukin-6–Induced C-Reactive Protein in Human Hepatocytes: New Evidence for Direct Antiinflammatory Effects of Statins
Arnaud, C., Burger, F., Steffens, S., Veillard, N. R., Nguyen, T. H., Trono, D., & Mach, F. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000163840.63685.0c · Cited by 247
Altered Responsiveness of the Hypothalamus-Pituitary-Adrenal Axis and the Sympathetic Adrenomedullary System to Stress in Patients with Atopic Dermatitis
Buske-Kirschbaum, A., Geiben, A. C., Höllig, H., Morschhäuser, E., & Hellhammer, D. H. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2001-010872 · Cited by 242
The Physiology of Human Glucocorticoid Receptor β (hGRβ) and Glucocorticoid Resistance
LEWIS‐TUFFIN, L. J., & CIDLOWSKI, J. A. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1351.001 · Cited by 242
Circadian Relationships between Interleukin (IL)-6 and Hypothalamic-Pituitary-Adrenal Axis Hormones: Failure of IL-6 to Cause Sustained Hypercortisolism in Patients with Early Untreated Rheumatoid Arthritis
Crofford, L. J. (1997) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.4.1279 · Cited by 242
Diurnal cortisol decline is related to coronary calcification: CARDIA study
Matthews, K., Schwartz, J., Cohen, S., & Seeman, T. (2006) · Psychosomatic Medicine · doi:10.1097/01.psy.0000244071.42939.0e · Cited by 240
Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement
Hayhoe, R. P. G., Kamal, A. M., Solito, E., Flower, R. J., Cooper, D., & Perretti, M. (2005) · Blood · doi:10.1182/blood-2005-08-3099 · Cited by 239
Expression of Ep-CAM in normal, regenerating, metaplastic, and neoplastic liver
de Boer, C. J., van Krieken, J. H., Rhijn, C. M. J., & Litvinov, S. V. (1999) · The Journal of Pathology · doi:10.1002/(sici)1096-9896(199906)188:2 · Cited by 237
Syndromes of Glucocorticoid Resistance
Chrousos, G. P., Detera-Wadleigh, S. D., & Karl, M. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-119-11-199312010-00009 · Cited by 235
Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay.
Mosmann, T. R., Schumacher, J. H., Fiorentino, D. F., Leverah, J. A., Moore, K. W., & Bond, M. W. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.145.9.2938 · Cited by 231
C-reactive protein in atherosclerosis: A causal factor?
Paffen, E., & de Maat, M. P. M. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.03.004 · Cited by 225
Isoluminol-enhanced chemiluminescence: A sensitive method to study the release of superoxide anion from human neutrophils
Lundqvist, H., & Dahlgren, C. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02189-2 · Cited by 221 · cited 1×
“The extracellular ROS production can be measured exclusively if luminol is exchanged for the very similar, but membrane impermeable molecule, isoluminol (203).”
Background
The association of elevated plasma cortisol and early atherosclerosis as demonstrated by coronary angiography
Troxler, R. G., Sprague, E. A., Albanese, R. A., FUCHS, R., & THOMPSON, A. (1977) · Atherosclerosis · doi:10.1016/0021-9150(77)90098-3 · Cited by 219
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1
Perretti, M., & Flower, R. J. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.150.3.992 · Cited by 218
Intra- and extracellular events in luminol-dependent chemiluminescence of polymorphonuclear leukocytes
Briheim, G., Stendahl, O. I., & Dahlgren, C. (1984) · Infection and Immunity · doi:10.1128/iai.45.1.1-5.1984 · Cited by 214
Effects of anger on left ventricular ejection fraction in coronary artery disease
Ironson, G. H., Taylor, C. B., Boltwood, M. D., Bartzokis, T. C., Dennis, C. A., Chesney, M. A., Spitzer, S. B., & Segall, G. M. (1992) · The American Journal of Cardiology · doi:10.1016/0002-9149(92)90605-x · Cited by 214
Coronary thrombosis: Pathogenesis and clinical manifestations
Falk, E. (1991) · The American Journal of Cardiology · doi:10.1016/0002-9149(91)90382-u · Cited by 214
Neutrophil serine proteases: potential key regulators of cell signalling during inflammation
Wiedow, O., & Meyer‐Hoffert, U. (2005) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2005.01476.x · Cited by 212
