The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.
Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial
Abstract
Significant evidence from epidemiological investigations showed that dietary polyphenols might manage and prevent type 2 diabetes (T2D). This review summarizes human studies and clinical trials of polyphenols as anti-diabetic agents. Polyphenols from coffee, guava tea, whortleberry, olive oil, propolis, chocolate, red wine, grape seed, and cocoa have been reported to show anti-diabetic effects in T2D patients through increasing glucose metabolism, improving vascular function as well as reducing insulin resistance and HbA1c level. However, individual flavonoid or isoflavonoid compounds appear to have no therapeutic effect on diabetes, based on the limited clinical data. Preliminary clinical trials provided evidence that resveratrol had anti-diabetic activity in humans by improving glycemic control in subjects with insulin resistance. Besides, anthocyanins exhibited anti-diabetic properties by reducing blood glucose and HbA1c levels or the improvement of insulin secretion and resistance. The structure-activity relationship of polyphenols as anti-diabetic agents in humans has been rarely reported.
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Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review
van Dam, R. M., & Hu, F. B. (2005) · JAMA · doi:10.1001/jama.294.1.97 · Cited by 662
Dietary Flavonoid Aglycones and Their Glycosides: Which Show Better Biological Significance?
Xiao, J. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1032400 · Cited by 591
Self-citationDietary flavonoid intakes and risk of type 2 diabetes in US men and women
Wedick, N. M., Pan, A., Cassidy, A., Rimm, E. B., Sampson, L., Rosner, B., Willett, W., Hu, F. B., Sun, Q., & van Dam, R. M. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.028894 · Cited by 515
Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus
Bhatt, J. K., Thomas, S., & Nanjan, M. J. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.06.003 · Cited by 475
Advance on the Flavonoid C-glycosides and Health Benefits
Xiao, J., Capanoglu, E., Jassbi, A. R., & Miron, A. (2016) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1067595 · Cited by 461
Self-citationWhat Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
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Self-citationMatsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., & Matsumoto, K. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf001251u · Cited by 396
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Cited by
Zhao, C., Yang, C., Wai, S. T. C., Zhang, Y., P. Portillo, M., Paoli, P., Wu, Y., San Cheang, W., Liu, B., Carpéné, C., et al. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1501658 · Cited by 199
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Metadata
- Authors
- Cao, H., Ou, J., Chen, L., Zhang, Y., Szkudelski, T., Delmas, D., Daglia, M., & Xiao, J.
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2018-11-19
- Volume
- 59
- Issue
- 20
- Pages
- 3371-3379
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W2843861620
- Cited by
- 293
- References
- 89
- FWCI
- 21.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cao, H., Ou, J., Chen, L., Zhang, Y., Szkudelski, T., Delmas, D., Daglia, M., & Xiao, J. (2019). Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial. Critical Reviews in Food Science and Nutrition. https://doi.org/10.1080/10408398.2018.1492900
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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