The DOI matches its Crossref record; 212 of the 212 references it cites were found in a registry or an index.
Regulation of Bacterial RecA Protein Function
Abstract
The RecA protein is a recombinase functioning in recombinational DNA repair in bacteria. RecA is regulated at many levels. The expression of the recA gene is regulated within the SOS response. The activity of the RecA protein itself is autoregulated by its own C-terminus. RecA is also regulated by the action of other proteins. To date, these include the RecF, RecO, RecR, DinI, RecX, RdgC, PsiB, and UvrD proteins. The SSB protein also indirectly affects RecA function by competing for ssDNA binding sites. The RecO and RecR, and possibly the RecF proteins, all facilitate RecA loading onto SSB-coated ssDNA. The RecX protein blocks RecA filament extension, and may have other effects on RecA activity. The DinI protein stabilizes RecA filaments. The RdgC protein binds to dsDNA and blocks RecA access to dsDNA. The PsiB protein, encoded by F plasmids, is uncharacterized, but may inhibit RecA in some manner. The UvrD helicase removes RecA filaments from RecA. All of these proteins function in a network that determines where and how RecA functions. Additional regulatory proteins may remain to be discovered. The elaborate regulatory pattern is likely to be reprised for RecA homologues in archaeans and eukaryotes.
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Cites
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
Abrahams, J. P., Leslie, A. G. W., Lutter, R., & Walker, J. E. (1994) · Nature · doi:10.1038/370621a0 · Cited by 3,005
Biochemistry of homologous recombination in Escherichia coli
Kowalczykowski, S. C., Dixon, D. A., Eggleston, A. K., Lauder, S. D., & Rehrauer, W. M. (1994) · Microbiological Reviews · doi:10.1128/mr.58.3.401-465.1994 · Cited by 1,250
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
Shinohara, A., Ogawa, H., & Ogawa, T. (1992) · Cell · doi:10.1016/0092-8674(92)90447-k · Cited by 1,248
Chromosomal stability and the DNA double-stranded break connection
van Gent, D. C., Hoeijmakers, J. H. J., & Kanaar, R. (2001) · Nature Reviews Genetics · doi:10.1038/35056049 · Cited by 1,219
Interaction network containing conserved and essential protein complexes in Escherichia coli
Butland, G., Peregrín-Alvarez, J. M., Li, J., Yang, W., Yang, X., Canadien, V., Starostine, A., Richards, D., Beattie, B., Krogan, N., et al. (2005) · Nature · doi:10.1038/nature03239 · Cited by 1,201
The importance of repairing stalled replication forks
Cox, M. M., Goodman, M. F., Kreuzer, K. N., Sherratt, D. J., Sandler, S. J., & Marians, K. J. (2000) · Nature · doi:10.1038/35003501 · Cited by 1,044
Self-citationRecombinational Repair of DNA Damage in Escherichia coli and Bacteriophage λ
Kuzminov, A. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.4.751-813.1999 · Cited by 896
Catalysis of ATP-Dependent Homologous DNA Pairing and Strand Exchange by Yeast RAD51 Protein
Sung, P. (1994) · Science · doi:10.1126/science.8066464 · Cited by 866
gisela-storz (2000) · Cited by 866
ISOLATION AND CHARACTERIZATION OF RECOMBINATION-DEFICIENT MUTANTS OF ESCHERICHIA COLI K12
Clark, A. J., & Margulies, A. D. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.53.2.451 · Cited by 825
Cited by
Mutation as a Stress Response and the Regulation of Evolvability
Galhardo, R. S., Hastings, P. J., & Rosenberg, S. M. (2007) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230701648502 · Cited by 643
Recombination and the maintenance of plant organelle genome stability
Maréchal, A., & Brisson, N. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2010.03195.x · Cited by 533
The RdgC protein employs a novel mechanism involving a finger domain to bind to circular DNA
Briggs, G. S., Yu, J., Mahdi, A. A., & Lloyd, R. G. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq509 · Cited by 13
Engineered RecA Constructs Reveal the Minimal SOS Activation Complex
Cory, M. B., Li, A., Hurley, C. M., Hostetler, Z. M., Venkatesh, Y., Jones, C. M., Petersson, E. J., & Kohli, R. M. (2022) · Biochemistry · doi:10.1021/acs.biochem.2c00505 · Cited by 12
(2024) · doi:10.1016/j.isci.2024.111259 · Cited by 3
Metadata
- Authors
- Cox, M. M.
- Venue
- Critical Reviews in Biochemistry and Molecular Biology
- Publisher
- Informa UK Limited
- Published
- 2007-01
- Volume
- 42
- Issue
- 1
- Pages
- 41-63
- ISSN
- 0045-6411 (ISSN-L)
- 1040-9238
- 1549-7798
- OpenAlex
- W2084802036
- Cited by
- 417
- References
- 212
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- closed
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