Immunoendocrine Communication via the Hypothalamo-Pituitary-Adrenal Axis in Autoimmune Diseases*
Wick, G., HU, Y., Schwarz, S., & Kroemer, G. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-5-539 · Cited by 208
Growth Factors and Cytokines Upregulate Gelatinase Expression in Bone Marrow CD34+ Cells and Their Transmigration Through Reconstituted Basement Membrane
Janowska‐Wieczorek, A., Marquez‐Curtis, L. A., Nabholtz, J., Cabuhat, M., Montaño, J., Chang, H., Rozmus, J., Russell, J. A., Edwards, D. R., & Turner, A. R. (1999) · Blood · doi:10.1182/blood.v93.10.3379.410k09_3379_3390 · Cited by 207
Relationship Between C-Reactive Protein and Subclinical Atherosclerosis
Khera, A., de Lemos, J. A., Peshock, R. M., Lo, H. S., Stanek, H. G., Murphy, S. A., Wians, F. H., Grundy, S. M., & McGuire, D. K. (2005) · Circulation · doi:10.1161/circulationaha.105.575241 · Cited by 202
Functional Characterization of Human IL-10
Spits, H., & Malefyt, R. D. W. (2009) · International Archives of Allergy and Immunology · doi:10.1159/000236329 · Cited by 201
Clopidogrel but not aspirin reduces P‐selectin expression and formation of platelet‐leukocyte aggregates in patients with atherosclerotic vascular disease*
Klinkhardt, U., Bauersachs, R. M., Adams, J., Graff, J., Lindhoff‐Last, E., & Harder, S. (2003) · Clinical Pharmacology & Therapeutics · doi:10.1067/mcp.2003.13 · Cited by 193
Stress, glucocorticoids and ageing of the immune system
Bauer, M. E. (2005) · Stress · doi:10.1080/10253890500100240 · Cited by 191
Acute T-Cell Activation Is Detectable in Unstable Angina
Serneri, G. G. N., Prisco, D., Martini, F., Gori, A. M., Brunelli, T., Poggesi, L., Rostagno, C., Gensini, G. F., & Abbate, R. (1997) · Circulation · doi:10.1161/01.cir.95.7.1806 · Cited by 185
Leukocyte Engagement of Platelet Glycoprotein Ibα via the Integrin Mac-1 Is Critical for the Biological Response to Vascular Injury
Wang, Y., Sakuma, M., Chen, Z., Ustinov, V., Shi, C., Croce, K., Zago, A. C., López, J. A., André, P., Plow, E. F., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.571315 · Cited by 183
Glucocorticoid hormone resistance during primate evolution: receptor-mediated mechanisms
Chrousos, G. P., Renquist, D., Brandon, D., Eil, C., Pugeat, M., Vigersky, R., Cutler, G. B., Loriaux, D. L., & Lipsett, M. B. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.6.2036 · Cited by 179
Enhanced T-Helper-1 Lymphocyte Activation Patterns in Acute Coronary Syndromes
Methe, H., Brunner, S., Wiegand, D., Näbauer, M., Koglin, J., & Edelman, E. R. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.03.040 · Cited by 178
Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes
Avolio, C., Ruggieri, M., Giuliani, F., Liuzzi, G. M., Leante, R., Riccio, P., Livrea, P., & Trojano, M. (2003) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(03)00006-7 · Cited by 176
Interferon-γ and Lipopolysaccharide Potentiate Monocyte Tissue Factor Induction by C-Reactive Protein
Nakagomi, A., Freedman, B., & Geczy, C. L. (2000) · Circulation · doi:10.1161/01.cir.101.15.1785 · Cited by 175
Circadian variation in disease activity in rheumatoid arthritis.
Harkness, J. A., Richter, M. B., Panayi, G. S., de Pette, K. V., Unger, A., Pownall, R., & Geddawi, M. (1982) · BMJ · doi:10.1136/bmj.284.6315.551 · Cited by 171
Leukocyte-Derived Interleukin 10 Is Required for Protection Against Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice
Potteaux, S., Esposito, B., van Oostrom, O., Brun, V., Ardouin, P., Groux, H., Tedgui, A., & Mallat, Z. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000134378.86443.cd · Cited by 170
The ups and downs of glucocorticoid physiology Permissive and suppressive effects revisited
Munck, A. U., & Náray‐Fejes‐Tóth, A. (1992) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(92)90091-j · Cited by 169
The monocyte-derived neutrophil activating peptide (NAP/interleukin 8) stimulates human neutrophil arachidonate-5-lipoxygenase, but not the release of cellular arachidonate.
Schröder, J. ‐. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.170.3.847 · Cited by 169
Cortisol awakening response is elevated in acute coronary syndrome patients with type-D personality
Whitehead, D. L., Perkins-Porras, L., Strike, P. C., Magid, K. S., & Steptoe, A. (2007) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2006.11.005 · Cited by 163
Increased Expression of Interleukin-1 in Coronary Artery Disease With Downregulatory Effects of HMG-CoA Reductase Inhibitors
Wæhre, T., Yndestad, A., Smith, C., Haug, T., Tunheim, S. H., Gullestad, L. L., Frøland, S. S., Semb, A. G., Aukrust, P., & Damås, J. K. (2004) · Circulation · doi:10.1161/01.cir.0000125700.33637.b1 · Cited by 163
Anti-Inflammatory Effects of Pioglitazone and/or Simvastatin in High Cardiovascular Risk Patients With Elevated High Sensitivity C-Reactive Protein
Hanefeld, M., Marx, N., Pfützner, A., Baurecht, W., Lübben, G., Karagiannis, E., Stier, U., & Forst, T. M. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.054 · Cited by 161
Systemic inflammation in unstable angina is the result of myocardial necrosis
Cusack, M. R., Marber, M. S., Lambiase, P. D., Bucknall, C. A., & Redwood, S. R. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)01899-5 · Cited by 159
Circulating Matrix Metalloproteinases and Their Inhibitors in Premature Coronary Atherosclerosis
Noji, Y., Kajinami, K., Kawashiri, M., Todo, Y., Horita, T., Nohara, A., Higashikata, T., Inazu, A., Koizumi, J., Takegoshi, T., et al. (2001) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2001.060 · Cited by 151
Local Release of C-Reactive Protein From Vulnerable Plaque or Coronary Arterial Wall Injured by Stenting
Inoue, T., Kato, T., Uchida, T., Sakuma, M., Nakajima, A., Shibazaki, M., Imoto, Y., Saito, M., Hashimoto, S., Hikichi, Y., et al. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.04.029 · Cited by 150
Increased plasma concentrations of interleukin-18 in acute coronary syndromes
Mallat, Z., Henry, P., Fressonnet, R., Alouani, S., Scoazec, A., Beaufils, P., Chvatchko, Y., & Tedgui, A. (2002) · Heart · doi:10.1136/heart.88.5.467 · Cited by 150
Genetic alterations of IL-1 receptor antagonist in mice affect plasma cholesterol level and foam cell lesion size
Devlin, C. M., Kuriakose, G., Hirsch, E., & Tabas, I. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092324399 · Cited by 147
Increased Cortisol Bioavailability, Abdominal Obesity, and the Metabolic Syndrome in Obese Women
Duclos, M., Pereira, P. M., Barat, P., Gatta‐Cherifi, B., & Roger, P. (2005) · Obesity Research · doi:10.1038/oby.2005.137 · Cited by 146
Molecular Biology of the H-2 Histocompatibility Complex
Flavell, R. A., Allen, H., Burkly, L. C., Sherman, D. H., Waneck, G. L., & Widera, G. (1986) · Science · doi:10.1126/science.3726537 · Cited by 146
Cerebrospinal fluid and serum levels and intrathecal production of active matrix metalloproteinase-9 (MMP-9) as markers of disease activity in patients with multiple sclerosis
Fainardi, E., Castellazzi, M., Bellini, T., Manfrinato, M. C., Baldi, E., Casetta, I., Paolino, E., Granieri, E., & Dallocchio, F. (2006) · Multiple Sclerosis Journal · doi:10.1191/135248506ms1274oa · Cited by 145
Carotid atherosclerotic plaques in patients with transient ischemic attacks and stroke have unstable characteristics compared with plaques in asymptomatic and amaurosis fugax patients
Verhoeven, B. A. N., Hellings, W. E., Moll, F. L., de Vries, J. P., de Kleijn, D. P. V., de Bruin, P. C., Busser, E., SCHONEVELD, A., & Pasterkamp, G. (2005) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2005.08.009 · Cited by 144
Annexin 1 and the biology of the neutrophil
Perretti, M., & Flower, R. J. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.1103552 · Cited by 142
Comparison of Levels of Serum Matrix Metalloproteinase-9 in Patients With Acute Myocardial Infarction Versus Unstable Angina Pectoris Versus Stable Angina Pectoris
Fukuda, D., Shimada, K., Tanaka, A., Kusuyama, T., Yamashita, H., Ehara, S., Nakamura, Y., Kawarabayashi, T., Iida, H., Yoshiyama, M., et al. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.08.020 · Cited by 139
Proinflammatory Effects of Bacterial Recombinant Human C-Reactive Protein Are Caused by Contamination With Bacterial Products, Not by C-Reactive Protein Itself
Pepys, M. B., Hawkins, P. N., Kahan, M., Tennent, G. A., Gallimore, J. R., Graham, D., Sabin, C. A., Zychlinsky, A., & de Diego, J. (2005) · Circulation Research · doi:10.1161/01.res.0000193595.03608.08 · Cited by 135
Tissue inhibitor of metalloproteinase-1 (TIMP-1) is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction
Çavuşoğlu, E., Ruwende, C., Chopra, V., Yanamadala, S., Eng, C., Clark, L. T., Pinsky, D. J., & Marmur, J. D. (2006) · American Heart Journal · doi:10.1016/j.ahj.2006.02.029 · Cited by 135
Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma
Gerlach, R. F., Demacq, C., Jung, K., & Tanus-Santos, J. E. (2006) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2006.10.007 · Cited by 133
Fluvastatin Inhibits Matrix Metalloproteinase-1 Expression in Human Vascular Endothelial Cells
Ikeda, U., Shimpo, M., Ohki, R., Inaba, H., Takahashi, M., Yamamoto, K., & Shimada, K. (2000) · Hypertension · doi:10.1161/01.hyp.36.3.325 · Cited by 133
High-sensitivity C-reactive protein in high-grade carotid stenosis: risk marker for unstable carotid plaque
Álvarez, B., Ruiz-Marcellán, C., Chacón, P. M., Álvarez‐Sabín, J., & Matas, M. (2003) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(03)00709-2 · Cited by 130
Evidence for Antigen-Driven T-Cell Response in Unstable Angina
Caligiuri, G., Paulsson, G. B., Nicoletti, A., Maseri, A., & Hansson, G. K. (2000) · Circulation · doi:10.1161/01.cir.102.10.1114 · Cited by 127
Differences in the ingestion mechanisms of IgG and C3b particles in phagocytosis by neutrophils.
HED, J., & Stendahl, O. I. (1982) · PubMed · Cited by 127
Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion.
Stearns, M. E., Rhim, J. S., & Wang, M. (1999) · PubMed · Cited by 126
A family of ligands for the TNF receptor superfamily
Cosman, D. J. (1994) · Stem Cells · doi:10.1002/stem.5530120501 · Cited by 126
Human glucocorticoid receptor cDNA contains sequences sufficient for receptor down-regulation.
Burnstein, K. L., Jewell, C. M., & Cidlowski, J. A. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39112-4 · Cited by 124
Depression and 24-hour urinary cortisol in medical outpatients with coronary heart disease: The Heart and Soul Study
Otte, C., Marmar, C. R., Pipkin, S. S., Moos, R. H., Browner, W. S., & Whooley, M. A. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.06.003 · Cited by 124
Critical Protective Role for Annexin 1 Gene Expression in the Endotoxemic Murine Microcirculation
Damazo, A. S., Yona, S., D’Acquisto, F., Flower, R. J., Oliani, S. M., & Perretti, M. (2005) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62471-6 · Cited by 124
Regulation of human C-reactive protein gene expression by two synergistic IL-6 responsive elements.
Li, S.-P., & Goldman, N. D. (1996) · Biochemistry · doi:10.1021/bi953033d · Cited by 119
AUUUA motifs in the 3′UTR of human glucocorticoid receptor α and β mRNA destabilize mRNA and decrease receptor protein expression
Schaaf, M. J. M., & Cidlowski, J. A. (2002) · Steroids · doi:10.1016/s0039-128x(02)00015-6 · Cited by 117
The Interleukin 2 Receptor
Smith, K. A. (1988) · Advances in immunology · doi:10.1016/s0065-2776(08)60844-5 · Cited by 116
Th1 and Th2 T-helper cells exert opposite regulatory effects on procoagulant activity and tissue factor production by human monocytes
Prete, G. D., Carli, M., Lammel, R. M., D’Elios, M. M., Daniel, K., Giusti, B., Abbate, R., & Romagnani, S. (1995) · Blood · doi:10.1182/blood.v86.1.250.bloodjournal861250 · Cited by 116
Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase‐3 activation
Solito, E., de Coupade, C., Canaider, S., Goulding, N. J., & Perretti, M. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704054 · Cited by 115
Effects of interleukin-10 on monocyte/endothelial cell adhesion and MMP-9/TIMP-1 secretion
Mtairag, E. M. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(00)00287-x · Cited by 114
Involvement of C-reactive protein obtained by directional coronary atherectomy in plaque instability and developing restenosis in patients with stable or unstable angina pectoris
Ishikawa, T., Hatakeyama, K., Imamura, T., Date, H., Shibata, Y., Hikichi, Y., Asada, Y., & Eto, T. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)03156-9 · Cited by 113
Glucocorticoid Receptor Gene and Risk of Cardiovascular Disease
van den Akker, E. L. T. (2008) · Archives of Internal Medicine · doi:10.1001/archinternmed.2007.41 · Cited by 112
Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemia
Kovacs, A., Tornvall, P., Nilsson, R., Tegner, J. N., Hamsten, A., & Björkegren, J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706027104 · Cited by 111
Evidence for altered hypothalamus–pituitary–adrenal axis functioning in systemic hypertension: Blunted cortisol response to awakening and lower negative feedback sensitivity
Wirtz, P. H., von Känel, R., Emini, L., Rüdisüli, K., Groessbauer, S., Maercker, A. R. A., & Ehlert, U. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.02.006 · Cited by 110
Psychophysiologic Strategies in Laboratory Research
Schneiderman, N., & McCabe, P. M. (1989) · Springer eBooks · doi:10.1007/978-1-4899-0906-0_22 · Cited by 110
Untitled work
(1999) · PubMed · Cited by 109
A 5‐year follow‐up study of disease incidence in men with an abnormal hormone pattern
Rosmond, R., Wallerius, S., Wanger, P., Martin, L., Holm, G., & Björntorp, P. A. (2003) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2003.01205.x · Cited by 108
Comparison of the prognostic value of C-Reactive protein and troponin I in patients with unstable angina pectoris
Benamer, H., Steg, P. G., Bénessiano, J., Vicaut, É., Gaultier, C. J., Boccara, A., Aubry, P., Nicaise‐Roland, P., Brochet, É., Juliard, J., et al. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00490-1 · Cited by 108
C-Reactive Protein and Coronary Artery Calcification
Reilly, M. P., Wolfe, M. L., Localio, A. R., & Rader, D. J. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000092327.60858.4a · Cited by 107
Age and sex steroid-related changes in glucocorticoid sensitivity of pro-inflammatory cytokine production after psychosocial stress
Rohleder, N., Kudielka, B. M., Hellhammer, D. H., Wolf, J. M., & Kirschbaum, C. (2002) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(02)00062-0 · Cited by 107
Glucocorticoid receptors in rheumatoid arthritis
Schlaghecke, R., Kornely, E., Wollenhaupt, J., & Specker, C. (1992) · Arthritis & Rheumatism · doi:10.1002/art.1780350704 · Cited by 107
Transforming Growth Factor-β1 Induces Tissue Inhibitor of Metalloproteinase-1 Expression via Activation of Extracellular Signal-Regulated Kinase and Sp1 in Human Fibrosarcoma Cells
Kwak, H., Park, M., Cho, H., Park, C.-M., Moon, S., Lee, H.-C., Park, I., Kim, M.-S., Rhee, C. H., & Hong, S. (2006) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-05-0140 · Cited by 107
IFNβ lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS
Waubant, E. L., Goodkin, D., Bostrom, A., Bacchetti, P., Hietpas, J., Lindberg, R. L. P., & Leppert, D. (2003) · Neurology · doi:10.1212/wnl.60.1.52 · Cited by 105
Plasma Matrix Metalloproteinase-9, Tissue Inhibitor of Metalloproteinase-2, and CD40 Ligand Levels in Patients With Stable Coronary Artery Disease
Tayebjee, M. H., Lip, G. Y. H., Tan, K. T., Patel, J. V., Hughes, E. A., & MacFadyen, R. J. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.03.072 · Cited by 103
Comparative Effects of Diet and Statin on NO Bioactivity and Matrix Metalloproteinases in Hypercholesterolemic Patients With Coronary Artery Disease
Koh, K. K., Son, J. W., Ahn, J. Y., Jin, D., Kim, H. S., Choi, Y. M., Kim, D. S., Jeong, E.-M., Park, G. S., Choi, I. S., et al. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000030997.02059.bb · Cited by 103
Cytokines: regulation of the hypothalamo-pituitary-adrenocortical axis
JOHN, C., & BUCKINGHAM, J. (2003) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(02)00009-7 · Cited by 102
Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA down-regulation through multiple mechanisms
Burnstein, K. L., Jewell, C. M., Sar, M., & Cidlowski, J. A. (1994) · Molecular Endocrinology · doi:10.1210/mend.8.12.7708063 · Cited by 102

Research works printed but not linked: 11

Li W, 2008, Atherosclerosis
Sapolsky RM, 2000, Endocr Rev., 21, 55
Buckingham JC, 2006, 147 Suppl, 1, S258
De Kloet ER, 1998, Endocr Rev., 19, 269
Aardal E, 1995, Eur J Clin Chem Clin Biochem., 33, 927
Kirschbaum C, 1999, Noise Health., 4, 57
Wick G, 1993, Endocr Rev., 14, 539
Travia D, 1995, J Clin Endocrinol Metab., 80, 836
Gutiérrez MA, 1999, J Rheumatol., 26, 277
Steensberg A, 2003, Exerc Immunol Rev., 9, 40
Derijk RH, 2001, J Rheumatol., 28, 2383

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“coronary heart disease [67–69].”
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Bevans, M., & Sternberg, E. M. (2012) · JAMA · doi:10.1001/jama.2012.29 · Cited by 620
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Hatzenbuehler, M. L., & McLaughlin, K. A. (2013) · Annals of Behavioral Medicine · doi:10.1007/s12160-013-9556-9 · Cited by 232
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Slopen, N., McLaughlin, K. A., & Shonkoff, J. P. (2014) · Pediatrics · doi:10.1542/peds.2013-1632 · Cited by 211
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Authors: Nijm, J., & Jonasson, L.
Affiliations: Ryhov Hospital Jönköping (SE)
Linköping University (SE)
ORCID: Jonasson, Lena
Venue: Annals of Medicine
Publisher: Informa UK Limited
Published: 2009-01
Volume: 41
Issue: 3
Pages: 224-233
ISSN: 0785-3890 (ISSN-L)
1365-2060
DOI: 10.1080/07853890802508934
OpenAlex: W2027066260
Cited by: 128
References: 282
Citations by year: 2026: 5 · 2025: 9 · 2024: 9 · 2023: 8 · 2022: 11 · 2021: 7 · 2020: 5 · 2019: 1 · 2018: 8 · 2017: 8 · 2016: 12 · 2015: 10 · 2014: 4 · 2013: 6 · 2012: 8
FWCI: 2.56
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Annals of Medicine (publishedVersion)
PubMed (publishedVersion)
DiVA (Linkoping University) (submittedVersion, other-oa)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
Keywords: coronary artery disease, atherosclerosis, inflammation, cortisol, hypothalamic-pituitary-adrenal axis, glucocorticoids, myocardial infarction, stress, neuroendocrine-immune interaction, plaque destabilization, atherothrombosis
MeSH terms: Coronary Artery Disease, Glucocorticoids, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Inflammation, Myocardial Infarction, Pituitary-Adrenal System, Stress, Physiological, Neuroimmunomodulation, Biomarkers, Autoimmunity

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Inflammation and cortisol response in coronary artery disease

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